KEGG   PATHWAY: bmz00630
Entry
bmz00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Brucella melitensis M28
Class
Metabolism; Carbohydrate metabolism
Pathway map
bmz00630  Glyoxylate and dicarboxylate metabolism
bmz00630

Module
bmz_M00012  Glyoxylate cycle [PATH:bmz00630]
bmz_M00621  Glycine cleavage system [PATH:bmz00630]
bmz_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:bmz00630]
Other DBs
GO: 0046487 0043648
Organism
Brucella melitensis M28 [GN:bmz]
Gene
BM28_A1619  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
BM28_A1803  acsA; acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
BM28_B0427  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
BM28_A1649  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
BM28_A1918  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BM28_A1156  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
BM28_A0096  acnA; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
BM28_B0762  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BM28_A1767  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BM28_B0425  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BM28_A0830  Glyoxalase/Bleomycin resistance protein/dioxygenase domain protein [KO:K05606] [EC:5.1.99.1]
BM28_A1196  Propionyl-COA carboxylase alpha chain [KO:K01965] [EC:6.4.1.3]
BM28_A1195  propionyl-CoA carboxylase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
BM28_A1197  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
BM28_B0175  ATPase, E1-E2 type [KO:K00104] [EC:1.1.99.14]
BM28_B0176  FAD linked oxidase domain-containing protein [KO:K11472] [EC:1.1.99.14]
BM28_B0177  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
BM28_B0345  Catalase [KO:K03781] [EC:1.11.1.6]
BM28_A2165  glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
BM28_A0005  D-isomer specific 2-hydroxyacid dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BM28_A0318  HAD-superfamily hydrolase [KO:K01091] [EC:3.1.3.18]
BM28_A1011  HAD-superfamily hydrolase [KO:K01091] [EC:3.1.3.18]
BM28_A1017  cbbZ; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
BM28_A1013  glnA; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
BM28_B0700  glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
BM28_B0733  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
BM28_A0774  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
BM28_B0693  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
BM28_B0695  gcvT; glycine cleavage system aminomethyltransferase T [KO:K00605] [EC:2.1.2.10]
BM28_A1134  lpdA; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
BM28_B0500  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
BM28_A1909  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
BM28_B0694  gcvH; glycine cleavage system protein H [KO:K02437]
BM28_A0386  putative hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
BM28_B0087  keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
BM28_B0874  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BM28_B0900  hutG; N-formylglutamate amidohydrolase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bmz00010  Glycolysis / Gluconeogenesis
bmz00020  Citrate cycle (TCA cycle)
bmz00030  Pentose phosphate pathway
bmz00053  Ascorbate and aldarate metabolism
bmz00071  Fatty acid degradation
bmz00230  Purine metabolism
bmz00250  Alanine, aspartate and glutamate metabolism
bmz00260  Glycine, serine and threonine metabolism
bmz00620  Pyruvate metabolism
bmz00750  Vitamin B6 metabolism
bmz00910  Nitrogen metabolism
KO pathway
ko00630   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (37)   
   KEGG GENES (37)   
All databases (38)   

Download RDF
DBGET integrated database retrieval system