| Entry |
|
| Name |
Glycerophospholipid metabolism - Bradyrhizobium sp. ORS 278
|
| Class |
Metabolism; Lipid metabolism
 |
| Pathway map |
| Glycerophospholipid metabolism |

  |
| Module |
| Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH: bra00564] | | Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH: bra00564] | | Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH: bra00564] | | Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH: bra00564] |
|
| Other DBs |
|
| Organism |
Bradyrhizobium sp. ORS 278 [GN: bra]
|
| Gene |
| gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [KO: K00057] [EC: 1.1.1.94] | | glpD; glycerol-3-phosphate dehydrogenase [KO: K00111] [EC: 1.1.5.3] | | glpD; glycerol-3-phosphate dehydrogenase [KO: K00111] [EC: 1.1.5.3] | | glpD; glycerol-3-phosphate dehydrogenase [KO: K00111] [EC: 1.1.5.3] | | plsX; glycerol-3-phosphate acyltransferase PlsX [KO: K03621] [EC: 2.3.1.15] | | glycerol-3-phosphate acyltransferase PlsY; K08591 glycerol-3-phosphate acyltransferase PlsY [EC: 2.3.1.15] [KO: K08591] [EC: 2.3.1.15] | | 1-acylglycerol-3-phosphate O-acyltransferase; K00655 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC: 2.3.1.51] [KO: K00655] [EC: 2.3.1.51] | | diacylglycerol kinase (DgkA-like); K00901 diacylglycerol kinase (ATP dependent) [EC: 2.7.1.107] [KO: K00901] [EC: 2.7.1.107] | | | | phosphoesterase family protein signal peptide; K01114 phospholipase C [EC: 3.1.4.3] [KO: K01114] [EC: 3.1.4.3] | | | | glycerophosphoryl diester phosphodiesterase; K01126 glycerophosphoryl diester phosphodiesterase [EC: 3.1.4.46] [KO: K01126] [EC: 3.1.4.46] | | acylglycerophosphoethanolamine acyltransferase; K05939 acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid--[acyl-carrier-protein] ligase [EC: 2.3.1.40 6.2.1.20] [KO: K05939] [EC: 6.2.1.20 2.3.1.40] | | eutB; ethanolamine ammonia-lyase heavy chain [KO: K03735] [EC: 4.3.1.7] | | eutC; ethanolamine ammonia-lyase light chain [KO: K03736] [EC: 4.3.1.7] | | | | | | N-methyltransferase phosphatidylethanolamine or menaquinone biosynthesis methyltransferase (ubiE); K00570 phosphatidylethanolamine/phosphatidyl-N-methylethanolamine N-methyltransferase [EC: 2.1.1.17 2.1.1.71] [KO: K00570] [EC: 2.1.1.71 2.1.1.17] | | | | | | | | phosphatidylserine decarboxylase; K01613 phosphatidylserine decarboxylase [EC: 4.1.1.65] [KO: K01613] [EC: 4.1.1.65] | | | | pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [KO: K00995] [EC: 2.7.8.5] | | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; K00995 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [EC: 2.7.8.5] [KO: K00995] [EC: 2.7.8.5] |
|
| Compound |
| Acyl-CoA | | Acetaldehyde | | sn-Glycerol 3-phosphate | | Glycerone phosphate | | Choline | | Phosphatidylcholine | | Ethanolamine | | CDP-diacylglycerol | | CDP-choline | | Phosphatidylglycerol | | Ethanolamine phosphate | | Phosphatidylethanolamine | | Phosphatidate | | CDP-glycerol | | CDP-ethanolamine | | Choline phosphate | | sn-Glycerol 1-phosphate | | 1,2-Diacyl-sn-glycerol | | sn-glycero-3-Phosphocholine | | 1-Acyl-sn-glycerol 3-phosphate | | 1-Phosphatidyl-D-myo-inositol | | N-Methylethanolamine phosphate | | sn-glycero-3-Phosphoethanolamine | | Phosphatidyl-N-methylethanolamine | | Acetylcholine | | Phosphatidylserine | | Acylglycerone phosphate | | 1-Acylglycerophosphoinositol | | L-Serine-phosphoethanolamine | | Phosphatidylglycerophosphate | | 2-Acyl-sn-glycerol 3-phosphate | | 1-Acyl-sn-glycero-3-phosphocholine | | 2-Acyl-sn-glycero-3-phosphocholine | | Phosphatidyl-N-dimethylethanolamine | | 1-Acyl-sn-glycero-3-phosphoethanolamine | | 3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate | | 2,3-Bis-O-(geranylgeranyl)glycerol 1-phosphate | | 2-Acyl-sn-glycero-3-phosphoethanolamine | | 2-Acyl-sn-glycero-3-phosphoserine | | Aminoacyl-phosphatidylglycerol | | Cardiolipin | | Triethanolamine | | Diethanolamine | | Phosphodimethylethanolamine | | CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol | | 1-Acyl-sn-glycero-3-phosphoserine | | 1-Acyl-sn-glycero-3-phosphoglycerol | | Monolysocardiolipin | | Diacylglycerylhomoserine | | Diacylglyceryl-N,N,N-trimethylhomoserine | | 2,3-Bis-O-(geranylgeranyl)-sn-glycero-1-phospho-L-serine |
|
| Reference |
|
| Authors |
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML. |
| Title |
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae. |
| Journal |
J Bacteriol 174:5702-10 (1992) |
| Reference |
|
| Authors |
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M. |
| Title |
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase. |
| Journal |
Biochem Biophys Res Commun 257:50-6 (1999) |
| Reference |
|
| Authors |
Athenstaedt K, Daum G. |
| Title |
Phosphatidic acid, a key intermediate in lipid metabolism. |
| Journal |
Eur J Biochem 266:1-16 (1999) |
| Reference |
|
| Authors |
Shields DJ, Lehner R, Agellon LB, Vance DE. |
| Title |
Membrane topography of human phosphatidylethanolamine N-methyltransferase. |
| Journal |
J Biol Chem 278:2956-62 (2003) |
| Reference |
|
| Authors |
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O. |
| Title |
Pathways for phosphatidylcholine biosynthesis in bacteria. |
| Journal |
Microbiology 149:3461-71 (2003) |
| Reference |
|
| Authors |
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G. |
| Title |
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae. |
| Journal |
Biochim Biophys Acta 1686:161-8 (2004) |
| Reference |
|
| Authors |
Hsu L, Jackowski S, Rock CO. |
| Title |
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity. |
| Journal |
J Biol Chem 266:13783-8 (1991) |
| Reference |
|
| Authors |
Stone SJ, Vance JE. |
| Title |
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes. |
| Journal |
J Biol Chem 275:34534-40 (2000) |
| KO pathway |
|