KEGG   Ovis aries (sheep): 101115458
Entry
101115458         CDS       T03117                                 
Symbol
APC2
Name
(RefSeq) adenomatous polyposis coli protein 2 isoform X1
  KO
K02085  adenomatosis polyposis coli protein
Organism
oas  Ovis aries (sheep)
Pathway
oas04310  Wnt signaling pathway
oas04390  Hippo signaling pathway
oas04550  Signaling pathways regulating pluripotency of stem cells
oas04810  Regulation of actin cytoskeleton
oas04934  Cushing syndrome
oas05010  Alzheimer disease
oas05022  Pathways of neurodegeneration - multiple diseases
oas05165  Human papillomavirus infection
oas05200  Pathways in cancer
oas05206  MicroRNAs in cancer
oas05210  Colorectal cancer
oas05213  Endometrial cancer
oas05217  Basal cell carcinoma
oas05224  Breast cancer
oas05225  Hepatocellular carcinoma
oas05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:oas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    101115458 (APC2)
   04390 Hippo signaling pathway
    101115458 (APC2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    101115458 (APC2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101115458 (APC2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101115458 (APC2)
   05206 MicroRNAs in cancer
    101115458 (APC2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101115458 (APC2)
   05225 Hepatocellular carcinoma
    101115458 (APC2)
   05226 Gastric cancer
    101115458 (APC2)
   05217 Basal cell carcinoma
    101115458 (APC2)
   05213 Endometrial cancer
    101115458 (APC2)
   05224 Breast cancer
    101115458 (APC2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    101115458 (APC2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101115458 (APC2)
   05022 Pathways of neurodegeneration - multiple diseases
    101115458 (APC2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101115458 (APC2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:oas01009]
    101115458 (APC2)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:oas03036]
    101115458 (APC2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:oas04812]
    101115458 (APC2)
Protein phosphatases and associated proteins [BR:oas01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     101115458 (APC2)
Chromosome and associated proteins [BR:oas03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centriole associated proteins
    101115458 (APC2)
Cytoskeleton proteins [BR:oas04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     101115458 (APC2)
SSDB
Motif
Pfam: APC_basic APC_rep APC_N_CC Arm APC_r Arm_APC_u3 Suppressor_APC SAMP Wtap Sec7-like_HUS bZIP_1 MPS2 CCDC138_cc Sec2p HALZ Herpes_BLRF2
Other DBs
NCBI-GeneID: 101115458
NCBI-ProteinID: XP_027825999
EnsemblRapid: ENSOARG00020016161
Position
5:41527093..41551936
AA seq 2277 aa
MGLLGLLSLLHSAFFGDQALQALKMTSSVAAYEQLVRQVEALKAENSHLRQELRDNSSHL
SKLETETSGMKAVLQHLQGKLEQEARVLVSSGQTEVLEQLKALQMDITSLYNLKFQPPAL
APEPTTRTPEGSPVHSSGPSKENFGELSRATIRLLEELDRERCFLLNEIEKEEKEKLWYY
SQLQGLSKRLDELPHVETQFSMQMDLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRA
SRLEQIDKELLSAQDRVQQTEPQALLAVKSMPMDEDAENEVPTHPEDGAPQPGNSKVEVV
FWLLSMLATRDQEDTARTLLAMSSSPESCVAMRRSGCLPLLLQILHGTEAGLGGRNGTPG
APGAKDARMRANAALHNIVFSQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQAQDGGPE
GGGTGAAPVPIEPQICQATCAVMKLSFDEEYRRAMNELGGLQAVAELLQVDHEMHKMTRD
PLNLALRRYAGMTLTNLTFGDVANKAALCARRGCMEAIVAQLASESEELHQVVSSILRNL
SWRADINSKKVLREVGSMTALMQCVLRATKESTLKSVLSALWNLSAHSTENKAAICQVDG
ALGFLVSTLTYKCQSNSLAIIESGGGILRNVSSLIATREDYRQVLRDHNCLQTLLQHLTS
HSLTIVSNACGTLWNLSARSPRDQELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLA
HRPAKYQPAATAVSPGSCAPSLYVRKQRALEAELDTRHLAQALDHLEKQGLPEAEAASKK
PLPPLRHLDGLAQDYASDSGCFDDDDAPSLAAAATATEPASPAVLSLFLGSPFLQGQALA
RAPPTRRGGLEVEKEAGGEAAVAARAKAKLALAVARIDRLVEDISALHTSSDDSFSLSSG
DPGQEAPREGRAQSCSPCRGPEGGRREVGSSRAHPLLRLKAAHASLSNDSLNSGSTSDGH
CPREHSRPCSLAALAEHREGPPRGQARPSQLDLSLPSGQAEPEARDAKATDAHVRTIKLS
PTYQHVPLLEGTTRVGVGSLAPGARKQAWLSTEGLSSVPEKLMVEKAPLCLSRCSSLSSL
SSAGRPGPSEAGDLDESDSSLEGLEESGPGEAELDGAWRGPGTASLPMAIPAPQRGRGLG
VEDATPSSSSENCVQETPLVLSRCSSVSSLGSFESPSIASSIPSDPCSGLGSGTVSPSEL
PDSPGQTMPPSRSKTPPLAPAPPGEREATQFSLQWESYVKRFLDIADCRERCRLPSELDA
GSVRFTVEKPDENFSCASSLSALALHELYVQKDVELRLLPPACPERGSGGGGGPGHRRRD
EASGCLEGPASTDQELELLRECLGGAVPARLRKVASALVPGRRALPVPVYMLVPAPAHED
DSCTDSAEGTPVNFSSTASLSDETLQGPPKDGRRLDGQKPAGHAASTRQSAGQRHRVGGM
GRSTEQPQGAGRSLAGLELPLRRPPSACRDTDSSRPGREHGDGALQSLCLTTPTEEAVYC
FYGNDSDEEPATAVAAAPPRRASAIPRAVKRERPAGARKEVQAVPKAAPKAAPPTRAQPS
LIADETPPCYSLSSSASSLSEPEPSECMASRARVHKPGLTKDLVSGGRKDGSLSPRAEAE
LLRRCIGSALPRRQPQVSGPRRRPPREAQPKEHAAEGPWERGEEATSSDHASDLDSIEWR
AIQEGANSVATWLHQAAAAAAREASSESDSVLSFATGQSVGSTLQPTLHRKGCRPRAERQ
ASGALRPEKPEGALTQRSSGPEKPRSTQKAPNGVPAVLRGHTVIYMPSPATRAQPRGAPG
SRIVARKMGAPSPVQPAAPTKAPSLGQQRSRSLHRPGKISELSTLSPPQRSATPPARLAK
TLLSSSSQTSPASQPLPRRSPPAAQPAGPLPGPKASPVPKTPARALLAKQHKTQKSPVRI
PFMQRPARRGPPPLARAAPEPGPRGRVGTEGGPAARGGRLGLVRVASARSSGSESSDRSG
FRRQLTFIKESPGLLRRRRSELSAPEATNPTTQAASPCRGRPTLPAVFLCSSRCDELRAG
SRQAPAPQRAHAARPRPSERQPRRTSSESPSRLPVRTPAAGPETVKRYASLPHISVARRP
DATSPEPAADATRRSSAGEAGPLPRVAAPGTTWRRIRDEDVPHILRSTLPARALPLLGSP
PEDGPAGPPQRKTSDAVVQTEDFAAAKINSSTSPSMESRAPPQATASGPTSLLGSDVDGP
PAKAPAPTPFVPASRHGSPSRSARVPPFNYVPSPMVAATADSAVEKAPTPVPTSLLE
NT seq 6834 nt   +upstreamnt  +downstreamnt
atggggctcctggggctgctgagcctgctgcactcggccttctttggggaccaggcactg
caggcgctgaagatgacgagctccgtggcagcctatgagcagctggtgcggcaggtggag
gccttgaaggccgagaacagtcacctgcggcaggagcttcgggataattcaagccacctg
tccaagctggagacagagacgtcgggaatgaaggcggtcctgcagcacttacagggcaag
ctggagcaggaggctcgtgtgttggtgtcctccgggcagactgaggtgctggaacagctg
aaagccctgcagatggacatcaccagcctgtataacctcaagttccagcccccagctctg
gcccccgaacccactacccggacccctgagggaagcccggtgcacagctctgggccctcc
aaggagaactttggggagctgagccgggctaccattcggctcttggaggaactggacagg
gaacggtgtttcctgttgaatgagattgagaaggaggaaaaggagaagctctggtattac
tcgcagttgcaggggctatctaagcgcttggatgaactcccgcacgtggagacgcagttc
tcaatgcagatggatctgatccggcaacagctggaattcgaggcccagcacatccgctcg
ttgatggaggagcgcttcggcacctcggacgagatggtgcagcgggcgcagatccgtgct
tcccgcctggagcagatcgacaaggaactgctatctgcccaggaccgggtgcagcagacc
gagccccaggccttgctggcagtgaagtcgatgcccatggacgaggacgccgagaatgag
gtccccacgcaccctgaggatggtgcccctcagccaggcaacagtaaggtggaggtggtc
ttctggctcctgtccatgctggcaacgcgggaccaggaggacacggcacggacgctgctc
gccatgtccagctcacctgaaagctgtgtggccatgcgccgctcaggctgtctgccactg
ctgctgcagatcctgcacggcaccgaggccgggcttgggggtcgcaacgggacccctggg
gctccaggagccaaggacgcacgcatgcgcgccaatgcagcactgcacaatattgtcttc
tctcagcccgaccaggggctggcacgcaaggagatgcgggtgttacacgtgctggagcag
atccgtgcctactgcgagacctgctgggactggctgcaggcccaggatggcgggcctgag
ggcggcggcaccggtgctgcaccggtgcccatcgagccacagatctgtcaggccacctgc
gccgtgatgaagctgtcctttgacgaggaataccgccgcgctatgaatgagctgggtggg
ctgcaggcagtggcggagttactgcaggttgaccatgagatgcacaagatgacccgggac
cctctcaacctggccctgcgccgatacgccggcatgaccctcaccaaccttaccttcggg
gatgtcgccaacaaggctgcactgtgcgcccgccggggctgcatggaggccattgtggcc
cagctggcatctgagagtgaggagctgcaccaggtcgtgtctagcatcctgcgcaacctg
tcctggagggctgacatcaacagcaagaaggtgctgagggaggtgggcagcatgactgcc
ctgatgcagtgcgtccttcgagccaccaaggagtccaccctgaagagcgtgcttagcgcc
ctgtggaacctctcagcgcacagcacagagaacaaggcagccatctgccaggtggatggt
gccctcggcttcctggtgagcacactgacttacaagtgccagagcaactcgctagccatc
attgagagtggtggcggcatccttcgcaatgtgtccagcctcatcgccaccagagaggac
tacaggcaggtgctgcgagaccacaattgcctgcagacgctgctgcagcatctgacgtcg
cacagcctgaccatagtgagcaatgcgtgcggcacgctctggaacctgtcggcccgcagc
cctcgagaccaggagctgctgtgggacctgggcgccgtgggcatgctgcggaacctggta
cactccaagcacaagatgatcgccatgggcagcgccgccgcgctgcgcaacctgctggct
caccggcctgccaagtaccagccagcggccaccgcggtctccccgggctcctgcgcgccc
agcctgtatgtgcgcaaacagcgcgcactggaggccgagctggacacacggcacctggcg
caggcgcttgaccacctggagaagcagggcctgccggaggccgaggccgcctccaagaag
cccctcccgcccctacgccacctggacggcctggcgcaggactacgcctctgactcgggc
tgttttgacgacgacgatgcgccctccctggctgctgctgccactgccacagagcccgcc
agccccgcagtgctctccctcttcctgggcagccccttcctgcagggccaggcgctggcc
cgagccccgcccacccgccgaggaggcctggaggtggagaaggaggccggtggggaggca
gccgtggcagctagggccaaggccaagctggcgctagcagtggctcgcatcgacaggctg
gtagaggacatctcggccctgcacacttcatctgacgacagcttcagcctcagctccggg
gaccctggccaggaggccccgagagaaggccgtgcccaatcctgctcaccttgcaggggg
cctgaggggggacggcgggaagtgggcagcagccgggctcacccactgctgcgactcaag
gcagcccacgccagcctttccaatgacagtctcaacagcggtagcaccagtgatgggcac
tgtcctcgtgaacactcacggccctgctcgctggctgctctggctgagcaccgagagggg
cccccacgtggtcaggcgcggcccagccagcttgacctcagcctgcccagtggccaggct
gagcctgaggcccgggatgccaaggccacagatgcccatgtgcgtaccatcaagttgtcg
cccacctaccagcacgtgccgctgttggagggcaccactagggtgggtgtggggtccctg
gcccctggggcccgaaaacaggcctggctgtccacggagggcctgagcagtgtgcctgag
aagctaatggttgagaaggcacccctctgcctgtcccgctgcagctcgctgtcctcgctg
tcctcagctggccgcccggggcccagtgaggctggggacctagacgagagcgactcatct
ctggaagggctggaggagtctggccctggtgaggcagagctggatggggcctggcggggc
ccagggaccgcctccctgcccatggccatcccagcgccccagaggggtcggggcctgggg
gtggaggatgccacgccgtccagctcctctgagaactgtgtgcaggagacaccgctggtg
ctgagccgctgcagctcagtcagttcactgggcagcttcgagagtccatccattgccagc
tccatccccagtgacccgtgcagcgggctgggcagtggcacagtcagccccagtgagctg
cctgatagccccgggcaaaccatgccgccgagccgcagcaagacaccgccactggctcca
gcaccaccgggcgagcgggaggccacccagttcagccttcagtgggagagttatgtgaag
cgcttcctggacatcgccgactgccgggagcgctgccggctgccctccgagctggatgca
ggcagcgtgcgtttcactgtggagaagcccgacgagaacttttcatgtgcctccagcctc
agcgcattggccctgcacgagctctatgtgcagaaggacgtggagctgcggttactgccc
cctgcctgcccagagcgcggcagtgggggaggcggaggcccggggcaccgccgacgggac
gaggccagtggctgtctggaagggccagcgtccaccgatcaggagctggagctgctgcgc
gagtgcctgggtggggccgtgcctgcccggctccgcaaggtggcctcagcactggtgcct
ggccgccgtgcgctgcccgtgccggtgtacatgctggtgcctgccccggcccatgaggat
gactcctgcactgactcagccgagggcactccagtcaacttctccagcaccgcttccctc
agtgacgagaccctgcagggaccccccaaggatggtaggcgtttggatgggcagaaaccc
gcaggtcatgccgcctccactaggcagtctgctgggcagcggcacagggtggggggcatg
ggccggagcacagagcagccccagggggctggcaggagcctggcagggctagagctgccc
ctccgccggcccccgagcgcctgcagggatactgacagctcccgcccaggccgggagcat
ggggacggggctctgcagtctctgtgcctcacaacgcccaccgaggaggctgtgtactgt
ttctatggcaatgactcggatgaggagccggccacggcggtggcagcagcacccccacgg
cgtgcatccgcgatcccccgggcggtaaagagggagcgcccggctggtgccaggaaggag
gtgcaggctgtgcccaaggctgcacccaaggcagcaccacccacccgggcccagcccagc
ctcattgcagatgagacaccaccgtgctactccctgagctcctccgccagctccctcagc
gaacctgagccctctgagtgcatggccagtcgggcccgggtccacaagccagggctcacc
aaggacctggtctccgggggcaggaaggatggctccctcagcccgcgggccgaggcagag
ctgctccggcgctgcatcggctcagccttgcccaggcgccagccccaggtgtctggccca
aggcgccgcccaccccgagaggcccagccaaaggagcatgcagcagaggggccctgggag
cgcggtgaggaggcaaccagctcagaccatgcctcagacctggacagcatcgagtggcgt
gccatccaggagggcgccaattctgttgccacatggttgcaccaggccgcagcggcggcc
gcccgcgaggcctcctcagagtctgattccgttctgtcctttgcaacagggcagtctgtg
ggttccaccctgcagcccaccctgcataggaaggggtgtcggccaagggcagagcgccag
gcgagtggtgccctgcggccagagaaaccagaaggggccctcacccaacgcagcagtggg
ccagagaagccgcgtagcactcagaaggccccaaatggggtgccagcagtgctccgggga
catacagtgatctacatgcccagccccgccacccgggcacagcccagaggtgcccctggt
tcccgcattgtggcgagaaagatgggagcgcccagccccgtgcagccagcggcccccact
aaagcccccagcctagggcagcagcggtctaggagcctgcaccggcctggcaagatctca
gagctgtcaacgctcagccccccgcagagaagtgccacaccaccagcccgccttgcgaag
accctgttgtcaagctcctctcagacctcaccggcctcccagcctctgcccaggaggtca
ccccctgctgcccagcctgcagggcccctgcctggccccaaggcctccccagtgcccaag
actccagcaagggccctgctggccaagcagcacaagacgcagaagtcacccgtgaggatc
cccttcatgcagaggcccgccaggcgggggccgccgcccttggctagggcagccccggag
ccaggccccaggggccgggtgggcacagaaggcggccctgcagcccgagggggccgcctg
ggcctggtgcgcgtggcctccgcccgctccagcggcagcgaatcctccgaccgctcgggt
ttccggcggcagctgacctttatcaaggagtcgccgggcctgctgcgccgccgacgctct
gaactgtccgcacccgaagccaccaacccgaccacccaggctgcctcgccctgccgcggc
cggcccacactacccgctgtcttcctctgctcctcgcgctgtgatgagctgcgggcaggc
tcccggcaggccccggcccctcagcgggcccacgcggcccggccccgccccagcgagcgg
cagcctcggcgcactagctccgagagcccgtcccgcctgcccgtccgcacgccggccgcc
gggcccgagacggtcaagcgctacgcctccctgccccatatcagcgtggcccgcagaccg
gatgccaccagccccgaacctgcggcggacgccacacgccgcagcagcgcaggagaggcc
gggccgctgcctagggtggccgcgccgggcaccacgtggcgccgcatccgggacgaggac
gtcccgcacatcctgcggagcacgctgcctgcccgcgccctaccgctgctgggctcccct
cccgaggacggcccagccggcccgccgcagcgcaagaccagcgacgccgtggtccagact
gaggacttcgcggctgcgaagatcaactccagcacgtccccgagcatggaaagcagggcg
cccccccaggccacggccagcggccccacctcccttcttggcagcgacgtggatgggccg
cccgctaaggcgcccgcccccacccccttcgtccccgccagccggcacggctcccccagc
cgctctgcccgcgtcccccctttcaactacgtgcccagccccatggtggcggccaccgct
gactccgccgtggagaaggcccccacccccgtccccaccagccttctggaatag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (16)   
   KEGG PATHWAY (16)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (16)   
   Pfam (16)   
All databases (52)   

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