KEGG PATHWAY: ckl00230

PATHWAY: ckl00230

Entry

ckl00230 Pathway

Name

Purine metabolism - Clostridium kluyveri DSM 555

Class

Metabolism; Nucleotide metabolism

Pathway map

ckl00230

Purine metabolism

Module

ckl_M00005	PRPP biosynthesis, ribose 5P => PRPP [PATH:ckl00230]
ckl_M00048	Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:ckl00230]
ckl_M00049	Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ckl00230]
ckl_M00050	Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:ckl00230]
ckl_M00546	Purine degradation, xanthine => urea [PATH:ckl00230]

Other DBs

BSID:

55624

GO:

0042278

Organism

Clostridium kluyveri DSM 555 [GN:ckl]

Gene

CKL_1238	ADP-ribose pyrophosphatase; K01515 ADP-ribose pyrophosphatase [EC:3.6.1.13] [KO:K01515] [EC:3.6.1.13]
CKL_2911	hydrolase; K01515 ADP-ribose pyrophosphatase [EC:3.6.1.13] [KO:K01515] [EC:3.6.1.13]
CKL_1242	deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
CKL_3180	pgm2; protein Pgm2 [KO:K01835] [EC:5.4.2.2]
CKL_0798	pgm1; protein Pgm1 [KO:K01835] [EC:5.4.2.2]
CKL_0147	prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
CKL_2687	purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
CKL_2683	purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
CKL_2685	purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
CKL_1286	purL; hypothetical protein [KO:K01952] [EC:6.3.5.3]
CKL_2686	purM; phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
CKL_2689	purE; hypothetical protein [KO:K01588] [EC:5.4.99.18]
CKL_2688	purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
CKL_1454	purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
CKL_2684	purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:3.5.4.10 2.1.2.3]
CKL_3132	apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
CKL_0997	surE; stationary phase survival protein SurE [KO:K03787] [EC:3.1.3.5]
CKL_1608	punA; protein PunA [KO:K03783] [EC:2.4.2.1]
CKL_0171	hpt; hypothetical protein [KO:K00760] [EC:2.4.2.8]
CKL_0465	guaB; inosine 5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
CKL_1625	ndk; hypothetical protein [KO:K00940] [EC:2.7.4.6]
CKL_3463	deoxyribonucleotide triphosphate pyrophosphatase; K02428 dITP/XTP pyrophosphatase [EC:3.6.1.19] [KO:K02428] [EC:3.6.1.19]
CKL_0466	guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
CKL_2842	gmk; hypothetical protein [KO:K00942] [EC:2.7.4.8]
CKL_1365	gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
CKL_3558	pyk; hypothetical protein [KO:K00873] [EC:2.7.1.40]
CKL_3757	nrdD; anaerobic ribonucleoside triphosphate reductase [KO:K00527] [EC:1.17.4.2]
CKL_0940	deoxyguanosinetriphosphate triphosphohydrolase-like protein; K01129 dGTPase [EC:3.1.5.1] [KO:K01129] [EC:3.1.5.1]
CKL_0252	rpoA; DNA-directed RNA polymerase subunit alpha [KO:K03040] [EC:2.7.7.6]
CKL_0216	rpoB; DNA-directed RNA polymerase subunit beta [KO:K03043] [EC:2.7.7.6]
CKL_0217	rpoC; DNA-directed RNA polymerase subunit beta' [KO:K03046] [EC:2.7.7.6]
CKL_1366	rpoZ; DNA-directed RNA polymerase subunit omega [KO:K03060] [EC:2.7.7.6]
CKL_0669	polA; DNA polymerase I [KO:K02335] [EC:2.7.7.7]
CKL_3560	dnaE; DNA polymerase III DnaE [KO:K02337] [EC:2.7.7.7]
CKL_1426	polC; DNA polymerase III PolC [KO:K03763] [EC:2.7.7.7]
CKL_0002	dnaN; DNA polymerase III subunit beta [KO:K02338] [EC:2.7.7.7]
CKL_3827	dnaX; DNA polymerase III subunits gamma and tau [KO:K02343] [EC:2.7.7.7]
CKL_0893	holA; DNA polymerase III subunit delta [KO:K02340] [EC:2.7.7.7]
CKL_3793	DNA polymerase III subunit delta'; K02341 DNA polymerase III subunit delta' [EC:2.7.7.7] [KO:K02341] [EC:2.7.7.7]
CKL_4034	DNA polymerase III subunit epsilon; K02342 DNA polymerase III subunit epsilon [EC:2.7.7.7] [KO:K02342] [EC:2.7.7.7]
CKL_2254	ppx2; protein Ppx2 [KO:K01524] [EC:3.6.1.40 3.6.1.11]
CKL_2253	ppx1; hypothetical protein [KO:K01524] [EC:3.6.1.40 3.6.1.11]
CKL_3131	relA; RelA protein [KO:K00951] [EC:2.7.6.5]
CKL_3606	hypothetical protein; K07816 putative GTP pyrophosphokinase [EC:2.7.6.5] [KO:K07816] [EC:2.7.6.5]
CKL_3600	hypothetical protein; K05873 adenylate cyclase, class 2 [EC:4.6.1.1] [KO:K05873] [EC:4.6.1.1]
CKL_0087	purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
CKL_0833	add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
CKL_0245	adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
CKL_1437	pnp; polynucleotide phosphorylase/polyadenylase [KO:K00962] [EC:2.7.7.8]
CKL_1799	cysC; hypothetical protein [KO:K00860] [EC:2.7.1.25]
CKL_1795	cysN; protein CysN [KO:K00956] [EC:2.7.7.4]
CKL_1796	cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]

Compound

C00002	ATP
C00008	ADP
C00011	CO2
C00014	Ammonia
C00020	AMP
C00035	GDP
C00037	Glycine
C00039	DNA
C00044	GTP
C00046	RNA
C00048	Glyoxylate
C00053	3'-Phosphoadenylyl sulfate
C00054	Adenosine 3',5'-bisphosphate
C00059	Sulfate
C00064	L-Glutamine
C00081	ITP
C00086	Urea
C00104	IDP
C00117	D-Ribose 5-phosphate
C00119	5-Phospho-alpha-D-ribose 1-diphosphate
C00130	IMP
C00131	dATP
C00144	GMP
C00147	Adenine
C00169	Carbamoyl phosphate
C00206	dADP
C00212	Adenosine
C00224	Adenylyl sulfate
C00242	Guanine
C00262	Hypoxanthine
C00286	dGTP
C00294	Inosine
C00301	ADP-ribose
C00330	Deoxyguanosine
C00360	dAMP
C00361	dGDP
C00362	dGMP
C00366	Urate
C00385	Xanthine
C00387	Guanosine
C00499	Allantoate
C00559	Deoxyadenosine
C00575	3',5'-Cyclic AMP
C00603	(-)-Ureidoglycolate
C00620	alpha-D-Ribose 1-phosphate
C00655	Xanthosine 5'-phosphate
C00700	XTP
C00802	Oxalureate
C00942	3',5'-Cyclic GMP
C01228	Guanosine 3',5'-bis(diphosphate)
C01260	P1,P4-Bis(5'-adenosyl) tetraphosphate
C01261	P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344	dIDP
C01345	dITP
C01367	3'-AMP
C01762	Xanthosine
C02091	(S)-Ureidoglycine
C02348	(R)(-)-Allantoin
C02350	(S)(+)-Allantoin
C02353	2',3'-Cyclic AMP
C02718	N-Formiminoglycine
C03090	5-Phosphoribosylamine
C03373	Aminoimidazole ribotide
C03483	Adenosine tetraphosphate
C03614	Inosine 5'-tetraphosphate
C03794	N6-(1,2-Dicarboxyethyl)-AMP
C03838	5'-Phosphoribosylglycinamide
C04051	5-Amino-4-imidazolecarboxyamide
C04376	5'-Phosphoribosyl-N-formylglycinamide
C04392	P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494	Guanosine 3'-diphosphate 5'-triphosphate
C04640	2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677	1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734	1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751	1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823	1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239	5-Aminoimidazole
C05512	Deoxyinosine
C05513	Urate-3-ribonucleoside
C05515	5-Ureido-4-imidazole carboxylate
C05516	5-Amino-4-imidazole carboxylate
C05993	Acetyl adenylate
C06193	Guanosine 3'-phosphate
C06194	2',3'-Cyclic GMP
C06195	Imidazolone
C06196	2'-Deoxyinosine 5'-phosphate
C06197	P1,P3-Bis(5'-adenosyl) triphosphate
C06433	5'-Benzoylphosphoadenosine
C06435	5'-Butyrylphosphoinosine
C11821	5-Hydroxyisourate
C12248	5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667	5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole

Reference

PMID:10601204

Authors

Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.

Title

Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.

Journal

J Bacteriol 181:7479-84 (1999)

Reference

PMID:10986234

Authors

Xi H, Schneider BL, Reitzer L.

Title

Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.

Journal

J Bacteriol 182:5332-41 (2000)

KO pathway

ko00230

All links

Pathway (4)   
   KEGG MODULE (3)   
   BioSystems (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (52)   
   KEGG GENES (52)   
All databases (57)   

Download RDF

DBGET integrated database retrieval system