Valine, leucine and isoleucine degradation

Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:fba00280]

2-oxoisovalerate:ferredoxin oxidoreductase [PATH:fba00280]

Branched-chain amino acid aminotransferase; K00826 branched-chain amino acid aminotransferase [EC:2.6.1.42] [KO:K00826] [EC:2.6.1.42]

aminodeoxychorismate lyase; K00826 branched-chain amino acid aminotransferase [EC:2.6.1.42] [KO:K00826] [EC:2.6.1.42]

2-oxoisovalerate dehydrogenase E1; K11381 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] [KO:K11381] [EC:1.2.4.4]

dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase; K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4] [KO:K00382] [EC:1.8.1.4]

dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase; K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4] [KO:K00382] [EC:1.8.1.4]

3-ketoacyl-CoA thiolase; K00632 acetyl-CoA acyltransferase [EC:2.3.1.16] [KO:K00632] [EC:2.3.1.16]

methylmalonyl-CoA mutase; K01847 methylmalonyl-CoA mutase [EC:5.4.99.2] [KO:K01847] [EC:5.4.99.2]

methylmalonyl-CoA mutase small subunit; K01847 methylmalonyl-CoA mutase [EC:5.4.99.2] [KO:K01847] [EC:5.4.99.2]

B12 binding domain / kinase domain / methylmalonyl-CoA mutase; K11942 methylmalonyl-CoA mutase [EC:5.4.99.2] [KO:K11942] [EC:5.4.99.2]

aldehyde dehydrogenase; K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] [KO:K00128] [EC:1.2.1.3]

aldehyde dehydrogenase; K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] [KO:K00128] [EC:1.2.1.3]

aldehyde dehydrogenase; K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] [KO:K00128] [EC:1.2.1.3]

methylglutaconyl-CoA hydratase; K13766 methylglutaconyl-CoA hydratase [EC:4.2.1.18] [KO:K13766] [EC:4.2.1.18]

Hydroxymethylglutaryl-CoA lyase; K01640 hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4] [KO:K01640] [EC:4.1.3.4]

Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A; K01028 3-oxoacid CoA-transferase subunit A [EC:2.8.3.5] [KO:K01028] [EC:2.8.3.5]

Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B; K01029 3-oxoacid CoA-transferase subunit B [EC:2.8.3.5] [KO:K01029] [EC:2.8.3.5]

acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]

Acetyl-CoA

Thiamin diphosphate

Succinyl-CoA

Propanoyl-CoA

L-Leucine

3-Methyl-2-oxobutanoic acid

Acetoacetate

L-Valine

4-Methyl-2-oxopentanoate

Acetoacetyl-CoA

(S)-3-Hydroxy-3-methylglutaryl-CoA

L-Isoleucine

2-Methylpropanoyl-CoA

(S)-3-Methyl-2-oxopentanoic acid

(S)-Methylmalonyl-CoA

(R)-Methylmalonyl-CoA

Methylmalonate

(3R)-beta-Leucine

3-Methylbutanoyl-CoA

3-Methylcrotonyl-CoA

3-Methylglutaconyl-CoA

L-3-Amino-isobutanoate

2-Methylacetoacetyl-CoA

2-Methylbut-2-enoyl-CoA

2-Methylprop-2-enoyl-CoA

beta-Ketoisocaproate

(2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA

Branched chain fatty acid

3-Hydroxyisovaleryl-CoA

(S)-3-Hydroxyisobutyryl-CoA

(S)-3-Hydroxyisobutyrate

(S)-Methylmalonate semialdehyde

Enzyme N6-(lipoyl)lysine

Enzyme N6-(dihydrolipoyl)lysine

3-Methyl-1-hydroxybutyl-ThPP

[Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine

2-Methyl-1-hydroxypropyl-ThPP

[Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine

2-Methyl-1-hydroxybutyl-ThPP

[Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine

(S)-2-Methylbutanoyl-CoA