KEGG   PATHWAY: cro00230
Entry
cro00230                    Pathway                                
Name
Purine metabolism - Citrobacter rodentium
Class
Metabolism; Nucleotide metabolism
Pathway map
cro00230  Purine metabolism
cro00230

Module
cro_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cro00230]
cro_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cro00230]
cro_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cro00230]
cro_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cro00230]
cro_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cro00230]
cro_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:cro00230]
Other DBs
GO: 0006163 0042278
Organism
Citrobacter rodentium [GN:cro]
Gene
ROD_35811  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
ROD_44261  nudE; ADP compounds hydrolase [KO:K08312] [EC:3.6.1.-]
ROD_49061  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
ROD_06961  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
ROD_18061  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
ROD_27231  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
ROD_37471  purD; phosphoribosylglycineamide synthetase [KO:K01945] [EC:6.3.4.13]
ROD_24431  purN; phosphoribosylglycinamide formyltransferase 1 [KO:K11175] [EC:2.1.2.2]
ROD_18891  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
ROD_25001  purL; Phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
ROD_24421  purM; phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
ROD_05541  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
ROD_05551  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
ROD_24251  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
ROD_12211  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
ROD_37461  purH; bifunctional purine biosynthesis protein [includes phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase] [KO:K00602] [EC:2.1.2.3 3.5.4.10]
ROD_05271  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
ROD_05381  ushA; protein UshA precursor [KO:K11751] [EC:3.1.3.5 3.6.1.45]
ROD_30651  surE; multifunctional stationary-phase survival protein [includes: 5'/3'-nucleotidase; exopolyphosphatase] [KO:K03787] [EC:3.1.3.5 3.1.3.6]
ROD_06771  nagD; putative N-acetylglucosamine metabolism protein [KO:K02566] [EC:3.1.3.5]
ROD_44241  putative hydrolase [KO:K20881] [EC:3.1.3.-]
ROD_05351  gsk; inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
ROD_49071  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
ROD_04361  conserved hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
ROD_25351  conserved hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
ROD_01371  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
ROD_24491  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
ROD_24611  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
ROD_50811  conserved hypothetical protein [KO:K01529] [EC:3.6.1.73]
ROD_50321  conserved hypothetical protein [KO:K01519] [EC:3.6.1.66]
ROD_03331  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
ROD_03851  putative xanthine dehydrogenase,molybdenum-binding subunit [KO:K11177] [EC:1.17.1.4]
ROD_03861  putative xanthine dehydrogenase, FAD-binding subunit [KO:K11178] [EC:1.17.1.4]
ROD_03871  putative xanthine dehydrogenase iron-sulfur-binding subunit [KO:K13483]
ROD_24481  guaA; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
ROD_01091  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
ROD_41681  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
ROD_23551  nrdA; ribonucleoside-diphosphate reductase 1 alpha chain [KO:K00525] [EC:1.17.4.1]
ROD_31331  nrdE; ribonucleoside-diphosphate reductase 2 alpha chain [KO:K00525] [EC:1.17.4.1]
ROD_23561  nrdB; ribonucleoside-diphosphate reductase 1 beta chain [KO:K00526] [EC:1.17.4.1]
ROD_31321  nrdF; ribonucleoside-diphosphate reductase 2 beta chain [KO:K00526] [EC:1.17.4.1]
ROD_33091  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
ROD_01641  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
ROD_26931  5'-nucleotidase [KO:K08722] [EC:3.1.3.89]
ROD_26251  hypothetical prophage protein [KO:K06952] [EC:3.1.3.89]
ROD_41661  spoT; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
ROD_24451  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
ROD_39681  gppA; guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
ROD_30321  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
ROD_39451  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
ROD_32371  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
ROD_14461  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
ROD_20941  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
ROD_28351  putative decarboxylase [KO:K06966] [EC:3.2.2.10 3.2.2.-]
ROD_32681  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
ROD_05321  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
ROD_30331  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
ROD_35791  icc; putative phosphoesterase [KO:K03651] [EC:3.1.4.53]
ROD_00561  apaH; bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
ROD_30591  cysC; adenosine 5-phosphosulfate kinase [KO:K00860] [EC:2.7.1.25]
ROD_30581  cysN; Sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
ROD_30571  cysD; Sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
ROD_50451  transthyretin-like protein [KO:K07127] [EC:3.5.2.17]
ROD_36121  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
ROD_36111  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
ROD_36101  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
ROD_33991  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
ROD_50691  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cro00030  Pentose phosphate pathway
cro00220  Arginine biosynthesis
cro00250  Alanine, aspartate and glutamate metabolism
cro00260  Glycine, serine and threonine metabolism
cro00340  Histidine metabolism
cro00630  Glyoxylate and dicarboxylate metabolism
cro00730  Thiamine metabolism
cro00740  Riboflavin metabolism
cro00790  Folate biosynthesis
KO pathway
ko00230   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (68)   
   KEGG GENES (68)   
All databases (69)   

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