KEGG   Oryctolagus cuniculus (rabbit): 100347269
Entry
100347269         CDS       T03373                                 
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X2
  KO
K10605  breast cancer type 1 susceptibility protein [EC:2.3.2.27]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu01524  Platinum drug resistance
ocu03440  Homologous recombination
ocu03460  Fanconi anemia pathway
ocu04120  Ubiquitin mediated proteolysis
ocu04151  PI3K-Akt signaling pathway
ocu05206  MicroRNAs in cancer
ocu05224  Breast cancer
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    100347269
  09124 Replication and repair
   03440 Homologous recombination
    100347269
   03460 Fanconi anemia pathway
    100347269
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    100347269
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    100347269
  09162 Cancer: specific types
   05224 Breast cancer
    100347269
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    100347269
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ocu01009]
    100347269
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:ocu04121]
    100347269
   03036 Chromosome and associated proteins [BR:ocu03036]
    100347269
   03400 DNA repair and recombination proteins [BR:ocu03400]
    100347269
Enzymes [BR:ocu01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     100347269
Protein phosphatases and associated proteins [BR:ocu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     100347269
Ubiquitin system [BR:ocu04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    100347269
  Multi subunit Ring-finger type E3
   BRCC complex
    100347269
Chromosome and associated proteins [BR:ocu03036]
 Eukaryotic type
  Centrosome formation proteins
   Centrosome duplication proteins
    Regulators of centriole replication
     100347269
DNA repair and recombination proteins [BR:ocu03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    BRCA1-core complex
     100347269
    BRCA1-A complex
     100347269
    BRCA1-B complex
     100347269
    BRCA1-C complex
     100347269
    BRCA complex
     100347269
   FA (Fanconi anemia) pathway
    Downstream FA components
     100347269
SSDB
Motif
Pfam: BRCT_assoc BRCT zf-C3HC4 zf-C3HC4_2 zf-C3HC4_4 zf-RING_2 zf-C3HC4_3 zf-RING_UBOX zf-RING_5 BRCT_2 zf-RING_6 zf-Nse zf-ANAPC11 zf-RING_10 zf-rbx1 RTT107_BRCT_5 Prok-RING_4
Other DBs
NCBI-GeneID: 100347269
NCBI-ProteinID: XP_008269770
Ensembl: ENSOCUG00000003883
UniProt: G1SKM1
Position
19:complement(41239950..41310578)
AA seq 1852 aa
MDLSGVRVEEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
CPLCKNDITKRSLQESTRFSQLVEELLKMIQAFELDTGLPFANSYDFSKKKNNSPEHQKE
DVSIIQSIGYRNRAKGLRKIEPKNPTLETSLSVQVSDLGIVRSLRTTHQIQPQNKSVYIE
LGSDSSEETVNKANYYSLGNEEFLQSTLQGANAEATLDPAKKAACVFSEKEITNIEPHQS
NNKDLTTVKKHATERHPEKYQGISISNLHVEPCGTDTHASSLQHENSSLLLTKDRMNVEK
AEFCNKSKQPGLARSQQSRWAESKETCNDRQTPSTEKKVVPNVDCLYGRKQQDKQKPSCP
ETSGDNQDVSWITVNSSIQKVNEWFSRSNEMLTPDDSLDRRSESNAKVTGALEVPKEIDG
YSGSTEKIDLLASESHNALICENKRVHSKPVENNIKDKIFGKTYHRKTSLPNLSHITEDL
TIGAFAAEPLVPCPPANKLKRKRRTSSGLQPEDFIKKVDLAVVPKTPAQINQGTDQTVDN
DQEMNITNRGNENETKGDYVQKETNANPTESLEKESSFRTKVEPISSSISNMELELNVHN
SKKPKKNRLRKKSSTRRVHALELVVNKKPSPPNHTELQIDSCTSSEEMNFDQIPVSHSRQ
VQVIEDTEPPTGARKNKPNEQISKRHASDVFPEVKLTSIPGVFTNCSSSNKLQESVNPSL
QRREIEENLDRVQVPNSALDPKDLLLCGERGLQTERSVESTSISLVPDTEYGTQDSISLL
GANTLGKAKTAANGHVSESTAIGNPKELIRDCLKDTGNDPDKCKDPLRSEVDQETSVAME
ESEFDTQYLQNTFMGSKRRSFALCSKPGDPEKECAAVCTRSNSSRKQSPEVTLEREQKEE
SQRKEEWKISHVQAADSTVGFPVVCQKEKAGDCAKWGIKEISRLCLSSQSKGSETELIAV
SKHGMSQNPYHMPPISPIKPSVKATRQVNLSGQRSEEHSVSSERAVGSESLIPSTVSTIS
QEYIRESALKGFSSSSINEGGSSANEVCSSVNEVGSSGENMQAQPGRSRAPELNAVLRLG
LMQPEVCEQSLPVSNSELPKLQRQEENEGVVQAVNRDFSSYLVPDSQEQSIGGRHASQIC
SETPDDLLDIYEIKENTSFAESGIKERSAVFSKSVQRGECSRTPSPSGHACLAQSHQREA
RKLESSEEHIPSEDEELICFQQLLFGKVTDRPSQSTRRSAVATECVSEKTEENFVSLKNS
LNDSDNEVTLSKASQEHPPSQGSECSGSLFSSQCSAVEDLNENTNSQDPFLMFDSPSKQM
RHQSESQQDTSDKELASDDEDNLQGQNVDANLGAAASGCESEASLSGVHSGLSSQSEILT
TQQRDTMQDNLLKLQEEMAQLEAVLEQNGSQPSYRPPSPLPDPCASEDPLNLQQNTSEKG
VLTSEKTSEYPISRNPKSLSVDKFRESPHHSNSKNKEPGAGRTSPSESQLFGNRWYTHSH
SSALRNKSCPPQEESVKEVGLEQRQLEDSEPQDSVSESYLPTQDTEGTPYLESGISLFSD
PESAPAEDRAPGPAPVCSSPDSRSTLKLPQFQVAESVQSPANDSAGCSSKEESLSLDKPE
SISSTERINKGISMVVSGLTPKEFMLVHKFARKYHITLTNVITEETTHVIMKTDAEFVCE
RTLKYFLGIAGGKWVVSYFWVTQSIKERKILDEHDFEVRGDVVNGRNHQGPKRARESQDR
KIFRGLEICCYGPYTNMPTDQLEWMVQLCGASVVRELSSFTRGTGVHPIVVVQPDAWTED
GGFHGIGQMCAASVVSREWVLDSIALYQCQELDPYLIPQSPAAAAEHSRPRV
NT seq 5559 nt   +upstreamnt  +downstreamnt
atggatttgtctggagttcgtgttgaagaagtacaaaatgtccttaatgctatgcagaaa
atcttagagtgtccaatctgtctggaattgattaaagaacctgtttctacaaaatgtgac
catatattttgcaaattttgtatgctgaagcttctcaaccagaagaaagggccctcacaa
tgtcctttgtgtaagaatgatataaccaaaagaagccttcaagagagtacaagatttagt
caacttgttgaagagctattgaaaatgattcaggcttttgagcttgacacaggattgccc
tttgcaaacagttatgacttttcaaaaaagaaaaacaactctcctgaacatcaaaaggag
gacgtttctatcattcaaagtataggctaccgaaaccgtgccaaagggcttcgaaagatt
gaacccaaaaatcctacgttggaaaccagtcttagtgtccaagtctctgaccttggaatt
gtgagatctctgaggacaacgcatcagatacaacctcaaaataagtctgtctacattgaa
ttgggatctgattcttctgaagaaacagttaataaggcgaattattacagtctgggaaat
gaagaatttttacaaagcactcttcaaggagccaatgctgaagccactttggatcctgca
aaaaaggctgcttgtgtgttttctgagaaggaaataacaaatattgaacctcatcaatcc
aataataaagatttgaccactgttaagaagcatgcaactgagaggcatccagaaaagtat
cagggtatttctatttcaaacttgcatgtggagccatgtggcacagatactcatgccagc
tcattacagcatgagaacagcagtttattactcactaaagacagaatgaatgtagaaaag
gctgaattctgtaataagagcaagcagcctggcttagcaagaagccaacagagcagatgg
gccgaaagtaaggaaacatgtaatgataggcagactcccagcacagagaaaaaggtagtt
ccgaatgttgattgcctgtatgggagaaaacaacaggataagcagaaaccttcgtgccct
gagacctctggagataaccaagatgtttcttggataacagtaaatagcagcattcagaaa
gttaacgagtggttctccagaagtaatgaaatgttaactcctgatgattcacttgaccgg
cggtctgaatcaaatgccaaagtgactggtgcattagaagttccaaaggagatagatgga
tattctggttctacagagaaaatagacttactggccagtgagtcccataatgctttaata
tgtgaaaataaaagagtccattccaaaccagtagagaataatatcaaagataaaatattc
gggaaaacctaccacaggaagacaagcctccctaacttgagccacataactgaagatcta
actataggagcgtttgctgcggaaccactggtaccgtgtccacccgcaaataaattaaaa
cgtaaaagaagaacttcttcaggccttcaacctgaagattttatcaagaaggtagatttg
gcagttgttccaaaaactcctgcacagataaatcagggaactgatcaaacagtggacaat
gatcaggagatgaatattactaatcgtggtaatgagaatgaaacaaaaggtgattatgtt
cagaaagagacaaatgctaacccaacagaatccctggaaaaagaatcttccttcagaact
aaagttgaacctataagcagcagtataagcaatatggaactagaattaaatgtccataat
tcaaaaaaacccaagaagaataggctgaggaagaagtcctctaccaggcgtgttcatgca
cttgaactagtagtcaataagaaaccgagcccacctaatcatactgaactacaaattgat
agttgtactagcagtgaagaaatgaatttcgaccaaataccagtcagtcacagcagacag
gttcaagtcatagaagatacagaacctccaactggagctaggaagaacaagccaaatgaa
caaataagtaaaagacatgccagtgatgttttcccagaagtaaaattaacaagcatacct
ggtgtttttactaactgttcaagttctaataaacttcaagaatctgtcaatcctagcctt
caaagaagggaaatagaagagaaccttgacagagttcaagtgcctaatagtgccctagac
cccaaagatctcctgttatgtggagaaaggggcttgcaaactgaaaggtctgtggagagt
accagtatttcactggtacctgatactgaatatggtactcaggacagcatctcattactg
ggcgctaacacccttggaaaggcaaaaacagcagcaaatggacatgtgagtgagagcaca
gcaattggaaatcccaaggaacttatccgtgattgtttgaaagatactggaaatgacccg
gacaaatgtaaggatccattgagaagtgaagttgaccaagagacaagcgtagcaatggaa
gagagtgagtttgatactcagtatttacagaatacattcatgggttccaagcgtcgttca
tttgctctgtgttcaaaaccaggagatccagaaaaggaatgtgcagcagtctgtacccgc
tccaactcctcaaggaaacaaagtccagaagtcactcttgaacgtgaacaaaaagaagaa
agtcagagaaaggaagagtggaaaatcagtcatgtccaggcagccgatagcactgtgggc
tttcctgtggtgtgtcagaaagagaaggcaggtgattgtgccaaatggggcattaaagag
atctctaggctttgtctgtcatctcagtccaaaggcagtgaaactgagctcattgctgta
agtaaacatggaatgtcacaaaacccatatcatatgccaccaatttctcccatcaagcca
tctgttaaagccacacgtcaggtaaacctgtcagggcaaaggtctgaggaacattccgtg
tcatctgaaagagcagtgggaagcgagagcctcattccaagcacagtgagcacaattagc
caagagtacattagagaaagtgctttgaaaggattcagctcgagcagtattaatgaaggg
ggctctagtgctaacgaagtatgctccagtgttaatgaagtaggatccagtggtgaaaac
atgcaagcacaaccaggcagaagcagagcacctgagttaaatgctgtgcttagattaggt
cttatgcagcctgaagtctgtgagcaaagtcttcctgtaagtaattctgaacttcccaaa
ctccaaaggcaagaagaaaacgaaggagtagttcaggctgtgaacagagatttctcttcg
tatctggttcctgatagccaagagcagtctataggaggtaggcatgcttctcagatttgt
tctgagacacctgatgacctgttagatatttatgaaataaaggaaaataccagctttgct
gagagcggcattaaggaaagatctgctgtgtttagtaaaagtgttcagaggggagagtgc
agtagaacccctagcccttcaggccatgcatgtttggctcagagtcaccaaagagaagct
aggaaattagagtcctcagaagagcatatacctagcgaggatgaagagcttatctgcttc
caacaattactgtttggtaaagtaactgatagaccatcccaatctactagacgtagtgct
gttgccacagagtgtgtatctgagaaaacagaggagaacttcgtgtcattgaaaaatagc
ttaaacgactctgataacgaggtgacactgtcaaaggcatcccaggagcacccccccagc
cagggatcagaatgttccggtagcttgttttcttcccagtgcagtgcagtggaagacttg
aatgaaaatacaaactcccaggatcccttcttgatgtttgattctccttccaaacaaatg
agacatcagtctgaaagccagcaagatacgagtgacaaggaattggcttcagatgatgaa
gataatctccaaggacagaatgtggatgcaaacttaggtgcagcagcatctgggtgtgag
agtgaagcaagtctgtctggagtccactcagggctgtcctctcagagcgaaatcttaacc
actcagcagagggacaccatgcaagataaccttctaaaactccaggaggaaatggctcag
ctggaagctgtgttagagcagaatgggagccagccctcttacagacccccttcccccctg
cctgacccatgtgcctcggaggacccgctaaatctacaacagaacacatcagaaaaagga
gtattaacttcagagaaaactagtgaatatcctatcagccggaatccaaaaagcctttct
gttgacaagttccgggaatctccacatcattccaacagtaaaaataaagaaccaggagca
ggaaggacttccccttctgaatcccagttgttcgggaatagatggtacacgcacagccat
tcgagcgctcttcggaacaaaagctgcccacctcaagaggagtccgttaaggaagttggt
ttggagcagcggcagctggaagactctgagccgcaagattcagtgtcagagtcttatttg
ccaacacaagatacagagggcaccccttacttggaatctggaatcagcctcttctctgac
cctgaatctgctcctgctgaggacagagcccccgggccagctcctgtgtgcagctcacca
gattcacgatctacactgaagttaccccaatttcaggttgcagaatctgtccagagtcca
gctaacgatagtgctggatgcagttccaaggaagaaagtttaagcttggataagccagaa
tcaatatcctcaacagaaaggatcaacaagggaatatccatggtggtatcaggcttgacc
ccaaaagaatttatgcttgtgcacaagtttgccagaaaataccacatcactttaactaat
gtaattactgaagagactactcatgtcattatgaaaacagatgctgaatttgtgtgtgaa
cggacactgaaatattttctggggattgcaggaggaaagtgggtagttagctatttctgg
gtgacccagtcaattaaagaaagaaagatactggatgagcatgattttgaagtcagaggt
gatgtcgtcaacggaagaaaccaccagggtccgaagcgagcgagagaatcccaggacaga
aagatcttcaggggcttagaaatctgttgctatgggccctataccaacatgcccacagat
caactggagtggatggtacagctctgtggcgcctccgtggtgagggagctttcgtcattc
acccgtggcacaggagttcacccgattgtggtcgtgcagccagatgcctggacggaggac
ggtggcttccatgggattggacagatgtgtgcggcatccgtggtgagcagagagtgggtg
ttggacagcatagccctttatcagtgccaggagctggacccctacctgataccacagagc
cccgcagcagctgctgagcacagccggccacgtgtctag

  All links  
Ontology (6)   
   KEGG BRITE (6)   
Pathway (7)   
   KEGG PATHWAY (7)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (42)   
   KEGG ORTHOLOGY (1)   
   RefGene (37)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (8)   
   RefSeq(nuc) (4)   
   GenBank (2)   
   EMBL (2)   
Protein domain (17)   
   Pfam (17)   
All databases (87)   

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