KEGG   PATHWAY: bmt00290Help
Entry
bmt00290                    Pathway                                

Name
Valine, leucine and isoleucine biosynthesis - Brucella suis ATCC 23445
Class
Metabolism; Amino acid metabolism
BRITE hierarchy
Pathway map
Valine, leucine and isoleucine biosynthesis
bmt00290

All organismsOrtholog table
Module
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:bmt00290]
Other DBs
Organism
Brucella suis ATCC 23445 [GN:bmt]
Gene
ilvA; threonine dehydratase biosynthetic [KO:K01754] [EC:4.3.1.19]
leuC; isopropylmalate isomerase large subunit [KO:K01703] [EC:4.2.1.35 4.2.1.33]
leuD; isopropylmalate isomerase small subunit [KO:K01704] [EC:4.2.1.35 4.2.1.33]
leuB; 3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
ilvB; acetolactate synthase 3 catalytic subunit [KO:K01652] [EC:2.2.1.6]
ilvH; acetolactate synthase 3 regulatory subunit [KO:K01653] [EC:2.2.1.6]
ilvC; ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
ilvD; dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
dihydroxy-acid dehydratase; K01687 dihydroxy-acid dehydratase [EC:4.2.1.9] [KO:K01687] [EC:4.2.1.9]
leuA; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
putative alpha-isopropylmalate/homocitrate synthase family transferase; K01649 2-isopropylmalate synthase [EC:2.3.3.13] [KO:K01649] [EC:2.3.3.13]
Compound
C00022  
Pyruvate
C00024  
Acetyl-CoA
C00109  
2-Oxobutanoate
C00123  
L-Leucine
C00141  
3-Methyl-2-oxobutanoic acid
C00183  
L-Valine
C00188  
L-Threonine
C00233  
4-Methyl-2-oxopentanoate
C00407  
L-Isoleucine
C00671  
(S)-3-Methyl-2-oxopentanoic acid
C02226  
2-Methylmaleate
C02504  
alpha-Isopropylmalate
C02612  
(R)-2-Methylmalate
C02631  
2-Isopropylmaleate
C04181  
3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  
(2S)-2-Isopropyl-3-oxosuccinate
C04272  
(R)-2,3-Dihydroxy-3-methylbutanoate
C04411  
(2R,3S)-3-Isopropylmalate
C06006  
(S)-2-Aceto-2-hydroxybutanoate
C06007  
(R)-2,3-Dihydroxy-3-methylpentanoate
C06010  
(S)-2-Acetolactate
C06032  
D-erythro-3-Methylmalate
C14463  
(R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
KO pathway
 

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