KEGG   PATHWAY: ec00622
Entry
ec00622                     Pathway                                
Name
Xylene degradation
Class
Metabolism; Xenobiotics biodegradation and metabolism
Pathway map
ec00622  Xylene degradation
ec00622

Module
M00419  Cymene degradation, p-cymene => p-cumate [PATH:ec00622]
M00537  Xylene degradation, xylene => methylbenzoate [PATH:ec00622]
M00539  Cumate degradation, p-cumate => 2-oxopent-4-enoate + 2-methylpropanoate [PATH:ec00622]
M00551  Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol [PATH:ec00622]
M00569  Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA [PATH:ec00622]
Other DBs
GO: 0042184
UMBBD: mxy oxy pxy pcy tol
Enzyme
1.1.1.90   
1.13.11.2   
1.14.12.25   
1.14.15.25   
1.14.15.26   
1.2.1.10   
1.2.1.28   
1.2.1.29   
1.2.1.7   
1.2.1.85   
1.2.1.87   
1.3.1.58   
1.3.1.67   
1.3.1.68   
3.7.1.25   
3.7.1.9   
4.1.1.77   
4.1.3.39   
4.1.3.43   
4.2.1.132   
4.2.1.80   
5.3.2.6   
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00084  Acetaldehyde
C00100  Propanoyl-CoA
C00479  Propanal
C00596  2-Hydroxy-2,4-pentadienoate
C01454  Toluate
C02923  2,3-Dihydroxytoluene
C03589  4-Hydroxy-2-oxopentanoate
C06210  2-Hydroxy-6-keto-2,4-heptadienoate
C06575  p-Cymene
C06576  p-Cumic alcohol
C06577  4-Isopropylbenzaldehyde
C06578  p-Cumate
C06579  cis-2,3-Dihydroxy-2,3-dihydro-p-cumate
C06580  2,3-Dihydroxy-p-cumate
C06581  2-Hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate
C06582  2-Hydroxy-6-oxo-7-methylocta-2,4-dienoate
C06720  1,6-Dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate
C06729  cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate
C06730  4-Methylcatechol
C06731  1,2-Dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate
C06756  p-Xylene
C06757  4-Methylbenzyl alcohol
C06758  p-Tolualdehyde
C06760  2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde
C06762  4-Hydroxy-2-oxohexanoic acid
C07208  m-Xylene
C07209  3-Methylbenzaldehyde
C07211  m-Methylbenzoate
C07212  o-Xylene
C07213  2-Methylbenzyl alcohol
C07214  2-Methylbenzaldehyde
C07215  o-Toluate
C07216  3-Methylbenzyl alcohol
C07478  2-Hydroxy-5-methyl-cis,cis-muconate
C07479  2-Oxo-5-methyl-cis-muconate
C11354  2-Hydroxy-cis-hex-2,4-dienoate
Reference
PMID:11375157
  Authors
Haddad S, Eby DM, Neidle EL.
  Title
Cloning and expression of the benzoate dioxygenase genes from Rhodococcus sp. strain 19070.
  Journal
Appl Environ Microbiol 67:2507-14 (2001)
DOI:10.1128/AEM.67.6.2507-2514.2001
Reference
PMID:7768806
  Authors
Kim E, Zylstra GJ
  Title
Molecular and biochemical characterization of two meta-cleavage dioxygenases involved in biphenyl and m-xylene degradation by Beijerinckia sp. strain B1.
  Journal
J Bacteriol 177:3095-103 (1995)
DOI:10.1128/JB.177.11.3095-3103.1995
Reference
PMID:15127183
  Authors
Morasch B, Schink B, Tebbe CC, Meckenstock RU
  Title
Degradation of o-xylene and m-xylene by a novel sulfate-reducer belonging to the genus Desulfotomaculum.
  Journal
Arch Microbiol 181:407-17 (2004)
DOI:10.1007/s00203-004-0672-6
Reference
PMID:9150211
  Authors
Eaton RW.
  Title
p-Cymene catabolic pathway in Pseudomonas putida F1: cloning and characterization of DNA encoding conversion of p-cymene to p-cumate.
  Journal
J Bacteriol 179:3171-80 (1997)
DOI:10.1128/JB.179.10.3171-3180.1997
Reference
PMID:8631713
  Authors
Eaton RW.
  Title
p-Cumate catabolic pathway in Pseudomonas putida Fl: cloning and characterization of DNA carrying the cmt operon.
  Journal
J Bacteriol 178:1351-62 (1996)
DOI:10.1128/JB.178.5.1351-1362.1996
Related
pathway
ec00010  Glycolysis / Gluconeogenesis
ec00020  Citrate cycle (TCA cycle)
ec00623  Toluene degradation
ec00640  Propanoate metabolism

  All links  
Chemical reaction (22)   
   KEGG ENZYME (22)   
All databases (22)   

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