KEGG   Ovis aries (sheep): 101105303
Entry
101105303         CDS       T03117                                 
Symbol
SYK
Name
(RefSeq) tyrosine-protein kinase SYK isoform X1
  KO
K05855  spleen tyrosine kinase [EC:2.7.10.2]
Organism
oas  Ovis aries (sheep)
Pathway
oas04064  NF-kappa B signaling pathway
oas04072  Phospholipase D signaling pathway
oas04151  PI3K-Akt signaling pathway
oas04380  Osteoclast differentiation
oas04611  Platelet activation
oas04613  Neutrophil extracellular trap formation
oas04625  C-type lectin receptor signaling pathway
oas04650  Natural killer cell mediated cytotoxicity
oas04662  B cell receptor signaling pathway
oas04664  Fc epsilon RI signaling pathway
oas04666  Fc gamma R-mediated phagocytosis
oas05152  Tuberculosis
oas05167  Kaposi sarcoma-associated herpesvirus infection
oas05168  Herpes simplex virus 1 infection
oas05169  Epstein-Barr virus infection
oas05171  Coronavirus disease - COVID-19
oas05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:oas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    101105303 (SYK)
   04072 Phospholipase D signaling pathway
    101105303 (SYK)
   04151 PI3K-Akt signaling pathway
    101105303 (SYK)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101105303 (SYK)
   04613 Neutrophil extracellular trap formation
    101105303 (SYK)
   04625 C-type lectin receptor signaling pathway
    101105303 (SYK)
   04650 Natural killer cell mediated cytotoxicity
    101105303 (SYK)
   04662 B cell receptor signaling pathway
    101105303 (SYK)
   04664 Fc epsilon RI signaling pathway
    101105303 (SYK)
   04666 Fc gamma R-mediated phagocytosis
    101105303 (SYK)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101105303 (SYK)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    101105303 (SYK)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    101105303 (SYK)
   05168 Herpes simplex virus 1 infection
    101105303 (SYK)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101105303 (SYK)
   05169 Epstein-Barr virus infection
    101105303 (SYK)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    101105303 (SYK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oas01001]
    101105303 (SYK)
Enzymes [BR:oas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     101105303 (SYK)
Protein kinases [BR:oas01001]
 Non-receptor tyrosine kinases
  SYK family
   101105303 (SYK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 Kdo ABC1 RIO1
Other DBs
NCBI-GeneID: 101105303
NCBI-ProteinID: XP_042098911
EnsemblRapid: ENSOARG00020000234
Position
2:25810836..25917808
AA seq 628 aa
MGDGANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHDRKAHHYT
IERELNGTYAITGGRAHGSPAELCHYHTQELDGLICLLQKPFNRPPGVQPKTGPFEDLKE
NLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRDESEQIVLIG
SKTNGKFLIRAKDNGSYALCLLHEGKVLHYRIDKDKTGKLSIPGGKNFDTLWQLVEHYSY
KSDGLLRVLTVPCQKIGGQSGNINFRPQLPSSHPGTWSAGGIISRIKSYSFPKRDHRKTR
TSSGNQVDSSTTFNPYEPDRGPWANEREAQREALPMDTEVYESPYADPEEIRPKEVYLDR
KLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQL
DNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEE
CNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYY
KFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSAMLEKGERMGCPPGCPREMYELMTL
CWTYDVENRPGFVAVELRLRNYYYDVVN
NT seq 1887 nt   +upstreamnt  +downstreamnt
atgggtgacggtgccaaccacctgcccttcttcttcggcaacatcactcgggaggaggcg
gaagactacctggtccaggggggcatgagcgatgggctctacctgctgcgccagagccgc
aactacctgggtggcttcgccctgtcagtggcacatgacagaaaggcacatcactacacc
atcgagagggagctgaatggcacctatgccatcacgggtggccgggcccatggcagtcca
gccgagctctgccactaccacacccaggagctggatggcctcatctgcctcctccagaag
cccttcaaccggccaccgggggtgcagcccaagactggcccctttgaggacttgaaggag
aacctcatccgagaatatgtgaaacagacatggaacctacagggtcaagctcttgagcag
gccatcatcagccagaaacctcagctggagaaactgatcgccaccacagcccatgaaaaa
atgccctggttccatggaaaaatctctcgggatgaatctgagcagattgtcctgatagga
tcaaagacaaatggaaagtttttgatcagggccaaggacaacgggtcctacgccctgtgc
ctgctgcacgagggcaaggtgctgcactaccgcatcgacaaggacaaaacggggaagctc
tccatccctggcgggaagaatttcgacactctctggcagctggtcgagcattattcttat
aaatcagatggtttgttaagagttcttacagttccatgtcaaaaaattggtgggcaatcg
ggaaatattaacttccgtccacaacttccaagttctcatcctgggacttggtcagcgggt
ggaataatctcaagaatcaaatcatactccttcccaaagcgtgaccacagaaagacccgc
acatcctcagggaaccaggtggatagttctacaacattcaacccatatgagccagaccga
ggaccgtgggccaacgagagagaagctcagagagaagccttgcccatggacactgaggtc
tacgaaagcccctatgcagaccccgaggagatccggcctaaggaggtctacctggaccgg
aagctgctgaccctggaagacaaggaactaggctctgggaactttgggactgtgaagaag
ggctattaccagatgaaaaaagttgtgaaaacagtggctgtgaaaatcctgaaaaatgag
gccaatgaccctgctcttaaggatgagttattagcagaagcgaatgtcatgcagcagctt
gacaacccttacattgtgcgcatgatagggatatgtgaagctgagtcctggatgctggtc
atggagatggcagaacttggtccactcaacaaatatttacaacagaacaggcatgtcaag
gataaaaacatcatagagctggttcatcaggtgtctatgggaatgaaatatttggaagag
tgcaattttgtgcacagagatctggctgcaaggaatgtattgctggttactcaacattat
gccaagatcagtgattttggactttccaaagcacttcgtgctgatgaaaactactacaag
gcccagacccatggaaagtggcctgtgaagtggtacgctccagaatgcatcaactactac
aagttctccagcaaaagtgatgtttggagcttcggagtgttaatgtgggaagcgttttcc
tatgggcagaagccatatcggggaatgaaaggcagtgaagtttctgctatgctggagaaa
ggagagaggatggggtgcccaccagggtgtccgagagagatgtacgagctgatgaccctg
tgctggacctatgacgtggagaacaggcctggattcgtagctgtggaactgcggctgcgc
aattactactacgacgtggttaactaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (17)   
   KEGG PATHWAY (17)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (9)   
   RefSeq(pep) (9)   
DNA sequence (9)   
   RefSeq(nuc) (9)   
Protein domain (6)   
   Pfam (6)   
All databases (51)   

Download RDF
DBGET integrated database retrieval system