KEGG   PATHWAY: cal04140Help
Entry
cal04140                    Pathway                                

Name
Regulation of autophagy - Candida albicans
Class
Cellular Processes; Transport and catabolism
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Pathway map
Regulation of autophagy
cal04140

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BSID: 
GO: 
Organism
Candida albicans [GN:cal]
Gene
ATG1; likely protein kinase similar to S. cerevisiae ATG1 (YGL180W) protein kinase required for autophagy and cytoplasm-to-vacuole targeting [KO:K08269] [EC:2.7.11.1]
ATG1; likely protein kinase similar to S. cerevisiae ATG1 (YGL180W) protein kinase required for autophagy and cytoplasm-to-vacuole targeting [KO:K08269] [EC:2.7.11.1]
ATG17; weak similarity to S. cerevisiae ATG17 (YLR423C) activator of Atg1 protein kinase [KO:K08329]
ATG17; weak similarity to S. cerevisiae ATG17 (YLR423C) activator of Atg1 protein kinase [KO:K08329]
ATG11; similar to S. cerevisiae ATG11 (YPR049C) involved in protein-vacuolar targeting and pexophagy [KO:K08330]
ATG11; similar to S. cerevisiae ATG11 (YPR049C) involved in protein-vacuolar targeting and pexophagy [KO:K08330]
similar to S. pombe SPAC4F10.07c; K08331 autophagy-related protein 13 [KO:K08331]
similar to S. pombe SPAC4F10.07c; K08331 autophagy-related protein 13 [KO:K08331]
VAC8; vacuolar inheritance and protein targeting [KO:K08332]
VAC8; vacuolar inheritance and protein targeting [KO:K08332]
VPS15; similar to N terminal half of VPS15 protein kinase involved in vacuolar protein sorting [KO:K08333] [EC:2.7.11.1]
VPS15; similar to N terminal half of VPS15 protein kinase involved in vacuolar protein sorting [KO:K08333] [EC:2.7.11.1]
VPS30; weak similarity to VPS30, role in vacuolar protein sorting [KO:K08334]
VPS34; phosphatidylinositol 3-kinase [KO:K00914] [EC:2.7.1.137]
VPS34; phosphatidylinositol 3-kinase [KO:K00914] [EC:2.7.1.137]
ATG12; similar to S. cerevisiae ATG12 (YBR217W) which nucleates preautophagosome formation as a conjugate with Atg5 [KO:K08336]
ATG12; similar to S. cerevisiae ATG12 (YBR217W) which nucleates preautophagosome formation as a conjugate with Atg5 [KO:K08336]
ATG7; similar to S. cerevisiae ATG7 (YHR171W) protein-conjugating enzyme of the Apg12p-Apg5p conjugation pathway of autophagy [KO:K08337]
ATG7; similar to S. cerevisiae ATG7 (YHR171W) protein-conjugating enzyme of the Apg12p-Apg5p conjugation pathway of autophagy [KO:K08337]
ATG5; similar to S. cerevisiae ATG5 (YPL149W) which nucleates preautophagosome formation as a conjugate with Atg12 [KO:K08339]
ATG5; similar to S. cerevisiae ATG5 (YPL149W) which nucleates preautophagosome formation as a conjugate with Atg12 [KO:K08339]
ATG4; potential protease similar to S. cerevisiae ATG4 (YNL223W) microtubule-binding anchor protein involved in attachment of autophagosomes to microtubules. [KO:K08342] [EC:3.4.22.-]
ATG4; potential protease similar to S. cerevisiae ATG4 (YNL223W) microtubule-binding anchor protein involved in attachment of autophagosomes to microtubules. [KO:K08342] [EC:3.4.22.-]
ATG3; similar to S. cerevisiae ATG3 (YNR007C) part of ubiquitin-like system that mediates Atg8-phosphatidylethanolamine conjugation required for protein-vacuolar targeting and autophagy [KO:K08343] [EC:6.3.2.19]
ATG3; similar to S. cerevisiae ATG3 (YNR007C) part of ubiquitin-like system that mediates Atg8-phosphatidylethanolamine conjugation required for protein-vacuolar targeting and autophagy [KO:K08343] [EC:6.3.2.19]
Compound
C00350  
Phosphatidylethanolamine
C00913  
3-Methyladenine
C01194  
1-Phosphatidyl-D-myo-inositol
C04549  
1-Phosphatidyl-1D-myo-inositol 3-phosphate
C15181  
Wortmannin
Reference
  Authors
Meijer AJ, Codogno P.
  Title
Regulation and role of autophagy in mammalian cells.
  Journal
Int J Biochem Cell Biol 36:2445-62 (2004)
Reference
  Authors
Deretic V.
  Title
Autophagy in innate and adaptive immunity.
  Journal
Trends Immunol 26:523-8 (2005)
Reference
  Authors
Thompson AR, Vierstra RD.
  Title
Autophagic recycling: lessons from yeast help define the process in plants.
  Journal
Curr Opin Plant Biol 8:165-73 (2005)
Reference
  Authors
Levine B, Yuan J.
  Title
Autophagy in cell death: an innocent convict?
  Journal
J Clin Invest 115:2679-88 (2005)
Reference
  Authors
Tanida I, Ueno T, Kominami E.
  Title
LC3 conjugation system in mammalian autophagy.
  Journal
Int J Biochem Cell Biol 36:2503-18 (2004)
Reference
  Authors
Lum JJ, DeBerardinis RJ, Thompson CB.
  Title
Autophagy in metazoans: cell survival in the land of plenty.
  Journal
Nat Rev Mol Cell Biol 6:439-48 (2005)
Reference
  Authors
Reggiori F, Klionsky DJ.
  Title
Autophagosomes: biogenesis from scratch?
  Journal
Curr Opin Cell Biol 17:415-22 (2005)
Reference
  Authors
Klionsky DJ, Emr SD.
  Title
Autophagy as a regulated pathway of cellular degradation.
  Journal
Science 290:1717-21 (2000)
Reference
  Authors
Bechet D, Tassa A, Taillandier D, Combaret L, Attaix D.
  Title
Lysosomal proteolysis in skeletal muscle.
  Journal
Int J Biochem Cell Biol 37:2098-114 (2005)
KO pathway
 

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