KEGG   PATHWAY: cfa00100Help
Entry
cfa00100                    Pathway                                

Name
Steroid biosynthesis - Canis familiaris (dog)
Class
Metabolism; Lipid metabolism
BRITE hierarchy
Pathway map
cfa00100  Steroid biosynthesis
cfa00100

Ortholog table
Module
cfa_M00101  Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol [PATH:cfa00100]
cfa_M00103  Cholecalciferol biosynthesis [PATH:cfa00100]
Other DBs
BSID: 83984
GO: 0016126
Organism
Canis familiaris (dog) [GN:cfa]
Gene
477362  FDFT1; farnesyl-diphosphate farnesyltransferase 1 [KO:K00801] [EC:2.5.1.21]
608021  SQLE; squalene epoxidase [KO:K00511] [EC:1.14.14.17]
491611  LSS; lanosterol synthase [KO:K01852] [EC:5.4.99.7]
475225  CYP51A1; cytochrome P450, family 51, subfamily A, polypeptide 1 [KO:K05917] [EC:1.14.13.70]
476027  TM7SF2; transmembrane 7 superfamily member 2 [KO:K00222] [EC:1.3.1.70]
475491  MSMO1; methylsterol monooxygenase 1 [KO:K07750] [EC:1.14.18.9]
481079  NSDHL; NAD(P) dependent steroid dehydrogenase-like [KO:K07748] [EC:1.1.1.170]
609364  HSD17B7; hydroxysteroid 17-beta dehydrogenase 7 [KO:K13373] [EC:1.1.1.270 1.1.1.62]
609430  EBP; emopamil binding protein (sterol isomerase) [KO:K01824] [EC:5.3.3.5]
489573  DHCR24; 24-dehydrocholesterol reductase [KO:K09828] [EC:1.3.1.- 1.3.1.72]
610411  SC5D; sterol-C5-desaturase [KO:K00227] [EC:1.14.19.20]
483675  DHCR7; 7-dehydrocholesterol reductase [KO:K00213] [EC:1.3.1.21]
100856363  LIPA; lipase A, lysosomal acid type [KO:K01052] [EC:3.1.1.13]
491280  CEL; carboxyl ester lipase [KO:K12298] [EC:3.1.1.3 3.1.1.13]
490325  SOAT1; sterol O-acyltransferase 1 [KO:K00637] [EC:2.3.1.26]
486511  SOAT2; sterol O-acyltransferase 2 [KO:K00637] [EC:2.3.1.26]
612993  CYP2R1; cytochrome P450, family 2, subfamily R, polypeptide 1 [KO:K07419] [EC:1.14.14.24]
481133  CYP27B1; cytochrome P450, family 27, subfamily B, polypeptide 1 [KO:K07438] [EC:1.14.15.18]
485935  CYP24A1; cytochrome P450, family 24, subfamily A, polypeptide 1 [KO:K07436] [EC:1.14.15.16]
Compound
C00187  Cholesterol
C00448  trans,trans-Farnesyl diphosphate
C00751  Squalene
C01054  (S)-2,3-Epoxysqualene
C01164  7-Dehydrocholesterol
C01189  Lathosterol
C01561  Calcidiol
C01673  Calcitriol
C01694  Ergosterol
C01724  Lanosterol
C01753  beta-Sitosterol
C01789  Campesterol
C01802  Desmosterol
C01902  Cycloartenol
C01943  Obtusifoliol
C02141  Cycloeucalenol
C02530  Cholesterol ester
C03428  Presqualene diphosphate
C03845  5alpha-Cholest-8-en-3beta-ol
C04525  Fecosterol
C05103  4alpha-Methylzymosterol
C05107  7-Dehydrodesmosterol
C05108  14-Demethyllanosterol
C05109  24,25-Dihydrolanosterol
C05437  Zymosterol
C05439  5alpha-Cholesta-7,24-dien-3beta-ol
C05440  Ergosta-5,7,22,24(28)-tetraen-3beta-ol
C05441  Vitamin D2
C05442  Stigmasterol
C05443  Vitamin D3
C07712  Secalciferol
C08813  Brassicasterol
C08821  Isofucosterol
C08830  24-Methylenecycloartanol
C11455  4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
C11508  4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol
C11522  24-Methylenelophenol
C11523  24-Ethylidenelophenol
C15776  4alpha-Methylfecosterol
C15777  Episterol
C15778  5,7,24(28)-Ergostatrienol
C15780  5-Dehydroepisterol
C15781  24-Methylenecholesterol
C15782  Delta7-Avenasterol
C15783  5-Dehydroavenasterol
C15808  4alpha-Methylzymosterol-4-carboxylate
C15816  3-Keto-4-methylzymosterol
C15915  4,4-Dimethyl-5alpha-cholesta-8-en-3beta-ol
C18231  Calcitetrol
C21106  24-epi-Campesterol
Reference
  Authors
Koshiba K, Kamiya Y.
  Title
[Atarasii Syokubutuhorumon no Kagaku] (In Japanese)
  Journal
Koudansya saientific:199-138 (2002)
Reference
  Authors
Morikawa T, Mizutani M, Aoki N, Watanabe B, Saga H, Saito S, Oikawa A, Suzuki H, Sakurai N, Shibata D, Wadano A, Sakata K, Ohta D.
  Title
Cytochrome P450 CYP710A encodes the sterol C-22 desaturase in Arabidopsis and tomato.
  Journal
Plant Cell 18:1008-22 (2006)
DOI:10.1105/tpc.105.036012
Reference
  Authors
Lange BM, Ghassemian M.
  Title
Genome organization in Arabidopsis thaliana: a survey for genes involved in isoprenoid and chlorophyll metabolism.
  Journal
Plant Mol Biol 51:925-48 (2003)
DOI:10.1023/A:1023005504702
KO pathway
ko00100   

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