KEGG   PATHWAY: dpo00564
Entry
dpo00564                    Pathway                                
Name
Glycerophospholipid metabolism - Drosophila pseudoobscura
Class
Metabolism; Lipid metabolism
Pathway map
dpo00564  Glycerophospholipid metabolism
dpo00564

Module
dpo_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:dpo00564]
Other DBs
GO: 0006650
Organism
Drosophila pseudoobscura [GN:dpo]
Gene
4803724  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
6903339  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic isoform X1 [KO:K00006] [EC:1.1.1.8]
4804911  glycerol-3-phosphate dehydrogenase, mitochondrial [KO:K00111] [EC:1.1.5.3]
4805720  glycerol-3-phosphate dehydrogenase, mitochondrial [KO:K00111] [EC:1.1.5.3]
4818127  glycerol-3-phosphate dehydrogenase, mitochondrial [KO:K00111] [EC:1.1.5.3]
4801106  glycerol-3-phosphate acyltransferase 1, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
4804315  glycerol-3-phosphate acyltransferase 3-like isoform X3 [KO:K13506] [EC:2.3.1.15]
4815349  glycerol-3-phosphate acyltransferase 3 [KO:K13506] [EC:2.3.1.15]
4815155  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha [KO:K13509] [EC:2.3.1.51]
4812416  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
4804082  lysophospholipid acyltransferase 1 isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
4802414  dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]
4812629  putative phosphatidate phosphatase [KO:K01080] [EC:3.1.3.4]
4812264  putative phosphatidate phosphatase [KO:K01080] [EC:3.1.3.4]
4812249  putative phosphatidate phosphatase [KO:K01080] [EC:3.1.3.4]
4812580  putative phosphatidate phosphatase [KO:K01080] [EC:3.1.3.4]
4812480  putative phosphatidate phosphatase [KO:K01080] [EC:3.1.3.4]
4804520  putative phosphatidate phosphatase isoform X1 [KO:K01080] [EC:3.1.3.4]
6898511  putative phosphatidate phosphatase isoform X1 [KO:K01080] [EC:3.1.3.4]
4804337  phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
4802427  phospholipid phosphatase 5 isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
4801746  diacylglycerol kinase theta isoform X1 [KO:K00901] [EC:2.7.1.107]
4805461  diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
6901607  eye-specific diacylglycerol kinase isoform X19 [KO:K00901] [EC:2.7.1.107]
6897879  diacylglycerol kinase eta isoform X6 [KO:K00901] [EC:2.7.1.107]
4805011  diacylglycerol kinase 1 isoform X2 [KO:K00901] [EC:2.7.1.107]
4805577  phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
4818182  phospholipase D3 [KO:K16860] [EC:3.1.4.4]
4818185  phospholipase D3 [KO:K16860] [EC:3.1.4.4]
4803499  phospholipase A2 [KO:K01047] [EC:3.1.1.4]
4803500  phospholipase A2 large subunit [KO:K01047] [EC:3.1.1.4]
4813354  group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
4815231  acidic phospholipase A2 PA4 [KO:K01047] [EC:3.1.1.4]
6896762  uncharacterized protein LOC6896762 [KO:K01047] [EC:3.1.1.4]
4815280  uncharacterized protein LOC4815280 isoform X1 [KO:K01047] [EC:3.1.1.4]
6900734  85/88 kDa calcium-independent phospholipase A2 isoform X1 [KO:K16343] [EC:3.1.1.4]
4816052  lysophosphatidylcholine acyltransferase [KO:K13510] [EC:2.3.1.23 2.3.1.67]
4811983  lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
6903581  lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
4816647  group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
4812911  acyl-protein thioesterase 1 isoform X3 [KO:K06130] [EC:3.1.1.5]
6901966  neuropathy target esterase sws isoform X4 [KO:K14676] [EC:3.1.1.5]
4817318  glycerophosphocholine phosphodiesterase GPCPD1 [KO:K18695] [EC:3.1.4.2]
4802613  glycerophosphocholine phosphodiesterase GPCPD1 [KO:K18695] [EC:3.1.4.2]
4801339  choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
4803137  venom carboxylesterase-6 [KO:K01049] [EC:3.1.1.7]
4817085  venom carboxylesterase-6 [KO:K01049] [EC:3.1.1.7]
6898305  esterase B1 [KO:K01049] [EC:3.1.1.7]
4801388  acetylcholinesterase isoform X1 [KO:K01049] [EC:3.1.1.7]
4817935  choline/ethanolamine kinase isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
4813441  choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]
6900562  choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]
6900864  choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]
4817278  ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
4818055  ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
4815030  ethanolamine kinase [KO:K00894] [EC:2.7.1.82]
6902643  ethanolamine-phosphate cytidylyltransferase isoform X2 [KO:K00967] [EC:2.7.7.14]
6901500  alanine--glyoxylate aminotransferase 2-like [KO:K14286] [EC:4.2.3.2]
4814164  phosphatidate cytidylyltransferase, photoreceptor-specific [KO:K00981] [EC:2.7.7.41]
4812084  phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
4801761  phosphatidylserine decarboxylase proenzyme, mitochondrial [KO:K01613] [EC:4.1.1.65]
4801336  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial [KO:K00995] [EC:2.7.8.5]
4802666  probable cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
4804755  tafazzin homolog isoform X2 [KO:K13511] [EC:2.3.1.-]
4815787  CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
dpo00010  Glycolysis / Gluconeogenesis
dpo00260  Glycine, serine and threonine metabolism
dpo00561  Glycerolipid metabolism
dpo00562  Inositol phosphate metabolism
dpo00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
dpo00565  Ether lipid metabolism
dpo00620  Pyruvate metabolism
KO pathway
ko00564   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (65)   
   KEGG GENES (65)   
All databases (66)   

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