KEGG   PATHWAY: dra00230Help
Entry
dra00230                    Pathway                                

Name
Purine metabolism - Deinococcus radiodurans
Class
Metabolism; Nucleotide metabolism
BRITE hierarchy
Pathway map
Purine metabolism
dra00230

All organismsOrtholog table
Module
PRPP biosynthesis, ribose 5P => PRPP [PATH:dra00230]
Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:dra00230]
Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:dra00230]
Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:dra00230]
Other DBs
BSID: 
GO: 
Organism
Deinococcus radiodurans [GN:dra]
Gene
MutT/nudix family protein; K01515 ADP-ribose pyrophosphatase [EC:3.6.1.13] [KO:K01515] [EC:3.6.1.13]
MutT/nudix family protein; K01515 ADP-ribose pyrophosphatase [EC:3.6.1.13] [KO:K01515] [EC:3.6.1.13]
phosphopentomutase; K01839 phosphopentomutase [EC:5.4.2.7] [KO:K01839] [EC:5.4.2.7]
pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
ribose-phosphate pyrophosphokinase; K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1] [KO:K00948] [EC:2.7.6.1]
amidophosphoribosyltransferase; K00764 amidophosphoribosyltransferase [EC:2.4.2.14] [KO:K00764] [EC:2.4.2.14]
phosphoribosylamine--glycine ligase; K01945 phosphoribosylamine--glycine ligase [EC:6.3.4.13] [KO:K01945] [EC:6.3.4.13]
phosphoribosylglycinamide formyltransferase; K11175 phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] [KO:K11175] [EC:2.1.2.2]
phosphoribosylformylglycinamidine synthase II; K01952 phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] [KO:K01952] [EC:6.3.5.3]
phosphoribosylformylglycinamidine synthase I; K01952 phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] [KO:K01952] [EC:6.3.5.3]
hypothetical protein; K01952 phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] [KO:K01952] [EC:6.3.5.3]
phosphoribosylaminoimidazole synthetase; K01933 phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] [KO:K01933] [EC:6.3.3.1]
phosphoribosylaminoimidazole carboxylase; K01589 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18] [KO:K01589] [EC:6.3.4.18]
phosphoribosylaminoimidazole carboxylase; K01588 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] [KO:K01588] [EC:5.4.99.18]
phosphoribosylaminoimidazole-succinocarboxamide synthase; K01923 phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] [KO:K01923] [EC:6.3.2.6]
adenylosuccinate lyase; K01756 adenylosuccinate lyase [EC:4.3.2.2] [KO:K01756] [EC:4.3.2.2]
purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:3.5.4.10 2.1.2.3]
adenine phosphoribosyltransferase; K00759 adenine phosphoribosyltransferase [EC:2.4.2.7] [KO:K00759] [EC:2.4.2.7]
5`-nucleotidase family protein; K01081 5'-nucleotidase [EC:3.1.3.5] [KO:K01081] [EC:3.1.3.5]
5'-nucleotidase; K01081 5'-nucleotidase [EC:3.1.3.5] [KO:K01081] [EC:3.1.3.5]
surE; stationary phase survival protein SurE [KO:K03787] [EC:3.1.3.5]
deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
inosine-uridine preferring nucleoside hydrolase; K01239 purine nucleosidase [EC:3.2.2.1] [KO:K01239] [EC:3.2.2.1]
hypoxanthine-guanine phosphoribosyltransferase; K00760 hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] [KO:K00760] [EC:2.4.2.8]
inosine-5`-monophosphate dehydrogenase; K00088 IMP dehydrogenase [EC:1.1.1.205] [KO:K00088] [EC:1.1.1.205]
ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
nucleoside triphosphate pyrophosphohydrolase; K02428 XTP/dITP diphosphohydrolase [EC:3.6.1.66] [KO:K02428] [EC:3.6.1.66]
putative deoxyribonucleotide triphosphate pyrophosphatase; K02428 XTP/dITP diphosphohydrolase [EC:3.6.1.66] [KO:K02428] [EC:3.6.1.66]
xanthine phosphoribosyltransferase; K03816 xanthine phosphoribosyltransferase [EC:2.4.2.22] [KO:K03816] [EC:2.4.2.22]
xanthine dehydrogenase; K13481 xanthine dehydrogenase small subunit [EC:1.17.1.4] [KO:K13481] [EC:1.17.1.4]
xanthine dehydrogenase; K13482 xanthine dehydrogenase large subunit [EC:1.17.1.4] [KO:K13482] [EC:1.17.1.4]
oxidoreductase; K11177 xanthine dehydrogenase YagR molybdenum-binding subunit [EC:1.17.1.4] [KO:K11177] [EC:1.17.1.4]
oxidoreductase; K11177 xanthine dehydrogenase YagR molybdenum-binding subunit [EC:1.17.1.4] [KO:K11177] [EC:1.17.1.4]
oxidoreductase; K11178 xanthine dehydrogenase YagS FAD-binding subunit [EC:1.17.1.4] [KO:K11178] [EC:1.17.1.4]
oxidoreductase; K11178 xanthine dehydrogenase YagS FAD-binding subunit [EC:1.17.1.4] [KO:K11178] [EC:1.17.1.4]
oxidoreductase iron-sulfur subunit; K13483 xanthine dehydrogenase YagT iron-sulfur-binding subunit [KO:K13483]
oxidoreductase iron-sulfur subunit; K13483 xanthine dehydrogenase YagT iron-sulfur-binding subunit [KO:K13483]
guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
guanine deaminase; K01487 guanine deaminase [EC:3.5.4.3] [KO:K01487] [EC:3.5.4.3]
gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
pyruvate kinase; K00873 pyruvate kinase [EC:2.7.1.40] [KO:K00873] [EC:2.7.1.40]
ribonucleoside-diphosphate reductase; K00525 ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] [KO:K00525] [EC:1.17.4.1]
ribonucleoside-diphosphate reductase-like protein; K00525 ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] [KO:K00525] [EC:1.17.4.1]
nrdF; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
deoxyguanosinetriphosphate triphosphohydrolase-like protein; K01129 dGTPase [EC:3.1.5.1] [KO:K01129] [EC:3.1.5.1]
dGTP triphosphohydrolase-like protein; K01129 dGTPase [EC:3.1.5.1] [KO:K01129] [EC:3.1.5.1]
DNA-directed RNA polymerase subunit alpha; K03040 DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] [KO:K03040] [EC:2.7.7.6]
rpoB; DNA-directed RNA polymerase subunit beta [KO:K03043] [EC:2.7.7.6]
DNA-directed RNA polymerase subunit beta'; K03046 DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] [KO:K03046] [EC:2.7.7.6]
rpoZ; DNA-directed RNA polymerase subunit omega [KO:K03060] [EC:2.7.7.6]
DNA-directed DNA polymerase; K02335 DNA polymerase I [EC:2.7.7.7] [KO:K02335] [EC:2.7.7.7]
DNA polymerase III subunit alpha; K02337 DNA polymerase III subunit alpha [EC:2.7.7.7] [KO:K02337] [EC:2.7.7.7]
DNA polymerase III subunit beta; K02338 DNA polymerase III subunit beta [EC:2.7.7.7] [KO:K02338] [EC:2.7.7.7]
DNA polymerase III; K02343 DNA polymerase III subunit gamma/tau [EC:2.7.7.7] [KO:K02343] [EC:2.7.7.7]
hypothetical protein; K02340 DNA polymerase III subunit delta [EC:2.7.7.7] [KO:K02340] [EC:2.7.7.7]
DNA polymerase III subunit epsilon; K02342 DNA polymerase III subunit epsilon [EC:2.7.7.7] [KO:K02342] [EC:2.7.7.7]
exopolyphosphatase; K01524 exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40] [KO:K01524] [EC:3.6.1.40 3.6.1.11]
GTP pyrophosphokinase; K00951 GTP pyrophosphokinase [EC:2.7.6.5] [KO:K00951] [EC:2.7.6.5]
adenylosuccinate synthetase; K01939 adenylosuccinate synthase [EC:6.3.4.4] [KO:K01939] [EC:6.3.4.4]
adenine deaminase; K01486 adenine deaminase [EC:3.5.4.2] [KO:K01486] [EC:3.5.4.2]
cpdB; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein [KO:K01119] [EC:3.1.4.16]
adenylate kinase; K00939 adenylate kinase [EC:2.7.4.3] [KO:K00939] [EC:2.7.4.3]
polynucleotide phosphorylase/polyadenylase; K00962 polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] [KO:K00962] [EC:2.7.7.8]
adenylylsulfate kinase; K00860 adenylylsulfate kinase [EC:2.7.1.25] [KO:K00860] [EC:2.7.1.25]
sat; sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
uricase; K00365 urate oxidase [EC:1.7.3.3] [KO:K00365] [EC:1.7.3.3]
hypothetical protein; K07127 5-hydroxyisourate hydrolase [EC:3.5.2.17] [KO:K07127] [EC:3.5.2.17]
hypothetical protein; K13485 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:4.1.1.97] [KO:K13485] [EC:4.1.1.97]
allantoinase; K01466 allantoinase [EC:3.5.2.5] [KO:K01466] [EC:3.5.2.5]
allantoate amidohydrolase; K02083 allantoate deiminase [EC:3.5.3.9] [KO:K02083] [EC:3.5.3.9]
hypothetical protein; K14977 (S)-ureidoglycine aminohydrolase [EC:3.5.3.26] [KO:K14977] [EC:3.5.3.26]
ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
bifunctional urease subunit gamma/beta; K14048 urease subunit gamma/beta [EC:3.5.1.5] [KO:K14048] [EC:3.5.1.5]
Compound
C00002  
ATP
C00008  
ADP
C00011  
CO2
C00014  
Ammonia
C00020  
AMP
C00035  
GDP
C00037  
Glycine
C00039  
DNA
C00044  
GTP
C00046  
RNA
C00048  
Glyoxylate
C00053  
3'-Phosphoadenylyl sulfate
C00054  
Adenosine 3',5'-bisphosphate
C00059  
Sulfate
C00064  
L-Glutamine
C00081  
ITP
C00086  
Urea
C00104  
IDP
C00117  
D-Ribose 5-phosphate
C00119  
5-Phospho-alpha-D-ribose 1-diphosphate
C00130  
IMP
C00131  
dATP
C00144  
GMP
C00147  
Adenine
C00169  
Carbamoyl phosphate
C00206  
dADP
C00212  
Adenosine
C00224  
Adenylyl sulfate
C00242  
Guanine
C00262  
Hypoxanthine
C00286  
dGTP
C00294  
Inosine
C00301  
ADP-ribose
C00330  
Deoxyguanosine
C00360  
dAMP
C00361  
dGDP
C00362  
dGMP
C00366  
Urate
C00385  
Xanthine
C00387  
Guanosine
C00499  
Allantoate
C00559  
Deoxyadenosine
C00575  
3',5'-Cyclic AMP
C00603  
(-)-Ureidoglycolate
C00620  
alpha-D-Ribose 1-phosphate
C00655  
Xanthosine 5'-phosphate
C00700  
XTP
C00802  
Oxalureate
C00942  
3',5'-Cyclic GMP
C01228  
Guanosine 3',5'-bis(diphosphate)
C01260  
P1,P4-Bis(5'-adenosyl) tetraphosphate
C01261  
P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  
dIDP
C01345  
dITP
C01367  
3'-AMP
C01762  
Xanthosine
C02091  
(S)-Ureidoglycine
C02348  
(R)(-)-Allantoin
C02350  
(S)-Allantoin
C02353  
2',3'-Cyclic AMP
C02718  
N-Formiminoglycine
C03090  
5-Phosphoribosylamine
C03373  
Aminoimidazole ribotide
C03483  
Adenosine tetraphosphate
C03614  
Inosine 5'-tetraphosphate
C03794  
N6-(1,2-Dicarboxyethyl)-AMP
C03838  
5'-Phosphoribosylglycinamide
C04051  
5-Amino-4-imidazolecarboxyamide
C04376  
5'-Phosphoribosyl-N-formylglycinamide
C04392  
P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  
Guanosine 3'-diphosphate 5'-triphosphate
C04640  
2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  
1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  
1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  
1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  
5-Aminoimidazole
C05512  
Deoxyinosine
C05513  
Urate-3-ribonucleoside
C05515  
5-Ureido-4-imidazole carboxylate
C05516  
5-Amino-4-imidazole carboxylate
C05993  
Acetyl adenylate
C06193  
Guanosine 3'-phosphate
C06194  
2',3'-Cyclic GMP
C06195  
Imidazolone
C06196  
2'-Deoxyinosine 5'-phosphate
C06197  
P1,P3-Bis(5'-adenosyl) triphosphate
C06433  
5'-Benzoylphosphoadenosine
C06435  
5'-Butyrylphosphoinosine
C11821  
5-Hydroxyisourate
C12248  
5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  
5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
Reference
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
Reference
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
KO pathway
 

DBGET integrated database retrieval system