KEGG   PATHWAY: dre00190Help
Entry
dre00190                    Pathway                                

Name
Oxidative phosphorylation - Danio rerio (zebrafish)
Class
Metabolism; Energy metabolism
BRITE hierarchy
Pathway map
Oxidative phosphorylation
dre00190

All organismsOrtholog table
Module
NADH:ubiquinone oxidoreductase, mitochondria [PATH:dre00190]
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:dre00190]
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex [PATH:dre00190]
NADH dehydrogenase (ubiquinone) 1 beta subcomplex [PATH:dre00190]
Succinate dehydrogenase (ubiquinone) [PATH:dre00190]
Cytochrome bc1 complex respiratory unit [PATH:dre00190]
Cytochrome bc1 complex [PATH:dre00190]
Cytochrome c oxidase [PATH:dre00190]
F-type ATPase, eukaryotes [PATH:dre00190]
V-type ATPase, eukaryotes [PATH:dre00190]
Organism
Danio rerio (zebrafish) [GN:dre]
Gene
140531  
ND1; NADH dehydrogenase subunit 1 [KO:K03878] [EC:1.6.5.3]
140532  
ND2; NADH dehydrogenase subunit 2 [KO:K03879] [EC:1.6.5.3]
140533  
ND3; NADH dehydrogenase subunit 3 [KO:K03880] [EC:1.6.5.3]
140534  
ND4; NADH dehydrogenase subunit 4 [KO:K03881] [EC:1.6.5.3]
140538  
ND4L; NADH dehydrogenase subunit 4L [KO:K03882] [EC:1.6.5.3]
140535  
ND5; NADH dehydrogenase subunit 5 [KO:K03883] [EC:1.6.5.3]
140536  
ND6; NADH dehydrogenase subunit 6 [KO:K03884] [EC:1.6.5.3]
493605  
ndufs1; NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial [KO:K03934] [EC:1.6.99.3 1.6.5.3]
641476  
zgc:123301; uncharacterized protein LOC641476 [KO:K03935] [EC:1.6.99.3 1.6.5.3]
553672  
ndufs2; NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial [KO:K03935] [EC:1.6.99.3 1.6.5.3]
550451  
ndufs3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial [KO:K03936] [EC:1.6.99.3 1.6.5.3]
573689  
ndufs4; NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial [KO:K03937]
553660  
ndufs5; NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 [KO:K03938]
447913  
ndufs6; NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial [KO:K03939]
796997  
ndufs7; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial [KO:K03940] [EC:1.6.99.3 1.6.5.3]
406413  
ndufs8a; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial [KO:K03941] [EC:1.6.99.3 1.6.5.3]
554100  
ndufs8b; NADH dehydrogenase (ubiquinone) Fe-S protein 8b [KO:K03941] [EC:1.6.99.3 1.6.5.3]
445291  
ndufv1; NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial [KO:K03942] [EC:1.6.99.3 1.6.5.3]
641566  
zgc:123290; uncharacterized protein LOC641566 [KO:K03942] [EC:1.6.99.3 1.6.5.3]
393720  
ndufv2; NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial [KO:K03943] [EC:1.6.99.3 1.6.5.3]
415243  
ndufa1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 [KO:K03945]
554125  
ndufa2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 [KO:K03946]
445122  
ndufa3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 [KO:K03947]
406726  
ndufa4l; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 4, like [KO:K03948]
406298  
ndufa4; cytochrome c oxidase subunit NDUFA4 [KO:K03948]
ndufa4l2a; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 [KO:K03948]
541328  
ndufa5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 [KO:K03949]
393943  
ndufa6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 [KO:K03950]
445042  
ndufa7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 [KO:K03951]
393700  
ndufa8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 [KO:K03952]
541331  
ndufa9a; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial [KO:K03953]
321951  
ndufa10; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial [KO:K03954]
325712  
ndufab1b; acyl carrier protein, mitochondrial [KO:K03955]
573619  
ndufab1a; NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex 1-like [KO:K03955]
393497  
ndufa11; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 [KO:K03956]
556538  
ndufa12; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 [KO:K11352]
393687  
ndufa13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 [KO:K11353]
393764  
ndufb2; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial [KO:K03958]
ndufb3; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 [KO:K03959]
406306  
ndufb4; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 [KO:K03960]
797063  
ndufb5; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial [KO:K03961]
393781  
ndufb6; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 [KO:K03962]
393821  
ndufb7; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 [KO:K03963]
393829  
ndufb8; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial [KO:K03964]
573021  
ndufb9; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 [KO:K03965]
393703  
ndufb10; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 [KO:K03966]
562219  
ndufb11; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial [KO:K11351]
si:ch211-235e9.6; NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial [KO:K03967]
541390  
ndufc2; NADH dehydrogenase [ubiquinone] 1 subunit C2 [KO:K03968]
393884  
sdha; succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial precursor [KO:K00234] [EC:1.3.5.1]
562149  
sdhb; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial precursor [KO:K00235] [EC:1.3.5.1]
445129  
sdhc; succinate dehydrogenase cytochrome b560 subunit, mitochondrial [KO:K00236]
436762  
sdhda; succinate dehydrogenase [ubiquinone] cytochrome b small subunit A, mitochondrial [KO:K00237]
445500  
sdhdb; succinate dehydrogenase [ubiquinone] cytochrome b small subunit B, mitochondrial [KO:K00237]
406359  
uqcrfs1; cytochrome b-c1 complex subunit Rieske, mitochondrial [KO:K00411] [EC:1.10.2.2]
140512  
CYTB; cytochrome b [KO:K00412]
564379  
cyc1; cytochrome c-1 [KO:K00413]
393793  
uqcrc1; cytochrome b-c1 complex subunit 1, mitochondrial [KO:K00414]
436930  
uqcrc2a; ubiquinol-cytochrome c reductase core protein II [KO:K00415]
322549  
uqcrc2b; cytochrome b-c1 complex subunit 2, mitochondrial [KO:K00415]
566723  
uqcrh; cytochrome b-c1 complex subunit 6, mitochondrial [KO:K00416]
554154  
uqcrb; cytochrome b-c1 complex subunit 7 [KO:K00417]
436768  
uqcrq; cytochrome b-c1 complex subunit 8 [KO:K00418]
uqcr10; cytochrome b-c1 complex subunit 9 [KO:K00419]
si:ch1073-325m22.2; cytochrome b-c1 complex subunit 10 [KO:K00420]
553384  
cox10; protoheme IX farnesyltransferase, mitochondrial [KO:K02257] [EC:2.5.1.-]
140541  
COX3; cytochrome c oxidase subunit III [KO:K02262]
140539  
COX1; cytochrome c oxidase subunit I [KO:K02256] [EC:1.9.3.1]
140540  
COX2; cytochrome c oxidase subunit II [KO:K02261]
326975  
cox4i1; cytochrome c oxidase subunit 4 isoform 1, mitochondrial [KO:K02263]
393776  
cox4i2; cytochrome c oxidase subunit IV isoform 2 [KO:K02263]
402880  
cox4i1l; cytochrome c oxidase subunit 4 isoform 1, mitochondrial [KO:K02263]
554101  
cox5aa; cytochrome c oxidase subunit Vaa [KO:K02264]
326962  
cox5ab; cytochrome c oxidase subunit Vab [KO:K02264]
cox5b1; cytochrome c oxidase subunit 5B, mitochondrial-like [KO:K02265]
415253  
zgc:86599; uncharacterized protein LOC415253 [KO:K02265]
751638  
cox5b2; cytochrome c oxidase subunit Vb 2 [KO:K02265]
447942  
cox6a2; cytochrome c oxidase subunit VIa-like [KO:K02266]
335774  
cox6a1; cytochrome c oxidase subunit 6A1, mitochondrial [KO:K02266]
393478  
cox6b2; cytochrome c oxidase subunit VIb polypeptide 2 [KO:K02267]
436968  
cox6b1; cytochrome c oxidase subunit VIb-like [KO:K02267]
494577  
cox6c; cytochrome c oxidase polypeptide VIc-like [KO:K02268]
335751  
cox7a3; cytochrome c oxidase subunit VIIa polypeptide 3 [KO:K02270]
554103  
cox7a2a; cytochrome c oxidase subunit VIIa polypeptide 2a (liver) [KO:K02270]
563476  
cox7b; cytochrome c oxidase subunit VIIb [KO:K02271]
336118  
cox7c; cytochrome c oxidase, subunit VIIc [KO:K02272]
569770  
cox8b; uncharacterized protein LOC569770 [KO:K02273]
557348  
cox8a; cytochrome c oxidase subunit VIIIA (ubiquitous) [KO:K02273]
cox11; COX11 homolog, cytochrome c oxidase assembly protein [KO:K02258]
394181  
cox15; COX15 homolog [KO:K02259]
447914  
cox17; COX17 homolog, cytochrome c oxidase assembly protein [KO:K02260]
553755  
atp5a1; ATP synthase subunit alpha, mitochondrial [KO:K02132]
554135  
atp5b; ATP synthase subunit beta, mitochondrial [KO:K02133] [EC:3.6.3.14]
zgc:163069; mitochondrial ATP synthase beta subunit [KO:K02133] [EC:3.6.3.14]
336957  
atp5c1; ATP synthase subunit gamma, mitochondrial isoform b [KO:K02136]
335709  
atp5d; ATP synthase subunit delta, mitochondrial [KO:K02134]
798291  
atp5e; ATP synthase subunit epsilon, mitochondrial [KO:K02135]
335191  
atp5o; ATP synthase subunit O, mitochondrial [KO:K02137]
140519  
ATP6; ATP synthase F0 subunit 6 [KO:K02126]
449787  
atp5f1; ATP synthase F(0) complex subunit B1, mitochondrial [KO:K02127]
81541  
atp5g3b; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c3 (subunit 9) b [KO:K02128]
394151  
atp5g3a; ATP synthase F(0) complex subunit C3, mitochondrial [KO:K02128]
406301  
atp5g1; ATP synthase F(0) complex subunit C1, mitochondrial [KO:K02128]
393675  
atp5h; ATP synthase subunit d, mitochondrial [KO:K02138]
767750  
atp5ib; ATP synthase subunit e, mitochondrial [KO:K02129]
559659  
atp5ia; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E-like [KO:K02129]
402883  
atp5j2; ATP synthase subunit f, mitochondrial [KO:K02130]
326977  
atp5l; ATP synthase subunit g, mitochondrial [KO:K02140]
406599  
atp5j; ATP synthase-coupling factor 6, mitochondrial [KO:K02131]
140520  
ATP8; ATP synthase F0 subunit 8 [KO:K02125]
394110  
atp6v1aa; V-type proton ATPase catalytic subunit A [KO:K02145] [EC:3.6.3.14]
337583  
atp6v1ab; V-type proton ATPase catalytic subunit A [KO:K02145] [EC:3.6.3.14]
359840  
atp6v1b2; V-type proton ATPase subunit B, brain isoform [KO:K02147]
359839  
atp6v1ba; V-type proton ATPase subunit B, kidney isoform [KO:K02147]
368907  
atp6v1c1a; V-type proton ATPase subunit C 1-A [KO:K02148]
449655  
atp6v1c1b; V-type proton ATPase subunit C 1-B [KO:K02148]
393935  
atp6v1d; V-type proton ATPase subunit D [KO:K02149]
192335  
atp6v1e1b; V-type proton ATPase subunit E 1 [KO:K02150]
436799  
atp6v1f; V-type proton ATPase subunit F [KO:K02151]
335025  
atp6v1g1; V-type proton ATPase subunit G 1 [KO:K02152]
286779  
atp6v1h; V-type proton ATPase subunit H isoform 1 [KO:K02144]
324307  
atp6v0a1a; V-type proton ATPase 116 kDa subunit a [KO:K02154]
553691  
atp6v0a1b; ATPase, H+ transporting, lysosomal V0 subunit a1b [KO:K02154]
406342  
tcirg1b; T-cell immune regulator 1 [KO:K02154]
tcirg1a; V-type proton ATPase 116 kDa subunit a [KO:K02154]
561469  
atp6v0a2a; V-type proton ATPase 116 kDa subunit a isoform X1 [KO:K02154]
561117  
atp6v0a2b; V-type proton ATPase 116 kDa subunit a isoform 2 [KO:K02154]
192336  
atp6v0ca; ATPase, H+ transporting, lysosomal, V0 subunit c, a [KO:K02155]
325402  
atp6v0cb; V-type proton ATPase 16 kDa proteolipid subunit [KO:K02155]
321724  
atp6v0b; V-type proton ATPase 21 kDa proteolipid subunit [KO:K03661]
322811  
atp6v0d1; V-type proton ATPase subunit d 1 [KO:K02146]
553767  
atpv0e2; ATPase, H+ transporting, V0 subunit [KO:K02153]
450017  
atp6v0e1; V-type proton ATPase subunit e 1 [KO:K02153]
195824  
atp6ap1b; ATPase, H+ transporting, lysosomal accessory protein 1b [KO:K03662]
atp6ap1a; V-type proton ATPase subunit S1 [KO:K03662]
550531  
ppa1b; inorganic pyrophosphatase [KO:K01507] [EC:3.6.1.1]
402961  
ppa2; inorganic pyrophosphatase 2, mitochondrial [KO:K01507] [EC:3.6.1.1]
393706  
ppa1a; inorganic pyrophosphatase 2, mitochondrial [KO:K01507] [EC:3.6.1.1]
lhpp; phospholysine phosphohistidine inorganic pyrophosphate phosphatase [KO:K11725] [EC:3.1.3.- 3.6.1.1]
Compound
C00001  
H2O
C00002  
ATP
C00003  
NAD+
C00004  
NADH
C00007  
Oxygen
C00008  
ADP
C00009  
Orthophosphate
C00013  
Diphosphate
C00042  
Succinate
C00061  
FMN
C00080  
H+
C00122  
Fumarate
C00390  
Ubiquinol
C00399  
Ubiquinone
C00524  
Cytochrome c
C00536  
Triphosphate
Reference
  Authors
Sazanov LA, Hinchliffe P.
  Title
Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus.
  Journal
Science 311:1430-6 (2006)
DOI:10.1126/science.1123809
Reference
  Authors
Hinchliffe P, Carroll J, Sazanov LA.
  Title
Identification of a novel subunit of respiratory complex I from Thermus thermophilus.
  Journal
Biochemistry 45:4413-20 (2006)
DOI:10.1021/bi0600998
KO pathway
 

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