KEGG   PATHWAY: dra00360Help
Entry
dra00360                    Pathway                                

Name
Phenylalanine metabolism - Deinococcus radiodurans
Class
Metabolism; Amino acid metabolism
BRITE hierarchy
Pathway map
Phenylalanine metabolism
dra00360

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BSID: 
GO: 
Organism
Deinococcus radiodurans [GN:dra]
Gene
flavin monoamine oxidase-like protein; K00274 monoamine oxidase [EC:1.4.3.4] [KO:K00274] [EC:1.4.3.4]
phenylacetyl-CoA ligase; K01912 phenylacetate-CoA ligase [EC:6.2.1.30] [KO:K01912] [EC:6.2.1.30]
phenylacetic acid degradation protein PaaI; K02614 acyl-CoA thioesterase [EC:3.1.2.-] [KO:K02614] [EC:3.1.2.-]
paaA; phenylacetate-CoA oxygenase subunit PaaA [KO:K02609] [EC:1.14.13.149]
phenylacetic acid degradation protein PaaB; K02610 ring-1,2-phenylacetyl-CoA epoxidase subunit PaaB [KO:K02610]
phenylacetic acid degradation protein PaaC; K02611 ring-1,2-phenylacetyl-CoA epoxidase subunit PaaC [EC:1.14.13.149] [KO:K02611] [EC:1.14.13.149]
phenylacetic acid degradation protein PaaD; K02612 ring-1,2-phenylacetyl-CoA epoxidase subunit PaaD [KO:K02612]
enoyl-CoA hydratase; K15866 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase [EC:5.3.3.18] [KO:K15866] [EC:5.3.3.18]
bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; K02618 oxepin-CoA hydrolase / 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase [EC:3.3.2.12 1.17.1.7] [KO:K02618] [EC:1.17.1.7 3.3.2.12]
enoyl-CoA hydratase; K01692 enoyl-CoA hydratase [EC:4.2.1.17] [KO:K01692] [EC:4.2.1.17]
3-hydroxybutyryl-CoA dehydrogenase; K00074 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] [KO:K00074] [EC:1.1.1.157]
3-hydroxybutyryl-CoA dehydrogenase; K00074 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] [KO:K00074] [EC:1.1.1.157]
aspartate aminotransferase; K00812 aspartate aminotransferase [EC:2.6.1.1] [KO:K00812] [EC:2.6.1.1]
histidinol-phosphate aminotransferase; K00817 histidinol-phosphate aminotransferase [EC:2.6.1.9] [KO:K00817] [EC:2.6.1.9]
histidinol-phosphate aminotransferase; K00817 histidinol-phosphate aminotransferase [EC:2.6.1.9] [KO:K00817] [EC:2.6.1.9]
amidase; K01426 amidase [EC:3.5.1.4] [KO:K01426] [EC:3.5.1.4]
amidase; K01426 amidase [EC:3.5.1.4] [KO:K01426] [EC:3.5.1.4]
6-aminohexanoate-cyclic-dimer hydrolase; K01426 amidase [EC:3.5.1.4] [KO:K01426] [EC:3.5.1.4]
ferredoxin; K05710 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin subunit [KO:K05710]
Compound
C00022  
Pyruvate
C00024  
Acetyl-CoA
C00042  
Succinate
C00079  
L-Phenylalanine
C00082  
L-Tyrosine
C00083  
Malonyl-CoA
C00084  
Acetaldehyde
C00091  
Succinyl-CoA
C00122  
Fumarate
C00156  
4-Hydroxybenzoate
C00166  
Phenylpyruvate
C00180  
Benzoate
C00223  
p-Coumaroyl-CoA
C00323  
Caffeoyl-CoA
C00406  
Feruloyl-CoA
C00423  
trans-Cinnamate
C00512  
S-Benzoate coenzyme A
C00582  
Phenylacetyl-CoA
C00596  
2-Hydroxy-2,4-pentadienoate
C00601  
Phenylacetaldehyde
C00630  
2-Methylpropanoyl-CoA
C00642  
4-Hydroxyphenylacetate
C00755  
4-Hydroxy-3-methoxy-benzaldehyde
C00805  
Salicylate
C00811  
4-Coumarate
C01198  
3-(2-Hydroxyphenyl)propanoate
C01575  
Ephedrine
C01586  
Hippurate
C01772  
trans-2-Hydroxycinnamate
C02137  
alpha-Oxo-benzeneacetic acid
C02232  
3-Oxoadipyl-CoA
C02265  
D-Phenylalanine
C02505  
2-Phenylacetamide
C02763  
2-Hydroxy-3-phenylpropenoate
C02765  
(+)-Pseudoephedrine
C03519  
N-Acetyl-L-phenylalanine
C03589  
4-Hydroxy-2-oxopentanoate
C04044  
3-(2,3-Dihydroxyphenyl)propanoate
C04148  
Phenylacetylglutamine
C04351  
(R)-2-Methylimino-1-phenylpropan-1-ol
C04479  
2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate
C05332  
Phenethylamine
C05593  
3-Hydroxyphenylacetate
C05598  
Phenylacetylglycine
C05607  
Phenyllactate
C05620  
N-Acetyl-D-phenylalanine
C05629  
Phenylpropanoate
C05852  
2-Hydroxyphenylacetate
C05853  
Phenylethyl alcohol
C06207  
2,6-Dihydroxyphenylacetate
C06866  
Capsaicin
C07086  
Phenylacetic acid
C07303  
4-Hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA
C08300  
D-Cathine
C08301  
D-Cathinone
C11457  
3-(3-Hydroxyphenyl)propanoic acid
C11588  
cis-3-(Carboxy-ethyl)-3,5-cyclo-hexadiene-1,2-diol
C12621  
trans-3-Hydroxycinnamate
C12622  
cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol
C12623  
trans-2,3-Dihydroxycinnamate
C12624  
2-Hydroxy-6-ketononatrienedioate
C14144  
5-Carboxy-2-pentenoyl-CoA
C14145  
(3S)-3-Hydroxyadipyl-CoA
C15524  
Phenylglyoxylyl-CoA
C16666  
Vanillylamine
C16719  
(-)-Norephedrine
C17268  
Pyruvophenone
C18202  
8-Methyl-6-nonenoic acid
C19945  
3-Oxo-5,6-dehydrosuberyl-CoA
C19946  
3-Oxo-5,6-dehydrosuberyl-CoA semialdehyde
C19975  
2-Oxepin-2(3H)-ylideneacetyl-CoA
C20062  
2-(1,2-Epoxy-1,2-dihydrophenyl)acetyl-CoA
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
  Authors
Arai H, Yamamoto T, Ohishi T, Shimizu T, Nakata T, Kudo T.
  Title
Genetic organization and characteristics of the 3-(3-hydroxyphenyl)propionic acid degradation pathway of Comamonas testosteroni TA441.
  Journal
Microbiology 145 ( Pt 10):2813-20 (1999)
Reference
PMID:9603882
  Authors
Diaz E, Ferrandez A, Garcia JL.
  Title
Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12.
  Journal
J Bacteriol 180:2915-23 (1998)
Reference
PMID:9098055
  Authors
Ferrandez A, Garcia JL, Diaz E.
  Title
Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia coli K-12.
  Journal
J Bacteriol 179:2573-81 (1997)
Reference
  Authors
Hwang JY, Park J, Seo JH, Cha M, Cho BK, Kim J, Kim BG
  Title
Simultaneous synthesis of 2-phenylethanol and L-homophenylalanine using aromatic transaminase with yeast Ehrlich pathway.
  Journal
Biotechnol Bioeng 102:1323-9 (2009)
Reference
  Authors
Teufel R, Mascaraque V, Ismail W, Voss M, Perera J, Eisenreich W, Haehnel W, Fuchs G
  Title
Bacterial phenylalanine and phenylacetate catabolic pathway revealed.
  Journal
Proc Natl Acad Sci U S A 107:14390-5 (2010)
KO pathway
 

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