KEGG   PATHWAY: bme00230
Entry
bme00230                    Pathway                                
Name
Purine metabolism - Brucella melitensis bv. 1 16M
Class
Metabolism; Nucleotide metabolism
Pathway map
bme00230  Purine metabolism
bme00230

Module
bme_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bme00230]
bme_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bme00230]
bme_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bme00230]
bme_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bme00230]
bme_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bme00230]
bme_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:bme00230]
bme_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:bme00230]
Other DBs
GO: 0006163 0042278
Organism
Brucella melitensis bv. 1 16M [GN:bme]
Gene
BMEI1886  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
BMEI0483  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
BMEI1488  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
BMEI1519  phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
BMEI1241  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BMEI1127  phosphoribosylformylglycinamidine synthase [KO:K23269] [EC:6.3.5.3]
BMEI1123  phosphoribosylformylglycinamidine synthase, purs component [KO:K23264] [EC:6.3.5.3]
BMEI1124  phosphoribosylformylglycinamidine synthase [KO:K23265] [EC:6.3.5.3 3.5.1.2]
BMEI1240  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
BMEI0295  phosphoribosylaminoimidazole carboxylase atpase subunit [KO:K01589] [EC:6.3.4.18]
BMEI0296  phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
BMEI1122  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BMEI1117  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BMEI0233  phosphoribosylaminoimidazolecarboxamide formyltransferase / imp cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BMEI0476  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BMEI1081  stationary-phase survival protein sure [KO:K03787] [EC:3.1.3.5 3.1.3.6]
BMEI0486  hypothetical cytosolic protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BMEI0082  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
BMEII0896  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
BMEI1256  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
BMEI1772  nucleoside-triphosphatase [KO:K01519] [EC:3.6.1.66]
BMEI0940  xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
BMEI1576  xanthine dehydrogenase [KO:K13481] [EC:1.17.1.4]
BMEI1575  xanthine dehydrogenase [KO:K13482] [EC:1.17.1.4]
BMEI0941  bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) [KO:K01518] [EC:3.6.1.17]
BMEII0887  gmp synthase (glutamine-hydrolyzing) [KO:K01951] [EC:6.3.5.2]
BMEI1571  guanine deaminase [KO:K01487] [EC:3.5.4.3]
BMEI1469  guanylate kinase [KO:K00942] [EC:2.7.4.8]
BMEII0930  ribonucleoside-diphosphate reductase alpha chain [KO:K00525] [EC:1.17.4.1]
BMEI0943  vitamin b12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
BMEII0929  ribonucleoside-diphosphate reductase beta chain [KO:K00526] [EC:1.17.4.1]
BMEI1090  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
BMEI1283  hypothetical cytosolic protein [KO:K06952] [EC:3.1.3.89]
BMEI1296  guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BMEI1204  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BMEII0598  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BMEI0351  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
BMEI1318  amp nucleosidase [KO:K01241] [EC:3.2.2.4]
BMEII0627  probable adenine deaminase [KO:K01486] [EC:3.5.4.2]
BMEI0316  hypothetical protein [KO:K09769] [EC:3.1.4.16]
BMEI0778  adenylate kinase [KO:K00939] [EC:2.7.4.3]
BMEI1228  adenylate kinase [KO:K00939] [EC:2.7.4.3]
BMEI0920  mazg protein [KO:K04765] [EC:3.6.1.9]
BMEI1754  sulfate adenylyltransferase / adenylylsulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
BMEI1755  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
BMEI1429  transthyretin-like protein precursor [KO:K07127] [EC:3.5.2.17]
BMEI1577  chitooligosaccharide deacetylase [KO:K16842] [EC:3.5.2.5]
BMEI1578  glyoxylate induced protein [KO:K14977] [EC:3.5.3.26]
BMEI1430  ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
BMEI0647  urease alpha subunit [KO:K01428] [EC:3.5.1.5]
BMEI1652  urease alpha subunit [KO:K01428] [EC:3.5.1.5]
BMEI0648  urease beta subunit [KO:K01429] [EC:3.5.1.5]
BMEI1653  urease beta subunit [KO:K01429] [EC:3.5.1.5]
BMEI0649  urease gamma subunit [KO:K01430] [EC:3.5.1.5]
BMEI1654  urease gamma subunit [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bme00030  Pentose phosphate pathway
bme00220  Arginine biosynthesis
bme00250  Alanine, aspartate and glutamate metabolism
bme00260  Glycine, serine and threonine metabolism
bme00340  Histidine metabolism
bme00630  Glyoxylate and dicarboxylate metabolism
bme00730  Thiamine metabolism
bme00740  Riboflavin metabolism
bme00790  Folate biosynthesis
KO pathway
ko00230   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (55)   
   KEGG GENES (55)   
All databases (56)   

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