KEGG   Pteropus alecto (black flying fox): 102890778
Entry
102890778         CDS       T02993                                 
Symbol
MYLK
Name
(RefSeq) myosin light chain kinase, smooth muscle isoform X1
  KO
K00907  myosin-light-chain kinase [EC:2.7.11.18]
Organism
pale  Pteropus alecto (black flying fox)
Pathway
pale04020  Calcium signaling pathway
pale04022  cGMP-PKG signaling pathway
pale04270  Vascular smooth muscle contraction
pale04371  Apelin signaling pathway
pale04510  Focal adhesion
pale04611  Platelet activation
pale04810  Regulation of actin cytoskeleton
pale04921  Oxytocin signaling pathway
pale04971  Gastric acid secretion
Brite
KEGG Orthology (KO) [BR:pale00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    102890778 (MYLK)
   04020 Calcium signaling pathway
    102890778 (MYLK)
   04022 cGMP-PKG signaling pathway
    102890778 (MYLK)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102890778 (MYLK)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102890778 (MYLK)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102890778 (MYLK)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    102890778 (MYLK)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    102890778 (MYLK)
  09154 Digestive system
   04971 Gastric acid secretion
    102890778 (MYLK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pale01001]
    102890778 (MYLK)
Enzymes [BR:pale01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.18  myosin-light-chain kinase
     102890778 (MYLK)
Protein kinases [BR:pale01001]
 Serine/threonine kinases: CAMK group
  MLCK family
   102890778 (MYLK)
SSDB
Motif
Pfam: I-set Ig_3 ig Ig_2 Pkinase 23ISL V-set PK_Tyr_Ser-Thr C2-set_2 fn3 Ig_4 Invasin_D3 Kinase-like Kdo Egh16-like DUF5898 AvrM_N
Other DBs
NCBI-GeneID: 102890778
NCBI-ProteinID: XP_015451445
UniProt: L5L3U3
Position
Unknown
AA seq 1985 aa
MGDVKLASSTHVSKTSFSMDPSRAGSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP
EPQVMWHRNGQPITSGGRFRLDCGIRGSFSLVIHSVHEEDKGKYTCEATNGSGARQVTVE
LTVEGGFVKKHGQPVSKTLGERFLSPAVETRPSIWGECPPKFATKLGRAVVKEGQMGRFS
CKITGRPQPQVTWLKGDVPLQPSARVSMSEKNGMQVLEIHEVNQDDLGVYTCMVVNGSGK
ASMSAELSIQGLDNANRSFVRGTKAANSDIRKEVTNGIAQEPKMDSLETIAESKNCSSTQ
RGGSPTWATSTQPQPLRESKLDLFEDSSRKALRTPVLQKTSSTITLQATKVQPEPRAPVS
GPFSPGEKREKPAAPPPATLPTRQSGLRSQEVVSKVATRKIPMESQRDSTFPKFESKPQS
QEVREDQTVKFRCEVSGIPKPQVTWFLEGAPVRRREGTIEIYEDGGSHYLCLLRARARDS
GNYSCIASNVRGQVSCDWTLLVKRLARMEVAPSFSSVLKDCSVIEGQDFVLQCSVLGTPA
PQITWLLNEQPIQYAHSTCAAGMAELHIQDALPEDDGIYTCLAENTLGQVSCSARVTVHE
KKSDGKSEYFLPTAPGKPVAPLFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGTE
IQESEDFHFEQRGTRHSLCIQEVFPEDTGTYTCEAWNSAGAVRTQAVLTVQEPQDGTQPW
FISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALSKDTGHFEVLQNEDVFTLVLK
NVQPWHAGQYEILLKNRVGECSCQVSLMLQSSPARVTLWGREPASCEGLCGRGVVADGGG
GDCYGTLRPGWPARGQGWPEEEEGEGVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLG
KKVSTKTVSEEDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT
PKTPVPEKVPPPKPATPDFRSVLGSKKKLPTENGSNNAEALNAKAAESLKAVGNTQPSGS
LKPVGNAKPAETPKPVGNTKPAETLKPVGNAKPAEISKLVGNAKPAESVKPVGNAKPAES
QKPVGNTKPAEILKPVGNAKPSETPKPVGNAKPAETPKPVGNAKPEETPKPAEKELKKEV
KNDVNYKRGLSGATDNEKKSESQGTAPTFKEKLRDVHVAEGEKLLLQCQVSSDPPATITW
TLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCLAKNGAGQAECSCQVTVDAAP
ASENAKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRA
GESVELFSKVAGTQPITCTWMKFRKQIQESEHIKVENSESGSKLTILAARQEHCGCYTLL
VENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSVEIW
DSVDKMWKELATCRSTSFNVQDLLPDREYKFRVCAINVYGTSEPSQESELTAVGEKPEEP
KDEVEVSDDDEKEPEVDYRTVTVNTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTGKIWA
GKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEDKANIVMVLEIVSGGELFERII
DEDFELTERECIKYMKQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARR
LENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLA
NVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKL
SKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEGD
VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE
SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE
EEEEE
NT seq 5958 nt   +upstreamnt  +downstreamnt
atgggggatgtgaagctggcttcctcgacacacgtttctaaaacctccttcagtatggat
ccctcgagagctggctccatgcccctgaccgaggccccggctttcattttgccccctagg
aacctctgcatcaaagaaggagccactgccaagtttgaagggagggtccggggataccca
gagccccaagtgatgtggcacagaaatgggcaacccatcaccagtggaggccgcttccgg
ctggattgtggtatccgagggagtttcagccttgtgattcattctgtccatgaggaagac
aaaggaaagtatacctgcgaagccaccaatggtagtggtgcccgccaggtgacagtggag
ttgacagtagaagggggctttgtgaagaagcatggtcaacctgtttccaaaaccttgggg
gaaagattcttatcccctgcagtggagacccgtcctagcatctggggagagtgcccccca
aagtttgctaccaagctgggtcgagctgtggtcaaagaaggacagatgggacgattctcc
tgcaagatcactggccggccccaaccacaggtcacctggctcaagggagatgttcccctg
cagccaagtgcccgtgtgtccatgtctgagaagaatgggatgcaagttctggaaatccat
gaggtcaaccaagacgatttgggggtgtacacgtgcatggtggtgaacgggtcagggaag
gcctccatgtcagctgagctttccatccaaggtttggacaatgccaataggtcgtttgtg
aggggaacaaaggcagccaattcagatatcagaaaggaggtgaccaacggaattgcacag
gagccaaaaatggacagcctggagactatagctgaaagtaagaactgctccagcacccag
agaggcggctccccgacctgggccacaagtacccagcctcagcccctgagggaatccaag
ctggatctgttcgaggactcatctcgaaaggccctgaggacccccgtcctgcagaagact
tccagcaccatcaccctgcaggccacaaaagtccagccggaaccaagagcaccagtctcg
gggcctttctctcctggagaaaagagggagaagccagctgctccccctccagccaccctt
cccacaaggcagtctggcctgagaagccaagaagttgtgagcaaggttgctaccaggaaa
atccccatggagagccaaagggattcaacattccccaaatttgagagcaagccccaaagc
caggaagtccgtgaggatcaaacagtcaagttcaggtgtgaggtttcagggatcccaaag
ccccaagtgacctggttcctggaaggtgctcccgtgaggagacgagaaggcaccattgag
atttatgaagatggcgggtcccattacctctgcttgctgcgagcccgggcgagagacagt
gggaactacagctgcatagcctccaatgtccgaggccaggtgtcctgtgactggaccctc
ctcgtgaaaagactggctaggatggaggtggccccctcattctccagtgtcctaaaggac
tgtagcgtcattgaaggccaggactttgtgctacaatgctctgtgctgggaaccccagca
ccccaaattacttggctgctcaatgagcagcccatccagtacgctcactctacctgcgca
gctggcatggcagagctccacatccaggatgccctgcccgaagacgatggcatctacacc
tgtctggctgagaacaccttagggcaggtgtcctgcagcgcccgggtcactgtccacgaa
aagaagagtgacgggaagagtgaatattttctgcccacagctcctggcaagcccgtcgca
cctctgttcctgcagggcctctctgatctcaaagtcatggatggaagccaggtcaccatg
acagtccaggtgtcagggaacccaccccctgaagtcatctggcttcacaatgggactgag
atccaggagtcagaggactttcacttcgaacagagaggcactcgacacagcctttgtatc
caggaggtgttcccagaggacacgggcacatacacctgtgaagcctggaatagcgccgga
gctgttcgcacccaggccgtgctcacggtgcaagagccacaggacggcacccagccctgg
ttcatcagcaagcctcgctcagtgacagcctccctgggccagagtgtcctcatctcctgt
gccatagctggtgaccccttccccactgtgcactggctccgagatggcaaggccctctcc
aaagacaccggccacttcgaagtgctacagaatgaggacgtgttcaccctggttctaaaa
aatgtgcagccctggcatgctggccagtatgagatcttgcttaagaatcgcgttggtgaa
tgcagttgccaggtgtcgctgatgctacagagcagccctgcccgagttaccctgtggggg
agggagcctgccagctgtgagggcctctgcggccgaggagttgttgccgatggtggtggt
ggtgactgctatgggaccctgaggcccggctggccagcaagagggcaaggttggccagag
gaggaggaaggtgaaggtgtgcggggggtgctgaagaggcgcgtagagacgcggcagcac
acggaggaggccatccgccagcaggaggtggagcagctggacttccgtgacctcctgggg
aagaaggtgagtaccaagaccgtgtcggaagaagacctgaaagagatcccagctgagcag
atggatttccgcgccaacttgcaacggcaagtgaagccaaagactgtgtctgaggaagaa
aggaaggtgcacagcccccagcaggttgatttccgctctgtcctggccaaaaaggggact
cccaagaccccagtgcctgagaaggtaccacctccaaaacctgccaccccagattttcgc
tcagtgctgggcagcaagaaaaaattaccaacagagaacggtagcaacaatgctgaggcc
ttgaatgccaaggcggcagaaagtctcaaggccgtgggcaatacccagccttcagggtcc
ttgaaacctgtgggcaatgccaagcctgccgagaccccaaaaccagtgggtaacaccaag
ccagccgagaccctgaaacctgtgggcaatgccaaacctgccgagatctcaaaacttgtg
ggcaatgccaaaccggccgagtccgtgaaacctgtgggcaatgccaagcctgccgagagc
caaaaacctgtgggcaacaccaaaccggccgagatcctgaaacctgtgggcaatgccaag
ccttctgagaccccaaaacctgtgggcaacgccaaaccagccgagaccccaaaacctgtg
ggcaatgccaagccagaagagactccaaaaccagctgagaaagaactcaagaaggaggtt
aagaatgatgtgaactacaagagagggctttcaggggccacagataatgagaaaaaatca
gaaagccaagggacagccccaactttcaaggagaagctacgagatgtccatgtggcagag
ggtgagaagctgctactccagtgccaggtgtcctctgatcccccagccaccatcacctgg
acactgaatggaaaaacactcaagactaccaaattcatcatcctctcccaagaaggctca
ctctgctccgtctccatcgagaaggcactgccagaggacagaggcttatacaagtgttta
gccaagaatggcgccggccaggctgagtgctcctgccaagtcactgtggacgctgctccc
gccagtgagaatgccaaagccccagagatgaaatcccggaggcccaagagctcacttcct
cccgtgctaggaacagagagtgatgcaactgtgaaaaagaaacctgcacccaagacacct
ccgaaggcagccatgccccctcagatcatccagtttcctgaggaccaaaaggtgcgcgca
ggagagtctgtggagctgttcagtaaagtggcaggcacccagcccatcacctgcacctgg
atgaagttccgaaagcagatccaggagagcgagcacatcaaggtggagaacagcgagagc
ggcagcaagctcaccatcctggccgcacgccaggagcactgtggctgctacacactgctg
gtggagaacaagctgggcagcaggcaggctcaggtcaacctcactgtggtcgacaagcca
gaccccccagccggcacgccttgtgcctctgatatccggagctcctcactcaccctgtcc
tggtacggctcctcgtatgatgggggcagcgccgtacaatcctacagcgtcgagatctgg
gactcagtggacaagatgtggaaggaactagccacatgccgcagcacctcatttaacgtc
caggacctgctgcctgaccgagagtataaattccgtgtgtgtgcgatcaatgtgtacgga
accagtgagccgagccaggagtctgaactcacagcggtgggagagaaacctgaagagccg
aaggatgaagtggaggtatcagatgatgatgaaaaggagcccgaggtcgattaccgaacg
gtgacagtcaataccgaacaaaaggtgtctgacttctacgacatcgaagagagactagga
tctgggaaatttggacaggtttttcgacttgtagaaaagaaaactggaaaaatctgggca
ggtaaattcttcaaggcgtattctgcaaaagagaaagagaatatccggcaggagatcagc
atcatgaactgtcttcaccaccccaagctggtccagtgtgtggatgccttcgaagataag
gccaatatcgtcatggtcctagagatcgtgtcagggggtgagctgttcgagcgcatcatc
gacgaggactttgagctgacagagcgagagtgcatcaagtacatgaagcagatctcggag
ggggtggaatacatccacaagcaaggcatcgtccacctggacctcaagcccgagaacatc
atgtgcgtcaacaagacaggcaccaggatcaagctcatcgacttcggtctggccagaagg
ctggagaatgcagggtctctgaaggtcctctttggcaccccggagtttgtagcacctgaa
gtgatcaactacgagcccattggctatgccacggacatgtggagcatcggggtcatctgc
tacatcctggtcagtggactttcccccttcatgggcgacaacgacaacgaaaccttagcc
aacgttacctcagccacctgggactttgacgacgaggcattcgatgagatctccgatgat
gccaaggattttatcagcaacttgctgaagaaagatatgaaaaaccgcctggactgcacc
cagtgccttcagcatccatggctaatgaaagacaccaagaacatggaggccaagaagctc
tccaaggaccggatgaagaagtacatggcgagaaggaaatggcagaaaacgggcaatgct
gtgagagccattggaagattgtcctctatggcaatgatctcagggctcagcggcaggaaa
tcctcaacagggtcaccaaccagcccactcaacgcagaaaaactagaatctgaaggagat
gtctcccaagctttcctggaggctgtcgccgaggaaaagccccatgtaaaaccctatttc
tctaagaccattcgtgatttagaagtcgtggagggaagtgctgctagatttgactgcaag
attgaaggatacccagaccctgaggttgtctggttcaaagatgaccaatcgatcagggag
tctcgccacttccagatagactacgatgaggatgggaactgctctttaatcattagcgat
gtttgcggggatgacgatgccaagtacacctgcaaggctgtcaacagtcttggagaagcc
acctgcacagctgagctcattgtggaaaccatggaggaaggagaaggggaaggggaagag
gaagaagaggaagagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (9)   
   KEGG PATHWAY (9)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (51)   
   KEGG ORTHOLOGY (1)   
   RefGene (47)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   RefSeq(pep) (7)   
DNA sequence (7)   
   RefSeq(nuc) (7)   
Protein domain (17)   
   Pfam (17)   
All databases (97)   

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