KEGG   PATHWAY: bta00190Help
Entry
bta00190                    Pathway                                

Name
Oxidative phosphorylation - Bos taurus (cow)
Class
Metabolism; Energy metabolism
BRITE hierarchy
Pathway map
Oxidative phosphorylation
bta00190

All organismsOrtholog table
Module
NADH:ubiquinone oxidoreductase, mitochondria [PATH:bta00190]
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:bta00190]
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex [PATH:bta00190]
NADH dehydrogenase (ubiquinone) 1 beta subcomplex [PATH:bta00190]
Succinate dehydrogenase (ubiquinone) [PATH:bta00190]
Cytochrome bc1 complex respiratory unit [PATH:bta00190]
Cytochrome bc1 complex [PATH:bta00190]
Cytochrome c oxidase [PATH:bta00190]
F-type ATPase, eukaryotes [PATH:bta00190]
V-type ATPase, eukaryotes [PATH:bta00190]
Organism
Bos taurus (cow) [GN:bta]
Gene
ND1; NADH dehydrogenase subunit 1 [KO:K03878] [EC:1.6.5.3]
ND2; NADH dehydrogenase subunit 2 [KO:K03879] [EC:1.6.5.3]
ND3; NADH dehydrogenase subunit 3 [KO:K03880] [EC:1.6.5.3]
ND4; NADH dehydrogenase subunit 4 [KO:K03881] [EC:1.6.5.3]
ND4L; NADH dehydrogenase subunit 4L [KO:K03882] [EC:1.6.5.3]
ND5; NADH dehydrogenase subunit 5 [KO:K03883] [EC:1.6.5.3]
ND6; NADH dehydrogenase subunit 6 [KO:K03884] [EC:1.6.5.3]
288380  
NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) [KO:K03934] [EC:1.6.99.3 1.6.5.3]
327697  
NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) [KO:K03935] [EC:1.6.99.3 1.6.5.3]
287327  
NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) [KO:K03936] [EC:1.6.99.3 1.6.5.3]
327680  
NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) [KO:K03937]
338057  
NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) [KO:K03938]
327691  
NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) [KO:K03939]
338079  
NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) [KO:K03940] [EC:1.6.99.3 1.6.5.3]
287027  
NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) [KO:K03941] [EC:1.6.99.3 1.6.5.3]
287014  
NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa [KO:K03942] [EC:1.6.99.3 1.6.5.3]
282290  
NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa [KO:K03943] [EC:1.6.99.3 1.6.5.3]
781824  
NDUFV2; NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial-like [KO:K03943] [EC:1.6.99.3 1.6.5.3]
327717  
NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa [KO:K03944]
327673  
NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa [KO:K03945]
327698  
NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa [KO:K03946]
338064  
NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa [KO:K03947]
327704  
NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa [KO:K03948]
613541  
NDUFA4L2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 [KO:K03948]
327714  
NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa [KO:K03949]
327670  
NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa [KO:K03950]
338063  
NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa [KO:K03951]
327710  
NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa [KO:K03952]
404188  
NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa [KO:K03953]
338060  
NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa [KO:K03954]
327702  
NDUFAB1; NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa [KO:K03955]
326346  
NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa [KO:K03956]
281742  
NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 [KO:K11352]
338084  
NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 [KO:K11353]
327690  
NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa [KO:K03957]
327713  
NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa [KO:K03958]
338073  
NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa [KO:K03959]
327706  
NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa [KO:K03960]
338061  
NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa [KO:K03961]
327665  
NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa [KO:K03962]
338065  
NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa [KO:K03963]
282517  
NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa [KO:K03964]
327660  
NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa [KO:K03965]
327701  
NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa [KO:K03966]
404161  
NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa [KO:K11351]
282289  
NDUFC1; NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa [KO:K03967]
338046  
NDUFC2; NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa [KO:K03968]
281480  
SDHA; succinate dehydrogenase complex, subunit A, flavoprotein (Fp) [KO:K00234] [EC:1.3.5.1]
286840  
SDHB; succinate dehydrogenase complex, subunit B, iron sulfur (Ip) [KO:K00235] [EC:1.3.5.1]
327696  
SDHC; succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa [KO:K00236]
281481  
SDHD; succinate dehydrogenase complex, subunit D, integral membrane protein [KO:K00237]
287020  
UQCRFS1; ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 [KO:K00411] [EC:1.10.2.2]
CYTB; cytochrome b [KO:K00412]
512500  
CYC1; cytochrome c-1 [KO:K00413]
282393  
UQCRC1; ubiquinol-cytochrome c reductase core protein I [KO:K00414]
282394  
UQCRC2; ubiquinol-cytochrome c reductase core protein II [KO:K00415]
613899  
UQCRH; ubiquinol-cytochrome c reductase hinge protein [KO:K00416]
616871  
UQCRB; ubiquinol-cytochrome c reductase binding protein [KO:K00417]
286885  
UQCRQ; ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa [KO:K00418]
616109  
UQCR10; ubiquinol-cytochrome c reductase, complex III subunit X [KO:K00419]
281570  
UQCR11; ubiquinol-cytochrome c reductase, complex III subunit XI [KO:K00420]
511440  
COX10; COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) [KO:K02257] [EC:2.5.1.-]
COX3; cytochrome c oxidase subunit III [KO:K02262]
COX1; cytochrome c oxidase subunit I [KO:K02256] [EC:1.9.3.1]
COX2; cytochrome c oxidase subunit II [KO:K02261]
281090  
COX4I1; cytochrome c oxidase subunit IV isoform 1 [KO:K02263]
618339  
COX4I2; cytochrome c oxidase subunit IV isoform 2 (lung) [KO:K02263]
444878  
COX5A; cytochrome c oxidase subunit Va [KO:K02264]
287012  
COX5B; cytochrome c oxidase subunit Vb [KO:K02265]
282200  
COX6A2; cytochrome c oxidase subunit VIa polypeptide 2 [KO:K02266]
282199  
COX6A1; cytochrome c oxidase subunit VIa polypeptide 1 [KO:K02266]
cytochrome c oxidase subunit 6A1; K02266 cytochrome c oxidase subunit 6a [KO:K02266]
cytochrome c oxidase subunit 6A1; K02266 cytochrome c oxidase subunit 6a [KO:K02266]
503554  
COX6B2; cytochrome c oxidase subunit VIb polypeptide 2 (testis) [KO:K02267]
COX6B1; cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) [KO:K02267]
614700  
MGC148714; cytochrome c oxidase subunit 6C [KO:K02268]
327688  
COX7A2; cytochrome c oxidase subunit VIIa polypeptide 2 (liver) [KO:K02270]
338086  
COX7A1; cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) [KO:K02270]
540225  
COX7A2L; cytochrome c oxidase subunit VIIa polypeptide 2 like [KO:K02270]
cytochrome c oxidase subunit 7A2; K02270 cytochrome c oxidase subunit 7a [KO:K02270]
COX7B; cytochrome c oxidase subunit VIIb [KO:K02271]
767916  
COX7B2; cytochrome c oxidase subunit 7B2, mitochondrial [KO:K02271]
cytochrome c oxidase subunit 7C; K02272 cytochrome c oxidase subunit 7c [KO:K02272]
281091  
COX8A; cytochrome c oxidase subunit VIIIA (ubiquitous) [KO:K02273]
783202  
cytochrome c oxidase subunit 8A; K02273 cytochrome c oxidase subunit 8 [KO:K02273]
615757  
COX8B; cytochrome c oxidase subunit VIII-H (heart/muscle) [KO:K02273]
uncharacterized LOC100300759; K02273 cytochrome c oxidase subunit 8 [KO:K02273]
510509  
COX11; COX11 cytochrome c oxidase assembly homolog (yeast) [KO:K02258]
517811  
COX15; COX15 homolog, cytochrome c oxidase assembly protein (yeast) [KO:K02259]
COX17; COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) [KO:K02260]
282578  
ATP5A1; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle [KO:K02132]
327675  
ATP5B; ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide [KO:K02133] [EC:3.6.3.14]
327668  
ATP5C1; ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 [KO:K02136]
783991  
ATP synthase subunit gamma; K02136 F-type H+-transporting ATPase subunit gamma [KO:K02136]
338081  
ATP5D; ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit [KO:K02134]
617230  
ATP5E; ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit [KO:K02135]
782270  
aTP synthase; K02135 F-type H+-transporting ATPase subunit epsilon [KO:K02135]
ATP synthase subunit epsilon; K02135 F-type H+-transporting ATPase subunit epsilon [KO:K02135]
ATP synthase subunit epsilon; K02135 F-type H+-transporting ATPase subunit epsilon [KO:K02135]
281640  
ATP5O; ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit [KO:K02137]
ATP6; ATP synthase F0 subunit 6 [KO:K02126]
282701  
ATP5F1; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 [KO:K02127]
540176  
ATP5G3; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) [KO:K02128]
337887  
ATP5G2; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) [KO:K02128]
338053  
ATP5G1; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) [KO:K02128]
282710  
ATP5H; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d [KO:K02138]
338040  
ATP5I; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E [KO:K02129]
506492  
ATP5J2; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 [KO:K02130]
515696  
ATP5L; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G [KO:K02140]
ATP synthase subunit g; K02140 F-type H+-transporting ATPase subunit g [KO:K02140]
282690  
ATP5J; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 [KO:K02131]
ATP8; ATP synthase F0 subunit 8 [KO:K02125]
282147  
ATP6V1A; ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A [KO:K02145] [EC:3.6.3.14]
338082  
ATP6V1B2; ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 [KO:K02147]
338059  
ATP6V1B1; ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 [KO:K02147]
338089  
ATP6V1C1; ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 [KO:K02148]
508327  
ATP6V1C2; ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 [KO:K02148]
404152  
ATP6V1D; ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D [KO:K02149]
287017  
ATP6V1E1; ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 [KO:K02150]
540113  
ATP6V1E2; ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2 [KO:K02150]
282405  
ATP6V1F; ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F [KO:K02151]
281641  
ATP6V1G1; ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 [KO:K02152]
613925  
ATP6V1G3; ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3 [KO:K02152]
514368  
ATP6V1G2; ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 [KO:K02152]
282657  
ATP6V1H; ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H [KO:K02144]
338038  
ATP6V0A2; ATPase, H+ transporting, lysosomal V0 subunit a2 [KO:K02154]
286768  
ATP6V0A1; ATPase, H+ transporting, lysosomal V0 subunit a1 [KO:K02154]
785923  
V-type proton ATPase 116 kDa subunit a isoform 1-like; K02154 V-type H+-transporting ATPase subunit a [KO:K02154]
518974  
ATP6V0A4; ATPase, H+ transporting, lysosomal V0 subunit a4 [KO:K02154]
513684  
TCIRG1; T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 [KO:K02154]
550622  
ATP6V0C; ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c [KO:K02155]
505684  
ATP6V0B; ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b [KO:K03661]
282148  
ATP6V0D1; ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 [KO:K02146]
511839  
ATP6V0D2; ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 [KO:K02146]
338075  
ATP6V0E1; ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 [KO:K02153]
505224  
ATP6V0E2; ATPase, H+ transporting V0 subunit e2 [KO:K02153]
327687  
ATP6AP1; ATPase, H+ transporting, lysosomal accessory protein 1 [KO:K03662]
521163  
ATP4A; ATPase, H+/K+ exchanging, alpha polypeptide [KO:K01542] [EC:3.6.3.10]
614308  
ATP4B; ATPase, H+/K+ exchanging, beta polypeptide [KO:K01543] [EC:3.6.3.10]
530703  
ATP12A; ATPase, H+/K+ transporting, nongastric, alpha polypeptide [KO:K01544] [EC:3.6.3.10]
280701  
PPA1; pyrophosphatase (inorganic) 1 [KO:K01507] [EC:3.6.1.1]
615820  
PPA2; pyrophosphatase (inorganic) 2 [KO:K01507] [EC:3.6.1.1]
534183  
LHPP; phospholysine phosphohistidine inorganic pyrophosphate phosphatase [KO:K11725] [EC:3.1.3.- 3.6.1.1]
Compound
C00001  
H2O
C00002  
ATP
C00003  
NAD+
C00004  
NADH
C00007  
Oxygen
C00008  
ADP
C00009  
Orthophosphate
C00013  
Diphosphate
C00042  
Succinate
C00061  
FMN
C00080  
H+
C00122  
Fumarate
C00390  
Ubiquinol
C00399  
Ubiquinone
C00524  
Cytochrome c
C00536  
Triphosphate
Reference
  Authors
Sazanov LA, Hinchliffe P.
  Title
Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus.
  Journal
Science 311:1430-6 (2006)
Reference
  Authors
Hinchliffe P, Carroll J, Sazanov LA.
  Title
Identification of a novel subunit of respiratory complex I from Thermus thermophilus.
  Journal
Biochemistry 45:4413-20 (2006)
KO pathway
 

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