KEGG   PATHWAY: bmy00190Help
Entry
bmy00190                    Pathway                                

Name
Oxidative phosphorylation - Brugia malayi (filaria)
Class
Metabolism; Energy metabolism
BRITE hierarchy
Pathway map
bmy00190  Oxidative phosphorylation
bmy00190

Ortholog table
Module
bmy_M00142  NADH:ubiquinone oxidoreductase, mitochondria [PATH:bmy00190]
bmy_M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:bmy00190]
bmy_M00148  Succinate dehydrogenase (ubiquinone) [PATH:bmy00190]
bmy_M00151  Cytochrome bc1 complex respiratory unit [PATH:bmy00190]
Organism
Brugia malayi (filaria) [GN:bmy]
Gene
ND1  NADH dehydrogenase subunit 1 [KO:K03878] [EC:1.6.5.3]
ND2  NADH dehydrogenase subunit 2 [KO:K03879] [EC:1.6.5.3]
ND3  NADH dehydrogenase subunit 3 [KO:K03880] [EC:1.6.5.3]
ND4  NADH dehydrogenase subunit 4 [KO:K03881] [EC:1.6.5.3]
ND4L  NADH dehydrogenase subunit 4L [KO:K03882] [EC:1.6.5.3]
ND5  NADH dehydrogenase subunit 5 [KO:K03883] [EC:1.6.5.3]
ND6  NADH dehydrogenase subunit 6 [KO:K03884] [EC:1.6.5.3]
Bm1_52130  NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial precursor [KO:K03934] [EC:1.6.99.3 1.6.5.3]
Bm1_25145  NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial [KO:K03935] [EC:1.6.99.3 1.6.5.3]
Bm1_38090  Probable NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrialprecursor [KO:K03935] [EC:1.6.99.3 1.6.5.3]
Bm1_07360  NADH-ubiquinone oxidoreductase 30 kDa subunit, mitochondrial precursor [KO:K03936] [EC:1.6.99.3 1.6.5.3]
Bm1_55425  ETC complex I subunit conserved region family protein [KO:K03937]
Bm1_49180  NADH-ubiquinone oxidoreductase 15 kDa subunit [KO:K03938]
Bm1_12235  Probable NADH-ubiquinone oxidoreductase 13 kDa-A subunit,mitochondrial precursor [KO:K03939]
Bm1_48645  Probable NADH-ubiquinone oxidoreductase 20 kDa subunit, mitochondrialprecursor [KO:K03940] [EC:1.6.99.3 1.6.5.3]
Bm1_20770  NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial precursor [KO:K03941] [EC:1.6.99.3 1.6.5.3]
Bm1_14150  NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial precursor [KO:K03942] [EC:1.6.99.3 1.6.5.3]
Bm1_20470  NADH-ubiquinone oxidoreductase 24 kDa subunit, mitochondrial precursor [KO:K03943] [EC:1.6.99.3 1.6.5.3]
Bm1_09245  RH49308p [KO:K03945]
Bm1_56520  NADH-ubiquinone oxidoreductase B8 subunit [KO:K03946]
Bm1_14410  NADH-ubiquinone oxidoreductase 17.3 kDa subunit, putative [KO:K03949]
Bm1_35470  hypothetical protein [KO:K03951]
Bm1_45585  NADH-ubiquinone oxidoreductase 19 kDa subunit [KO:K03952]
Bm1_11415  NADH-ubiquinone oxidoreductase 39 kDa subunit, mitochondrial precursor [KO:K03953]
Bm1_46305  Deoxynucleoside kinase family protein [KO:K03954]
Bm1_19045  acyl carrier protein, mitochondrial precursor, putative [KO:K03955]
Bm1_16695  Phosphopantetheine attachment site family protein [KO:K03955]
Bm1_36520  NADH-ubiquinone oxidoreductase subunit B17.2 [KO:K11352]
Bm1_18845  GRIM-19 protein [KO:K11353]
Bm1_04880  NADH-ubiquinone oxidoreductase AGGG subunit homolog, mitochondrialprecursor [KO:K03958]
Bm1_55690  NADH-ubiquinone oxidoreductase B12 subunit [KO:K03959]
Bm1_18685  hypothetical protein [KO:K03960]
Bm1_15245  RH17657p [KO:K03961]
Bm1_16245  symbol [KO:K03962]
Bm1_55795  Probable NADH-ubiquinone oxidoreductase B18 subunit, putative [KO:K03963]
Bm1_44000  NADH-ubiquinone oxidoreductase ASHI subunit, mitochondrial precursor [KO:K03964]
Bm1_09670  NADH-ubiquinone oxidoreductase B22 subunit [KO:K03965]
Bm1_31215  hypothetical protein [KO:K03966]
Bm1_39265  GH05862p [KO:K11351]
Bm1_53755  NADH-ubiquinone oxidoreductase subunit B14.5b [KO:K03968]
Bm1_17330  succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial [KO:K00234] [EC:1.3.5.1]
Bm1_17690  succinate dehydrogenase [ubiquinone] iron-sulfur protein, mitochondrial [KO:K00235] [EC:1.3.5.1]
Bm1_30090  Succinate dehydrogenase cytochrome b560 subunit, mitochondrialprecursor [KO:K00236]
Bm1_35660  Succinate dehydrogenase [KO:K00237]
Bm1_46150  ubiquinol-cytochrome c reductase, iron-sulfur subunit family protein [KO:K00411] [EC:1.10.2.2]
CYTB  cytochrome b [KO:K00412]
Bm1_26800  Cytochrome C1 family protein [KO:K00413]
Bm1_37260  Peptidase M16 inactive domain containing protein [KO:K00415]
Bm1_14750  Ubiquinol-cytochrome C reductase hinge protein [KO:K00416]
Bm1_23555  UcrQ family protein [KO:K00418]
Bm1_47450  hypothetical protein [KO:K00419]
Bm1_46095  hypothetical protein [KO:K00420]
Bm1_37295  protoheme IX farnesyltransferase family protein [KO:K02257] [EC:2.5.1.141]
COX3  cytochrome c oxidase subunit III [KO:K02262]
COX1  cytochrome c oxidase subunit I [KO:K02256] [EC:1.9.3.1]
COX2  cytochrome c oxidase subunit II [KO:K02261]
Bm1_03920  Cytochrome c oxidase subunit IV family protein [KO:K02263]
Bm1_11490  Cytochrome c oxidase polypeptide Va, mitochondrial precursor [KO:K02264]
Bm1_29430  Cytochrome c oxidase polypeptide Vb, mitochondrial precursor [KO:K02265]
Bm1_25100  Cytochrome c oxidase subunit VIa family protein [KO:K02266]
Bm1_38460  cytochrome oxidase c subunit VIb family protein [KO:K02267]
Bm1_49700  Cytochrome c oxidase assembly protein CtaG / Cox11 containing protein [KO:K02258]
Bm1_07665  Cytochrome oxidase assembly protein [KO:K02259]
Bm1_46550  cytochrome c oxidase copper chaperone [KO:K02260]
Bm1_47570  ATP synthase alpha chain, mitochondrial precursor, putative [KO:K02132]
Bm1_45960  ATP synthase beta chain, mitochondrial precursor, putative [KO:K02133] [EC:3.6.3.14]
Bm1_13335  ATP synthase gamma chain, mitochondrial precursor, putative [KO:K02136]
Bm1_57260  ATP synthase delta chain, mitochondrial precursor, putative [KO:K02134]
Bm1_00120  ATP synthase epsilon chain, mitochondrial [KO:K02135]
Bm1_03855  ATP synthase F1, delta subunit family protein [KO:K02137]
Bm1_03845  hypothetical protein [KO:K02137]
Bm1_24615  ATP synthase B chain, mitochondrial precursor [KO:K02127]
Bm1_47320  ATP synthase lipid-binding protein, mitochondrial precursor [KO:K02128]
Bm1_16555  hypothetical protein [KO:K02138]
Bm1_55895  ATP synthase e chain, mitochondrial [KO:K02129]
Bm1_24580  ATP synthase e chain, mitochondrial [KO:K02129]
Bm1_23080  ATP synthase f chain, mitochondrial [KO:K02130]
Bm1_38880  Mitochondrial ATP synthase g subunit family protein [KO:K02140]
Bm1_14330  Mitochondrial ATP synthase coupling factor 6 family protein [KO:K02131]
Bm1_50960  vacuolar ATP synthase catalytic subunit A, osteoclast isoform [KO:K02145] [EC:3.6.3.14]
Bm1_12010  vacuolar ATP synthase subunit B [KO:K02147]
Bm1_39100  V-ATPase subunit C family protein [KO:K02148]
Bm1_13590  vacuolar ATP synthase subunit D [KO:K02149]
Bm1_53000  Vacuolar h atpase protein 8 [KO:K02150]
Bm1_47090  Vacuolar ATP synthase subunit F [KO:K02151]
Bm1_12135  vacuolar ATP synthase subunit G [KO:K02152]
Bm1_46445  vacuolar proton pump [KO:K02154]
Bm1_31340  vacuolar proton pump [KO:K02154]
Bm1_44370  Vacuolar ATP synthase 16 kDa proteolipid subunit 1, putative [KO:K02155]
Bm1_44375  Vacuolar ATP synthase 16 kDa proteolipid subunit, putative [KO:K02155]
Bm1_43140  Vacuolar ATP synthase 21 kDa proteolipid subunit, putative [KO:K03661]
Bm1_48215  Vacuolar h atpase protein 16 [KO:K02146]
Bm1_17810  vacuolar ATP synthase subunit H [KO:K02153]
Bm1_36575  hypothetical protein [KO:K03662]
Bm1_16955  inorganic pyrophosphatase [KO:K01507] [EC:3.6.1.1]
Compound
C00001  H2O
C00002  ATP
C00003  NAD+
C00004  NADH
C00007  Oxygen
C00008  ADP
C00009  Orthophosphate
C00013  Diphosphate
C00042  Succinate
C00061  FMN
C00080  H+
C00122  Fumarate
C00390  Ubiquinol
C00399  Ubiquinone
C00524  Cytochrome c
C00536  Triphosphate
Reference
  Authors
Sazanov LA, Hinchliffe P.
  Title
Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus.
  Journal
Science 311:1430-6 (2006)
DOI:10.1126/science.1123809
Reference
  Authors
Hinchliffe P, Carroll J, Sazanov LA.
  Title
Identification of a novel subunit of respiratory complex I from Thermus thermophilus.
  Journal
Biochemistry 45:4413-20 (2006)
DOI:10.1021/bi0600998
KO pathway
ko00190   

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