KEGG   PATHWAY: cai00230
Entry
cai00230                    Pathway                                
Name
Purine metabolism - Catenulispora acidiphila
Class
Metabolism; Nucleotide metabolism
Pathway map
cai00230  Purine metabolism
cai00230

Module
cai_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cai00230]
cai_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cai00230]
cai_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cai00230]
cai_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cai00230]
cai_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cai00230]
cai_M00546  Purine degradation, xanthine => urea [PATH:cai00230]
cai_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:cai00230]
cai_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:cai00230]
Other DBs
GO: 0006163 0042278
Organism
Catenulispora acidiphila [GN:cai]
Gene
Caci_6422  NUDIX hydrolase [KO:K13988] [EC:3.6.1.13]
Caci_1729  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Caci_0169  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Caci_0296  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
Caci_0279  phosphoribosylamine/glycine ligase [KO:K01945] [EC:6.3.4.13]
Caci_7981  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Caci_0291  phosphoribosylformylglycinamidine synthase II [KO:K23269] [EC:6.3.5.3]
Caci_0289  phosphoribosylformylglycinamidine synthase, purS [KO:K23264] [EC:6.3.5.3]
Caci_0290  phosphoribosylformylglycinamidine synthase I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
Caci_0297  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
Caci_0840  phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
Caci_0841  phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
Caci_0288  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Caci_0283  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Caci_7980  phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Caci_2358  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
Caci_8958  phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
Caci_2194  HAD-superfamily hydrolase, subfamily IIA [KO:K02566] [EC:3.1.3.5]
Caci_0804  purine nucleotide phosphorylase [KO:K03783] [EC:2.4.2.1]
Caci_6103  protein of unknown function DUF152 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Caci_8427  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Caci_1012  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Caci_1013  IMP dehydrogenase family protein [KO:K00088] [EC:1.1.1.205]
Caci_2331  Nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
Caci_7551  non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
Caci_2736  aldehyde oxidase and xanthine dehydrogenase molybdopterin binding [KO:K11177] [EC:1.17.1.4]
Caci_2735  molybdopterin dehydrogenase FAD-binding [KO:K11178] [EC:1.17.1.4]
Caci_2734  (2Fe-2S)-binding domain protein [KO:K13483]
Caci_1506  GMP synthase, large subunit [KO:K01951] [EC:6.3.5.2]
Caci_2202  IMP dehydrogenase family protein [KO:K26110] [EC:1.7.1.7]
Caci_3479  CMP/dCMP deaminase zinc-binding [KO:K01487] [EC:3.5.4.3]
Caci_5345  guanylate kinase [KO:K00942] [EC:2.7.4.8]
Caci_1817  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
Caci_2042  ribonucleoside-diphosphate reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
Caci_2041  Ribonucleoside-diphosphate reductase [KO:K00526] [EC:1.17.4.1]
Caci_0537  hypothetical protein [KO:K00526] [EC:1.17.4.1]
Caci_7023  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
Caci_2359  (p)ppGpp synthetase I, SpoT/RelA [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Caci_8357  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Caci_0153  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Caci_0817  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Caci_2820  adenylyl cyclase CyaB [KO:K05873] [EC:4.6.1.1]
Caci_7051  Adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
Caci_0271  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
Caci_0498  Adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
Caci_1665  Adenosine kinase [KO:K00856] [EC:2.7.1.20]
Caci_0789  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
Caci_0952  adenylate kinase [KO:K00939] [EC:2.7.4.3]
Caci_8888  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
Caci_2335  histidine triad (HIT) protein [KO:K19710] [EC:2.7.7.53]
Caci_6306  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
Caci_4450  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
Caci_6267  sulfate adenylyltransferase, large subunit [KO:K00956] [EC:2.7.7.4]
Caci_6308  sulfate adenylyltransferase, large subunit [KO:K00956] [EC:2.7.7.4]
Caci_7379  sulfate adenylyltransferase, large subunit [KO:K00956] [EC:2.7.7.4]
Caci_6268  sulfate adenylyltransferase, small subunit [KO:K00957] [EC:2.7.7.4]
Caci_6307  sulfate adenylyltransferase, small subunit [KO:K00957] [EC:2.7.7.4]
Caci_7378  sulfate adenylyltransferase, small subunit [KO:K00957] [EC:2.7.7.4]
Caci_4737  urate oxidase [KO:K00365] [EC:1.7.3.3]
Caci_6402  FAD-dependent pyridine nucleotide-disulphide oxidoreductase [KO:K22879] [EC:1.14.13.113]
Caci_4738  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
Caci_4246  Transthyretin [KO:K07127] [EC:3.5.2.17]
Caci_4739  OHCU decarboxylase [KO:K16840] [EC:4.1.1.97]
Caci_4726  allantoinase [KO:K01466] [EC:3.5.2.5]
Caci_4725  allantoicase [KO:K01477] [EC:3.5.3.4]
Caci_6441  urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
Caci_6440  urease, beta subunit [KO:K01429] [EC:3.5.1.5]
Caci_6439  urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
Caci_1878  Carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cai00030  Pentose phosphate pathway
cai00220  Arginine biosynthesis
cai00250  Alanine, aspartate and glutamate metabolism
cai00260  Glycine, serine and threonine metabolism
cai00340  Histidine metabolism
cai00630  Glyoxylate and dicarboxylate metabolism
cai00730  Thiamine metabolism
cai00740  Riboflavin metabolism
cai00790  Folate biosynthesis
KO pathway
ko00230   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (69)   
   KEGG GENES (69)   
All databases (70)   

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