KEGG   PATHWAY: bpq00230
Entry
bpq00230                    Pathway                                
Name
Purine metabolism - Burkholderia pseudomallei BPC006
Class
Metabolism; Nucleotide metabolism
Pathway map
bpq00230  Purine metabolism
bpq00230

Module
bpq_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bpq00230]
bpq_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bpq00230]
bpq_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bpq00230]
bpq_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bpq00230]
bpq_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bpq00230]
bpq_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:bpq00230]
bpq_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:bpq00230]
Other DBs
GO: 0006163 0042278
Organism
Burkholderia pseudomallei BPC006 [GN:bpq]
Gene
BPC006_I1358  NUDIX family hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
BPC006_I3163  phosphoglucomutase/phosphomannomutase family protein [KO:K15778] [EC:5.4.2.8 5.4.2.2]
BPC006_I0575  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
BPC006_II2274  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
BPC006_I1287  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
BPC006_I0960  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BPC006_I1244  phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
BPC006_I2385  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
BPC006_I3349  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
BPC006_I0835  phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
BPC006_I0834  phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
BPC006_I0833  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BPC006_I3486  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BPC006_I3449  bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BPC006_I0595  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BPC006_I2283  stationary phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
BPC006_I2249  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BPC006_I3568  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
BPC006_I2499  inosine 5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
BPC006_I2275  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
BPC006_I3054  putative deoxyribonucleotide triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
BPC006_I3241  xanthine dehydrogenase family protein, iron-sulfur-binding/FAD-binding subunit [KO:K13481] [EC:1.17.1.4]
BPC006_I3240  xanthine dehydrogenase, molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
BPC006_I2496  GMP synthase [KO:K01951] [EC:6.3.5.2]
BPC006_I4116  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
BPC006_I3013  guanine deaminase [KO:K01487] [EC:3.5.4.3]
BPC006_I3051  guanylate kinase [KO:K00942] [EC:2.7.4.8]
BPC006_II3030  ribonucleotide reductase-like protein [KO:K00525] [EC:1.17.4.1]
BPC006_II0695  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
BPC006_I3562  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
BPC006_I3561  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
BPC006_I2783  anaerobic ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
BPC006_I3808  deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
BPC006_I3049  GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BPC006_I1571  Ppx/GppA phosphatase family protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BPC006_I1781  GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
BPC006_I0745  response regulator/HD domain-containing protein [KO:K01768] [EC:4.6.1.1]
BPC006_I2261  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
BPC006_I3557  PfkB family kinase [KO:K00856] [EC:2.7.1.20]
BPC006_II2382  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
BPC006_I3011  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
BPC006_I0434  putative 2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
BPC006_I0915  adenylate kinase [KO:K00939] [EC:2.7.4.3]
BPC006_I1457  Ser/Thr protein phosphatase family protein [KO:K03651] [EC:3.1.4.53]
BPC006_I3186  diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
BPC006_I2101  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
BPC006_I2774  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
BPC006_II2581  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
BPC006_I2625  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
BPC006_I1007  sulfate adenylyltransferase, large subunit [KO:K00956] [EC:2.7.7.4]
BPC006_I1006  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
BPC006_I2608  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
BPC006_I2470  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
BPC006_I2475  hypothetical protein [KO:K13485] [EC:4.1.1.97]
BPC006_I2477  hydantoin racemase [KO:K16841] [EC:5.1.99.3]
BPC006_I2088  putative D-hydantoinase [KO:K01466] [EC:3.5.2.5]
BPC006_I2476  polysaccharide deacetylase [KO:K16842] [EC:3.5.2.5]
BPC006_I2474  allantoicase [KO:K01477] [EC:3.5.3.4]
BPC006_I3505  allantoicase [KO:K01477] [EC:3.5.3.4]
BPC006_I2473  ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
BPC006_I3504  ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
BPC006_II2831  fumarylacetoacetate hydrolase family protein [KO:K16856] [EC:4.3.2.3]
BPC006_I3156  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
BPC006_I3155  urease subunit beta [KO:K01429] [EC:3.5.1.5]
BPC006_I3154  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
BPC006_I2036  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bpq00030  Pentose phosphate pathway
bpq00220  Arginine biosynthesis
bpq00250  Alanine, aspartate and glutamate metabolism
bpq00260  Glycine, serine and threonine metabolism
bpq00340  Histidine metabolism
bpq00630  Glyoxylate and dicarboxylate metabolism
bpq00730  Thiamine metabolism
bpq00740  Riboflavin metabolism
bpq00790  Folate biosynthesis
KO pathway
ko00230   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (66)   
   KEGG GENES (66)   
All databases (67)   

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