KEGG   PATHWAY: eci00250
Entry
eci00250                    Pathway                                
Name
Alanine, aspartate and glutamate metabolism - Escherichia coli O18:K1:H7 UTI89 (UPEC)
Class
Metabolism; Amino acid metabolism
Pathway map
eci00250  Alanine, aspartate and glutamate metabolism
eci00250

Module
eci_M00027  GABA (gamma-Aminobutyrate) shunt [PATH:eci00250]
Other DBs
GO: 0006522 0006531 0006536
Organism
Escherichia coli O18:K1:H7 UTI89 (UPEC) [GN:eci]
Gene
UTI89_C1000  aspC; aspartate transaminase [KO:K00813] [EC:2.6.1.1]
UTI89_C2896  nadB; L-aspartate oxidase [KO:K00278] [EC:1.4.3.16]
UTI89_C1963  ansA; L-asparaginase I [KO:K01424] [EC:3.5.1.1]
UTI89_C3346  ansB; L-asparaginase II precursor [KO:K01424] [EC:3.5.1.1]
UTI89_C0831  ybiK; putative L-asparaginase precursor [KO:K13051] [EC:3.5.1.1 3.4.19.5]
UTI89_C4299  asnA; asparagine synthetase A [KO:K01914] [EC:6.3.1.1]
UTI89_C0668  asnB; glutamine-hydrolyzing asparagine synthetase B [KO:K01953] [EC:6.3.5.4]
UTI89_C0259  hypothetical protein [KO:K13566] [EC:3.5.1.3]
UTI89_C2572  putative aminotransferase [KO:K14260] [EC:2.6.1.66 2.6.1.2]
UTI89_C4736  aspA; aspartate ammonia-lyase (aspartase) [KO:K01744] [EC:4.3.1.1]
UTI89_C3604  argG; argininosuccinate synthetase [KO:K01940] [EC:6.3.4.5]
UTI89_C4551  argH; argininosuccinate lyase [KO:K01755] [EC:4.3.2.1]
UTI89_C4777  purA; PurA, subunit of adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
UTI89_C1260  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
UTI89_C4851  pyrB; PyrB, subunit of aspartatetranscarbamylase, catalytic subunit and aspartate-carbamoyltransferase [KO:K00609] [EC:2.1.3.2]
UTI89_C4850  pyrI; PyrI, subunit of regulatory subunit and aspartate-carbamoyltransferase [KO:K00610]
UTI89_C1707  gadB; glutamate decarboxylase beta [KO:K01580] [EC:4.1.1.15]
UTI89_C4049  gadA; glutamate decarboxylase alpha [KO:K01580] [EC:4.1.1.15]
UTI89_C3017  gabT; 4-aminobutyrate aminotransferase [KO:K07250] [EC:2.6.1.19 2.6.1.22 2.6.1.48]
UTI89_C3016  gabD; [NADP+] succinate-semialdehyde dehydrogenase [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
UTI89_C1744  yneI; aldehyde-dehydrogenase like protein YneI [KO:K08324] [EC:1.2.1.16 1.2.1.24]
UTI89_C3649  gltB; glutamate synthase [NADPH] large chain precursor [KO:K00265] [EC:1.4.1.13]
UTI89_C3650  gltD; glutamate synthase small subunit [KO:K00266] [EC:1.4.1.13]
UTI89_C1957  gdhA; NADP-specific glutamate dehydrogenase [KO:K00262] [EC:1.4.1.4]
UTI89_C1077  putA; delta-1-pyrroline-5-carboxylate dehydrogenase [KO:K13821] [EC:1.5.5.2 1.2.1.88]
UTI89_C4459  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
UTI89_C0037  carB; Carbamoyl-phosphate synthase large chain [KO:K01955] [EC:6.3.5.5]
UTI89_C0036  carA; carbamoyl-phosphate synthase small chain [KO:K01956] [EC:6.3.5.5]
UTI89_C0516  ybaS; probable glutaminase YbaS [KO:K01425] [EC:3.5.1.2]
UTI89_C1743  yneH; putative glutaminase [KO:K01425] [EC:3.5.1.2]
UTI89_C4281  glmS; L-glutamine:D-fructose-6-phosphate aminotransferase [KO:K00820] [EC:2.6.1.16]
UTI89_C2596  purF; amidophosphoribosyltransferase = PRPP amidotransferase [KO:K00764] [EC:2.4.2.14]
Compound
C00014  Ammonia
C00022  Pyruvate
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00036  Oxaloacetate
C00041  L-Alanine
C00042  Succinate
C00049  L-Aspartate
C00064  L-Glutamine
C00122  Fumarate
C00152  L-Asparagine
C00158  Citrate
C00169  Carbamoyl phosphate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00352  D-Glucosamine 6-phosphate
C00402  D-Aspartate
C00438  N-Carbamoyl-L-aspartate
C00940  2-Oxoglutaramate
C01042  N-Acetyl-L-aspartate
C02362  2-Oxosuccinamate
C03090  5-Phosphoribosylamine
C03406  N-(L-Arginino)succinate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03912  (S)-1-Pyrroline-5-carboxylate
C12270  N-Acetylaspartylglutamate
C20775  beta-Citryl-L-glutamate
C20776  N-Acetylaspartylglutamylglutamate
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
PMID:9687539
  Authors
Wu G
  Title
Intestinal mucosal amino acid catabolism.
  Journal
J Nutr 128:1249-52 (1998)
DOI:10.1093/jn/128.8.1249
Related
pathway
eci00010  Glycolysis / Gluconeogenesis
eci00020  Citrate cycle (TCA cycle)
eci00220  Arginine biosynthesis
eci00230  Purine metabolism
eci00240  Pyrimidine metabolism
eci00260  Glycine, serine and threonine metabolism
eci00261  Monobactam biosynthesis
eci00300  Lysine biosynthesis
eci00330  Arginine and proline metabolism
eci00340  Histidine metabolism
eci00410  beta-Alanine metabolism
eci00460  Cyanoamino acid metabolism
eci00470  D-Amino acid metabolism
eci00480  Glutathione metabolism
eci00520  Amino sugar and nucleotide sugar metabolism
eci00620  Pyruvate metabolism
eci00630  Glyoxylate and dicarboxylate metabolism
eci00650  Butanoate metabolism
eci00660  C5-Branched dibasic acid metabolism
eci00760  Nicotinate and nicotinamide metabolism
eci00770  Pantothenate and CoA biosynthesis
eci00860  Porphyrin metabolism
eci00910  Nitrogen metabolism
KO pathway
ko00250   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (32)   
   KEGG GENES (32)   
All databases (33)   

Download RDF
DBGET integrated database retrieval system