KEGG   Ovis aries (sheep): 101112816
Entry
101112816         CDS       T03117                                 
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3 isoform X2
  KO
K11218  Janus kinase 3 [EC:2.7.10.2]
Organism
oas  Ovis aries (sheep)
Pathway
oas04062  Chemokine signaling pathway
oas04151  PI3K-Akt signaling pathway
oas04217  Necroptosis
oas04550  Signaling pathways regulating pluripotency of stem cells
oas04630  JAK-STAT signaling pathway
oas04658  Th1 and Th2 cell differentiation
oas04659  Th17 cell differentiation
oas05161  Hepatitis B
oas05162  Measles
oas05166  Human T-cell leukemia virus 1 infection
oas05169  Epstein-Barr virus infection
oas05200  Pathways in cancer
oas05203  Viral carcinogenesis
oas05223  Non-small cell lung cancer
oas05340  Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:oas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    101112816 (JAK3)
   04151 PI3K-Akt signaling pathway
    101112816 (JAK3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    101112816 (JAK3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    101112816 (JAK3)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    101112816 (JAK3)
   04659 Th17 cell differentiation
    101112816 (JAK3)
   04062 Chemokine signaling pathway
    101112816 (JAK3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101112816 (JAK3)
   05203 Viral carcinogenesis
    101112816 (JAK3)
  09162 Cancer: specific types
   05223 Non-small cell lung cancer
    101112816 (JAK3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101112816 (JAK3)
   05161 Hepatitis B
    101112816 (JAK3)
   05162 Measles
    101112816 (JAK3)
   05169 Epstein-Barr virus infection
    101112816 (JAK3)
  09163 Immune disease
   05340 Primary immunodeficiency
    101112816 (JAK3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oas01001]
    101112816 (JAK3)
Enzymes [BR:oas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     101112816 (JAK3)
Protein kinases [BR:oas01001]
 Non-receptor tyrosine kinases
  JAK family [OT]
   101112816 (JAK3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase FERM_F2 FERM_F1 Jak1_Phl Kdo ABC1 LRR_RI_capping SH2 FERM_C_FAK1 Haspin_kinase
Other DBs
NCBI-GeneID: 101112816
NCBI-ProteinID: XP_027825238
EnsemblRapid: ENSOARG00020006264
Position
5:5076758..5093668
AA seq 1104 aa
MAPPSEETPLISQRSCSLSSSEAGALHVLLPPRGPGPPQCLSFSFGDHSAEDLCVYAAKA
SGILPVYHSLFALALEDLSCWFPPSHIFSVEDTGTQVLVYRLRFYFPNWFGLERCHRFGL
RKDLASAILDLPVLEHLFAQHRHDLVSGRLRVGLSLKEQGECLSLAVLDLARMALEEAQR
PEELLKTVSYKVCLPPGLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMVKYIM
DLERLDPDRAAETFRVGLPGAAGGQDTPGLLRVAGGSGIAWSPGEHEVLQPFCDFPEIVD
ISIKQAPCIGPAAEHRLVTITRTDNQILEAEFPGLPAALSFVALVDGYFRLTTDSRHYFC
KEVAPPRLLEEVAEQCHGPITLDFAINKLKTEGSRPGSYVLRRSPQDFDSYLLTVCVLTP
LGPDYKGCLIRCDPTGTFSLAGLGRSHSSLRELLAACWNGGLHVDGVELYLTFCCNPRPK
EKSNLIVVRRGCNPPTSSPVQPQFQCQLSQMTFHKIPADSLQWHENLGHGSFTKIYRGCH
HEIVDGEARETEVLLKVMDAKHKNCMESFLEAASLMSQVSYQHLVLLHGVCMAGDSIMVQ
EFVRLGALDTYLRKCGHLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGT
DGNLPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATVWEVFS
GITVPISTLEPAKKLQFYQERQQLPAPKWTELALLIQQCMAYEPGQRPSFRAVIRDLNSL
ITSDYELLSDPTPGTLAPRDGLWNGTQLYACQDPTIFEERHLKYISQLGKGNFGSVELCR
YDPLGDNTGALVAVKQLQHSGPEQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL
VMEYLPSGCLRDFLQRHRARLDAGRLLLYASQICKGMEYLGSCRCLHRDLAARNILVESE
THVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL
FTYSDKNCSPSAEFLRMMGCERDVPALCRLLELLAEGQRLPAPPACPSEVHELMKLCWAP
NPQDRPSFSALGPQLDALWSGSRG
NT seq 3315 nt   +upstreamnt  +downstreamnt
atggcacctccaagtgaggagacacccctgatttctcagcggtcctgcagcctctcctct
tcagaggctggtgcgctgcacgtgctgctgccccctcggggccctggacccccacagtgc
ctgtccttctcttttggggaccactcagctgaagacctgtgtgtttacgctgctaaggcc
agtggcatcctgcccgtgtaccactccctctttgctctggctttggaagacctgtcttgc
tggttccccccgagccacatcttctccgtggaggacacgggtacccaggttctcgtctac
aggctccgcttttacttccccaactggtttggactagagaggtgccaccggtttgggcta
cgaaaggacttggccagcgccatcttggatctgccagtcctggagcacctctttgctcag
caccgccatgacctggtgagcggccgcctccgggtaggcctcagcctcaaggaacagggt
gagtgtctcagcttggctgttctggacctggcccggatggccctcgaggaggctcagcgg
cccgaggagttgctgaagacggtcagctacaaggtctgcctgccccctggcctacgcgac
ctgatccagggtttgagcttcgtgactcggaggcgcatccgaaggacagtgcgccgggcc
ttgcgccgcgtggcggcctgccaggctgacaggcactcgctcatggtcaagtacatcatg
gacctcgagcggctggatccagacagggccgccgagactttccgcgtgggtctccccggc
gctgctggtggtcaggatacgccggggctgctccgtgtggctggtggcagtggcatcgcc
tggagcccaggagaacacgaggtcctccagcccttctgcgactttccagaaatcgtggat
atcagcatcaagcaggcgccgtgcattggcccggctgcggagcatcgcctggttaccatc
accaggacagacaatcagatcctggaggccgagttcccggggcttcccgcagcgttgtcc
ttcgtggcgctcgtggatggctacttccggctgaccacggactcgcggcactacttctgc
aaggaggtggcgccgccgcggctgctggaggaggtggctgagcagtgccatggccccatc
accctggattttgccatcaacaaactcaagactgagggctcacgtcccggctcctatgtc
ctccgccgcagtccccaggatttcgacagctacctcctaactgtttgtgtcctgaccccg
ctgggcccggattataagggctgcctcatccggtgcgaccccacaggaaccttttccctg
gctggccttggccgttcccacagcagtcttcgagagctcctggcagcctgttggaatggt
gggttgcatgtggatggggttgagctatacctcaccttctgctgcaaccccagacctaaa
gaaaagtccaatctgattgtggtccggagaggctgcaacccacccacatcatcccctgtt
cagccccaattccagtgccagctgagtcagatgacgtttcataagatccctgctgacagc
ctgcagtggcatgagaacctaggtcacgggtccttcaccaagatttatcggggctgtcac
catgagattgtggatggggaggcccgagagacagaggtgctgctcaaagtgatggacgcc
aagcacaagaattgcatggagtcattcctggaagcagcgagcttgatgagccaagtgtca
taccagcatctcgtattgctccacggcgtgtgcatggctggagacagtatcatggttcag
gaatttgtacgcctgggagcactggacacatatctacgcaagtgtggccacctagtgcca
gccagctggaagctacaggtgatcaaacagctggcctatgccctcaactatctggaagac
aaaggtctccctcatggcaatgtctcagcccggaaggtgctcttggctcgtgaggggact
gatgggaacctccctttcatcaagctgagtgacccgggtgtcagccccactgtgctaagc
ctggagatgctcactgacaggatcccctgggtggcccctgaatgtctccaggaggcccga
acacttggcttggaagctgacaagtggggctttggagccacagtctgggaggtgttcagt
ggtatcacagtgcccatcagcaccctggagcctgccaagaagctccagttttaccaggaa
cggcagcagttgcctgcccccaagtggacggagctggccctgctgatccaacagtgcatg
gcctatgagccaggccagaggccctctttccgcgctgtcatccgtgacctgaacagtctc
atcacttcagattatgagctcctctcagaccccacacctggcaccctggcgccccgtgat
gggctctggaatggcacccagctctacgcctgccaggaccctaccatctttgaagagaga
cacctcaagtacatctcacagctgggcaagggcaactttggcagcgtggagctgtgccgc
tatgacccgctgggcgacaacacaggggccctggtggccgtgaagcagttgcagcatagt
gggccagaacagcagcgggacttccagcgggagatccagatcctcaaagcgctccacagc
gacttcattgtcaagtaccggggtgtcagctatggcccaggccgccagagcctgcggttg
gtcatggagtatctgcccagtggctgcctgcgcgacttcctgcagcggcaccgcgcccgc
ctcgacgctggccgcctgctcctctacgcctcacagatctgcaagggcatggagtacctg
ggctcctgccgctgcctgcaccgcgacctggcagcccggaacatcctggtggaaagcgag
acgcacgtcaagatcgccgacttcggcctcgccaagctgctgcctctcgacaaagactac
tacgtggtccgcgagccaggccagagccccatcttctggtatgccccagagtccctctcg
gacaacatcttctcgcgccagtcggatgtctggagcttcggggtcgtcctgtacgagctc
ttcacctacagtgacaagaactgtagcccctcagccgagttcctgcggatgatgggatgt
gagagagatgttccagccctctgccgcctcctggagctgttggccgagggccagaggctg
cccgcacctcctgcctgtcctagtgaggttcatgagctcatgaagctgtgctgggcccct
aaccctcaagaccggccatcgttcagtgccctgggcccccagctggatgcactgtggagt
ggaagccggggatag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (15)   
   KEGG PATHWAY (15)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (11)   
   Pfam (11)   
All databases (42)   

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