KEGG   Orcinus orca (killer whale): 101280913
Entry
101280913         CDS       T05247                                 
Symbol
TYMS
Name
(RefSeq) thymidylate synthase
  KO
K00560  thymidylate synthase [EC:2.1.1.45]
Organism
oor  Orcinus orca (killer whale)
Pathway
oor00240  Pyrimidine metabolism
oor00670  One carbon pool by folate
oor01100  Metabolic pathways
oor01232  Nucleotide metabolism
oor01523  Antifolate resistance
Module
oor_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:oor00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    101280913 (TYMS)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    101280913 (TYMS)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    101280913 (TYMS)
Enzymes [BR:oor01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     101280913 (TYMS)
SSDB
Motif
Pfam: Thymidylat_synt
Other DBs
NCBI-GeneID: 101280913
NCBI-ProteinID: XP_004273821
Position
15:52424070..52439258
AA seq 315 aa
MPAAGSELPRPMSPPAAQEQGAESRPPPPHGELQYLGQIEHILRCGFRKDDRTGTGTLSV
FGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFL
DSLGFSTRAEGDLGPVYGFQWRHFGAEYKEMDSDYSDKGVDQLQKVIDTIKTNPDDRRII
LCAWNPKDVPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIA
HITGLKPGDFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLKILRKVEKIDDFKAEDFQI
EGYNPHPTIKMEMAV
NT seq 948 nt   +upstreamnt  +downstreamnt
atgcccgccgccggctccgagctgccgcgcccgatgtcgccgcccgccgcgcaggagcag
ggcgccgagtcgcggccgccgccgccgcacggggagctgcagtacttggggcagatcgag
cacattctccgctgcggctttcggaaggatgaccgcacgggcaccggcaccctgtcggtg
ttcggcatgcaggcgcgctacagcctgagagatgaatttcctctgctgacaaccaaacgt
gttttctggaagggtgttttggaggagttgctgtggtttatcaagggatccacaaacgct
aaggagctgtcttccaagggagtgaaaatctgggatgccaatgggtcccgagacttcttg
gacagcctgggattctccaccagagcagaaggggatttaggcccagtttatggctttcag
tggaggcattttggggccgaatacaaagagatggattcagattattcagataaaggagta
gatcaactgcaaaaagtgattgacacaatcaaaaccaaccctgacgacagaagaatcatc
ctgtgtgcttggaatccaaaagatgtccctctcatggccctacccccgtgccatgccctt
tgccagttctacgtggtgaacggtgagctgtcctgccagctgtaccagaggtcaggagac
atgggcctgggtgtgcccttcaacatcgccagctacgccctgctcacctacatgatcgca
cacatcacgggcctgaagccaggtgactttgtacacactttgggagatgcacacatttac
ctgaatcacattgagccgctgaaaattcagcttcagcgagaaccaaggcctttccccaag
ctcaaaatacttcgaaaagttgagaaaattgatgacttcaaggctgaagactttcagatt
gaaggctacaatcctcacccgaccattaaaatggaaatggctgtttag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (1)   
   Pfam (1)   
All databases (29)   

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