KEGG   Odobenus rosmarus divergens (Pacific walrus): 101367692
Entry
101367692         CDS       T05148                                 
Symbol
MTHFR
Name
(RefSeq) methylenetetrahydrofolate reductase isoform X1
  KO
K25004  methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.53]
Organism
oro  Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro00670  One carbon pool by folate
oro01100  Metabolic pathways
oro01523  Antifolate resistance
Brite
KEGG Orthology (KO) [BR:oro00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    101367692 (MTHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    101367692 (MTHFR)
Enzymes [BR:oro01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.53  methylenetetrahydrofolate reductase (NADPH)
     101367692 (MTHFR)
SSDB
Motif
Pfam: MTHFR
Other DBs
NCBI-GeneID: 101367692
NCBI-ProteinID: XP_004411212
UniProt: A0A2U3WPW0
Position
Unknown
AA seq 695 aa
MDHPTPKVLPARPRGPSLGMWALETGRVRFSVPPSISRNPAMVNEPRGDGGPPPRSEGSS
SGSESSKESSRCSTPGLDPERRDRLREKMRRRMESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCCQSQEQITG
YLHKAKRLGLKNILALRGDPVGDQWEEEEGGFSYAADLVRHIRSEFGDYFDICVAGYPKG
HPDAGSFEADLKYLKEKVSAGADFIITQLFFEADTFFHFVKACSEIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLTSGLVPGLHF
YTLNREMATTEVLKRLGMWIEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFARYLS
GEPNQHGHKVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPTPEQGAEAL
NT seq 2088 nt   +upstreamnt  +downstreamnt
atggaccatccaacacccaaggttctcccagccagaccccgcggcccctccctaggaatg
tgggctttggagaccggcagggtgaggttttcagtgccaccctccatcagcaggaacccg
gccatggtgaacgaacccagaggggatggcggcccccctccccgctcagagggcagcagc
agcggcagcgagagctccaaggagagttcaagatgttccacgcccgggctggaccccgag
cgccgcgacagactcagggagaagatgaggcggaggatggaatctggtgacaagtggttc
tccctggaattcttccctcctcggacggctgagggagctgtcaatctcatctcaaggttt
gatcggatgggggcaggtggccccctcttcatagatgtgacctggcacccagcaggggac
cccggctcagacaaggagacctcttccatgatgattgccagcaccgccgtgaactactgt
ggcctggagaccatcctgcacatgacctgctgctgtcagagccaggaacagatcacaggc
tacctgcacaaggccaagcggctgggactgaagaacatcttggcgttgaggggagacccc
gtgggtgaccagtgggaagaggaggagggaggcttcagctatgccgcggacttggtgagg
cacatccgaagtgagtttggggactactttgacatctgtgtggcaggttaccccaaaggc
caccccgacgcagggagctttgaggctgacctgaagtacttgaaggagaaggtatccgca
ggagccgacttcatcatcacccagcttttctttgaggctgacacattcttccactttgtt
aaggcttgcagcgagataggcattacctgccccatcctccccggaatctttcctattcag
ggctaccactcccttcggcagctcgtgaaactgtccaagctggaggtaccgcagcagatc
aaggacgtgattgagccaatcaaagacaatgatgctgccatccgaaactatggcattgag
caggccgtgagcctgtgccaggaacttctgaccagtggcttggtgccaggcctccatttc
tataccctcaaccgtgagatggccaccacagaggtgctgaagcgtctgggcatgtggatt
gaggaccccaggcgtcccctgccctgggctgtcagtgcccaccccaagcgccgggaggaa
gatgtacgtcccatcttctgggcctccagaccaaagagctacatctaccgcacacaggag
tgggatgagttccccaacggccgctggggcaattcctcctctccagccttcggggagctg
aaagactactacctcttctacctgaagagtaagtccccaagggaagagctactgaagatg
tggggggaggagctgaccagtgaagaaagtgtctttgaagtctttgcccgctacctctca
ggagagcccaaccaacatggtcacaaggtgacttgcctaccttggaatgacgagcccctg
gctgccgagaccagcctgatgaaggaggagctgctgcgagtgaaccggcagggcatcctc
accatcaactctcagcccaacatcaacgggaaaccatcctccgaccccgttgtgggctgg
ggccccagtgggggctatgtcttccagaaggcctacttggagttcttcacttcccgagag
acggtgggggcgcttctgcaggtgctgaagaagtatgagctccgggttaattaccacatc
gtggacgtcaagggtgaaaacatcaccaatgcccctgagctgcagcccaacgcagtcact
tggggcatcttccctgggcgagagatcatccagcctacagtggtcgatcctgtcagcttc
atgttctggaaggacgaagccttcgccctgtggattgagcagtggggcaagctgtatgag
gaggagtctccgtcccgcatgatcatccagtacatccatgacaactatttcctggtcaac
ttggtggacaatgagtttcctctggacaactgcctgtggcaggtggtggaagacacattt
gaacttctcaacaggcccacgccagagcaaggggcagaggctctatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (1)   
   Pfam (1)   
All databases (31)   

Download RDF
DBGET integrated database retrieval system