KEGG   PATHWAY: dya00062Help
Entry
dya00062                    Pathway                                
Name
Fatty acid elongation - Drosophila yakuba
Class
Metabolism; Lipid metabolism
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Pathway map
Fatty acid elongation
dya00062

All organismsOrtholog table
Module
Fatty acid biosynthesis, elongation, mitochondria [PATH:dya00062]
Fatty acid biosynthesis, elongation, endoplasmic reticulum [PATH:dya00062]
Organism
Drosophila yakuba [GN:dya]
Gene
Dyak_yip2; GE18877 gene product from transcript GE18877-RA [KO:K07508] [EC:2.3.1.16]
GE11519 gene product from transcript GE11519-RA; K07509 acetyl-CoA acyltransferase [EC:2.3.1.16] [KO:K07509] [EC:2.3.1.16]
GE10479 gene product from transcript GE10479-RA; K07515 enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211] [KO:K07515] [EC:1.1.1.211 4.2.1.17]
GE13337 gene product from transcript GE13337-RA; K07511 enoyl-CoA hydratase [EC:4.2.1.17] [KO:K07511] [EC:4.2.1.17]
GE13334 gene product from transcript GE13334-RA; K07512 mitochondrial trans-2-enoyl-CoA reductase [EC:1.3.1.38] [KO:K07512] [EC:1.3.1.38]
GE17436 gene product from transcript GE17436-RA; K01074 palmitoyl-protein thioesterase [EC:3.1.2.22] [KO:K01074] [EC:3.1.2.22]
GE18522 gene product from transcript GE18522-RA; K01074 palmitoyl-protein thioesterase [EC:3.1.2.22] [KO:K01074] [EC:3.1.2.22]
GE20238 gene product from transcript GE20238-RA; K10249 elongation of very long chain fatty acids protein 4 [EC:2.3.1.199] [KO:K10249] [EC:2.3.1.199]
GE20239 gene product from transcript GE20239-RA; K10249 elongation of very long chain fatty acids protein 4 [EC:2.3.1.199] [KO:K10249] [EC:2.3.1.199]
GE15745 gene product from transcript GE15745-RA; K10251 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330] [KO:K10251] [EC:1.1.1.330 1.1.1.62]
GE12555 gene product from transcript GE12555-RA; K10703 very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase [EC:4.2.1.134] [KO:K10703] [EC:4.2.1.134]
GE21388 gene product from transcript GE21388-RA; K10258 very-long-chain enoyl-CoA reductase [EC:1.3.1.93] [KO:K10258] [EC:1.3.1.93]
Compound
C00024  
Acetyl-CoA
C00040  
Acyl-CoA
C00083  
Malonyl-CoA
C00136  
Butanoyl-CoA
C00154  
Palmitoyl-CoA
C00162  
Fatty acid
C00249  
Hexadecanoic acid
C00264  
3-Oxoacyl-CoA
C00605  
2,3-Dehydroacyl-CoA
C00638  
Long-chain fatty acid
C00640  
(3S)-3-Hydroxyacyl-CoA
C00658  
trans-2,3-Dehydroacyl-CoA
C01832  
Lauroyl-CoA
C01944  
Octanoyl-CoA
C02593  
Tetradecanoyl-CoA
C02843  
Long-chain acyl-CoA
C03221  
2-trans-Dodecenoyl-CoA
C05258  
(S)-3-Hydroxyhexadecanoyl-CoA
C05259  
3-Oxopalmitoyl-CoA
C05260  
(S)-3-Hydroxytetradecanoyl-CoA
C05261  
3-Oxotetradecanoyl-CoA
C05262  
(S)-3-Hydroxydodecanoyl-CoA
C05263  
3-Oxododecanoyl-CoA
C05264  
(S)-Hydroxydecanoyl-CoA
C05265  
3-Oxodecanoyl-CoA
C05266  
(S)-3-Hydroxyoctanoyl-CoA
C05267  
3-Oxooctanoyl-CoA
C05268  
(S)-Hydroxyhexanoyl-CoA
C05269  
3-Oxohexanoyl-CoA
C05270  
Hexanoyl-CoA
C05271  
trans-Hex-2-enoyl-CoA
C05272  
trans-Hexadec-2-enoyl-CoA
C05273  
trans-Tetradec-2-enoyl-CoA
C05274  
Decanoyl-CoA
C05275  
trans-Dec-2-enoyl-CoA
C05276  
trans-Oct-2-enoyl-CoA
Reference
PMID:4387390
  Authors
Seubert W, Lamberts I, Kramer R, Ohly B
  Title
On the mechanism of malonyl-CoA-independent fatty acid synthesis. I. The mechanism of elongation of long-chain fatty acids by acetyl-CoA.
  Journal
Biochim Biophys Acta 164:498-517 (1968)
Reference
PMID:7150615
  Authors
El-Fakhri M, Middleton B
  Title
The existence of an inner-membrane-bound, long acyl-chain-specific 3-hydroxyacyl-CoA dehydrogenase in mammalian mitochondria.
  Journal
Biochim Biophys Acta 713:270-9 (1982)
Reference
PMID:8190743
  Authors
Cassagne C, Lessire R, Bessoule JJ, Moreau P, Creach A, Schneider F, Sturbois B
  Title
Biosynthesis of very long chain fatty acids in higher plants.
  Journal
Prog Lipid Res 33:55-69 (1994)
Reference
  Authors
Jakobsson A, Westerberg R, Jacobsson A.
  Title
Fatty acid elongases in mammals: their regulation and roles in metabolism.
  Journal
Prog Lipid Res 45:237-49 (2006)
Reference
  Authors
Blacklock BJ, Jaworski JG
  Title
Substrate specificity of Arabidopsis 3-ketoacyl-CoA synthases.
  Journal
Biochem Biophys Res Commun 346:583-90 (2006)
Reference
  Authors
Shepherd T, Wynne Griffiths D
  Title
The effects of stress on plant cuticular waxes.
  Journal
New Phytol 171:469-99 (2006)
Reference
  Authors
Riezman H
  Title
The long and short of fatty acid synthesis.
  Journal
Cell 130:587-8 (2007)
Reference
  Authors
Raffaele S, Leger A, Roby D
  Title
Very long chain fatty acid and lipid signaling in the response of plants to pathogens.
  Journal
Plant Signal Behav 4:94-9 (2009)
KO pathway
 
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