KEGG   PATHWAY: dre04140Help
Entry
dre04140                    Pathway                                

Name
Autophagy - Danio rerio (zebrafish)
Class
Cellular Processes; Transport and catabolism
BRITE hierarchy
Pathway map
Autophagy
dre04140

All organismsOrtholog table
Other DBs
BSID: 
GO: 
Organism
Danio rerio (zebrafish) [GN:dre]
Gene
30262  
ins; preproinsulin [KO:K04526]
566735  
insb; preproinsulin b [KO:K04526]
572074  
prkaa2; protein kinase, AMP-activated, alpha 2 catalytic subunit [KO:K07198] [EC:2.7.11.11]
prkaa1; protein kinase, AMP-activated, alpha 1 catalytic subunit [KO:K07198] [EC:2.7.11.11]
ifnphi3; interferon phi 3 [KO:K05414]
360134  
ifnphi1; interferon phi 1 [KO:K05414]
405790  
ifng1-2; interferon, gamma 1-2 [KO:K04687]
558848  
ulk1b; unc-51 like autophagy activating kinase 1 [KO:K08269] [EC:2.7.11.1]
ulk3; unc-51 like kinase 3 [KO:K08269] [EC:2.7.11.1]
ulk2; unc-51 like autophagy activating kinase 2 [KO:K08269] [EC:2.7.11.1]
393405  
atg13; ATG13 autophagy related 13 homolog (S. cerevisiae) [KO:K08331]
564088  
pik3r4; phosphoinositide-3-kinase, regulatory subunit 4 [KO:K08333] [EC:2.7.11.1]
393846  
becn1; beclin 1, autophagy related [KO:K08334]
407686  
zgc:113944 [KO:K17889]
548346  
pik3c3; phosphatidylinositol 3-kinase, catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
570965  
atg12; ATG12 autophagy related 12 homolog (S. cerevisiae) [KO:K08336]
atg7; ATG7 autophagy related 7 homolog (S. cerevisiae) [KO:K08337]
641330  
atg10; ATG10 autophagy related 10 homolog (S. cerevisiae) [KO:K17888]
494180  
atg5; ATG5 autophagy related 5 homolog (S. cerevisiae) [KO:K08339]
550552  
atg16l1; ATG16 autophagy related 16-like 1 (S. cerevisiae) [KO:K17890]
atg16l2; ATG16 autophagy related 16-like 2 (S. cerevisiae) [KO:K20868]
403036  
gabarapl2; GABA(A) receptor-associated protein like 2 [KO:K08341]
793200  
gabarapb; GABA(A) receptor-associated protein b [KO:K08341]
326974  
gabarapa; GABA(A) receptor-associated protein a [KO:K08341]
554140  
atg4a; autophagy related 4A, cysteine peptidase [KO:K08342] [EC:3.4.22.-]
415193  
atg4c; autophagy related 4C, cysteine peptidase [KO:K08342] [EC:3.4.22.-]
448859  
atg4b; autophagy related 4B, cysteine peptidase [KO:K08342] [EC:3.4.22.-]
795933  
atg4da; autophagy related 4D, cysteine peptidase a [KO:K08342] [EC:3.4.22.-]
336632  
atg3; autophagy related 3 [KO:K08343]
Compound
C00350  
Phosphatidylethanolamine
C00913  
3-Methyladenine
C01194  
1-Phosphatidyl-D-myo-inositol
C04549  
1-Phosphatidyl-1D-myo-inositol 3-phosphate
C15181  
Wortmannin
Reference
  Authors
Meijer AJ, Codogno P.
  Title
Regulation and role of autophagy in mammalian cells.
  Journal
Int J Biochem Cell Biol 36:2445-62 (2004)
Reference
  Authors
Deretic V.
  Title
Autophagy in innate and adaptive immunity.
  Journal
Trends Immunol 26:523-8 (2005)
Reference
  Authors
Levine B, Yuan J.
  Title
Autophagy in cell death: an innocent convict?
  Journal
J Clin Invest 115:2679-88 (2005)
Reference
  Authors
Tanida I, Ueno T, Kominami E.
  Title
LC3 conjugation system in mammalian autophagy.
  Journal
Int J Biochem Cell Biol 36:2503-18 (2004)
Reference
  Authors
Lum JJ, DeBerardinis RJ, Thompson CB.
  Title
Autophagy in metazoans: cell survival in the land of plenty.
  Journal
Nat Rev Mol Cell Biol 6:439-48 (2005)
Reference
  Authors
Reggiori F, Klionsky DJ.
  Title
Autophagosomes: biogenesis from scratch?
  Journal
Curr Opin Cell Biol 17:415-22 (2005)
Reference
  Authors
Klionsky DJ, Emr SD.
  Title
Autophagy as a regulated pathway of cellular degradation.
  Journal
Science 290:1717-21 (2000)
Reference
  Authors
Bechet D, Tassa A, Taillandier D, Combaret L, Attaix D.
  Title
Lysosomal proteolysis in skeletal muscle.
  Journal
Int J Biochem Cell Biol 37:2098-114 (2005)
Reference
  Authors
He C, Klionsky DJ
  Title
Regulation mechanisms and signaling pathways of autophagy.
  Journal
Annu Rev Genet 43:67-93 (2009)
Reference
  Authors
Yang Z, Klionsky DJ
  Title
An overview of the molecular mechanism of autophagy.
  Journal
Curr Top Microbiol Immunol 335:1-32 (2009)
Reference
  Authors
Yang Z, Klionsky DJ
  Title
Mammalian autophagy: core molecular machinery and signaling regulation.
  Journal
Curr Opin Cell Biol 22:124-31 (2010)
Reference
  Authors
Chen Y, Klionsky DJ
  Title
The regulation of autophagy - unanswered questions.
  Journal
J Cell Sci 124:161-70 (2011)
Reference
  Authors
Mizushima N, Yoshimori T, Ohsumi Y
  Title
The role of Atg proteins in autophagosome formation.
  Journal
Annu Rev Cell Dev Biol 27:107-32 (2011)
Reference
  Authors
Russell RC, Yuan HX, Guan KL
  Title
Autophagy regulation by nutrient signaling.
  Journal
Cell Res 24:42-57 (2014)
Reference
  Authors
Noda NN, Fujioka Y
  Title
Atg1 family kinases in autophagy initiation.
  Journal
Cell Mol Life Sci 72:3083-96 (2015)
KO pathway
 

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