| Entry |
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| Name |
Polyketide sugar unit biosynthesis
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| Class |
Metabolism; Metabolism of Terpenoids and Polyketides
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Pathway map
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| map00523 | Polyketide sugar unit biosynthesis |
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| Module |
| M00105 | dTDP-Sugar biosynthesis, Glc-1P => dTDP-Glc => dTPD-Rha [PATH:map00523] |
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| Reference |
PMID:11336289 |
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| Authors |
Rawlings BJ. |
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| Title |
Type I polyketide biosynthesis in bacteria (Part A--erythromycin biosynthesis). |
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| Journal |
Nat Prod Rep 18:190-227 (2001) |
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| Reference |
PMID:11476481 |
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| Authors |
Rawlings BJ. |
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| Title |
Type I polyketide biosynthesis in bacteria (part B). |
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| Journal |
Nat Prod Rep 18:231-81 (2001) |
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| Reference |
PMID:11451669 |
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| Authors |
Wohlert S, Lomovskaya N, Kulowski K, Fonstein L, Occi JL, Gewain KM, MacNeil DJ, Hutchinson CR |
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| Title |
Insights about the biosynthesis of the avermectin deoxysugar L-oleandrose through heterologous expression of Streptomyces avermitilis deoxysugar genes in Streptomyces lividans. |
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| Journal |
Chem Biol 8:681-700 (2001) |
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| Reference |
PMID:10770761 |
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| Authors |
Aguirrezabalaga I, Olano C, Allende N, Rodriguez L, Brana AF, Mendez C, Salas JA |
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| Title |
Identification and expression of genes involved in biosynthesis of L-oleandrose and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticus. |
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| Journal |
Antimicrob Agents Chemother 44:1266-75 (2000) |
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| Reference |
PMID:10658660 |
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| Authors |
Bate N, Butler AR, Smith IP, Cundliffe E |
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| Title |
The mycarose-biosynthetic genes of Streptomyces fradiae, producer of tylosin. |
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| Journal |
Microbiology 146 ( Pt 1):139-46 (2000) |
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| Reference |
PMID:11553351 |
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| Authors |
Amann S, Drager G, Rupprath C, Kirschning A, Elling L |
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| Title |
(Chemo)enzymatic synthesis of dTDP-activated 2,6-dideoxysugars as building blocks of polyketide antibiotics. |
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| Journal |
Carbohydr Res 335:23-32 (2001) |
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| Reference |
PMID:17460661 |
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| Authors |
Thibodeaux CJ, Melancon CE, Liu HW |
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| Title |
Unusual sugar biosynthesis and natural product glycodiversification. |
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| Journal |
Nature 446:1008-16 (2007) |
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| Reference |
PMID:10972798 |
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| Authors |
Volchegursky Y, Hu Z, Katz L, McDaniel R |
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| Title |
Biosynthesis of the anti-parasitic agent megalomicin: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea. |
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| Journal |
Mol Microbiol 37:752-62 (2000) |
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| Reference |
(PMID:15609849 (Article in Russian)) |
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| Authors |
Mironov VA, Sergienko OV, Nastasiak IN, Danilenko VN. |
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| Title |
Biogenesis and regulation of biosynthesis of erythromycins in Saccharopolyspora. |
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| Journal |
Applied Biochemistry and Microbiology 40(6): 531-541 (2004) |
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Related
pathway |
| map00401 | Novobiocin biosynthesis | | map00520 | Amino sugar and nucleotide sugar metabolism | | map00522 | Biosynthesis of 12-, 14- and 16-membered macrolides |
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| KO pathway |
ko00523 |
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