KEGG   PATHWAY: cfa00250
Entry
cfa00250                    Pathway                                
Name
Alanine, aspartate and glutamate metabolism - Canis lupus familiaris (dog)
Class
Metabolism; Amino acid metabolism
Pathway map
cfa00250  Alanine, aspartate and glutamate metabolism
cfa00250

Module
cfa_M00027  GABA (gamma-Aminobutyrate) shunt [PATH:cfa00250]
Other DBs
GO: 0006522 0006531 0006536
Organism
Canis lupus familiaris (dog) [GN:cfa]
Gene
486834  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
475591  GOT1L1; putative aspartate aminotransferase, cytoplasmic 2 isoform X2 [KO:K14454] [EC:2.6.1.1]
478103  GOT2; aspartate aminotransferase, mitochondrial isoform X1 [KO:K14455] [EC:2.6.1.1]
484371  IL4I1; L-amino-acid oxidase isoform X1 [KO:K03334] [EC:1.4.3.2]
482436  L-amino-acid oxidase-like [KO:K03334] [EC:1.4.3.2]
483789  ASRGL1; isoaspartyl peptidase/L-asparaginase isoform X1 [KO:K13051] [EC:3.5.1.1 3.4.19.5]
475240  ASNS; asparagine synthetase [glutamine-hydrolyzing] [KO:K01953] [EC:6.3.5.4]
478540  NIT2; omega-amidase NIT2 [KO:K13566] [EC:3.5.1.3]
609510  GPT2; alanine aminotransferase 2 [KO:K00814] [EC:2.6.1.2]
609914  GPT; alanine aminotransferase 1 isoform X1 [KO:K00814] [EC:2.6.1.2]
100855679  AGXT; serine--pyruvate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
612589  AGXT2; alanine--glyoxylate aminotransferase 2, mitochondrial isoform X2 [KO:K00827] [EC:2.6.1.44 2.6.1.40]
480693  ASS1; argininosuccinate synthase [KO:K01940] [EC:6.3.4.5]
479704  ASL; argininosuccinate lyase isoform X2 [KO:K01755] [EC:4.3.2.1]
480098  ADSS2; adenylosuccinate synthetase isozyme 2 isoform X1 [KO:K01939] [EC:6.3.4.4]
612692  ADSS1; adenylosuccinate synthetase isozyme 1 [KO:K01939] [EC:6.3.4.4]
474499  ADSL; adenylosuccinate lyase isoform X2 [KO:K01756] [EC:4.3.2.2]
612955  NAT8L; N-acetylaspartate synthetase [KO:K18309] [EC:2.3.1.17]
486698  RIMKLB; beta-citrylglutamate synthase B isoform X1 [KO:K18310] [EC:6.3.1.17 6.3.2.41]
482445  RIMKLA; N-acetylaspartylglutamate synthase A isoform X2 [KO:K18311] [EC:6.3.2.41 6.3.2.42]
476775  FOLH1; glutamate carboxypeptidase 2 [KO:K14592] [EC:3.4.17.21]
611064  ASPA; aspartoacylase isoform X2 [KO:K01437] [EC:3.5.1.15]
487107  GAD2; glutamate decarboxylase 2 [KO:K01580] [EC:4.1.1.15]
478794  GAD1; glutamate decarboxylase 1 [KO:K01580] [EC:4.1.1.15]
483960  glutamate decarboxylase 1-like [KO:K01580] [EC:4.1.1.15]
479856  ABAT; 4-aminobutyrate aminotransferase, mitochondrial [KO:K13524] [EC:2.6.1.19 2.6.1.22]
488246  ALDH5A1; succinate-semialdehyde dehydrogenase, mitochondrial [KO:K00139] [EC:1.2.1.24]
100684847  GLUD1; glutamate dehydrogenase 1, mitochondrial [KO:K00261] [EC:1.4.1.3]
612452  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial isoform X1 [KO:K00294] [EC:1.2.1.88]
403443  GLUL; glutamine synthetase isoform 2 [KO:K01915] [EC:6.3.1.2]
612295  LOW QUALITY PROTEIN: glutamine synthetase-like [KO:K01915] [EC:6.3.1.2]
483009  CAD; CAD protein isoform X1 [KO:K11540] [EC:6.3.5.5 2.1.3.2 3.5.2.3]
488448  GLS; LOW QUALITY PROTEIN: glutaminase kidney isoform, mitochondrial isoform X2 [KO:K01425] [EC:3.5.1.2]
100686499  GLS2; glutaminase liver isoform, mitochondrial isoform X1 [KO:K01425] [EC:3.5.1.2]
488506  CPS1; carbamoyl-phosphate synthase [ammonia], mitochondrial [KO:K01948] [EC:6.3.4.16]
474624  GFPT1; glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 isoform X1 [KO:K00820] [EC:2.6.1.16]
474653  GFPT2; glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 [KO:K00820] [EC:2.6.1.16]
611407  PPAT; amidophosphoribosyltransferase isoform X2 [KO:K00764] [EC:2.4.2.14]
Compound
C00014  Ammonia
C00022  Pyruvate
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00036  Oxaloacetate
C00041  L-Alanine
C00042  Succinate
C00049  L-Aspartate
C00064  L-Glutamine
C00122  Fumarate
C00152  L-Asparagine
C00158  Citrate
C00169  Carbamoyl phosphate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00352  D-Glucosamine 6-phosphate
C00402  D-Aspartate
C00438  N-Carbamoyl-L-aspartate
C00940  2-Oxoglutaramate
C01042  N-Acetyl-L-aspartate
C02362  2-Oxosuccinamate
C03090  5-Phosphoribosylamine
C03406  N-(L-Arginino)succinate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03912  (S)-1-Pyrroline-5-carboxylate
C12270  N-Acetylaspartylglutamate
C20775  beta-Citryl-L-glutamate
C20776  N-Acetylaspartylglutamylglutamate
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
PMID:9687539
  Authors
Wu G
  Title
Intestinal mucosal amino acid catabolism.
  Journal
J Nutr 128:1249-52 (1998)
DOI:10.1093/jn/128.8.1249
Related
pathway
cfa00010  Glycolysis / Gluconeogenesis
cfa00020  Citrate cycle (TCA cycle)
cfa00220  Arginine biosynthesis
cfa00230  Purine metabolism
cfa00240  Pyrimidine metabolism
cfa00260  Glycine, serine and threonine metabolism
cfa00330  Arginine and proline metabolism
cfa00340  Histidine metabolism
cfa00410  beta-Alanine metabolism
cfa00470  D-Amino acid metabolism
cfa00480  Glutathione metabolism
cfa00520  Amino sugar and nucleotide sugar metabolism
cfa00620  Pyruvate metabolism
cfa00630  Glyoxylate and dicarboxylate metabolism
cfa00650  Butanoate metabolism
cfa00760  Nicotinate and nicotinamide metabolism
cfa00770  Pantothenate and CoA biosynthesis
cfa00860  Porphyrin metabolism
cfa00910  Nitrogen metabolism
KO pathway
ko00250   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (38)   
   KEGG GENES (38)   
All databases (39)   

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