KEGG   Ovis aries (sheep): 101117205
Entry
101117205         CDS       T03117                                 
Symbol
DOCK1
Name
(RefSeq) dedicator of cytokinesis protein 1 isoform X1
  KO
K13708  dedicator of cytokinesis protein 1
Organism
oas  Ovis aries (sheep)
Pathway
oas04148  Efferocytosis
oas04510  Focal adhesion
oas04666  Fc gamma R-mediated phagocytosis
oas04810  Regulation of actin cytoskeleton
oas05100  Bacterial invasion of epithelial cells
oas05135  Yersinia infection
Brite
KEGG Orthology (KO) [BR:oas00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    101117205 (DOCK1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101117205 (DOCK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101117205 (DOCK1)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    101117205 (DOCK1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    101117205 (DOCK1)
   05100 Bacterial invasion of epithelial cells
    101117205 (DOCK1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:oas04131]
    101117205 (DOCK1)
Membrane trafficking [BR:oas04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    101117205 (DOCK1)
SSDB
Motif
Pfam: DOCK_N DOCK-C2 DHR-2_Lobe_C DHR-2_Lobe_A DHR-2_Lobe_B SH3_1 SH3_9 SH3_2
Other DBs
NCBI-GeneID: 101117205
NCBI-ProteinID: XP_014958986
EnsemblRapid: ENSOARG00020024201
Position
22:45861626..46430644
AA seq 1888 aa
MTRWVPTKREEKYGVAFYNYDARGADELSLQIGDAVHILETYEGWYRGYTLRKKSKKGIF
PASYIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRH
MIYDLIEWRSQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTS
TISLFRAHEVASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDA
EVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQ
IVRVGRMELRDNNTRKLTSGLRRPFGVAVMDVTDIINGKVDDEDKQHFIPFQPLALDDAI
RHKPLNMSSRFSPRVAGENDFLQTVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEF
PHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDG
KRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKVAIPIEDVNRSHLRFTFRHRSSQ
DSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKKLEDAGTYLSLPSTKAELEE
KGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNVDLLGLLKWRSSTSLLQQNLRQL
MKVDGGEVVKFLQDTLDALFNIMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLE
TYIKKHFSATLAYTKLTKVLRNYVDNAEKPGISDQLYKAMKALEYIFKFIVRSRILFNQL
YENKGEADFVESLVQLFRSISEMMSSVSDQTVRVKGAALKYLPTIVNDVKLVFDPKELSK
MFTDFILNVPVGLLTIQKLYCLIEIIHSDLFTQHDCREILLPMMTDQLKYHLERQEDLEA
CCQLLSNILEVLYRKDVGPTQRHVQIIMEKLLRTVNRTVISMGRDSELIGNFVACMTAIL
RQMEDYHYAHLIKTFGKMRTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMMQNKVFLRA
INQYADMLNKKFLDQANFELQLWNNYFHLAVAFLTQESLQLENFSSAKRAKILNKYGDMR
RQIGFEIRDMWYNLGQHKIKFIPEMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTR
SFQMFENEIITKLDHEVEGGRGDEQYKVLFDKILLEHCRKHKYLAKTGETFVKLVVRLME
RLLDYRTIMHDENKENRMSCTVNVLNFYKEIEREEMYIRYLYKLCDLHKECDNYTEAAYT
LLLHAKLLKWSEDVCAAHLTQRDGYQATTQGQLKERLYQETIHYFDKGKMWEEAIALGKE
LAEQYENEMFDYEQLSELLKKQAQFYENIVKVIRPKPDYFAVGYYGQGFPTFLRGKVFIY
RGKEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKNSPGQYIQCFTVKPKLDLPPKFHR
PVSEQIVSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEV
KSVFMVEISPLENAIETMQLTNDKINSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFA
NYEKAFFTERYLQEHPEAHEKIEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEA
CFRQLKEKVEKQYGVRTMPSSLDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSSDSTP
SRPGSDGFALEPLLPKKMHSRSQDKLDKDDPDKEKKDKKKEKRNSKHQEIFDKEFKPTDI
PLQQSEAVILSETISPLRPQRPKSQVINAMGGERRFSVSPSSPSSQSTPPPVMPRAKLSF
SLQSSLELNGMAVAGLDVAEVPPPLPLKGTSTDYGTLTENLDLTGSPTPPPPPPHQRHLP
PPLPSKTPPPPPPKTTRKQNSVDSGIVQ
NT seq 5667 nt   +upstreamnt  +downstreamnt
atgacgcgctgggtgcccaccaagcgcgaggagaaatacggcgtggctttttataactat
gatgcgcggggagcggatgaactttctttacaaataggagacgccgtgcacatcctggaa
acgtacgaagggtggtacagaggttacaccttaagaaaaaagtctaagaagggtatattt
cctgcttcgtacatccatcttaaagaagccatagttgaaggaaaagggcaacatgaaacg
gtcatcccaggcgacctcccgctcatacaggaggtcaccacgaccctgcgagaatggtcc
accatctggaggcagctctacgtgcaagataacagggagatgttccgaagcgtccgacac
atgatctacgaccttatcgagtggcggtcgcagattctttctggaactctgccgcaggat
gagctcaaggaattgaagaagaaggtcactgccaaaattgattatggaaacagaatcctc
gatttggacttggtggtgagagatgaagatgggaacattctggatccagaactaactagc
acaatcagtcttttcagagctcatgaagtagcttccaaacaagtggaggaaagattgcaa
gaagaaaaatctcagaagcagaacatagacattaacagacaagccaagtttgccgccacg
ccttctctggccttgtttgtcaacctcaagaacgtggtctgtaaaataggagaagatgcc
gaggtgctcatgtctctgtacgaccctgtggagtccaagttcatcagtgaaaactacctt
gtccgctggtcaagttcaggattgcctaaagacatagacaggttacacaatttgcgagct
gttttcacggacctgggaagcaaagacctgaaaagggagaaaatcagttttgtgtgtcag
atcgtccgtgtgggtcgcatggagctgagggacaacaacacgaggaagctgacgtcgggc
ctgcgacggcctttcggggtggccgtgatggatgtaacggatataataaatgggaaagta
gatgatgaagacaaacagcatttcattccctttcagccgctcgcgttggacgacgccatc
cgacacaagccgctgaacatgtcatcccgtttttcacccagggtggcaggggagaatgac
ttccttcagactgttataaacaaagtcattgctgccaaagaagtcaaccacaagggccag
ggtttgtgggtaacgttgaaattacttcctggagatatccatcagattagaaaagagttt
cctcatttggtggataggaccacagcagtggctcggaagacgggcttcccggagatcatc
atgcctggtgatgttcgaaatgatatctatgtaacattagttcaaggagattttgataaa
ggaagcaagacgacagctaagaatgtcgaagttacggtgtctgtttacgatgaagatgga
aaacggctggagcatgtgattttccccggcgctggtgatgaagcgatttcagagtacaag
tcggtgatttactaccaagtgaaacagccgcgctggtttgagacggttaaggtggccatc
cccatcgaggacgtgaaccgcagtcacctccggtttaccttccgacacagatcgtcccag
gactctaaggacaaatctgagaaaatatttgccctcgcttttgtaaagctcatgcgctac
gatgggaccaccctgagggatggggagcacgatctcatcgtctacaaggcggaagcgaag
aagctggaggacgcgggcacgtacctgagcctgccctccaccaaggccgagctggaggag
aagggccactcggccacaggcaagagcatgcagagcctcgggagctgcaccatcagcaag
gactccttccagatttccacgctcgtgtgctccaccaagctgacccagaacgtggacctg
ctggggctcctgaagtggcgatccagcaccagcctgctgcagcagaacctgaggcagctg
atgaaggtggacggcggagaggtggtgaagttcctccaggacaccttggatgccctcttc
aacatcatgatggagaactcggagagtgagacctttgatacattagtgtttgatgctctg
gtatttatcatcggactaattgctgatagaaaatttcagcattttaatcctgttttggaa
acctacattaagaaacactttagtgcaaccttagcctacacgaagctgacgaaagttttg
cggaactacgtggacaatgccgagaagccgggaataagcgaccagctgtataaagccatg
aaggctctagagtacatcttcaagttcatcgtgcgctcccggatcctgttcaatcagctc
tatgagaacaaaggagaggccgatttcgtggagtccctggtgcagctcttccggtccatc
agcgagatgatgagcagcgtgtcggaccagaccgtccgggtgaagggggcagcgctgaag
tacttgccaactattgtcaacgacgtgaaattggtatttgatcccaaagagctcagcaaa
atgtttactgatttcatcctaaatgtccccgtgggtttgctgaccattcagaagctgtat
tgcttgattgaaataattcacagtgacctcttcacacagcatgactgcagagagatcctg
cttcccatgatgacggatcagctcaagtaccatctggagagacaggaagatctggaggcc
tgctgccaactgctcagcaacatccttgaggttctgtaccggaaggacgtggggccgacg
cagaggcacgtccagatcatcatggagaagcttctccggacagtgaaccgaaccgtcatt
tccatggggcgggactcagaactcatcgggaatttcgtggcctgtatgacagctattctg
cgacaaatggaagactatcattatgcccatttgatcaagacttttgggaagatgaggacc
gatgtggtggatttcctgatggagacattcatcatgtttaagaacctcattgggaagaat
gtctacccgttcgactgggtgattatgaacatgatgcagaataaagtcttcctgcgagca
attaatcagtatgcagatatgctgaacaaaaaatttctggatcaagccaactttgagctg
cagctgtggaacaactattttcacctggccgtcgccttcctcactcaagagtccttgcag
ctggagaatttttcaagtgctaaaagagcgaaaatccttaacaagtacggcgatatgcgg
cggcagattggcttcgagatcagggacatgtggtacaatctcggtcaacacaagatcaag
ttcattccagagatggttggtcccatattggaaatgacgctgattccagagacagagctt
cgcaaagccaccatccccatcttcttcgacatgatgcagtgtgaattccactccacccga
agcttccagatgtttgaaaatgagatcatcaccaagctggatcatgaagtggaaggaggc
agaggcgatgagcagtacaaagtgttatttgataaaatcctcctggagcactgcaggaaa
cacaaatacctcgccaaaacgggagagactttcgtaaagcttgtcgtgcgcctaatggag
agacttctggactacagaaccatcatgcacgatgagaacaaagaaaaccgcatgagctgc
acggtcaacgtgctgaatttctacaaagagattgaaagggaagaaatgtatatacggtat
ttgtacaagctctgtgacctgcacaaggaatgtgataactacactgaagccgcctatacc
ttgctcctccatgcaaagcttctgaagtggtcggaggacgtgtgcgcggcccacctcacc
cagcgggacgggtaccaggcgacgacccaggggcagctgaaggagcggctctaccaggag
accatccactacttcgacaaaggcaagatgtgggaggaggccatcgccctgggcaaggag
ctggcagaacagtatgagaacgaaatgtttgattatgaacagctcagcgaattgctgaag
aaacaggctcagttttatgaaaacatcgtcaaggtgattcgtcccaagcctgactacttt
gccgtcggatactacggacaaggattccccaccttccttcgggggaaagtgttcatttat
cgagggaaagaatatgaacgtcgagaggattttgaagctcggctactgactcagtttcca
aacgctgagaagatgaagacaacgtctccaccaggcgacgacattaaaaactctcctggc
caatatattcagtgcttcacagtaaagcccaaacttgatctgcctcctaaatttcatagg
cccgtgtcagagcagattgtaagtttctacagagtcaacgaagtccagcgatttgaatat
tctcgtccgatccgcaagggagagaaaaacccagacaacgaatttgcgaatatgtggatc
gagaggaccatttataccactgcgtataagctgcctggcatcctgaggtggtttgaggtc
aagtctgtttttatggtggagatcagccccctggagaacgccatcgagaccatgcagctg
accaatgacaagatcaacagcatggtacagcagcacctagacgaccccagccttcccatc
aacccgctctccatgctcctgaacggcatcgtggaccccgcggtcatgggaggttttgcc
aattacgagaaggctttcttcaccgagcggtacctgcaggagcaccccgaggcccacgaa
aagatcgagaagctcaaggacctgattgcttggcagattccgtttttggccgaagggatc
aggatccacggagacaaagtcacagaagcactgaggccatttcatgagagaatggaagcc
tgtttcagacagttaaaggagaaagtggagaagcagtacggcgtccggaccatgccctca
agtctggacgacagaagaggcagccgtccccggtccatggtccgatccttcaccatgcct
tcctcgtcccggcctctatccgtggcttctgtctcctccctctcgtccgacagcacccct
tccaggcctggctccgatgggttcgctctggaacccctcctgccgaagaaaatgcactcc
cggtcccaggacaagctggacaaggatgaccctgacaaagagaagaaggacaagaagaag
gaaaaaaggaacagcaagcatcaagagatattcgataaagaatttaaacccaccgacatt
cccctgcagcaatctgaggctgtgatcctttcagaaacgatcagccccctgcggccccag
agaccgaagagccaggtgatcaacgccatgggtggcgagcggcgcttctcggtgtccccg
tcctccccgtcctcccagtccacgccgcccccagtcatgccgagagccaagctcagcttc
agcctgcagtccagtttggagctgaacggcatggctgtggctgggttggacgtggctgaa
gttccgccccctctgcctctcaaaggcaccagcacggactatgggaccttgaccgagaac
ctggacttgacgggctcgccaacgcccccgccccctccgcctcatcagaggcatctgcct
cctcctctgcccagcaagaccccgccaccaccccctcccaagacgacgcgcaagcagaac
tcggtggactcggggatcgtgcagtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (8)   
   Pfam (8)   
All databases (26)   

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