KEGG   PATHWAY: bmy00190Help
Entry
bmy00190                    Pathway                                

Name
Oxidative phosphorylation - Brugia malayi (filaria)
Class
Metabolism; Energy metabolism
BRITE hierarchy
Pathway map
Oxidative phosphorylation
bmy00190

All organismsOrtholog table
Module
NADH:ubiquinone oxidoreductase, mitochondria [PATH:bmy00190]
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:bmy00190]
Succinate dehydrogenase (ubiquinone) [PATH:bmy00190]
Cytochrome bc1 complex respiratory unit [PATH:bmy00190]
Organism
Brugia malayi (filaria) [GN:bmy]
Gene
ND1  
NADH dehydrogenase subunit 1; K03878 NADH-ubiquinone oxidoreductase chain 1 [EC:1.6.5.3] [KO:K03878] [EC:1.6.5.3]
ND2  
NADH dehydrogenase subunit 2; K03879 NADH-ubiquinone oxidoreductase chain 2 [EC:1.6.5.3] [KO:K03879] [EC:1.6.5.3]
ND3  
NADH dehydrogenase subunit 3; K03880 NADH-ubiquinone oxidoreductase chain 3 [EC:1.6.5.3] [KO:K03880] [EC:1.6.5.3]
ND4  
NADH dehydrogenase subunit 4; K03881 NADH-ubiquinone oxidoreductase chain 4 [EC:1.6.5.3] [KO:K03881] [EC:1.6.5.3]
ND4L  
NADH dehydrogenase subunit 4L; K03882 NADH-ubiquinone oxidoreductase chain 4L [EC:1.6.5.3] [KO:K03882] [EC:1.6.5.3]
ND5  
NADH dehydrogenase subunit 5; K03883 NADH-ubiquinone oxidoreductase chain 5 [EC:1.6.5.3] [KO:K03883] [EC:1.6.5.3]
ND6  
NADH dehydrogenase subunit 6; K03884 NADH-ubiquinone oxidoreductase chain 6 [EC:1.6.5.3] [KO:K03884] [EC:1.6.5.3]
NADH-ubiquinone oxidoreductase 75 kDa subunit; K03934 NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3] [KO:K03934] [EC:1.6.99.3 1.6.5.3]
NADH-ubiquinone oxidoreductase 49 kDa subunit; K03935 NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3] [KO:K03935] [EC:1.6.99.3 1.6.5.3]
Probable NADH-ubiquinone oxidoreductase 49 kDa subunit; K03935 NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3] [KO:K03935] [EC:1.6.99.3 1.6.5.3]
NADH-ubiquinone oxidoreductase 30 kDa subunit; K03936 NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:1.6.5.3 1.6.99.3] [KO:K03936] [EC:1.6.99.3 1.6.5.3]
ETC complex I subunit conserved region family protein; K03937 NADH dehydrogenase (ubiquinone) Fe-S protein 4 [KO:K03937]
NADH-ubiquinone oxidoreductase 15 kDa subunit; K03938 NADH dehydrogenase (ubiquinone) Fe-S protein 5 [KO:K03938]
Probable NADH-ubiquinone oxidoreductase 13 kDa-A subunit; K03939 NADH dehydrogenase (ubiquinone) Fe-S protein 6 [KO:K03939]
Probable NADH-ubiquinone oxidoreductase 20 kDa subunit; K03940 NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:1.6.5.3 1.6.99.3] [KO:K03940] [EC:1.6.99.3 1.6.5.3]
NADH-ubiquinone oxidoreductase 23 kDa subunit; K03941 NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:1.6.5.3 1.6.99.3] [KO:K03941] [EC:1.6.99.3 1.6.5.3]
NADH-ubiquinone oxidoreductase 51 kDa subunit; K03942 NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.5.3 1.6.99.3] [KO:K03942] [EC:1.6.99.3 1.6.5.3]
NADH-ubiquinone oxidoreductase 24 kDa subunit; K03943 NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:1.6.5.3 1.6.99.3] [KO:K03943] [EC:1.6.99.3 1.6.5.3]
RH49308p; K03945 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1 [KO:K03945]
NADH-ubiquinone oxidoreductase B8 subunit; K03946 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2 [KO:K03946]
NADH-ubiquinone oxidoreductase 17.3 kDa subunit; K03949 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5 [KO:K03949]
hypothetical protein; K03951 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7 [KO:K03951]
NADH-ubiquinone oxidoreductase 19 kDa subunit; K03952 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8 [KO:K03952]
NADH-ubiquinone oxidoreductase 39 kDa subunit; K03953 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9 [KO:K03953]
Deoxynucleoside kinase family protein; K03954 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10 [KO:K03954]
acyl carrier protein; K03955 NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1 [KO:K03955]
Phosphopantetheine attachment site family protein; K03955 NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1 [KO:K03955]
NADH-ubiquinone oxidoreductase subunit B17.2; K11352 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12 [KO:K11352]
GRIM-19 protein; K11353 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13 [KO:K11353]
NADH-ubiquinone oxidoreductase AGGG subunit homolog; K03958 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2 [KO:K03958]
NADH-ubiquinone oxidoreductase B12 subunit; K03959 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3 [KO:K03959]
hypothetical protein; K03960 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4 [KO:K03960]
RH17657p; K03961 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5 [KO:K03961]
symbol; K03962 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6 [KO:K03962]
Probable NADH-ubiquinone oxidoreductase B18 subunit; K03963 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7 [KO:K03963]
NADH-ubiquinone oxidoreductase ASHI subunit; K03964 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8 [KO:K03964]
NADH-ubiquinone oxidoreductase B22 subunit; K03965 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9 [KO:K03965]
hypothetical protein; K03966 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10 [KO:K03966]
GH05862p; K11351 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11 [KO:K11351]
NADH-ubiquinone oxidoreductase subunit B14.5b; K03968 NADH dehydrogenase (ubiquinone) 1 subunit C2 [KO:K03968]
Succinate dehydrogenase cytochrome b560 subunit; K00236 succinate dehydrogenase (ubiquinone) cytochrome b560 subunit [KO:K00236]
Succinate dehydrogenase; K00237 succinate dehydrogenase (ubiquinone) membrane anchor subunit [KO:K00237]
succinate dehydrogenase [ubiquinone] flavoprotein subunit; K00234 succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1] [KO:K00234] [EC:1.3.5.1]
succinate dehydrogenase [ubiquinone] iron-sulfur protein; K00235 succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1] [KO:K00235] [EC:1.3.5.1]
ubiquinol-cytochrome c reductase; K00411 ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2] [KO:K00411] [EC:1.10.2.2]
CYTB  
cytochrome b; K00412 ubiquinol-cytochrome c reductase cytochrome b subunit [KO:K00412]
Cytochrome C1 family protein; K00413 ubiquinol-cytochrome c reductase cytochrome c1 subunit [KO:K00413]
Peptidase M16 inactive domain containing protein; K00415 ubiquinol-cytochrome c reductase core subunit 2 [KO:K00415]
Ubiquinol-cytochrome C reductase hinge protein; K00416 ubiquinol-cytochrome c reductase subunit 6 [KO:K00416]
UcrQ family protein; K00418 ubiquinol-cytochrome c reductase subunit 8 [KO:K00418]
hypothetical protein; K00419 ubiquinol-cytochrome c reductase subunit 9 [KO:K00419]
hypothetical protein; K00420 ubiquinol-cytochrome c reductase subunit 10 [KO:K00420]
protoheme IX farnesyltransferase family protein; K02257 protoheme IX farnesyltransferase [EC:2.5.1.-] [KO:K02257] [EC:2.5.1.-]
COX3  
cytochrome c oxidase subunit III; K02262 cytochrome c oxidase subunit 3 [KO:K02262]
COX1  
cytochrome c oxidase subunit I; K02256 cytochrome c oxidase subunit 1 [EC:1.9.3.1] [KO:K02256] [EC:1.9.3.1]
COX2  
cytochrome c oxidase subunit II; K02261 cytochrome c oxidase subunit 2 [KO:K02261]
Cytochrome c oxidase subunit IV family protein; K02263 cytochrome c oxidase subunit 4 [KO:K02263]
Cytochrome c oxidase polypeptide Va; K02264 cytochrome c oxidase subunit 5a [KO:K02264]
Cytochrome c oxidase polypeptide Vb; K02265 cytochrome c oxidase subunit 5b [KO:K02265]
Cytochrome c oxidase subunit VIa family protein; K02266 cytochrome c oxidase subunit 6a [KO:K02266]
cytochrome oxidase c subunit VIb family protein; K02267 cytochrome c oxidase subunit 6b [KO:K02267]
Cytochrome c oxidase assembly protein CtaG / Cox11 containing protein; K02258 cytochrome c oxidase assembly protein subunit 11 [KO:K02258]
Cytochrome oxidase assembly protein; K02259 cytochrome c oxidase assembly protein subunit 15 [KO:K02259]
cytochrome c oxidase copper chaperone; K02260 cytochrome c oxidase assembly protein subunit 17 [KO:K02260]
ATP synthase alpha chain; K02132 F-type H+-transporting ATPase subunit alpha [KO:K02132]
ATP synthase beta chain; K02133 F-type H+-transporting ATPase subunit beta [EC:3.6.3.14] [KO:K02133] [EC:3.6.3.14]
ATP synthase gamma chain; K02136 F-type H+-transporting ATPase subunit gamma [KO:K02136]
ATP synthase delta chain; K02134 F-type H+-transporting ATPase subunit delta [KO:K02134]
ATP synthase epsilon chain; K02135 F-type H+-transporting ATPase subunit epsilon [KO:K02135]
ATP synthase F1; K02137 F-type H+-transporting ATPase subunit O [KO:K02137]
hypothetical protein; K02137 F-type H+-transporting ATPase subunit O [KO:K02137]
ATP synthase B chain; K02127 F-type H+-transporting ATPase subunit b [KO:K02127]
ATP synthase lipid-binding protein; K02128 F-type H+-transporting ATPase subunit c [KO:K02128]
hypothetical protein; K02138 F-type H+-transporting ATPase subunit d [KO:K02138]
ATP synthase e chain; K02129 F-type H+-transporting ATPase subunit e [KO:K02129]
ATP synthase e chain; K02129 F-type H+-transporting ATPase subunit e [KO:K02129]
ATP synthase f chain; K02130 F-type H+-transporting ATPase subunit f [KO:K02130]
Mitochondrial ATP synthase g subunit family protein; K02140 F-type H+-transporting ATPase subunit g [KO:K02140]
vacuolar ATP synthase catalytic subunit A; K02145 V-type H+-transporting ATPase subunit A [EC:3.6.3.14] [KO:K02145] [EC:3.6.3.14]
vacuolar ATP synthase subunit B; K02147 V-type H+-transporting ATPase subunit B [KO:K02147]
V-ATPase subunit C family protein; K02148 V-type H+-transporting ATPase subunit C [KO:K02148]
vacuolar ATP synthase subunit D; K02149 V-type H+-transporting ATPase subunit D [KO:K02149]
Vacuolar h atpase protein 8; K02150 V-type H+-transporting ATPase subunit E [KO:K02150]
Vacuolar ATP synthase subunit F; K02151 V-type H+-transporting ATPase subunit F [KO:K02151]
vacuolar ATP synthase subunit G; K02152 V-type H+-transporting ATPase subunit G [KO:K02152]
vacuolar proton pump; K02154 V-type H+-transporting ATPase subunit a [KO:K02154]
vacuolar proton pump; K02154 V-type H+-transporting ATPase subunit a [KO:K02154]
Vacuolar ATP synthase 16 kDa proteolipid subunit 1; K02155 V-type H+-transporting ATPase 16kDa proteolipid subunit [KO:K02155]
Vacuolar ATP synthase 16 kDa proteolipid subunit; K02155 V-type H+-transporting ATPase 16kDa proteolipid subunit [KO:K02155]
Vacuolar ATP synthase 21 kDa proteolipid subunit; K03661 V-type H+-transporting ATPase 21kDa proteolipid subunit [KO:K03661]
Vacuolar h atpase protein 16; K02146 V-type H+-transporting ATPase subunit d [KO:K02146]
vacuolar ATP synthase subunit H; K02153 V-type H+-transporting ATPase subunit e [KO:K02153]
hypothetical protein; K03662 V-type H+-transporting ATPase S1 subunit [KO:K03662]
inorganic pyrophosphatase; K01507 inorganic pyrophosphatase [EC:3.6.1.1] [KO:K01507] [EC:3.6.1.1]
Compound
C00001  
H2O
C00002  
ATP
C00003  
NAD+
C00004  
NADH
C00007  
Oxygen
C00008  
ADP
C00009  
Orthophosphate
C00013  
Diphosphate
C00042  
Succinate
C00061  
FMN
C00080  
H+
C00122  
Fumarate
C00390  
Ubiquinol
C00399  
Ubiquinone
C00524  
Cytochrome c
C00536  
Triphosphate
Reference
  Authors
Sazanov LA, Hinchliffe P.
  Title
Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus.
  Journal
Science 311:1430-6 (2006)
Reference
  Authors
Hinchliffe P, Carroll J, Sazanov LA.
  Title
Identification of a novel subunit of respiratory complex I from Thermus thermophilus.
  Journal
Biochemistry 45:4413-20 (2006)
KO pathway
 

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