KEGG   Orcinus orca (killer whale): 101290446
Entry
101290446         CDS       T05247                                 
Symbol
ITGA4
Name
(RefSeq) integrin alpha-4
  KO
K06483  integrin alpha 4
Organism
oor  Orcinus orca (killer whale)
Pathway
oor04151  PI3K-Akt signaling pathway
oor04510  Focal adhesion
oor04512  ECM-receptor interaction
oor04514  Cell adhesion molecules
oor04640  Hematopoietic cell lineage
oor04670  Leukocyte transendothelial migration
oor04672  Intestinal immune network for IgA production
oor04810  Regulation of actin cytoskeleton
oor04820  Cytoskeleton in muscle cells
oor05135  Yersinia infection
oor05140  Leishmaniasis
oor05165  Human papillomavirus infection
oor05410  Hypertrophic cardiomyopathy
oor05412  Arrhythmogenic right ventricular cardiomyopathy
oor05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:oor00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    101290446 (ITGA4)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    101290446 (ITGA4)
   04514 Cell adhesion molecules
    101290446 (ITGA4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101290446 (ITGA4)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    101290446 (ITGA4)
   04810 Regulation of actin cytoskeleton
    101290446 (ITGA4)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    101290446 (ITGA4)
   04670 Leukocyte transendothelial migration
    101290446 (ITGA4)
   04672 Intestinal immune network for IgA production
    101290446 (ITGA4)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    101290446 (ITGA4)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    101290446 (ITGA4)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    101290446 (ITGA4)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    101290446 (ITGA4)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    101290446 (ITGA4)
   05414 Dilated cardiomyopathy
    101290446 (ITGA4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:oor04147]
    101290446 (ITGA4)
   04515 Cell adhesion molecules [BR:oor04515]
    101290446 (ITGA4)
   04090 CD molecules [BR:oor04090]
    101290446 (ITGA4)
Exosome [BR:oor04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   101290446 (ITGA4)
  Exosomal proteins of other cancer cells
   101290446 (ITGA4)
Cell adhesion molecules [BR:oor04515]
 Integrins
  Integrin alpha subunits
   101290446 (ITGA4)
CD molecules [BR:oor04090]
 Proteins
  101290446 (ITGA4)
SSDB
Motif
Pfam: Integrin_A_Ig_1 Integrin_A_Ig_3 Integrin_A_Ig_2 FG-GAP FG-GAP_3 Integrin_alpha DUF11
Other DBs
NCBI-GeneID: 101290446
NCBI-ProteinID: XP_033279571
Position
7:68807537..68890784
AA seq 1033 aa
MAAEARCGPGPRGAAVWEAVMLLLCLGVPTGRPYNVDTESAMVYKGPADTLFGYSVVLHS
HGANRWLVVGAPTASWLANTSVVNPGAIYRCRIGKNPERTCEQLQLGSPNGEPCGKTCLE
ERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYIKNENKLPTGVCYGMPSDLRTELSKRI
APCYQDYVRKFGENFASCQAGISSFYTEDLIVMGAPGSSYWTGSLFVYNITTNKYKAFLD
RHNQVKFGSYLGYSVGAGHFRSRHTTEVVGGAPQHEQIGKAYIFSIDAKELNILHEMKGK
KLGSYFGASICAVDLNADGFSDLLVGAPVQSTVREEGRVFVYINSGTGAVMNEMEIELIG
SDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDLRGAIYIYNGRADGISSAFSQRIEG
RQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRARPVVIVEASLNHPESVN
RTNFNCIENELPSVCMDLTLCFSYKGKEVPGYIVLFYNMSLDVNRKAESPSRFYFSSNGT
SDVITGSIKVSSRVANCKTHQAFMRKDVRDILTPIQIEAAYHLGHHVISKRSTEEFPPLQ
PILQQKKEKDIIAKTINFARFCAHENCSADLQVSAKIGFLRPHENKTYLAVGSMKTLMLN
VSLFNAGDDAYETTLHIRLPTGLYFIKILDLEEKQINCEVTDSSGIVKLDCRVGYIYVDH
LSRTDISFLLDASSLSRAEEDLNITVHAACENEGETGNMKRNKVTLTVPLKYEVMLTVHG
FVNPTSFVYGPKEENEPEMCMAEKMNFTFHVINTGQSMAPNISVEIMIPNSFIPQTDKLF
NILDVQTTVGECHFKNYQRKCALEQKKGTMETLKDIFKFLSKTDKRLLYCMRADPHCLTF
SCNFGKMDSGKEASVHIQLEGRPSILEMDETRALKFEIRATAFPEPNPKVIELNKDENVA
HVLLEGLHHQRPKRHFTIAIILSSLLLGLILLLLISYVMWKAGFFKRQYKSILQQENRRD
SWSYINSKSSKDD
NT seq 3102 nt   +upstreamnt  +downstreamnt
atggctgcggaagcgaggtgcgggccgggcccgcgaggggccgccgtatgggaggcggtg
atgctactgctgtgcttgggagtcccgaccgggcgcccctacaacgtggacaccgagagc
gcaatggtttacaagggccccgccgacaccctgttcggctactcggtggtgctgcacagc
cacggggcgaaccgatggctcgtagtcggggcgcccacggccagctggctcgccaacact
tcagtggtcaatcctggggcgatttacagatgcaggattggaaagaacccagagcggacg
tgcgaacagctccagctgggtagccctaatggagaaccttgtggaaagacttgtttggaa
gaaagagacaatcaatggttgggggtcacgctttccagacagcctggagaaaatggctcc
atcgtgacttgtgggcatagatggaaaaatatattttacataaagaatgaaaataagctc
cccacgggtgtttgctatggaatgccctctgatttacgaacagagctgagtaaaagaata
gctccatgctatcaagattatgtgagaaaatttggagaaaattttgcatcatgtcaagct
ggaatatctagtttttacacagaggacttaattgtgatgggagctccaggatcatcgtat
tggactggctctcttttcgtctataatataactacaaataaatacaaagcttttttagac
agacacaatcaagtgaaattcggaagttatttaggatactcagttggagccggtcacttt
cggagtcggcacactaccgaggtagttggaggagcccctcaacatgaacagattggtaaa
gcatacatattcagcattgatgcaaaagaactaaatatcttacatgaaatgaaaggtaaa
aagcttgggtcttatttcggagcttctatctgtgcggtggacctcaacgcagatggcttc
tcagacctacttgtgggagctcccgtgcagagcaccgtcagggaggaaggaagagtgttt
gtatacatcaactctggcactggagcagtcatgaacgaaatggaaatagagctcattgga
agtgacaaatatgctgcaagatttggggaatctatagtcaatcttggcgacattgataat
gatggctttgaagatgttgctattggagctccacaggaagatgacttgcgaggtgctatt
tatatttacaatggccgagcagatgggatctcgtcagccttctcacagagaattgaaggg
cgtcaaatcagcaaatcattaagtatgtttggacagtctatatctggacaaattgatgca
gataataatggatatgtagatgtagcagttggtgcttttcggtctgattctgctgtgctg
ctaagggcgagacctgtagtgattgtcgaagcttctttaaaccatcctgagtcagtaaat
agaacaaattttaactgtattgaaaatgaattgccttctgtgtgcatggatctaacactc
tgtttctcatataagggcaaagaggttccaggttatatcgttttgttttataacatgagc
ctggatgtgaaccgaaaggcagagtctccatcgagattttacttctcttccaatggaact
tctgacgtgattacaggaagcataaaagtatcaagcagagtggctaactgtaaaacacat
caagcatttatgcggaaagatgtacgggacatcctcaccccaattcagattgaagccgct
taccacctggggcatcatgtcatcagtaaacgaagtacagaggaattcccaccacttcag
ccaattcttcagcagaagaaagaaaaagacatcattgcaaaaacaataaactttgcaaga
ttttgtgcgcatgaaaactgttctgctgatttacaggtttctgcaaaaattggatttttg
aggccacatgaaaataaaacctatcttgctgttggaagtatgaagacattaatgttgaac
gtgtccttatttaatgccggagatgatgcatatgagacaactctgcatatcagactaccc
actggtctttacttcattaagattttagatctggaggagaaacaaataaactgcgaagta
acagacagctctggcatagtaaaacttgactgcagggttggttatatatatgtagatcat
ctatcaaggacagatattagctttcttctggatgccagctcactcagcagagcagaagag
gatctcaacatcacagtgcatgccgcctgtgaaaatgaaggagaaacaggcaacatgaag
cgtaacaaagtgactttaacagtacctctcaagtatgaagtcatgctaactgttcatggg
tttgtaaacccaacttcgtttgtgtatggcccaaaggaggaaaatgagcctgaaatgtgt
atggcagagaaaatgaacttcactttccacgttatcaacactggccaaagcatggctcca
aatattagtgtggaaataatgataccgaattcttttatcccccaaactgataaactgttc
aacattttggatgtccagactactgttggagaatgccattttaagaattaccaaagaaag
tgtgcattagagcagaaaaaaggcacaatggagaccctgaaagatatattcaaattttta
tcaaagactgataagaggctactgtactgcatgagagctgatccacattgtttaactttc
tcatgcaattttgggaaaatggacagtggaaaagaagccagtgttcacattcagttggag
ggtcggccatccattttagaaatggatgagactagagccctgaagtttgaaataagagca
acagcttttccagagccaaatccaaaagttattgaactaaacaaggatgagaatgttgca
catgtgctactcgaaggactacatcatcaaagacccaaacgccatttcactatagcaatt
attttaagtagcttgctacttggacttattttacttttattgatttcatatgttatgtgg
aaggctggcttcttcaaaagacagtacaagtctatcctacaacaagaaaacagaagagac
agttggagttacattaacagtaaaagcagtaaagatgattga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (15)   
   KEGG PATHWAY (15)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (40)   

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