KEGG PATHWAY: dre05168

PATHWAY: dre05168

Entry

dre05168 Pathway

Name

Herpes simplex infection - Danio rerio (zebrafish)

Description

Herpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishment of latent infection in neuronal ganglia. HSV is the main cause of herpes infections that lead to the formation of characteristic blistering lesion. HSV express multiple viral accessory proteins that interfere with host immune responses and are indispensable for viral replication. Among these proteins, the immediate early (IE) gene ICP0, ICP4, and ICP27 are essential for regulation of HSV gene expression in productive infection. On the other hand, ORF P and ORF O gene are transcribed during latency and blocks the expression of the IE genes, thus maintaining latent infection.

Class

Human Diseases; Infectious diseases

Pathway map

dre05168

Herpes simplex infection

Module

dre_M00381

SCF-SKP2 complex [PATH:dre05168]

Organism

Danio rerio (zebrafish) [GN:dre]

Gene

554167	tnfb; tumor necrosis factor b (TNF superfamily, member 2) [KO:K05468]
798119	tumor necrosis factor ligand superfamily member 14-like; K05477 tumor necrosis factor ligand superfamily member 14 [KO:K05477]
798191	uncharacterized LOC798191; K05152 tumor necrosis factor receptor superfamily member 14 [KO:K05152]
791704	uncharacterized LOC791704; K05152 tumor necrosis factor receptor superfamily member 14 [KO:K05152]
100536255	tumor necrosis factor receptor superfamily member 14-like; K05152 tumor necrosis factor receptor superfamily member 14 [KO:K05152]
100148503	traf1; TNF receptor-associated factor 1 [KO:K03172]
557526	traf2b; Tnf receptor-associated factor 2b [KO:K03173]
564295	traf2a; Tnf receptor-associated factor 2a [KO:K03173]
100005446	TNF receptor-associated factor 2-like; K03173 TNF receptor-associated factor 2 [KO:K03173]
445119	traf3; TNF receptor-associated factor 3 [KO:K03174]
563887	traf5; Tnf receptor-associated factor 5 [KO:K09849]
569698	mapk10; mitogen-activated protein kinase 10 [KO:K04440] [EC:2.7.11.24]
562720	mapk8a; mitogen-activated protein kinase 8a [KO:K04440] [EC:2.7.11.24]
65236	mapk8b; mitogen-activated protein kinase 8b [KO:K04440] [EC:2.7.11.24]
100149273	mapk9; mitogen-activated protein kinase 9 [KO:K04440] [EC:2.7.11.24]
335916	jun; jun proto-oncogene [KO:K04448]
394198	fos; v-fos FBJ murine osteosarcoma viral oncogene homolog [KO:K04379]
564403	si:ch211-153j24.3; K04379 proto-oncogene protein c-fos [KO:K04379]
570238	proto-oncogene c-Fos-like; K04379 proto-oncogene protein c-fos [KO:K04379]
563560	ikbkb; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta [KO:K07209] [EC:2.7.11.10]
393287	chuk; conserved helix-loop-helix ubiquitous kinase [KO:K04467] [EC:2.7.11.10]
541530	ikbkg; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma [KO:K07210]
323099	nfkbiab; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b [KO:K04734]
406463	nfkbiaa; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a [KO:K04734]
415099	rela; v-rel reticuloendotheliosis viral oncogene homolog A [KO:K04735]
557665	pvrl1b; poliovirus receptor-related 1b [KO:K06081]
560816	poliovirus receptor-related protein 2-like; K06531 poliovirus receptor-related protein 2 [KO:K06531]
333979	ptpn11a; protein tyrosine phosphatase, non-receptor type 11, a [KO:K07293] [EC:3.1.3.48]
403125	tlr2; toll-like receptor 2 [KO:K10159]
403145	myd88; myeloid differentiation primary response gene (88) [KO:K04729]
554561	traf6; TNF receptor-associated factor 6 [KO:K03175]
403084	tab1; TGF-beta activated kinase 1/MAP3K7 binding protein 1 [KO:K04403]
553788	map3k7; mitogen activated protein kinase kinase kinase 7 [KO:K04427] [EC:2.7.11.25]
403128	tlr9; toll-like receptor 9 [KO:K10161]
403126	tlr3; toll-like receptor 3 [KO:K05401]
403147	ticam1; toll-like receptor adaptor molecule 1 [KO:K05842]
100537952	uncharacterized LOC100537952; K05842 toll-like receptor adapter molecule 1 [KO:K05842]
564854	irf3; interferon regulatory factor 3 [KO:K05411]
393650	irf7; interferon regulatory factor 7 [KO:K09447]
565759	novel protein similar to vertebrate interferon induced with helicase C domain 1 (IFIH1); K12647 interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13] [KO:K12647] [EC:3.6.4.13]
562867	mavs; mitochondrial antiviral signaling protein [KO:K12648]
437024	ikbke; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon [KO:K07211] [EC:2.7.11.10]
692289	tbk1; TANK-binding kinase 1 [KO:K05410] [EC:2.7.11.10]
405785	tnfa; tumor necrosis factor a (TNF superfamily, member 2) [KO:K03156]
405770	il1b; interleukin 1, beta [KO:K04519]
100885851	il6; interleukin 6 (interferon, beta 2) [KO:K05405]
100004358	interleukin-12 subunit alpha-like; K05406 interleukin 12A [KO:K05406]
445373	il12ba; interleukin 12Ba [KO:K05425]
654826	il15; interleukin 15 [KO:K05433]
100126803	ifnphi3; interferon phi 3 [KO:K05414]
360134	ifnphi1; interferon phi 1 [KO:K05414]
553758	usp7; ubiquitin specific peptidase 7 (herpes virus-associated) [KO:K11838] [EC:3.1.2.15]
565338	eif2ak1; eukaryotic translation initiation factor 2-alpha kinase 1 [KO:K16194] [EC:2.7.11.1]
100001092	eif2ak2; eukaryotic translation initiation factor 2-alpha kinase 2 [KO:K16195] [EC:2.7.11.1]
503703	pkz; protein kinase containing Z-DNA binding domains [KO:K08860] [EC:2.7.11.1]
100149925	eif2ak4; eukaryotic translation initiation factor 2 alpha kinase 4 [KO:K16196] [EC:2.7.11.1]
321564	eif2s1b; eukaryotic translation initiation factor 2, subunit 1 alpha b [KO:K03237]
327301	ppp1cab; protein phosphatase 1, catalytic subunit, alpha isoform b [KO:K06269] [EC:3.1.3.16]
407980	ppp1caa; protein phosphatase 1, catalytic subunit, alpha isoform a [KO:K06269] [EC:3.1.3.16]
334597	ppp1cbl; protein phosphatase 1, catalytic subunit, beta isoform, like [KO:K06269] [EC:3.1.3.16]
100003223	ppp1cb; protein phosphatase 1, catalytic subunit, beta isoform [KO:K06269] [EC:3.1.3.16]
571753	ppp1cc; protein phosphatase 1, catalytic subunit, gamma isoform [KO:K06269] [EC:3.1.3.16]
30491	c3b; complement component c3b [KO:K03990]
565074	c3c; complement component c3c [KO:K03990]
565774	c5; complement component 5 [KO:K03994]
100149189	complement factor properdin; K15412 complement factor properdin [KO:K15412]
393716	skp1; S-phase kinase-associated protein 1 [KO:K03094]
436873	ube2r2; ubiquitin-conjugating enzyme E2R 2 [KO:K02207] [EC:6.3.2.19]
393933	cdc34a; cell division cycle 34 homolog (S. cerevisiae) a [KO:K02207] [EC:6.3.2.19]
323883	cul1a; cullin 1a [KO:K03347]
406816	cul1b; cullin 1b [KO:K03347]
563708	skp2; S-phase kinase-associated protein 2 (p45) [KO:K03875]
565501	eef1da; elongation factor-1, delta, a [KO:K15410]
560745	eef1db; elongation factor-1, delta, b [KO:K15410]
322404	fb60b03; zgc:123178 [KO:K14840]
406557	mcrs1; microspherule protein 1 [KO:K11674]
553347	polr2a; polymerase (RNA) II (DNA directed) polypeptide A [KO:K03006] [EC:2.7.7.6]
323679	srpk1a; serine/arginine-rich protein specific kinase 1a [KO:K15409] [EC:2.7.11.1]
791187	srpk1b; serine/arginine-rich protein specific kinase 1b [KO:K15409] [EC:2.7.11.1]
406288	srsf1a; serine/arginine-rich splicing factor 1a [KO:K12890]
393565	srsf1b; serine/arginine-rich splicing factor 1b [KO:K12890]
405835	srsf9; serine/arginine-rich splicing factor 9 [KO:K12890]
406691	srsf2a; serine/arginine-rich splicing factor 2a [KO:K12891]
323700	srsf2b; serine/arginine-rich splicing factor 2b [KO:K12891]
100145909	sfrs3b; splicing factor, arginine/serine-rich 3b [KO:K12892]
436883	srsf5b; serine/arginine-rich splicing factor 5b [KO:K12893]
335396	srsf5a; serine/arginine-rich splicing factor 5a [KO:K12893]
406775	srsf6a; serine/arginine-rich splicing factor 6a [KO:K12893]
494133	srsf6b; serine/arginine-rich splicing factor 6b [KO:K12893]
321872	srsf4; serine/arginine-rich splicing factor 4 [KO:K12893]
402972	fb39b02; zgc:77155 [KO:K12896]
572211	srsf7; serine/arginine-rich splicing factor 7 [KO:K12896]
559273	ep300a; E1A binding protein p300 a [KO:K04498] [EC:2.3.1.48]
565612	ep300b; E1A binding protein p300 b [KO:K04498] [EC:2.3.1.48]
100535787	crebbp; CREB binding protein [KO:K04498] [EC:2.3.1.48]
30590	tp53; tumor protein p53 [KO:K04451]
561006	daxx; death-associated protein 6 [KO:K02308]
80973	cdk1; cyclin-dependent kinase 1 [KO:K02087] [EC:2.7.11.23 2.7.11.22]
406715	cdk2; cyclin-dependent kinase 2 [KO:K02206] [EC:2.7.11.22]
30488	ck2a2a; casein kinase 2 alpha 2a [KO:K03097] [EC:2.7.11.1]
30502	ck2a1; casein kinase 2 alpha 1 [KO:K03097] [EC:2.7.11.1]
415254	ck2a1; zgc:86598 [KO:K03097] [EC:2.7.11.1]
556379	ck2a2b; casein kinase 2 alpha 2b [KO:K03097] [EC:2.7.11.1]
30428	ck2b; casein kinase 2 beta [KO:K03115]
550401	hcfc2; host cell factor C2 [KO:K14966]
564853	hcfc1a; host cell factor C1a [KO:K14966]
565206	hcfc1b; host cell factor C1b [KO:K14966]
368882	tbp; TATA box binding protein [KO:K03120]
407713	tbpl2; TATA box binding protein like 2 [KO:K03120]
403035	tbpl1; TBP-like 1 [KO:K03120]
447818	taf6; TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor [KO:K03131]
557363	taf6l; TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor [KO:K03131]
334055	taf5l; TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor [KO:K03130]
641491	taf5; TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor [KO:K03130]
564106	si:dkey-219c3.2; K03129 transcription initiation factor TFIID subunit 4 [KO:K03129]
100149942	transcription initiation factor TFIID subunit 4-like; K03129 transcription initiation factor TFIID subunit 4 [KO:K03129]
100150678	novel protein similar to vertebrate TAF4 RNA polymerase II; K03129 transcription initiation factor TFIID subunit 4 [KO:K03129]
334474	taf3; TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto [KO:K14650]
324153	taf13; TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor [KO:K03127]
556710	taf10; TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor [KO:K03134]
404615	med8; mediator complex subunit 8 [KO:K15129]
81597	gtf2ird1; GTF2I repeat domain-containing 1 [KO:K03121]
560127	alyref; Aly/REF export factor [KO:K12881]
323865	nxf1; nuclear RNA export factor 1 [KO:K14284]
751719	zgc:153681; K14284 nuclear RNA export factor 1/2 [KO:K14284]
334619	fa14h03; zgc:110137 [KO:K15414]
406264	hnrpkl; heterogeneous nuclear ribonucleoprotein K, like [KO:K12886]
30783	mhc2a; major histocompatibility complex class II integral membrane alpha chain gene [KO:K06752]
30764	mhc2deb; major histocompatibility complex class II DEB gene [KO:K06752]
30763	mhc2dcb; major histocompatibility complex class II DCB gene [KO:K06752]
30762	mhc2dab; major histocompatibility complex class II DAB gene [KO:K06752]
654336	zgc:123077; K06752 major histocompatibility complex, class II [KO:K06752]
335509	a1; zgc:113912 [KO:K06752]
368614	si:dz48c11.3; si:busm1-48c11.3 [KO:K06752]
368615	MHCII; si:busm1-194e12.12 [KO:K06752]
368816	MHCII; si:busm1-194e12.8 [KO:K06752]
368877	si:dz266f07.1; si:busm1-266f07.1 [KO:K06752]
368878	MHCII; si:busm1-266f07.2 [KO:K06752]
571282	novel protein with a Class II histocompatibility antigen; K06752 major histocompatibility complex, class II [KO:K06752]
58113	cd74a; CD74 molecule, major histocompatibility complex, class II invariant chain a [KO:K06505]
100333043	antigen peptide transporter 1-like; K05653 ATP-binding cassette, subfamily B (MDR/TAP), member 2 [KO:K05653]
368771	abcb3l1; ATP-binding cassette, sub-family B (MDR/TAP), member 3 like 1 [KO:K05654]
64885	mhc1uea; major histocompatibility complex class I UEA [KO:K06751]
393557	mhc1uxa2; major histocompatibility complex class I UXA2 gene [KO:K06751]
619391	crfb5; cytokine receptor family member b5 [KO:K05130]
777653	crfb2; cytokine receptor family member b2 [KO:K05131]
30280	jak1; Janus kinase 1 [KO:K11217] [EC:2.7.10.2]
100536675	tyk2; tyrosine kinase 2 [KO:K11219] [EC:2.7.10.2]
30768	stat1a; signal transduction and activation of transcription 1a [KO:K11220]
368481	stat1b; signal transducer and activator of transcription 1b [KO:K11220]
403013	irf9; interferon regulatory factor 9 [KO:K04693]
406596	socs3b; suppressor of cytokine signaling 3b [KO:K04696]
405790	ifng1-2; interferon, gamma 1-2 [KO:K04687]
100329124	crfb13; cytokine receptor family member B13 [KO:K05132]
30307	jak2a; Janus kinase 2a [KO:K04447] [EC:2.7.10.2]
30298	jak2b; Janus kinase 2b [KO:K04447] [EC:2.7.10.2]
735295	faslg; Fas ligand (TNF superfamily, member 6) [KO:K04389]
768248	fas; Fas (TNF receptor superfamily, member 6) [KO:K04390]
406471	tnfrsf1a; tumor necrosis factor receptor superfamily, member 1a [KO:K03158]
562317	fadd; Fas (tnfrsf6)-associated via death domain [KO:K02373]
58022	casp8; caspase 8, apoptosis-related cysteine peptidase [KO:K04398] [EC:3.4.22.61]
557302	casp8l2; caspase 8, apoptosis-related cysteine peptidase, like 2 [KO:K04398] [EC:3.4.22.61]
140621	casp3a; caspase 3, apoptosis-related cysteine protease a [KO:K02187] [EC:3.4.22.56]
566604	casp3b; caspase 3, apoptosis-related cysteine protease b [KO:K02187] [EC:3.4.22.56]
415158	cycsb; cytochrome c, somatic b [KO:K08738]
58098	arntl1a; aryl hydrocarbon receptor nuclear translocator-like 1a [KO:K02296]
352935	arntl1b; aryl hydrocarbon receptor nuclear translocator-like 1b [KO:K02296]
30140	clock; clock [KO:K02223] [EC:2.3.1.48]
352927	clock3; clock homolog 3 (mouse) [KO:K02223] [EC:2.3.1.48]
140633	per2; period homolog 2 (Drosophila) [KO:K02633]
58107	per3; period homolog 3 (Drosophila) [KO:K02633]
406204	per1b; period homolog 1b (Drosophila) [KO:K02633]
563926	per1a; period homolog 1a (Drosophila) [KO:K02633]

Reference

PMID:12797447

Authors

Kobelt D, Lechmann M, Steinkasserer A

Title

The interaction between dendritic cells and herpes simplex virus-1.

Journal

Curr Top Microbiol Immunol 276:145-61 (2003)

Reference

PMID:12224508

Authors

Leib DA

Title

Counteraction of interferon-induced antiviral responses by herpes simplex viruses.

Journal

Curr Top Microbiol Immunol 269:171-85 (2002)

Reference

PMID:20036979

Authors

Martinez-Martin N, Viejo-Borbolla A

Title

Toll-like receptor-mediated recognition of herpes simplex virus.

Journal

Front Biosci (Schol Ed) 2:718-29 (2010)

Reference

PMID:10696424

Authors

Roizman B

Title

HSV gene functions: what have we learned that could be generally applicable to its near and distant cousins?

Journal

Acta Virol 43:75-80 (1999)

Reference

PMID:12224518

Authors

Bauer D, Tampe R

Title

Herpes viral proteins blocking the transporter associated with antigen processing TAP--from genes to function and structure.

Journal

Curr Top Microbiol Immunol 269:87-99 (2002)

Reference

PMID:18508584

Authors

Sandri-Goldin RM

Title

The many roles of the regulatory protein ICP27 during herpes simplex virus infection.

Journal

Front Biosci 13:5241-56 (2008)

Reference

PMID:12224517

Authors

Reits E, Griekspoor A, Neefjes J

Title

Herpes viral proteins manipulating the peptide transporter TAP.

Journal

Curr Top Microbiol Immunol 269:75-83 (2002)

Reference

PMID:15056211

Authors

Spear PG

Title

Herpes simplex virus: receptors and ligands for cell entry.

Journal

Cell Microbiol 6:401-10 (2004)

Reference

PMID:18596690

Authors

Umbach JL, Kramer MF, Jurak I, Karnowski HW, Coen DM, Cullen BR

Title

MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs.

Journal

Nature 454:780-3 (2008)

Reference

PMID:16076403

Authors

Ellermann-Eriksen S

Title

Macrophages and cytokines in the early defence against herpes simplex virus.

Journal

Virol J 2:59 (2005)

Reference

PMID:16297150

Authors

Novak N, Peng WM

Title

Dancing with the enemy: the interplay of herpes simplex virus with dendritic cells.

Journal

Clin Exp Immunol 142:405-10 (2005)

Reference

PMID:12525427

Authors

Koelle DM, Corey L

Title

Recent progress in herpes simplex virus immunobiology and vaccine research.

Journal

Clin Microbiol Rev 16:96-113 (2003)

Reference

PMID:14747533

Authors

Lin R, Noyce RS, Collins SE, Everett RD, Mossman KL

Title

The herpes simplex virus ICP0 RING finger domain inhibits IRF3- and IRF7-mediated activation of interferon-stimulated genes.

Journal

J Virol 78:1675-84 (2004)

Reference

PMID:14963113

Authors

Hagglund R, Roizman B

Title

Role of ICP0 in the strategy of conquest of the host cell by herpes simplex virus 1.

Journal

J Virol 78:2169-78 (2004)

Reference

PMID:10918307

Authors

Everett RD

Title

ICP0, a regulator of herpes simplex virus during lytic and latent infection.

Journal

Bioessays 22:761-70 (2000)

Reference

PMID:12826401

Authors

Wysocka J, Herr W

Title

The herpes simplex virus VP16-induced complex: the makings of a regulatory switch.

Journal

Trends Biochem Sci 28:294-304 (2003)

Reference

PMID:19694546

Authors

Paladino P, Mossman KL

Title

Mechanisms employed by herpes simplex virus 1 to inhibit the interferon response.

Journal

J Interferon Cytokine Res 29:599-607 (2009)

Reference

PMID:11070032

Authors

Bryant HE, Matthews DA, Wadd S, Scott JE, Kean J, Graham S, Russell WC, Clements JB

Title

Interaction between herpes simplex virus type 1 IE63 protein and cellular protein p32.

Journal

J Virol 74:11322-8 (2000)

Reference

PMID:10998601

Authors

Jackson PK, Eldridge AG, Freed E, Furstenthal L, Hsu JY, Kaiser BK, Reimann JD

Title

The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases.

Journal

Trends Cell Biol 10:429-39 (2000)

Reference

PMID:10364308

Authors

Long MC, Leong V, Schaffer PA, Spencer CA, Rice SA

Title

ICP22 and the UL13 protein kinase are both required for herpes simplex virus-induced modification of the large subunit of RNA polymerase II.

Journal

J Virol 73:5593-604 (1999)

Reference

PMID:15163721

Authors

Yokota S, Yokosawa N, Okabayashi T, Suzutani T, Miura S, Jimbow K, Fujii N

Title

Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 contributes to inhibition of the interferon signaling pathway.

Journal

J Virol 78:6282-6 (2004)

Reference

PMID:9499021

Authors

Kawaguchi Y, Van Sant C, Roizman B

Title

Eukaryotic elongation factor 1delta is hyperphosphorylated by the protein kinase encoded by the U(L)13 gene of herpes simplex virus 1.

Journal

J Virol 72:1731-6 (1998)

Reference

PMID:10196275

Authors

Bruni R, Fineschi B, Ogle WO, Roizman B

Title

A novel cellular protein, p60, interacting with both herpes simplex virus 1 regulatory proteins ICP22 and ICP0 is modified in a cell-type-specific manner and Is recruited to the nucleus after infection.

Journal

J Virol 73:3810-7 (1999)

Reference

PMID:19879619

Authors

Johnson KE, Knipe DM

Title

Herpes simplex virus-1 infection causes the secretion of a type I interferon-antagonizing protein and inhibits signaling at or before Jak-1 activation.

Journal

Virology 396:21-9 (2010)

Reference

PMID:15047834

Authors

Chee AV, Roizman B

Title

Herpes simplex virus 1 gene products occlude the interferon signaling pathway at multiple sites.

Journal

J Virol 78:4185-96 (2004)

Reference

PMID:17913820

Authors

Rasmussen SB, Sorensen LN, Malmgaard L, Ank N, Baines JD, Chen ZJ, Paludan SR

Title

Type I interferon production during herpes simplex virus infection is controlled by cell-type-specific viral recognition through Toll-like receptor 9, the mitochondrial antiviral signaling protein pathway, and novel recognition systems.

Journal

J Virol 81:13315-24 (2007)

Reference

PMID:21107701

Authors

Dufour F, Sasseville AM, Chabaud S, Massie B, Siegel RM, Langelier Y

Title

The ribonucleotide reductase R1 subunits of herpes simplex virus types 1 and 2 protect cells against TNFalpha- and FasL-induced apoptosis by interacting with caspase-8.

Journal

Apoptosis 16:256-71 (2011)

Reference

PMID:9621021

Authors

Schang LM, Phillips J, Schaffer PA

Title

Requirement for cellular cyclin-dependent kinases in herpes simplex virus replication and transcription.

Journal

J Virol 72:5626-37 (1998)

Reference

PMID:12844494

Authors

Medici MA, Sciortino MT, Perri D, Amici C, Avitabile E, Ciotti M, Balestrieri E, De Smaele E, Franzoso G, Mastino A

Title

Protection by herpes simplex virus glycoprotein D against Fas-mediated apoptosis: role of nuclear factor kappaB.

Journal

J Biol Chem 278:36059-67 (2003)

Reference

PMID:17222692

Authors

Nguyen ML, Blaho JA

Title

Apoptosis during herpes simplex virus infection.

Journal

Adv Virus Res 69:67-97 (2007)

KO pathway

ko05168

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Pathway (2)   
   KEGG MODULE (1)   
   BioSystems (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (173)   
   KEGG GENES (173)   
All databases (176)   

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