KEGG PATHWAY: eum00630

PATHWAY: eum00630

Entry

eum00630 Pathway

Name

Glyoxylate and dicarboxylate metabolism - Escherichia coli O17:K52:H18 UMN026 (ExPEC)

Class

Metabolism; Carbohydrate metabolism

Pathway map

eum00630

Glyoxylate and dicarboxylate metabolism

Module

eum_M00012	Glyoxylate cycle [PATH:eum00630]
eum_M00373	Ethylmalonyl pathway [PATH:eum00630]
eum_M00532	Photorespiration [PATH:eum00630]

Organism

Escherichia coli O17:K52:H18 UMN026 (ExPEC) [GN:eum]

Gene

ECUMN_4541	aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
ECUMN_4540	aceB; malate synthase [KO:K01638] [EC:2.3.3.9]
ECUMN_3451	glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
ECUMN_3710	mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
ECUMN_0798	gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
ECUMN_0856	ybhJ; hypothetical protein [KO:K01681] [EC:4.2.1.- 4.2.1.3]
ECUMN_1578	acnA; aconitate hydratase [KO:K01681] [EC:4.2.1.- 4.2.1.3]
ECUMN_0115	acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.99 4.2.1.3]
ECUMN_2562	atoB; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
ECUMN_3172	yqeF; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
ECUMN_3261	yliK; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
ECUMN_3455	glcD; glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.3.15]
ECUMN_3454	glcE; glycolate oxidase FAD binding subunit [KO:K11472]
ECUMN_3453	glcF; glycolate oxidase iron-sulfur subunit [KO:K11473]
ECUMN_2021	katE; hydroperoxidase II [KO:K03781] [EC:1.11.1.6]
ECUMN_3843	gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
ECUMN_4393	glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
ECUMN_2871	glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
ECUMN_3245	gcvH; glycine cleavage system protein H [KO:K02437]
ECUMN_0548	gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
ECUMN_0549	hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
ECUMN_3607	garR; tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
ECUMN_0550	glxR; tartronate semialdehyde reductase, NADH-dependent [KO:K00042] [EC:1.1.1.60]
ECUMN_0554	glxK; glycerate kinase II [KO:K00865] [EC:2.7.1.31]
ECUMN_3606	garK; glycerate kinase I [KO:K00865] [EC:2.7.1.31]
ECUMN_1207	ycdW; 2-ketoacid reductase [KO:K12972] [EC:1.1.1.81 1.1.1.79]
ECUMN_1663	aldA; aldehyde dehydrogenase A [KO:K07248] [EC:1.2.1.21 1.2.1.22]
ECUMN_3128	fucO; L-1,2-propanediol oxidoreductase [KO:K00048] [EC:1.1.1.77]
ECUMN_3544	ttdA; tartrate dehydratase subunit alpha [KO:K03779] [EC:4.2.1.32]
ECUMN_3545	ttdB; L(+)-tartrate dehydratase subunit beta [KO:K03780] [EC:4.2.1.32]
ECUMN_2090	yeaU; putative tartrate dehydrogenase [KO:K07246] [EC:1.1.1.83 4.1.1.73 1.1.1.93]
ECUMN_2147	eda; keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.3.16 4.1.2.14]
ECUMN_4615	fdhF; formate dehydrogenase-H, selenopolypeptide subunit [KO:K00123] [EC:1.2.1.2]
ECUMN_4424	fdoG; formate dehydrogenase-O, large subunit [KO:K00123] [EC:1.2.1.2]
ECUMN_4423	fdoH; formate dehydrogenase-O, Fe-S subunit [KO:K00124]
ECUMN_4422	fdoI; formate dehydrogenase-O subunit gamma [KO:K00127]
ECUMN_1727	fdnG; formate dehydrogenase-N subunit alpha, nitrate-inducible [KO:K08348] [EC:1.2.1.2]
ECUMN_1729	fdnH; formate dehydrogenase-N, Fe-S subunit beta, nitrate-inducible [KO:K08349]
ECUMN_1730	fdnI; formate dehydrogenase-N subunit gamma [KO:K08350]
ECUMN_1529	purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
ECUMN_2702	oxc; putative oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]

Compound

C00007	Oxygen
C00011	CO2
C00014	NH3
C00022	Pyruvate
C00024	Acetyl-CoA
C00025	L-Glutamate
C00026	2-Oxoglutarate
C00027	Hydrogen peroxide
C00036	Oxaloacetate
C00037	Glycine
C00042	Succinate
C00048	Glyoxylate
C00058	Formate
C00064	L-Glutamine
C00065	L-Serine
C00091	Succinyl-CoA
C00100	Propanoyl-CoA
C00136	Butanoyl-CoA
C00149	(S)-Malate
C00158	Citrate
C00160	Glycolate
C00168	Hydroxypyruvate
C00197	3-Phospho-D-glycerate
C00209	Oxalate
C00258	D-Glycerate
C00266	Glycolaldehyde
C00311	Isocitrate
C00313	Oxalyl-CoA
C00332	Acetoacetyl-CoA
C00417	cis-Aconitate
C00552	meso-Tartaric acid
C00683	(S)-Methylmalonyl-CoA
C00798	Formyl-CoA
C00877	Crotonoyl-CoA
C00888	Pentanoyl-CoA
C00898	(R,R)-Tartaric acid
C00975	Dihydroxyfumarate
C00988	2-Phosphoglycolate
C01127	4-Hydroxy-2-oxoglutarate
C01146	2-Hydroxy-3-oxopropanoate
C01182	D-Ribulose 1,5-bisphosphate
C01213	(R)-Methylmalonyl-CoA
C01380	Ethylene glycol
C01989	3-Ethylmalate
C01990	3-Oxalomalate
C02123	3-Propylmalate
C02405	Formyl phosphate
C03217	2-Hydroxy-3-oxoadipate
C03459	2-Hydroxy-3-oxosuccinate
C03548	trans-2,3-Epoxysuccinate
C03561	(R)-3-Hydroxybutanoyl-CoA
C04348	(3S)-3-Carboxy-3-hydroxypropanoyl-CoA
C06027	L-erythro-3-Methylmalyl-CoA
C06028	Mesaconyl-CoA
C06049	N-Formylderivatives
C18026	(2S)-Ethylmalonyl-CoA
C18324	(2S)-Methylsuccinyl-CoA
C20238	(2R)-Ethylmalonyl-CoA

Reference

PMID:10978349 (EC5.3.1.22)

Authors

Njau RK, Herndon CA, Hawes JW.

Title

Novel beta -hydroxyacid dehydrogenases in Escherichia coli and Haemophilusinfluenzae.

Journal

J Biol Chem 275:38780-6 (2000)

Reference

PMID:18065535

Authors

Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G

Title

Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.

Journal

J Bacteriol 190:1366-74 (2008)

Reference

PMID:18819910

Authors

Erb TJ, Retey J, Fuchs G, Alber BE

Title

Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.

Journal

J Biol Chem 283:32283-93 (2008)

KO pathway

ko00630

All links

Pathway (2)   
   KEGG MODULE (1)   
   BioSystems (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (41)   
   KEGG GENES (41)   
All databases (44)   

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