KEGG   PATHWAY: ath04136
Entry
ath04136                    Pathway                                
Name
Autophagy - other - Arabidopsis thaliana (thale cress)
Description
Autophagy is a degradative pathway for the removal of cytoplasmic materials in eukaryotic cells, and is characterized by the formation of a double-membrane structure called the autophagosome, either in a housekeeping capacity or during stress and senescence. The process of autophagy could be divided into several stages: induction, vesicle nucleation, elongation and closure, and fusion and digestion. Most essential autophagic machineries are conserved throughout eukaryotes (see map04140 for animals and map04138 for fungi). This map is for other eukaryotes including plants and protists, where autophagy related genes (ATGs) play similar roles in the life cycle. However, autophagy has been relatively less studied in lower eukaryotes.
Class
Cellular Processes; Transport and catabolism
Pathway map
ath04136  Autophagy - other
ath04136

Other DBs
GO: 0006914
Organism
Arabidopsis thaliana (thale cress) [GN:ath]
Gene
AT3G08850  RAPTOR1; Regulatory-associated protein of TOR 1 [KO:K07204]
AT5G01770  RAPTOR2; regulatory-associated protein of TOR 2 (RAPTOR2) [KO:K07204]
AT1G50030  TOR; target of rapamycin [KO:K07203] [EC:2.7.11.1]
AT2G22040  LST8-2; Transducin/WD40 repeat-like superfamily protein [KO:K08266]
AT3G18140  LST8-1; Transducin/WD40 repeat-like superfamily protein [KO:K08266]
AT2G37840  Protein kinase superfamily protein [KO:K08269] [EC:2.7.11.1]
AT3G53930  Protein kinase superfamily protein [KO:K08269] [EC:2.7.11.1]
AT3G18770  Autophagy-related protein 13 [KO:K08331]
AT3G49590  ATG13; Autophagy-related protein 13 [KO:K08331]
AT5G66930  meiotically up-regulated protein [KO:K19730]
AT4G30790  autophagy-like protein [KO:K08330]
AT5G53000  TAP46; 2A phosphatase associated protein of 46 kD [KO:K17606]
AT1G10430  PP2A-2; protein phosphatase 2A-2 [KO:K04382] [EC:3.1.3.16]
AT1G59830  PP2A-1; protein phosphatase 2A-2 [KO:K04382] [EC:3.1.3.16]
AT1G69960  PP2A; serine/threonine protein phosphatase 2A [KO:K04382] [EC:3.1.3.16]
AT2G42500  PP2A-3; protein phosphatase 2A-3 [KO:K04382] [EC:3.1.3.16]
AT3G58500  PP2A-4; protein phosphatase 2A-4 [KO:K04382] [EC:3.1.3.16]
AT2G31260  APG9; autophagy 9 (APG9) [KO:K17907]
AT3G19190  ATG2; autophagy 2 [KO:K17906]
AT4G30510  ATG18B; autophagy 18 B-like protein [KO:K17908]
AT3G61710  ATG6; AUTOPHAGY 6 [KO:K08334]
AT1G60490  VPS34; vacuolar protein sorting 34 [KO:K00914] [EC:2.7.1.137]
AT4G29380  VPS15; protein kinase family protein / WD-40 repeat family protein [KO:K08333] [EC:2.7.11.1]
AT3G13970  APG12B; Ubiquitin-like superfamily protein [KO:K08336]
AT1G54210  ATG12A; Ubiquitin-like superfamily protein [KO:K08336]
AT5G17290  APG5; autophagy protein Apg5 family [KO:K08339]
AT5G50230  Transducin/WD40 repeat-like superfamily protein [KO:K17890]
AT5G45900  APG7; ThiF family protein [KO:K08337]
AT3G07525  ATG10; autophagocytosis-associated family protein [KO:K17888]
AT5G61500  ATG3; autophagy 3 (APG3) [KO:K08343]
AT2G05630  ATG8D; Ubiquitin-like superfamily protein [KO:K08341]
AT4G16520  ATG8F; Ubiquitin-like superfamily protein [KO:K08341]
AT4G04620  ATG8B; Ubiquitin-like superfamily protein [KO:K08341]
AT4G21980  APG8A; Ubiquitin-like superfamily protein [KO:K08341]
AT1G62040  ATG8C; Ubiquitin-like superfamily protein [KO:K08341]
AT2G45170  ATG8E; AUTOPHAGY 8E [KO:K08341]
AT3G60640  ATG8G; Ubiquitin-like superfamily protein [KO:K08341]
AT3G06420  ATG8H; Ubiquitin-like superfamily protein [KO:K08341]
AT3G15580  APG8H; Ubiquitin-like superfamily protein [KO:K08341]
AT2G44140  Peptidase family C54 protein [KO:K08342] [EC:3.4.22.-]
AT3G59950  Peptidase family C54 protein [KO:K08342] [EC:3.4.22.-]
Compound
C00350  Phosphatidylethanolamine
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
Reference
PMID:20962583
  Authors
Duszenko M, Ginger ML, Brennand A, Gualdron-Lopez M, Colombo MI, Coombs GH, Coppens I, Jayabalasingham B, Langsley G, de Castro SL, Menna-Barreto R, Mottram JC, Navarro M, Rigden DJ, Romano PS, Stoka V, Turk B, Michels PA
  Title
Autophagy in protists.
  Journal
Autophagy 7:127-58 (2011)
DOI:10.4161/auto.7.2.13310
Reference
PMID:21660427
  Authors
Avin-Wittenberg T, Honig A, Galili G
  Title
Variations on a theme: plant autophagy in comparison to yeast and mammals.
  Journal
Protoplasma 249:285-99 (2012)
DOI:10.1007/s00709-011-0296-z
Reference
PMID:22242963
  Authors
Liu Y, Bassham DC
  Title
Autophagy: pathways for self-eating in plant cells.
  Journal
Annu Rev Plant Biol 63:215-37 (2012)
DOI:10.1146/annurev-arplant-042811-105441
Reference
PMID:22764279
  Authors
Yoshimoto K
  Title
Beginning to understand autophagy, an intracellular self-degradation system in plants.
  Journal
Plant Cell Physiol 53:1355-65 (2012)
DOI:10.1093/pcp/pcs099
Reference
PMID:24563201
  Authors
Li F, Chung T, Vierstra RD
  Title
AUTOPHAGY-RELATED11 plays a critical role in general autophagy- and senescence-induced mitophagy in Arabidopsis.
  Journal
Plant Cell 26:788-807 (2014)
DOI:10.1105/tpc.113.120014
Reference
PMID:26598298
  Authors
Michaeli S, Galili G, Genschik P, Fernie AR, Avin-Wittenberg T
  Title
Autophagy in Plants--What's New on the Menu?
  Journal
Trends Plant Sci 21:134-44 (2016)
DOI:10.1016/j.tplants.2015.10.008
Reference
PMID:26614870
  Authors
Yang X, Bassham DC
  Title
New Insight into the Mechanism and Function of Autophagy in Plant Cells.
  Journal
Int Rev Cell Mol Biol 320:1-40 (2015)
DOI:10.1016/bs.ircmb.2015.07.005
KO pathway
ko04136   

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Genome (1)   
   KEGG GENOME (1)   
Gene (41)   
   KEGG GENES (41)   
All databases (42)   

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