KEGG   PATHWAY: cay00230
Entry
cay00230                    Pathway                                
Name
Purine metabolism - Clostridium acetobutylicum EA 2018
Class
Metabolism; Nucleotide metabolism
Pathway map
cay00230  Purine metabolism
cay00230

Module
cay_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cay00230]
cay_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cay00230]
cay_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cay00230]
cay_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cay00230]
cay_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cay00230]
Other DBs
GO: 0006163 0042278
Organism
Clostridium acetobutylicum EA 2018 [GN:cay]
Gene
CEA_G3608  Nudix (MutT) family hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
CEA_G1867  Nudix (MutT) family hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
CEA_G2079  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
CEA_G2351  Phosphomannomutase [KO:K01835] [EC:5.4.2.2]
CEA_G3225  prs; Phosphoribosylpyrophosphate synthetase [KO:K00948] [EC:2.7.6.1]
CEA_G0830  phosphoribosylpyrophosphate synthetase [KO:K00948] [EC:2.7.6.1]
CEA_G1407  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
CEA_G1411  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
CEA_G1409  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
CEA_G1668  purQ; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) [KO:K01952] [EC:6.3.5.3]
CEA_G1408  purM; phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
CEA_G1405  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
CEA_G1406  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
CEA_G1834  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
CEA_G1410  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
CEA_G2459  5-aminoimidazole-4-carboxamide ribonucleotide transformylase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
CEA_G2290  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
CEA_G2078  deoD; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
CEA_G1712  Conserved hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
CEA_G3207  hprT; Hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
CEA_G2709  guaB; inositol-5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
CEA_G1008  ndk; putative nucleoside-diphosphate kinase N-terminal domain protein [KO:K00940] [EC:2.7.4.6]
CEA_G2674  putative deoxyribonucleotide triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
CEA_G0885  xpt; xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
CEA_G2708  guaA; bifunctional GMP synthase/glutamine amidotransferase protein [KO:K01951] [EC:6.3.5.2]
CEA_G3475  guanosine 5'-monophosphate oxidoreductase [KO:K00364] [EC:1.7.1.7]
CEA_G0289  Cytosine/guanine deaminase related protein [KO:K01487] [EC:3.5.4.3]
CEA_G1731  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
CEA_G1229  Guanylate kinase (P-loop type) [KO:K00942] [EC:2.7.4.8]
CEA_G1059  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
CEA_G3279  nrdA; ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
CEA_G3278  nrdF; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
CEA_G0491  nrdD; anaerobic ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
CEA_G1221  anaerobic ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
CEA_G2289  spoT; RelA/SpoT protein, (p)ppGpp synthetase/pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CEA_G0633  Exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CEA_G0654  Conserved hypothetical protein [KO:K07816] [EC:2.7.6.5]
CEA_G3343  Conserved hypothetical protein [KO:K07816] [EC:2.7.6.5]
CEA_G0662  Adenilate cyclase, class2 (thermophilic) [KO:K05873] [EC:4.6.1.1]
CEA_G3600  purA; Adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
CEA_G3011  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
CEA_G0899  adeC; Adenine deaminase [KO:K01486] [EC:3.5.4.2]
CEA_G1980  5'-nucleotidase/2',3'-cyclic phosphodiesterase related enzyme [KO:K01119] [EC:3.1.4.16 3.1.3.6]
CEA_G0363  2,3-cyclic-nucleotide 2'phosphodiesterase (duplication) [KO:K08693] [EC:3.1.4.16 3.1.3.6 3.1.3.5]
CEA_G3117  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
CEA_G0104  cysC; Adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
CEA_G0111  cysN; GTPase, sulfate adenylate transferase subunit 1 [KO:K00956] [EC:2.7.7.4]
CEA_G0110  cysD; Sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cay00030  Pentose phosphate pathway
cay00220  Arginine biosynthesis
cay00250  Alanine, aspartate and glutamate metabolism
cay00260  Glycine, serine and threonine metabolism
cay00340  Histidine metabolism
cay00630  Glyoxylate and dicarboxylate metabolism
cay00730  Thiamine metabolism
cay00740  Riboflavin metabolism
cay00790  Folate biosynthesis
KO pathway
ko00230   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (48)   
   KEGG GENES (48)   
All databases (49)   

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