KEGG   PATHWAY: eas00290
Entry
eas00290                    Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Enterobacter soli
Class
Metabolism; Amino acid metabolism
Pathway map
eas00290  Valine, leucine and isoleucine biosynthesis
eas00290

Module
eas_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:eas00290]
eas_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:eas00290]
eas_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:eas00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Enterobacter soli [GN:eas]
Gene
Entas_3792  Pyridoxal-5'-phosphate-dependent protein beta subunit [KO:K01754] [EC:4.3.1.19]
Entas_4298  threonine dehydratase, biosynthetic [KO:K01754] [EC:4.3.1.19]
Entas_0674  3-isopropylmalate dehydratase large subunit [KO:K01703] [EC:4.2.1.33 4.2.1.35]
Entas_0673  3-isopropylmalate dehydratase small subunit [KO:K01704] [EC:4.2.1.33 4.2.1.35]
Entas_0675  3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
Entas_0033  acetolactate synthase, large subunit, biosynthetic type [KO:K01652] [EC:2.2.1.6]
Entas_0678  acetolactate synthase, large subunit, biosynthetic type [KO:K01652] [EC:2.2.1.6]
Entas_4302  acetolactate synthase, large subunit, biosynthetic type [KO:K01652] [EC:2.2.1.6]
Entas_0034  amino acid-binding ACT domain protein [KO:K01653] [EC:2.2.1.6]
Entas_0679  acetolactate synthase, small subunit [KO:K01653] [EC:2.2.1.6]
Entas_4301  acetolactate synthase 2 regulatory subunit [KO:K11258] [EC:2.2.1.6]
Entas_4296  Ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
Entas_4299  Dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
Entas_4300  branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
Entas_0170  aminotransferase class I and II [KO:K00835] [EC:2.6.1.66]
Entas_3006  aminotransferase class I and II [KO:K14260] [EC:2.6.1.66 2.6.1.2]
Entas_0676  2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Entas_3397  2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
PMID:15292141
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
eas00260  Glycine, serine and threonine metabolism
eas00280  Valine, leucine and isoleucine degradation
eas00620  Pyruvate metabolism
KO pathway
ko00290   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG GENES (18)   
All databases (19)   

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