KEGG   PATHWAY: ecv00230
Entry
ecv00230                    Pathway                                
Name
Purine metabolism - Escherichia coli APEC O1 (APEC)
Class
Metabolism; Nucleotide metabolism
Pathway map
ecv00230  Purine metabolism
ecv00230

Module
ecv_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ecv00230]
ecv_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ecv00230]
ecv_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ecv00230]
ecv_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ecv00230]
ecv_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ecv00230]
Other DBs
GO: 0006163 0042278
Organism
Escherichia coli APEC O1 (APEC) [GN:ecv]
Gene
APECO1_3379  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
APECO1_3067  nudE; ADP-ribose diphosphatase [KO:K08312] [EC:3.6.1.-]
APECO1_1998  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
APECO1_3083  yhfW; putative phosphomutase [KO:K01839] [EC:5.4.2.7]
APECO1_1376  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
APECO1_323  prsA; phosphoribosylpyrophosphate synthase [KO:K00948] [EC:2.7.6.1]
APECO1_4252  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
APECO1_2470  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
APECO1_4069  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
APECO1_899  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
APECO1_3974  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
APECO1_4070  purM; phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
APECO1_1493  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
APECO1_1492  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
APECO1_4081  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
APECO1_213  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
APECO1_2469  purH; bifunctional AICAR formyltransferase/IMP cyclohydrolase PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
APECO1_1546  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
APECO1_1535  ushA; UDP-sugar hydrolase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
APECO1_3779  surE; acid phosphatase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
APECO1_1397  nagD; putative N-acetylglucosamine metabolism protein [KO:K02566] [EC:3.1.3.5]
APECO1_3065  yrfG; putative hydrolase [KO:K20881] [EC:3.1.3.-]
APECO1_1538  gsk; inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
APECO1_4138  xapA; xanthosine phosphorylase [KO:K03783] [EC:2.4.2.1]
APECO1_1997  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
APECO1_1617  conserved hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
APECO1_3937  yfiH; conserved hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
APECO1_1860  hpt; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
APECO1_4018  guaB; inositol-5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
APECO1_4006  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
APECO1_1985  yjjX; conserved hypothetical protein [KO:K01529] [EC:3.6.1.73]
APECO1_3567  yggV; putative ribosomal protein [KO:K01519] [EC:3.6.1.66]
APECO1_1731  gpt; xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
APECO1_3659  xanthine dehydrogenase, molybdenum binding subunit [KO:K00087] [EC:1.17.1.4]
APECO1_3658  ygeT; xanthine dehydrogenase, FAD binding subunit [KO:K13479] [EC:1.17.1.4]
APECO1_4019  guaA; bifunctional GMP synthase/glutamine amidotransferase protein [KO:K01951] [EC:6.3.5.2]
APECO1_1884  guaC; guanosine 5'-monophosphate oxidoreductase [KO:K00364] [EC:1.7.1.7]
APECO1_3643  ygfP; guanine deaminase [KO:K01487] [EC:3.5.4.3]
APECO1_2813  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
APECO1_4326  nrdA; ribonucleotide-diphosphate reductase alpha subunit [KO:K00525] [EC:1.17.4.1]
APECO1_3846  nrdE; ribonucleoside-diphosphate reductase 2 alpha chain [KO:K00525] [EC:1.17.4.1]
APECO1_4325  nrdB; ribonucleotide-diphosphate reductase beta subunit [KO:K00526] [EC:1.17.4.1]
APECO1_3845  nrdF; ribonucleoside-diphosphate reductase 2 beta chain [KO:K00526] [EC:1.17.4.1]
APECO1_2154  nrdD; anaerobic ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
APECO1_1825  dgt; deoxyguanosine triphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
APECO1_4273  yfbR; putative alpha helix protein [KO:K08722] [EC:3.1.3.89]
APECO1_2048  yfdR; conserved hypothetical protein [KO:K06952] [EC:3.1.3.89]
APECO1_3868  yfdR; conserved hypothetical protein [KO:K06952] [EC:3.1.3.89]
APECO1_2811  spoT; guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
APECO1_2694  gppA; guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
APECO1_4067  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
APECO1_3747  relA; (p)ppGpp synthetase I/GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
APECO1_2672  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
APECO1_2215  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
APECO1_706  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
APECO1_1068  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
APECO1_3736  ygdH; conserved hypothetical protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
APECO1_2787  ade; cryptic adenine deaminase [KO:K01486] [EC:3.5.4.2]
APECO1_2173  cpdB; 2':3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
APECO1_1541  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
APECO1_3749  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
APECO1_3381  icc; regulator of lacZ [KO:K03651] [EC:3.1.4.53]
APECO1_1933  apaH; bis(5'-nucleosyl)-tetraphosphatase, symmetrical [KO:K01525] [EC:3.6.1.41]
APECO1_37732  cysC; sulfate adenylyltransferase subunit 1 [KO:K00860] [EC:2.7.1.25]
APECO1_3773  cysN; sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
APECO1_3772  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
APECO1_1005  yedX; conserved hypothetical protein [KO:K07127] [EC:3.5.2.17]
APECO1_1503  allB; allantoinase [KO:K01466] [EC:3.5.2.5]
APECO1_1499  allC; N-carbamoyl-L-amino acid amidohydrolase [KO:K02083] [EC:3.5.3.9]
APECO1_1500  ylbA; conserved hypothetical protein [KO:K14977] [EC:3.5.3.26]
APECO1_1509  allA; ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
APECO1_1498  allD; ureidoglycolate dehydrogenase [KO:K00073] [EC:1.1.1.350]
APECO1_3652  yqeA; putative amino acid kinase [KO:K00926] [EC:2.7.2.2]
APECO1_2636  carbamate kinase-like protein [KO:K00926] [EC:2.7.2.2]
APECO1_2143  carbamate kinase [KO:K00926] [EC:2.7.2.2]
APECO1_1668  yahI; putative carbamate kinase-like protein [KO:K00926] [EC:2.7.2.2]
APECO1_1494  arcC; putative carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ecv00030  Pentose phosphate pathway
ecv00220  Arginine biosynthesis
ecv00250  Alanine, aspartate and glutamate metabolism
ecv00260  Glycine, serine and threonine metabolism
ecv00340  Histidine metabolism
ecv00630  Glyoxylate and dicarboxylate metabolism
ecv00730  Thiamine metabolism
ecv00740  Riboflavin metabolism
ecv00790  Folate biosynthesis
KO pathway
ko00230   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (77)   
   KEGG GENES (77)   
All databases (78)   

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