KEGG   Ovis aries (sheep): 105602258
Entry
105602258         CDS       T03117                                 
Symbol
ADCY5
Name
(RefSeq) adenylate cyclase type 5
  KO
K08045  adenylate cyclase 5 [EC:4.6.1.1]
Organism
oas  Ovis aries (sheep)
Pathway
oas00230  Purine metabolism
oas01100  Metabolic pathways
oas01522  Endocrine resistance
oas04015  Rap1 signaling pathway
oas04022  cGMP-PKG signaling pathway
oas04024  cAMP signaling pathway
oas04062  Chemokine signaling pathway
oas04072  Phospholipase D signaling pathway
oas04114  Oocyte meiosis
oas04211  Longevity regulating pathway
oas04213  Longevity regulating pathway - multiple species
oas04261  Adrenergic signaling in cardiomyocytes
oas04270  Vascular smooth muscle contraction
oas04371  Apelin signaling pathway
oas04540  Gap junction
oas04611  Platelet activation
oas04713  Circadian entrainment
oas04714  Thermogenesis
oas04723  Retrograde endocannabinoid signaling
oas04724  Glutamatergic synapse
oas04725  Cholinergic synapse
oas04726  Serotonergic synapse
oas04727  GABAergic synapse
oas04728  Dopaminergic synapse
oas04750  Inflammatory mediator regulation of TRP channels
oas04911  Insulin secretion
oas04912  GnRH signaling pathway
oas04913  Ovarian steroidogenesis
oas04914  Progesterone-mediated oocyte maturation
oas04915  Estrogen signaling pathway
oas04916  Melanogenesis
oas04918  Thyroid hormone synthesis
oas04921  Oxytocin signaling pathway
oas04923  Regulation of lipolysis in adipocytes
oas04924  Renin secretion
oas04925  Aldosterone synthesis and secretion
oas04926  Relaxin signaling pathway
oas04927  Cortisol synthesis and secretion
oas04928  Parathyroid hormone synthesis, secretion and action
oas04934  Cushing syndrome
oas04935  Growth hormone synthesis, secretion and action
oas04970  Salivary secretion
oas04971  Gastric acid secretion
oas04972  Pancreatic secretion
oas04976  Bile secretion
oas05012  Parkinson disease
oas05030  Cocaine addiction
oas05031  Amphetamine addiction
oas05032  Morphine addiction
oas05034  Alcoholism
oas05163  Human cytomegalovirus infection
oas05166  Human T-cell leukemia virus 1 infection
oas05200  Pathways in cancer
oas05207  Chemical carcinogenesis - receptor activation
oas05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:oas00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    105602258 (ADCY5)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    105602258 (ADCY5)
   04371 Apelin signaling pathway
    105602258 (ADCY5)
   04072 Phospholipase D signaling pathway
    105602258 (ADCY5)
   04024 cAMP signaling pathway
    105602258 (ADCY5)
   04022 cGMP-PKG signaling pathway
    105602258 (ADCY5)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    105602258 (ADCY5)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    105602258 (ADCY5)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105602258 (ADCY5)
   04062 Chemokine signaling pathway
    105602258 (ADCY5)
  09152 Endocrine system
   04911 Insulin secretion
    105602258 (ADCY5)
   04923 Regulation of lipolysis in adipocytes
    105602258 (ADCY5)
   04912 GnRH signaling pathway
    105602258 (ADCY5)
   04913 Ovarian steroidogenesis
    105602258 (ADCY5)
   04915 Estrogen signaling pathway
    105602258 (ADCY5)
   04914 Progesterone-mediated oocyte maturation
    105602258 (ADCY5)
   04921 Oxytocin signaling pathway
    105602258 (ADCY5)
   04926 Relaxin signaling pathway
    105602258 (ADCY5)
   04935 Growth hormone synthesis, secretion and action
    105602258 (ADCY5)
   04918 Thyroid hormone synthesis
    105602258 (ADCY5)
   04928 Parathyroid hormone synthesis, secretion and action
    105602258 (ADCY5)
   04916 Melanogenesis
    105602258 (ADCY5)
   04924 Renin secretion
    105602258 (ADCY5)
   04925 Aldosterone synthesis and secretion
    105602258 (ADCY5)
   04927 Cortisol synthesis and secretion
    105602258 (ADCY5)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105602258 (ADCY5)
   04270 Vascular smooth muscle contraction
    105602258 (ADCY5)
  09154 Digestive system
   04970 Salivary secretion
    105602258 (ADCY5)
   04971 Gastric acid secretion
    105602258 (ADCY5)
   04972 Pancreatic secretion
    105602258 (ADCY5)
   04976 Bile secretion
    105602258 (ADCY5)
  09156 Nervous system
   04724 Glutamatergic synapse
    105602258 (ADCY5)
   04727 GABAergic synapse
    105602258 (ADCY5)
   04725 Cholinergic synapse
    105602258 (ADCY5)
   04728 Dopaminergic synapse
    105602258 (ADCY5)
   04726 Serotonergic synapse
    105602258 (ADCY5)
   04723 Retrograde endocannabinoid signaling
    105602258 (ADCY5)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105602258 (ADCY5)
  09149 Aging
   04211 Longevity regulating pathway
    105602258 (ADCY5)
   04213 Longevity regulating pathway - multiple species
    105602258 (ADCY5)
  09159 Environmental adaptation
   04713 Circadian entrainment
    105602258 (ADCY5)
   04714 Thermogenesis
    105602258 (ADCY5)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105602258 (ADCY5)
   05207 Chemical carcinogenesis - receptor activation
    105602258 (ADCY5)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105602258 (ADCY5)
   05163 Human cytomegalovirus infection
    105602258 (ADCY5)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    105602258 (ADCY5)
  09165 Substance dependence
   05030 Cocaine addiction
    105602258 (ADCY5)
   05031 Amphetamine addiction
    105602258 (ADCY5)
   05032 Morphine addiction
    105602258 (ADCY5)
   05034 Alcoholism
    105602258 (ADCY5)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    105602258 (ADCY5)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    105602258 (ADCY5)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    105602258 (ADCY5)
Enzymes [BR:oas01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     105602258 (ADCY5)
SSDB
Motif
Pfam: AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC
Other DBs
NCBI-GeneID: 105602258
NCBI-ProteinID: XP_027812259
EnsemblRapid: ENSOARG00020010155
Position
1:complement(188526242..188685423)
AA seq 1259 aa
MSSSKSVSPPGYAAQTAAAPASRGGPEHRSAWGEADSRANGYPQAPGGSARGSTKRPGGA
VTPQQQQRLASRWRSDDEDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRR
GAAGGGSTRAPPAGSGGGSAAAAAAAGGTEVRPRSVELGLEERRGKGRAAEELEAGAVEE
DEGSGDGGSSAGSGSGPGTVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQSSL
TMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILVMAVLCNRAAFHQDHMGLAC
YALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALHL
AIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQ
RENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLA
SQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGM
DMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAG
RIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMNRQ
RTNSIGHNPPHWGAERPFYNQLGGNQVSKEMKRMGFEDPKDKNAQESSNPEDEVDEFLGR
AIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQITV
VPHSVFMLSFYLTCFLLLTLVVFVSVIYSCVKLFPAPLQTLSRKIVRSKMNSTLVGVFTI
TLVFLSAFVNMFTCNSKDLFGCLGDEHNISASQVNACHVVESAVNYSLGDEQGFCGSSWP
NCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLVVEVPGVTLFDNADLLV
TANAIDFNNNGTSQCPEHPTKVALKVVTPVIISVFVLALYLHAQQVESTARLDFLWKLQA
TEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSE
FYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDK
VGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNT
VNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPPS
NT seq 3780 nt   +upstreamnt  +downstreamnt
atgtccagctccaaaagcgtgagccccccgggctacgcggcgcagacagcggcggcgccg
gcgtcccggggaggcccggaacaccgctccgcgtggggagaggccgactcccgcgccaat
ggctacccccaagcccccgggggttcggcccgcggctccaccaagagacctgggggggcg
gtgaccccgcagcagcaacagcgcctggccagccgctggcgcagcgacgacgaagacgat
cctccgctgagtggcgatgaccccctggccgggggctttggcttcagctttcgttccaag
tcggcctggcaggagcgcggcggcgacgactgcggtcgcggcagcaggcggcagcggcgg
ggcgcggccggcgggggcagcacccgggcgccccctgcgggcagcggcggcggttcggcg
gctgcggccgccgcagcgggaggaacggaggtgcgcccccgttcggtggagctaggcctg
gaggagcggcgtggcaagggccgcgcggccgaagagctggaggccggcgccgtcgaggaa
gacgaagggtccggggatgggggcagctcggcaggctcgggctcggggcctggcacggtg
ctgtcgctgggcgcctgctgcctggcactgctgcagatattccgctcgaagaagttccca
tcggacaagctggagcggctgtaccagcgctacttcttccgtctgaaccagagcagcctc
acgatgctcatggctgtgctggtgctcgtgtgcctagtcatgttggccttccacgcggca
cggcccccgctgcagctgccctatctggccgtcctagcggccgccgtgggtgtgatcctc
gttatggccgtgctctgcaaccgtgccgccttccaccaggaccacatgggcctggcctgc
tacgcgcttatcgccgtggtgctggccgtccaggtggtgggcttgctgctgccccagccg
cgcagtgcctccgagggcatctggtggactgtgtttttcatctatacgatctacacgctc
ctgcccgtgcgcatgcgggctgcggtactcagcggggtgctcctgtccgccctccacctg
gccatcgccctgcgcacgaacgcccaggatcagttcctgctcaagcagctcgtctccaac
gtcctcattttctcctgcaccaacatcgtgggtgtgtgcacccactacccggctgaggtc
tcgcagagacaggccttccaggagacccgggagtgcatccaggcgcggctccactcgcag
cgggagaaccagcagcaggagcggctcctgctgtctgtccttccccgtcacgttgccatg
gagatgaaagccgacatcaacgccaaacaggaggatatgatgttccataagatttacatc
cagaaacatgacaacgtgagcatcctgtttgctgacatcgagggtttcactagcctggca
tcccagtgcactgcccaggagctggtcatgaccctcaatgagctcttcgcccgcttcgac
aagctggctgcggagaatcactgtttacgtattaagatcctgggagattgttattactgt
gtctcagggctgcctgaagccagggctgaccacgcccactgctgcgtggagatgggcatg
gacatgatcgaggccatctcgctggtccgggaggtgacaggtgtgaacgtgaacatgcgt
gtgggaattcacagcgggagagtgcactgcggtgtcctcggcctcaggaagtggcagttc
gatgtctggtctaacgatgtcacactggccaaccacatggaggctggaggcaaggcggga
cgcatccacatcaccaaggccacactcaactacttgaatggtgactacgaggtggagcca
ggctgtgggggcgagcgcaacgcctacctcaaggagcacagtatcgagacctttctcatc
ctgcgctgcacccagaagcggaaagaagaaaaggccatgattgccaagatgaaccgccag
agaaccaactccatcgggcacaacccgcctcactggggggccgagcgccccttctataac
cagctgggtggcaaccaggtgtccaaggagatgaagcggatgggctttgaagaccccaag
gacaagaatgcccaggaaagttcgaaccctgaggatgaagtggatgaatttctgggccgt
gccattgatgccaggagcatcgacaggctgcgatccgaacatgttcgcaagttcctcttg
accttcagggagcctgacttagagaagaagtactccaagcaagtggatgaccgattcggt
gcctacgtggcctgtgcctcgcttgtcttcctcttcatctgctttgtccagatcaccgtt
gtgccccactccgtgttcatgttgagtttctacctgacctgtttcctgctgctgaccttg
gtggtgtttgtgtccgtgatctattcttgcgtgaagctcttcccggccccgctgcagacc
ctctccaggaagattgtgaggtccaagatgaacagcaccctggtgggggtgttcaccatc
accctcgtgttcctgtcggcttttgtcaacatgttcacgtgcaactccaaggacctgttt
ggctgcctgggggacgagcacaacatcagtgccagtcaggtcaacgcgtgccacgtggtg
gagtcggccgtcaactacagtctgggtgatgagcagggcttctgcggcagctcctggccc
aactgcaacttccccgagtacttcacctacagcgtgctgctcagcctgctggcctgctcc
gtgttcctgcagatcagctgcattgggaagctggtgctcatgctggccatcgagctcatc
tacgtgctcgtcgttgaggtgcccggtgtcacgctctttgacaatgccgacctcctggtc
acggccaacgccatagacttcaacaacaacgggacctcccagtgccctgagcatccgacc
aaggtggcgctgaaggtggtgacgcccgtcatcatctccgtcttcgtgctggccctgtac
ctgcatgcccagcaggtggagtccactgcccgcctcgacttcctctggaaacttcaggcc
acagaggagaaggaggagatggaggagctgcaggcctacaaccggcggctgctgcacaat
attctgcccaaggacgtggccgcacacttcctggcccgcgaacggcgcaacgacgagctc
tactatcagtcgtgcgagtgcgtggccgtcatgttcgcctccatcgccaacttctccgag
ttctacgtggaactggaggccaacaacgagggcgtcgagtgcctgcggctgctcaacgag
atcatcgcagactttgacgagatcattagtgaggaccggttcaggcagctggaaaagatc
aagaccatcggcagcacctacatggccgcctcgggcctcaatgactccacctacgacaag
gtgggcaagacccacatcaaagccctggccgacttcgccatgaagttgatggaccaaatg
aagtacatcaacgagcactccttcaacaacttccagatgaagatcgggctcaatattggc
cccgtggtggcaggcgtgatcggagcccgcaagcctcagtacgacatctggggcaatacg
gtgaacgtggccagccgcatggacagcaccggtgtgcccgaccgcatccaggtcaccaca
gacatgtaccaggtgctggccgccaacacgtaccagctggagtgccggggtgtggtcaag
gtcaagggcaaaggcgagatgatgacctacttcctcaacggagggcccccgcccagttag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (55)   
   KEGG PATHWAY (55)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (5)   
   Pfam (5)   
All databases (80)   

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