KEGG   Odobenus rosmarus divergens (Pacific walrus): 101363371Help
Entry
101363371         CDS       T05148                                 

Gene name
INSR
Definition
(RefSeq) insulin receptor isoform X1
  KO
K04527  
insulin receptor [EC:2.7.10.1]
Organism
oro  Odobenus rosmarus divergens (Pacific walrus)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adherens junction
Insulin signaling pathway
Ovarian steroidogenesis
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:oro00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    101363371 (INSR)
   04015 Rap1 signaling pathway
    101363371 (INSR)
   04010 MAPK signaling pathway
    101363371 (INSR)
   04066 HIF-1 signaling pathway
    101363371 (INSR)
   04068 FoxO signaling pathway
    101363371 (INSR)
   04072 Phospholipase D signaling pathway
    101363371 (INSR)
   04022 cGMP - PKG signaling pathway
    101363371 (INSR)
   04151 PI3K-Akt signaling pathway
    101363371 (INSR)
   04152 AMPK signaling pathway
    101363371 (INSR)
   04150 mTOR signaling pathway
    101363371 (INSR)
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    101363371 (INSR)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    101363371 (INSR)
   04923 Regulation of lipolysis in adipocyte
    101363371 (INSR)
   04913 Ovarian Steroidogenesis
    101363371 (INSR)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    101363371 (INSR)
  Aging
   04211 Longevity regulating pathway - mammal
    101363371 (INSR)
   04213 Longevity regulating pathway - multiple species
    101363371 (INSR)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    101363371 (INSR)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    101363371 (INSR)
   04931 Insulin resistance
    101363371 (INSR)
Enzymes [BR:oro01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     101363371 (INSR)
Protein kinases [BR:oro01001]
 Receptor tyrosine kinases
  INSR family [OT]
   101363371 (INSR)
Cytokine receptors [BR:oro04050]
 Receptor tyrosine kinase
  RTK class II (Insulin receptor family)
   101363371 (INSR)
CD molecules [BR:oro04090]
 Proteins
  101363371 (INSR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Position
Unknown
AA seq 1381 aa AA seqDB search
MGAGAGRGAATAPLLVAVAALLLGATGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL
QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL
VIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE
ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSQCL
GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNRCKNSRRQG
CHQYAIHNSKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHILEGEKTIDSVTSAQELRGC
TVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL
EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE
RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ
NVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS
DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE
RQVEDSELYELDYCLKGLKLPSRTWSPPFEAEGSQKHNQSEYEESAGECCSCPKTDSQIL
KELEESSFRKTFEDYLHNVVFVPRKSSSSPGAENTRPSRKRRALGDVANVTAAAPTVPGF
PNTSTSAPTSPEEHKPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYVS
ARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVS
RRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIGP
LIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPRE
KITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKGF
TCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAA
EIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVR
WMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNC
PERVTDLMHMCWQFNPKMRPTFLEIVELLKDDLHPSFPEVSFFHSEENKAPESEELEMEF
EDMESVPLDRASHSQREEAGGRDGGSSLGLKRNYEEHIPYTHMNGGKKNGRILTLPRSNP
S
NT seq 4146 nt NT seq  +upstreamnt  +downstreamnt
atgggcgccggggctgggcggggggcggcgaccgcgccgctgctggtggcggtggccgcg
ctgctgctgggtgccacgggccacctgtacccgggagaagtgtgccctggcatggatatc
cggaacaacctcacgaggttgcatgagctggccaactgctcggtcattgaaggacatttg
cagatactgttgatgttcaaaacgaggcccgaggatttccgagacctcagtttccccaaa
ctcatcatgatcactgattacttgctgctcttccgggtctatgggctggagagcctgaag
gacctgttccccaacctcacggtcatccggggctcgcgtctcttcttcaactatgcgctg
gtcatcttcgagatggttcacctgaaggagcttggcctctacagcttgatgaacattacc
cggggctctgtccgcattgagaagaacaatgagctctgctacctggccaccattgactgg
tcgcgcatcctggattctgtggaggataattacattgtgctgaacaaagacgacaacgag
gagtgtggggacatttgtccaggcactgcaaagggcaagaccaactgccccgccactgtc
atcaacgggcagtttgtcgagcggtgttggacacacagccactgccagaaagtttgtccc
accatctgcaagtcacacggctgtaccgccgagggtctctgctgccacagccagtgttta
ggcaattgctccgagcccgacgaccccaccaagtgcgtggcctgtcgcaacttctacctg
gatggcaggtgcgtggagacctgcccgcccccgtactaccacttccaagactggcgctgc
gtgaacttcagcttctgccaggacctgcacaacagatgcaagaactcccggagacagggc
tgccaccagtatgccattcacaatagcaagtgtatccctgagtgcccctctggctacacg
atgaattccagcaacctgatgtgcactccatgcctgggcccctgtcccaaggtctgccac
atcctggagggcgagaaaaccattgactcggtgacgtctgcccaggagcttcgaggctgc
actgttgtcaacggaagcctcatcatcaacatccgagggggcaacaacctggcagctgag
ctggaggccaacctaggactcattgaagaaatttctgggtatctgaaaatccggagatcc
tacgctcttgtgtcactttcttttttccggaagttacggctgattcgaggagaaaccttg
gaaatcgggaactactctttctacgccttggacaaccagaacctaaggcagctctgggac
tggagcaaacacaacctcaccatcactcaggggaaactcttcttccactacaatcccaaa
ctctgcttgtcagaaattcacaagatggaggaagtttcaggaaccaaggggcgccaggag
aggaacgacattgccctgaagaccaatggggaccaggcgtcttgtgaaaatgaactcctt
aaattttcttacattcggacatcgtatgacaagatcttgctgaaatgggagccgtactgg
ccccctgacttccgagacctcctggggttcatgcttttctacaaagaggccccttaccag
aatgtgactgagttcgacgggcaggatgcgtgtggttccaacagctggacggtggtggac
attgacccacctctgcggtccaacgaccccaagtcgcagaaccacccagggtggctgatg
cggggtctcaagccctggacccagtatgccatctttgtcaagaccttggtcaccttttct
gatgaacgccgcacgtatggggccaagagtgatatcatctatgtacagacggatgccact
aacccttccgtccccctggatccaatctccgtttctaactcctcgtcccagattattctg
aagtggaagcctccctctgatcccaatggcaacatcacacactatctggttttctgggag
aggcaggtggaagacagtgagctgtatgagctggattactgcctcaaagggttgaaactg
ccatcccggacctggtctccgccgttcgaggccgagggctcccagaagcacaaccagagt
gaatacgaggagtctgccggcgaatgttgctcctgccccaagacggactctcagatcctc
aaggagctggaggagtcctcttttaggaagacctttgaggattacctgcacaatgtggtg
ttcgtccccagaaaatcctcttcaagccctggtgctgagaacactaggccatcgcggaaa
cgccgggccctcggggacgttgccaatgtgacggcagccgcgcccacggttccaggtttc
cccaacacctcgaccagcgcgcccacgagcccggaggagcacaagcccttcgagaaagtg
gtgaacaaagaatccctggtcatctctgggctgcgccacttcactggctaccggatcgag
ctgcaggcttgcaaccaagactcccccgaggagaggtgtagcgtggcggcctacgtcagc
gccaggaccatgcctgaagccaaggcagatgacattgttggccccgtgacccacgaaatc
ttcgagaacaatgtcgttcacttgatgtggcaggagccaaaggaacccaacggtctgatc
gtgctgtatgaagtgagttaccgacggtatggtgatgaggagctgcacctctgtgtctcc
cgcagacattttgctctggagcggggctgcaggctgcgcgggctgccgccagggaattac
agcgtgcgagtccgggccacctccctggcaggcaacggctcatggacagaagctacctat
ttctacgtgacagactatttagatgtcccgtcgaatattgcaaaaatcatcatcggcccc
ctcatctttgtctttctcttcagtgttgtgattggaagtatttacctgttcctgagaaag
aggcagccggatgggccactgggaccgctgtatgcgtcttcaaaccctgagtacctcagt
gccagtgatgtctttccatgttctgtgtatgtgccggacgagtgggaggtgcctcgggag
aagatcacgctcctgcgtgagctggggcagggctccttcggcatggtgtacgaaggcaac
gccagggacatcgtcaagggcgaggcagagacccgcgtggcggtgaagacagtcaacgag
tcggccagtctgcgggagaggatcgagtttctcaacgaggcctcagtcatgaagggcttc
acctgtcatcacgtggtccgcctcctgggggtggtgtccaaaggccagccaacgctggtg
gtgatggagctgatggctcacggcgacctgaagagctaccttcgctccctgcggccagag
gctgagaataaccccggccgccctccccctaccctgcaagagatgattcagatggcggcg
gagatcgccgatgggatggcctacctgaatgccaagaagtttgtgcaccgggatctcgca
gcccgaaactgcatggtcgcccacgatttcactgtcaaaattggagactttgggatgacc
agagacatctatgaaacggattactaccggaaaggaggcaagggtctgctccccgtgcgg
tggatggcaccggaatccctgaaggacggggtctttaccacttcttctgacatgtggtcc
ttcggcgtggtcctttgggaaatcaccagcttggcagaacagccttaccaaggcctgtct
aatgaacaggtgttgaaatttgtcatggatggagggtatctggatcaacccgacaattgt
ccagagagagtcactgatctgatgcatatgtgctggcagttcaatcccaagatgcggccc
accttcctagagatcgttgaactgctcaaggacgacctgcaccccagctttccagaagtt
tccttcttccacagcgaggagaacaaggcacctgagagcgaggagctggagatggagttc
gaggacatggagagtgtccccctggatcgggcctcacactctcagagggaggaggccggg
ggccgggatggagggtcctcgctgggcctaaaacggaactacgaggagcacatcccctac
acccacatgaacgggggcaagaaaaacggacggattctgactctgccgaggtcaaatcct
tcctaa

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