KEGG   Ornithorhynchus anatinus (platypus): 100084645Help
Entry
100084645         CDS       T01045                                 

Gene name
SOS2
Definition
son of sevenless homolog 2 (Drosophila)
Orthology
K03099  
son of sevenless
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Chemokine signaling pathway
FoxO signaling pathway
PI3K-Akt signaling pathway
Dorso-ventral axis formation
Focal adhesion
Gap junction
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Neurotrophin signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Prolactin signaling pathway
Alcoholism
Hepatitis C
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Endometrial cancer
Glioma
Prostate cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:oaa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100084645 (SOS2)
   04010 MAPK signaling pathway
    100084645 (SOS2)
   04012 ErbB signaling pathway
    100084645 (SOS2)
   04630 Jak-STAT signaling pathway
    100084645 (SOS2)
   04068 FoxO signaling pathway
    100084645 (SOS2)
   04151 PI3K-Akt signaling pathway
    100084645 (SOS2)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100084645 (SOS2)
  Cellular commiunity
   04510 Focal adhesion
    100084645 (SOS2)
   04540 Gap junction
    100084645 (SOS2)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100084645 (SOS2)
   04660 T cell receptor signaling pathway
    100084645 (SOS2)
   04662 B cell receptor signaling pathway
    100084645 (SOS2)
   04664 Fc epsilon RI signaling pathway
    100084645 (SOS2)
   04062 Chemokine signaling pathway
    100084645 (SOS2)
  Endocrine system
   04910 Insulin signaling pathway
    100084645 (SOS2)
   04912 GnRH signaling pathway
    100084645 (SOS2)
   04915 Estrogen signaling pathway
    100084645 (SOS2)
   04917 Prolactin signaling pathway
    100084645 (SOS2)
  Nervous system
   04722 Neurotrophin signaling pathway
    100084645 (SOS2)
  Development
   04320 Dorso-ventral axis formation
    100084645 (SOS2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100084645 (SOS2)
   05206 MicroRNAs in cancer
    100084645 (SOS2)
   05205 Proteoglycans in cancer
    100084645 (SOS2)
   05214 Glioma
    100084645 (SOS2)
   05221 Acute myeloid leukemia
    100084645 (SOS2)
   05220 Chronic myeloid leukemia
    100084645 (SOS2)
   05211 Renal cell carcinoma
    100084645 (SOS2)
   05215 Prostate cancer
    100084645 (SOS2)
   05213 Endometrial cancer
    100084645 (SOS2)
   05223 Non-small cell lung cancer
    100084645 (SOS2)
  Substance dependence
   05034 Alcoholism
    100084645 (SOS2)
  Infectious diseases
   05160 Hepatitis C
    100084645 (SOS2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
4
AA seq 1332 aa AA seqDB search
MQPPQQPYDFFGDENSRKWRGLFVPALRKVQQQVHPNLAAKEDSLYYIEELILQLLSKLC
IAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNLIIKVFREAFLSNRKLFSSYDI
EMIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQEI
LSADFHDHFHNLMSKPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCLHYFELLQQLQE
CSEEEEDRECLKQAITALLNLQCSMERIYRQHSPRRRPGDPVCRFYNRQIRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRLGAKHERHIFLFDGLMISCKTNHGQSRLPG
YSSAEFRLKEKFIMRKIQINDKDDTSECKHAFELVSKDENSIVFSAKSAEEKNNWMAALI
SLQYRSTLDRMLDSVLLKEENEQPLRLPSPELYRFVVKDSEDNIVFEENLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPDPEPTEADRLA
VEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLEKLESFITSVR
GKAMKKWVESIAKIIRRKKQAQANGISHNITFESPPPPIEWHLSRSGQLETFDLMTLHPI
EIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENLEERVAVLSRVIEILQVFQDLNNFNGVLEIVSAVNSVPVYRLDHTFEALQERKRRILD
EAVDLSQDHFKKYLAKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKQGKELINFSKRR
KVAEITGEIQQYQNQPYCLRIEAEIRGFFENLNPMGNTSEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKTTFSLKSPGIRPNAGRHGSTSGTLRGHPTPLEREPCKISFSRITEAEHETTV
SAPTSPNTPSTPPVSASSDLSVFLDIDLNSSYGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLVPPPLPPRKKFDQDASNSKGNLKSGDDPPAIPPRQPPPPKIKPRVPAYGGPFEGPL
HSPPPPPPRDPLPDTPPPVPLRPPEHFVNCPFNLQPPPMGHLHRDPDWFRETSTCPNSPN
TPPSTPSPRVPRRCCMLSSSHNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPLH
RLSLLENAETPQ
NT seq 3999 nt NT seq  +upstreamnt  +downstreamnt
atgcagccgccgcagcagccctacgacttcttcggcgacgagaacagccggaaatggcgg
gggctcttcgtcccggccctacggaaggttcagcagcaagttcacccaaatctcgcagca
aaagaagattccctctattatattgaagagttgattcttcagctgctcagtaaattatgc
atcgcccaaccaaggacagttcaagatgtggaggagcgagttcaaaagacatttccccat
ccaattgacaagtgggccattgctgatgcgcagtctgccattgagaaaaggaaacgaaga
aatcccctcttactacctgtggataaaattcatccatcattaaaggaagtcttaggctat
aaagtagattaccatgtttctctttacatcgtggccgtattggaatatatctcagctgat
attttgaaattagctggtaattatgttttcaatatccgacactatgaaatctcccagcag
gacataaaagtatcaatgtgtgcagataaggttttaatggatatgttcgatcaggacgac
attggtttggtttctctctgtgaagatgagccctcttcttcaggtgaattaaattactac
gacttagttagaactgaaattgccgaagaaaggcagtacctgcgagagctaaatctgatt
ataaaagtgtttcgcgaggctttcctatctaacagaaagctgttttcatcttacgatatt
gaaatgatattcagcaacatttcagatattcatgaattgaccgtgaagcttttaggtcta
attgaggacactgttgaaatgacagatgagagtagtcctcatcctttagctggcagctgt
tttgaagatctggcagaagagcaagcgtttgatccttatgaaaccttgtcacaggagatt
ctctcggcagactttcatgatcatttccataatttgatgtccaaacctgcagttgctctt
cattttcagtccattgctgatggttttaaagaggcagtgcgttatgtccttccacgtctc
atgctggtgccagtttaccattgcctgcactattttgaattattacagcaattacaagaa
tgcagtgaagaagaggaggacagagagtgtttgaaacaagccattactgcgctgttgaat
cttcaatgtagtatggaacggatttataggcagcattcacctagacgacgtcctggggat
ccagtttgtcggttttataaccgtcaaataagaagcaagcacctggccatcaaaaaaatg
aatgaaattcagaaaaatattgatggatgggaaggcaaagatattggccagtgttgtaat
gaatttatcatggaaggtccactaacaagattaggagctaagcatgaacgccatattttt
ctcttcgatggcttgatgatcagttgtaaaacaaatcatggacagtcccggcttccaggt
tacagcagtgcagagtttagactaaaagaaaaatttatcatgaggaaaattcaaatcaat
gataaagatgacactagtgaatgcaagcatgcttttgaattagtttccaaagatgaaaac
agcattgtgttttctgccaagtctgctgaggaaaaaaacaattggatggcagctttaatt
tctcttcagtatcggagtactctggatcgaatgcttgattctgtgttacttaaagaagaa
aatgagcagccactgagacttcccagcccagaattgtatcgttttgttgtgaaagactct
gaagataacattgtttttgaagaaaacttacaaagtaggagtggaattcctataattaaa
ggaggaactgtggtgaaattaattgaaagactaacatatcatatgtatgcagatcctaat
tttgtgcgaactttccttacaacgtatcggtccttttgcaaaccacaggaactgttgagc
ttattgatcgaaaggtttgaaatcccagatcctgagcctacagaagcggataggctggca
gtagagaaaggagagcagcccatcagtgcagaccttaaaaggtttcgcaaggaatatgtc
cagcccgttcaactgaggatactgaatgtgtttcgacactgggttgagcaccatttttac
gactttgagagagatttggaattgcttgaaaaattagaatcttttattacaagtgtaaga
ggaaaagccatgaagaagtgggtagaatcgattgctaaaatcatcaggcggaaaaaacaa
gctcaggcaaatggaatcagccataacattacattcgaaagtccacctccaccaattgaa
tggcatctcagcagatcgggacagttggaaacttttgacctcatgacactccatccgata
gaaattgctcgtcagctaacacttcttgaatctgacctctacagagccgttcagccttcc
gaacttgttggaagtgtgtggactaaagaagataaggagatcaattccccaaatttattg
aaaatgatcaggcatactaccaatcttactctttggtttgaaaagtgtatagtggaagca
gagaaccttgaagaacgagtggcagtgttgagtagagtcatagaaatcctgcaggttttt
caagatttaaacaatttcaatggtgtgttggagatcgtcagtgcagtgaattcagtgcct
gtgtacaggctagaccacacatttgaggcattacaagagaggaaaaggagaattttggat
gaagcagtggacctaagccaagatcactttaaaaaatacctggcaaagcttaaatcaatc
aatccaccctgcgtgcctttttttggaatctatttaacaaatattttgaagactgaagaa
ggaaataatgactttcttaaaaaacaaggaaaagaattaatcaacttcagtaagaggagg
aaagtcgctgaaattactggagaaattcagcagtatcagaatcagccttactgtttgcgg
attgaagcagaaataaggggattctttgaaaatctcaatcctatgggcaatacatctgaa
aaagaatttacagactacttgttcaataaatcacttgaaattgaaccccgaaactgcaaa
cagccacctcgatttcctaggaaaacaactttctctttaaagtctcctggaataaggccc
aatgctggcaggcatggctctacctcaggcactttacgaggtcacccgactcctctagaa
agagaaccgtgtaagataagcttcagtcggattactgaagctgagcacgagacaacagtg
tcagcaccgacgtctccaaacacaccatctactccaccggtctctgcttcctcagacctt
agtgtatttttagatatagatctcaacagttcctatggaagcaacagcatctttgctcca
gttctcttgccccattcaaaatcttttttcagttcatgtggaagtttacataaattaagt
gaagagccactggttcctcctcctcttccacctcgcaaaaagtttgatcaggacgcttca
aattccaagggaaatctgaaatctggtgacgaccctcctgctattccaccaagacagccg
ccacctccaaagataaagccacgtgttcctgcatacggtggtccttttgaaggacctctt
catagtccaccaccaccacctccaagggacccccttccagatactcctccaccagttcca
cttcgcccaccggaacacttcgtcaactgtccgttcaatcttcagccaccaccgatggga
catctccacagagatccagactggttcagagaaaccagtacatgtccaaattccccaaat
actcctccaagcaccccctctccaagggtaccacgccgctgctgtatgctcagttccagt
cacaacaatctcgctcatcctcaagctcccccggttccaccaaggcagaattctagccct
catttacccaaactgcctccaaagacttacaagagggagctttctcatcctcctttgcac
agactgtctttgctagaaaatgcagaaactcctcaatga

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