KEGG   PATHWAY: app00540Help
Entry
app00540                    Pathway                                

Name
Lipopolysaccharide biosynthesis - Accumulibacter phosphatis
Class
Metabolism; Glycan biosynthesis and metabolism
BRITE hierarchy
Pathway map
Lipopolysaccharide biosynthesis
app00540

All organismsOrtholog table
Module
CMP-KDO biosynthesis [PATH:app00540]
Other DBs
BSID: 
GO: 
Organism
Accumulibacter phosphatis [GN:app]
Gene
UDP-N-acetylglucosamine acyltransferase; K00677 UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129] [KO:K00677] [EC:2.3.1.129]
lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [KO:K02535] [EC:3.5.1.108]
UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; K02536 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191] [KO:K02536] [EC:2.3.1.191]
UDP-2; K03269 UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54] [KO:K03269] [EC:3.6.1.54]
lipid-A-disaccharide synthase; K00748 lipid-A-disaccharide synthase [EC:2.4.1.182] [KO:K00748] [EC:2.4.1.182]
tetraacyldisaccharide 4'-kinase; K00912 tetraacyldisaccharide 4'-kinase [EC:2.7.1.130] [KO:K00912] [EC:2.7.1.130]
2-dehydro-3-deoxyphosphooctonate aldolase; K01627 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55] [KO:K01627] [EC:2.5.1.55]
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; K03270 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45] [KO:K03270] [EC:3.1.3.45]
3-deoxy-D-manno-octulosonate cytidylyltransferase; K00979 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38] [KO:K00979] [EC:2.7.7.38]
3-deoxy-D-manno-octulosonic-acid transferase; K02527 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15] [KO:K02527] [EC:2.4.99.15 2.4.99.14 2.4.99.13 2.4.99.12]
lipid A biosynthesis acyltransferase; K02517 lipid A biosynthesis lauroyl acyltransferase [EC:2.3.1.-] [KO:K02517] [EC:2.3.1.-]
lipid A biosynthesis lauroyl acyltransferase; K02517 lipid A biosynthesis lauroyl acyltransferase [EC:2.3.1.-] [KO:K02517] [EC:2.3.1.-]
phosphoheptose isomerase; K03271 D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28] [KO:K03271] [EC:5.3.1.28]
D; K03273 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83] [KO:K03273] [EC:3.1.3.83 3.1.3.82]
ADP-L-glycero-D-manno-heptose-6-epimerase; K03274 ADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20] [KO:K03274] [EC:5.1.3.20]
lipopolysaccharide heptosyltransferase I; K02841 heptosyltransferase I [EC:2.4.-.-] [KO:K02841] [EC:2.4.-.-]
lipopolysaccharide heptosyltransferase II; K02843 heptosyltransferase II [EC:2.4.-.-] [KO:K02843] [EC:2.4.-.-]
group 1 glycosyl transferase; K02844 UDP-glucose:(heptosyl)LPS alpha-1,3-glucosyltransferase [EC:2.4.1.-] [KO:K02844] [EC:2.4.1.-]
lipopolysaccharide kinase; K02848 heptose (I) phosphotransferase [EC:2.7.1.-] [KO:K02848] [EC:2.7.1.-]
Compound
C00043  
UDP-N-acetyl-alpha-D-glucosamine
C00229  
Acyl-carrier protein
C01112  
D-Arabinose 5-phosphate
C01187  
3-Deoxy-D-manno-octulosonate
C04121  
CMP-3-deoxy-D-manno-octulosonate
C04478  
3-Deoxy-D-manno-octulosonate 8-phosphate
C04652  
UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine
C04738  
UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine
C04824  
Lipid X
C04919  
2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate
C04932  
Lipid A disaccharide
C05223  
Dodecanoyl-[acyl-carrier protein]
C05382  
Sedoheptulose 7-phosphate
C05761  
Tetradecanoyl-[acp]
C06022  
UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine
C06024  
3-Deoxy-D-manno-octulosonyl-lipid IV(A)
C06025  
Di[3-deoxy-D-manno-octulosonyl]-lipid IV(A)
C06026  
Di[3-deoxy-D-manno-octulosonyl]-lipid A
C06251  
Lauroyl-KDO2-lipid IV(A)
C06397  
ADP-D-glycero-beta-D-manno-heptose
C06398  
ADP-L-glycero-beta-D-manno-heptose
C07836  
D-glycero-beta-D-manno-Heptose 7-phosphate
C07838  
D-glycero-beta-D-manno-Heptose 1-phosphate
C11472  
D-glycero-beta-D-manno-Heptose 1,7-bisphosphate
C19877  
4-O-Phospho-alpha-Kdo-(2->6)-lipid IVA
C19878  
D-glycero-alpha-D-manno-Heptose 7-phosphate
C19879  
D-glycero-alpha-D-manno-Heptose 1,7-bisphosphate
C19880  
D-glycero-alpha-D-manno-Heptose 1-phosphate
C19881  
GDP-D-glycero-alpha-D-manno-heptose
Reference
PMID:9791168
  Authors
Heinrichs DE, Yethon JA, Whitfield C.
  Title
Molecular basis for structural diversity in the core regions of the lipopolysaccharides of Escherichia coli and Salmonella enterica.
  Journal
Mol Microbiol 30:221-32 (1998)
Reference
  Authors
Kneidinger B, Marolda C, Graninger M, Zamyatina A, McArthur F, Kosma P, Valvano MA, Messner P.
  Title
Biosynthesis pathway of ADP-L-glycero-beta-D-manno-heptose in Escherichia coli.
  Journal
J Bacteriol 184:363-9 (2002)
Reference
PMID:9587193
  Authors
Wyckoff TJ, Raetz CR, Jackman JE.
  Title
Antibacterial and anti-inflammatory agents that target endotoxin.
  Journal
Trends Microbiol 6:154-9 (1998)
Reference
PMID:9765561
  Authors
Shibayama K, Ohsuka S, Tanaka T, Arakawa Y, Ohta M.
  Title
Conserved structural regions involved in the catalytic mechanism of Escherichia coli K-12 WaaO (RfaI).
  Journal
J Bacteriol 180:5313-8 (1998)
KO pathway
 

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