KEGG   PATHWAY: dra00760Help
Entry
dra00760                    Pathway                                

Name
Nicotinate and nicotinamide metabolism - Deinococcus radiodurans
Class
Metabolism; Metabolism of cofactors and vitamins
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Nicotinate and nicotinamide metabolism
dra00760

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BSID: 
UMBBD: 
GO: 
Organism
Deinococcus radiodurans [GN:dra]
Gene
nicotinate phosphoribosyltransferase; K00763 nicotinate phosphoribosyltransferase [EC:6.3.4.21] [KO:K00763] [EC:6.3.4.21]
deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
5`-nucleotidase family protein; K01081 5'-nucleotidase [EC:3.1.3.5] [KO:K01081] [EC:3.1.3.5]
5'-nucleotidase; K01081 5'-nucleotidase [EC:3.1.3.5] [KO:K01081] [EC:3.1.3.5]
surE; stationary phase survival protein SurE [KO:K03787] [EC:3.1.3.5]
bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase; K13522 bifunctional NMN adenylyltransferase/nudix hydrolase [EC:2.7.7.1 3.6.1.-] [KO:K13522] [EC:3.6.1.- 2.7.7.1]
MutT/nudix family protein; K03426 NAD+ diphosphatase [EC:3.6.1.22] [KO:K03426] [EC:3.6.1.22]
nadE; NAD synthetase [KO:K01916] [EC:6.3.1.5]
inosine-uridine preferring nucleoside hydrolase; K01239 purine nucleosidase [EC:3.2.2.1] [KO:K01239] [EC:3.2.2.1]
putative nicotinate phosphoribosyltransferase; K03462 nicotinamide phosphoribosyltransferase [EC:2.4.2.12] [KO:K03462] [EC:2.4.2.12]
Compound
C00003  
NAD+
C00006  
NADP+
C00022  
Pyruvate
C00049  
L-Aspartate
C00111  
Glycerone phosphate
C00122  
Fumarate
C00153  
Nicotinamide
C00163  
Propanoate
C00232  
Succinate semialdehyde
C00253  
Nicotinate
C00455  
Nicotinamide D-ribonucleotide
C00857  
Deamino-NAD+
C00922  
2,3-Dimethylmaleate
C01004  
N-Methylnicotinate
C01020  
6-Hydroxynicotinate
C01056  
(S)-6-Hydroxynicotine
C01059  
2,5-Dihydroxypyridine
C01185  
Nicotinate D-ribonucleotide
C01297  
6-Hydroxypseudooxynicotine
C01384  
Maleic acid
C01596  
Maleamate
C02295  
Methylitaconate
C02918  
1-Methylnicotinamide
C02930  
2-Methyleneglutarate
C03043  
(R)-6-Hydroxynicotine
C03056  
2,6-Dihydroxypyridine
C03150  
Nicotinamide-beta-riboside
C03458  
2,3,6-Trihydroxypyridine
C03652  
(2R,3S)-2,3-Dimethylmalate
C03722  
Quinolinate
C04226  
6-Oxo-1,4,5,6-tetrahydronicotinate
C05380  
Nicotinurate
C05840  
Iminoaspartate
C05841  
Nicotinate D-ribonucleoside
C05842  
N1-Methyl-2-pyridone-5-carboxamide
C05843  
N1-Methyl-4-pyridone-5-carboxamide
C06178  
1-Methylpyrrolinium
C15523  
2,6-Dihydroxynicotinate
C15986  
2,6-Dihydroxypseudooxynicotine
C15987  
4-Methylaminobutyrate
C16150  
(R,S)-Nicotine
C16151  
2,6-Dihydroxy-N-methylmyosmine
C16152  
Blue pigment
C16159  
2-Formylglutarate
C16390  
(S)-2-(Hydroxymethyl)glutarate
C18232  
N-Formylmaleamic acid
C19631  
6-Hydroxy-3-succinoylpyridine
Reference
  Authors
BEHRMAN EJ, STANIER RY.
  Title
The bacterial oxidation of nicotinic acid.
  Journal
J Biol Chem 228:923-45 (1957)
Reference
  Authors
Alhapel A, Darley DJ, Wagener N, Eckel E, Elsner N, Pierik AJ.
  Title
Molecular and functional analysis of nicotinate catabolism in Eubacterium barkeri.
  Journal
Proc Natl Acad Sci U S A 103:12341-6 (2006)
Reference
  Authors
Baitsch D, Sandu C, Brandsch R, Igloi GL.
  Title
Gene cluster on pAO1 of Arthrobacter nicotinovorans involved in degradation of the plant alkaloid nicotine: cloning, purification, and characterization of 2,6-dihydroxypyridine 3-hydroxylase.
  Journal
J Bacteriol 183:5262-7 (2001)
Reference
  Authors
Sachelaru P, Schiltz E, Igloi GL, Brandsch R.
  Title
An alpha/beta-fold C--C bond hydrolase is involved in a central step of nicotine catabolism by Arthrobacter nicotinovorans.
  Journal
J Bacteriol 187:8516-9 (2005)
Reference
PMID:5835946
  Authors
Gherna RL, Richardson SH, Rittenberg SC
  Title
The bacterial oxidation of nicotine. VI. The metabolism of 2,6-dihydroxypseudooxynicotine.
  Journal
J Biol Chem 240:3669-74 (1965)
Reference
  Authors
Galeazzi L, Bocci P, Amici A, Brunetti L, Ruggieri S, Romine M, Reed S, Osterman AL, Rodionov DA, Sorci L, Raffaelli N
  Title
Identification of nicotinamide mononucleotide deamidase of the bacterial pyridine nucleotide cycle reveals a novel broadly conserved amidohydrolase family.
  Journal
J Biol Chem 286:40365-75 (2011)
KO pathway
 

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