KEGG   PATHWAY: eko00630
Entry
eko00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Escherichia coli KO11FL
Class
Metabolism; Carbohydrate metabolism
Pathway map
eko00630  Glyoxylate and dicarboxylate metabolism
eko00630

Module
eko_M00012  Glyoxylate cycle [PATH:eko00630]
eko_M00621  Glycine cleavage system [PATH:eko00630]
Other DBs
GO: 0046487 0043648
Organism
Escherichia coli KO11FL [GN:eko]
Gene
EKO11_4310  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
EKO11_4251  acetate/CoA ligase [KO:K01895] [EC:6.2.1.1]
EKO11_0745  malate synthase G [KO:K01638] [EC:2.3.3.9]
EKO11_4311  malate synthase A [KO:K01638] [EC:2.3.3.9]
EKO11_0488  malate dehydrogenase, NAD-dependent [KO:K00024] [EC:1.1.1.37]
EKO11_3159  citrate synthase I [KO:K01647] [EC:2.3.3.1]
EKO11_2575  aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
EKO11_3115  aconitate hydratase domain-containing protein [KO:K01681] [EC:4.2.1.3]
EKO11_3798  aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
EKO11_0896  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
EKO11_0815  methylmalonyl-CoA mutase, large subunit [KO:K01847] [EC:5.4.99.2]
EKO11_0741  glycolate oxidase, subunit GlcD [KO:K00104] [EC:1.1.99.14]
EKO11_0742  FAD linked oxidase domain protein [KO:K11472] [EC:1.1.99.14]
EKO11_0743  protein of unknown function DUF224 cysteine-rich region domain protein [KO:K11473] [EC:1.1.99.14]
EKO11_2043  Catalase [KO:K03781] [EC:1.11.1.6]
EKO11_2800  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
EKO11_0175  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
EKO11_0360  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
EKO11_4492  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
EKO11_1182  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
EKO11_0828  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
EKO11_0826  glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
EKO11_3800  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
EKO11_0827  glycine cleavage system H protein [KO:K02437]
EKO11_3339  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
EKO11_3338  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
EKO11_3337  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
EKO11_0594  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
EKO11_0595  glycerate kinase [KO:K00865] [EC:2.7.1.165]
EKO11_3333  glycerate kinase [KO:K00865] [EC:2.7.1.165]
EKO11_2403  Aldehyde Dehydrogenase [KO:K07248] [EC:1.2.1.22 1.2.1.21]
EKO11_0969  lactaldehyde reductase [KO:K00048] [EC:1.1.1.77]
EKO11_0657  hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit [KO:K03779] [EC:4.2.1.32]
EKO11_0656  hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit [KO:K03780] [EC:4.2.1.32]
EKO11_1973  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
EKO11_1920  2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
EKO11_4462  molybdopterin oxidoreductase Fe4S4 region [KO:K00123] [EC:1.17.1.9]
EKO11_4463  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
EKO11_4464  formate dehydrogenase, beta subunit [KO:K00124]
EKO11_4465  formate dehydrogenase, gamma subunit [KO:K00127]
EKO11_2620  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
EKO11_1345  oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
eko00010  Glycolysis / Gluconeogenesis
eko00020  Citrate cycle (TCA cycle)
eko00030  Pentose phosphate pathway
eko00053  Ascorbate and aldarate metabolism
eko00071  Fatty acid degradation
eko00230  Purine metabolism
eko00250  Alanine, aspartate and glutamate metabolism
eko00260  Glycine, serine and threonine metabolism
eko00620  Pyruvate metabolism
eko00750  Vitamin B6 metabolism
eko00910  Nitrogen metabolism
KO pathway
ko00630   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (42)   
   KEGG GENES (42)   
All databases (43)   

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