KEGG   PATHWAY: byi00362Help
Entry
byi00362                    Pathway                                

Name
Benzoate degradation - Burkholderia sp. YI23
Class
Metabolism; Xenobiotics biodegradation and metabolism
BRITE hierarchy
Pathway map
Benzoate degradation
byi00362

All organismsOrtholog table
Module
Benzene degradation, benzene => catechol [PATH:byi00362]
Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol [PATH:byi00362]
Catechol ortho-cleavage, catechol => 3-oxoadipate [PATH:byi00362]
Other DBs
BSID: 
UMBBD: 
GO: 
Organism
Burkholderia sp. YI23 [GN:byi]
Gene
alpha subunit of aromatic ring hydroxylase component of chlorobenzoate 1; K05549 benzoate/toluate 1,2-dioxygenase alpha subunit [EC:1.14.12.10 1.14.12.-] [KO:K05549] [EC:1.14.12.- 1.14.12.10]
beta subunit of aromatic ring hydroxylase component of chlorobenzoate 1; K05550 benzoate/toluate 1,2-dioxygenase beta subunit [EC:1.14.12.10 1.14.12.-] [KO:K05550] [EC:1.14.12.- 1.14.12.10]
electron transfer component of chlorobenzoate 1; K05784 benzoate/toluate 1,2-dioxygenase reductase subunit [EC:1.18.1.-] [KO:K05784] [EC:1.18.1.-]
cis-diol dehydrogenase; K05783 dihydroxycyclohexadiene carboxylate dehydrogenase [EC:1.3.1.25 1.3.1.-] [KO:K05783] [EC:1.3.1.- 1.3.1.25]
catechol 1; K03381 catechol 1,2-dioxygenase [EC:1.13.11.1] [KO:K03381] [EC:1.13.11.1]
benzenetriol dioxygenase; K03381 catechol 1,2-dioxygenase [EC:1.13.11.1] [KO:K03381] [EC:1.13.11.1]
benzenetriol dioxygenase; K03381 catechol 1,2-dioxygenase [EC:1.13.11.1] [KO:K03381] [EC:1.13.11.1]
catechol 1; K03381 catechol 1,2-dioxygenase [EC:1.13.11.1] [KO:K03381] [EC:1.13.11.1]
catechol 1; K03381 catechol 1,2-dioxygenase [EC:1.13.11.1] [KO:K03381] [EC:1.13.11.1]
muconate and chloromuconate cycloisomerase; K01856 muconate cycloisomerase [EC:5.5.1.1] [KO:K01856] [EC:5.5.1.1]
muconate cycloisomerase; K01856 muconate cycloisomerase [EC:5.5.1.1] [KO:K01856] [EC:5.5.1.1]
muconolactone delta-isomerase; K03464 muconolactone D-isomerase [EC:5.3.3.4] [KO:K03464] [EC:5.3.3.4]
muconolactone delta-isomerase; K03464 muconolactone D-isomerase [EC:5.3.3.4] [KO:K03464] [EC:5.3.3.4]
alpha/beta hydrolase fold protein; K01055 3-oxoadipate enol-lactonase [EC:3.1.1.24] [KO:K01055] [EC:3.1.1.24]
3-oxoadipate enol-lactonase; K01055 3-oxoadipate enol-lactonase [EC:3.1.1.24] [KO:K01055] [EC:3.1.1.24]
alpha/beta hydrolase fold protein; K01055 3-oxoadipate enol-lactonase [EC:3.1.1.24] [KO:K01055] [EC:3.1.1.24]
3-oxoacid CoA-transferase subunit A; K01031 3-oxoadipate CoA-transferase, alpha subunit [EC:2.8.3.6] [KO:K01031] [EC:2.8.3.6]
3-oxoacid CoA-transferase subunit B; K01032 3-oxoadipate CoA-transferase, beta subunit [EC:2.8.3.6] [KO:K01032] [EC:2.8.3.6]
acetyl-CoA acetyltransferase; K00632 acetyl-CoA acyltransferase [EC:2.3.1.16] [KO:K00632] [EC:2.3.1.16]
phenol hydrolase assembly protein; K16249 phenol hydroxylase P0 protein [KO:K16249]
Methane/phenol/toluene hydroxylase; K16243 Phenol hydroxylase P1 protein [KO:K16243]
mmoB_dmpM; monooxygenase component MmoB/DmpM [KO:K16244]
phenol hydrolase alpha subunit; K16242 phenol hydroxylase P3 protein [EC:1.14.13.-] [KO:K16242] [EC:1.14.13.-]
phenol hydroxylase region; K16245 phenol hydroxylase P4 protein [KO:K16245]
phenol 2-monooxygenase; K16246 phenol hydroxylase P5 protein [KO:K16246]
amidohydrolase; K14333 2,3-dihydroxybenzoate decarboxylase [EC:4.1.1.46] [KO:K14333] [EC:4.1.1.46]
4-oxalocrotonate tautomerase; K01821 4-oxalocrotonate tautomerase [EC:5.3.2.6] [KO:K01821] [EC:5.3.2.6]
4-oxalocrotonate tautomerase; K01821 4-oxalocrotonate tautomerase [EC:5.3.2.6] [KO:K01821] [EC:5.3.2.6]
4-oxalocrotonate tautomerase; K01821 4-oxalocrotonate tautomerase [EC:5.3.2.6] [KO:K01821] [EC:5.3.2.6]
hypothetical protein; K01821 4-oxalocrotonate tautomerase [EC:5.3.2.6] [KO:K01821] [EC:5.3.2.6]
intradiol ring-cleavage dioxygenase; K04098 hydroxyquinol 1,2-dioxygenase [EC:1.13.11.37] [KO:K04098] [EC:1.13.11.37]
protocatechuate 3; K00448 protocatechuate 3,4-dioxygenase, alpha subunit [EC:1.13.11.3] [KO:K00448] [EC:1.13.11.3]
protocatechuate 3; K00449 protocatechuate 3,4-dioxygenase, beta subunit [EC:1.13.11.3] [KO:K00449] [EC:1.13.11.3]
fumarate lyase; K01857 3-carboxy-cis,cis-muconate cycloisomerase [EC:5.5.1.2] [KO:K01857] [EC:5.5.1.2]
3-carboxy-cis; K01857 3-carboxy-cis,cis-muconate cycloisomerase [EC:5.5.1.2] [KO:K01857] [EC:5.5.1.2]
carboxymuconolactone decarboxylase; K01607 4-carboxymuconolactone decarboxylase [EC:4.1.1.44] [KO:K01607] [EC:4.1.1.44]
4-carboxymuconolactone decarboxylase; K01607 4-carboxymuconolactone decarboxylase [EC:4.1.1.44] [KO:K01607] [EC:4.1.1.44]
putative carboxymuconolactone decarboxylase; K01607 4-carboxymuconolactone decarboxylase [EC:4.1.1.44] [KO:K01607] [EC:4.1.1.44]
amidohydrolase 2; K10220 4-oxalmesaconate hydratase [EC:4.2.1.83] [KO:K10220] [EC:4.2.1.83]
amidohydrolase; K10220 4-oxalmesaconate hydratase [EC:4.2.1.83] [KO:K10220] [EC:4.2.1.83]
4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase; K10218 4-hydroxy-4-methyl-2-oxoglutarate aldolase [EC:4.1.3.17] [KO:K10218] [EC:4.1.3.17]
4-hydroxybenzoate 3-monooxygenase; K00481 p-hydroxybenzoate 3-monooxygenase [EC:1.14.13.2] [KO:K00481] [EC:1.14.13.2]
thioesterase superfamily protein; K01075 4-hydroxybenzoyl-CoA thioesterase [EC:3.1.2.23] [KO:K01075] [EC:3.1.2.23]
thioesterase superfamily protein; K01075 4-hydroxybenzoyl-CoA thioesterase [EC:3.1.2.23] [KO:K01075] [EC:3.1.2.23]
Enoyl-CoA hydratase/isomerase; K01692 enoyl-CoA hydratase [EC:4.2.1.17] [KO:K01692] [EC:4.2.1.17]
putative enoyl-CoA hydratase/isomerase; K01692 enoyl-CoA hydratase [EC:4.2.1.17] [KO:K01692] [EC:4.2.1.17]
enoyl-CoA hydratase; K01692 enoyl-CoA hydratase [EC:4.2.1.17] [KO:K01692] [EC:4.2.1.17]
Enoyl-CoA hydratase/isomerase; K01692 enoyl-CoA hydratase [EC:4.2.1.17] [KO:K01692] [EC:4.2.1.17]
enoyl-CoA hydratase; K01692 enoyl-CoA hydratase [EC:4.2.1.17] [KO:K01692] [EC:4.2.1.17]
Enoyl-CoA hydratase/isomerase; K01692 enoyl-CoA hydratase [EC:4.2.1.17] [KO:K01692] [EC:4.2.1.17]
3-hydroxybutyryl-CoA dehydrogenase; K00074 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] [KO:K00074] [EC:1.1.1.157]
3-hydroxyacyl-CoA dehydrogenase; K00074 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] [KO:K00074] [EC:1.1.1.157]
3-hydroxyacyl-CoA dehydrogenase; K00074 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] [KO:K00074] [EC:1.1.1.157]
acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Acetyl-CoA C-acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
3-ketoacyl-CoA thiolase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Compound
C00022  
Pyruvate
C00024  
Acetyl-CoA
C00036  
Oxaloacetate
C00084  
Acetaldehyde
C00090  
Catechol
C00091  
Succinyl-CoA
C00146  
Phenol
C00156  
4-Hydroxybenzoate
C00180  
Benzoate
C00196  
2,3-Dihydroxybenzoate
C00230  
3,4-Dihydroxybenzoate
C00332  
Acetoacetyl-CoA
C00512  
S-Benzoate coenzyme A
C00527  
Glutaryl-CoA
C00530  
Hydroquinone
C00587  
3-Hydroxybenzoate
C00596  
2-Hydroxy-2,4-pentadienoate
C00628  
2,5-Dihydroxybenzoate
C00682  
2-Hydroxymuconate semialdehyde
C00846  
3-Oxoadipate
C00877  
Crotonoyl-CoA
C01063  
6-Carboxyhexanoyl-CoA
C01144  
(S)-3-Hydroxybutanoyl-CoA
C01163  
3-Carboxy-cis,cis-muconate
C01278  
2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate
C01407  
Benzene
C02222  
2-Maleylacetate
C02232  
3-Oxoadipyl-CoA
C02411  
Glutaconyl-1-CoA
C02480  
cis,cis-Muconate
C02501  
2-Hydroxymuconate
C02519  
4-Methoxybenzoate
C02814  
Benzene-1,2,4-triol
C02949  
4-Hydroxybenzoyl-CoA
C03453  
gamma-Oxalocrotonate
C03586  
2-Oxo-2,3-dihydrofuran-5-acetate
C03589  
4-Hydroxy-2-oxopentanoate
C03671  
2-Pyrone-4,6-dicarboxylate
C03676  
3-Hydroxy-cis,cis-muconate
C04091  
cis-1,2-Dihydrobenzene-1,2-diol
C04115  
4-Carboxy-4-hydroxy-2-oxoadipate
C04324  
(1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate
C04434  
(1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate
C04480  
3-Carboxy-2-hydroxymuconate semialdehyde
C04484  
4-Carboxy-2-hydroxymuconate semialdehyde
C04553  
3-Carboxy-2,5-dihydro-5-oxofuran-2-acetate
C05375  
2-Hydroxy-2-hydropyrone-4,6-dicarboxylate
C06033  
Parapyruvate
C06035  
4-Methylene-2-oxoglutarate
C06321  
(1R,6S)-1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate
C06322  
Cyclohexa-1,5-diene-1-carbonyl-CoA
C06333  
2-Aminobenzenesulfonate
C06336  
3-Sulfocatechol
C06714  
3-Hydroxypimeloyl-CoA
C06715  
3-Oxopimeloyl-CoA
C06723  
6-Carboxyhex-2-enoyl-CoA
C06749  
6-Hydroxycyclohex-1-ene-1-carbonyl-CoA
C09809  
Cyclohex-2,5-diene-1-carboxyl-CoA
C09810  
Cyclohex-1,4-diene-1-carboxyl-CoA
C09811  
Cyclohex-1-ene-1-carboxyl-CoA
C09812  
2-Hydroxycyclohexane-1-carboxyl-CoA
C09813  
2-Ketocyclohexane-1-carboxyl-CoA
C09821  
6-Oxocyclohex-1-ene-1-carbonyl-CoA
C09822  
Cyclohexane-1-carboxylate
C09823  
Cyclohexane-1-carboxyl-CoA
C14610  
(S)-5-Oxo-2,5-dihydrofuran-2-acetate
Reference
  Authors
Carmona M, Zamarro MT, Blazquez B, Durante-Rodriguez G, Juarez JF, Valderrama JA, Barragan MJ, Garcia JL, Diaz E
  Title
Anaerobic catabolism of aromatic compounds: a genetic and genomic view.
  Journal
Microbiol Mol Biol Rev 73:71-133 (2009)
Reference
  Authors
Hara H, Masai E, Miyauchi K, Katayama Y, Fukuda M.
  Title
Characterization of the 4-carboxy-4-hydroxy-2-oxoadipate aldolase gene and operon structure of the protocatechuate 4,5-cleavage pathway genes in Sphingomonas paucimobilis SYK-6.
  Journal
J Bacteriol 185:41-50 (2003)
Reference
  Authors
Maruyama K, Shibayama T, Ichikawa A, Sakou Y, Yamada S, Sugisaki H.
  Title
Cloning and characterization of the genes encoding enzymes for the protocatechuate meta-degradation pathway of Pseudomonas ochraceae NGJ1.
  Journal
Biosci Biotechnol Biochem 68:1434-41 (2004)
Reference
  Authors
Mampel J, Ruff J, Junker F, Cook AM.
  Title
The oxygenase component of the 2-aminobenzenesulfonate dioxygenase system from Alcaligenes sp. strain O-1.
  Journal
Microbiology 145 ( Pt 11):3255-64 (1999)
Reference
PMID:8002948
  Authors
Junker F, Field JA, Bangerter F, Ramsteiner K, Kohler HP, Joannou CL, Mason JR, Leisinger T, Cook AM.
  Title
Oxygenation and spontaneous deamination of 2-aminobenzenesulphonic acid in Alcaligenes sp. strain O-1 with subsequent meta ring cleavage and spontaneous desulphonation to 2-hydroxymuconic acid.
  Journal
Biochem J 300 ( Pt 2):429-36 (1994)
Reference
PMID:8990279
  Authors
Harwood CS, Gibson J.
  Title
Shedding light on anaerobic benzene ring degradation: a process unique to prokaryotes?
  Journal
J Bacteriol 179:301-9 (1997)
Reference
  Authors
Peters F, Shinoda Y, McInerney MJ, Boll M.
  Title
Cyclohexa-1,5-diene-1-carbonyl-coenzyme A (CoA) hydratases of Geobacter metallireducens and Syntrophus aciditrophicus: Evidence for a common benzoyl-CoA degradation pathway in facultative and strict anaerobes.
  Journal
J Bacteriol 189:1055-60 (2007)
Reference
  Authors
Cowles CE, Nichols NN, Harwood CS.
  Title
BenR, a XylS homologue, regulates three different pathways of aromatic acid degradation in Pseudomonas putida.
  Journal
J Bacteriol 182:6339-46 (2000)
Reference
  Authors
Smith MA, Weaver VB, Young DM, Ornston LN.
  Title
Genes for chlorogenate and hydroxycinnamate catabolism (hca) are linked to functionally related genes in the dca-pca-qui-pob-hca chromosomal cluster of Acinetobacter sp. strain ADP1.
  Journal
Appl Environ Microbiol 69:524-32 (2003)
Reference
  Authors
Kuntze K, Shinoda Y, Moutakki H, McInerney MJ, Vogt C, Richnow HH, Boll M
  Title
6-Oxocyclohex-1-ene-1-carbonyl-coenzyme A hydrolases from obligately anaerobic bacteria: characterization and identification of its gene as a functional marker  for aromatic compounds degrading anaerobes.
  Journal
Environ Microbiol 10:1547-56 (2008)
Reference
  Authors
Pelletier DA, Harwood CS
  Title
2-Hydroxycyclohexanecarboxyl coenzyme A dehydrogenase, an enzyme characteristic of the anaerobic benzoate degradation pathway used by Rhodopseudomonas palustris.
  Journal
J Bacteriol 182:2753-60 (2000)
Reference
  Authors
Elshahed MS, Bhupathiraju VK, Wofford NQ, Nanny MA, McInerney MJ
  Title
Metabolism of benzoate, cyclohex-1-ene carboxylate, and cyclohexane carboxylate by "Syntrophus aciditrophicus" strain SB in syntrophic association with H(2)-using microorganisms.
  Journal
Appl Environ Microbiol 67:1728-38 (2001)
Reference
  Authors
Nogales J, Canales A, Jimenez-Barbero J, Serra B, Pingarron JM, Garcia JL, Diaz E
  Title
Unravelling the gallic acid degradation pathway in bacteria: the gal cluster from Pseudomonas putida.
  Journal
Mol Microbiol 79:359-74 (2011)
KO pathway
 

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