KEGG   PATHWAY: ftn00230Help
Entry
ftn00230                    Pathway                                

Name
Purine metabolism - Francisella tularensis subsp. novicida U112
Class
Metabolism; Nucleotide metabolism
BRITE hierarchy
Pathway map
Purine metabolism
ftn00230

All organismsOrtholog table
Module
PRPP biosynthesis, ribose 5P => PRPP [PATH:ftn00230]
Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:ftn00230]
Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ftn00230]
Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:ftn00230]
Other DBs
BSID: 
GO: 
Organism
Francisella tularensis subsp. novicida U112 [GN:ftn]
Gene
K01839 phosphopentomutase [EC:5.4.2.7] | (GenBank) deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
K01835 phosphoglucomutase [EC:5.4.2.2] | (GenBank) pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1] | (GenBank) prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
K00764 amidophosphoribosyltransferase [EC:2.4.2.14] | (GenBank) purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
K13713 fusion protein PurCD [EC:6.3.2.6 6.3.4.13] | (GenBank) SAICAR synthetase/phosphoribosylamine-glycine ligase [KO:K13713] [EC:6.3.4.13 6.3.2.6]
K11175 phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] | (GenBank) purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
K08289 phosphoribosylglycinamide formyltransferase 2 [EC:2.1.2.2] | (GenBank) purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:2.1.2.2]
K01952 phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] | (GenBank) purL; phosphoribosylformylglycinamide synthase [KO:K01952] [EC:6.3.5.3]
K01933 phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] | (GenBank) purM; phosphoribosylformylglycinamide cyclo-ligase [KO:K01933] [EC:6.3.3.1]
K01589 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18] | (GenBank) purK; N5-carboxyaminoimidazole ribonucleotide synthase monomer [KO:K01589] [EC:6.3.4.18]
K01588 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] | (GenBank) purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
K01756 adenylosuccinate lyase [EC:4.3.2.2] | (GenBank) purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
K00602 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] | (GenBank) purH; AICAR transformylase/IMP cyclohydrolase [KO:K00602] [EC:3.5.4.10 2.1.2.3]
K00759 adenine phosphoribosyltransferase [EC:2.4.2.7] | (GenBank) apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
K03784 purine-nucleoside phosphorylase [EC:2.4.2.1] | (GenBank) deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
K00760 hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] | (GenBank) hpt; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
K00088 IMP dehydrogenase [EC:1.1.1.205] | (GenBank) guaB; IMP dehydrogenase/GMP reductase [KO:K00088] [EC:1.1.1.205]
K00940 nucleoside-diphosphate kinase [EC:2.7.4.6] | (GenBank) ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
K02428 XTP/dITP diphosphohydrolase [EC:3.6.1.66] | (GenBank) HAM1-like protein [KO:K02428] [EC:3.6.1.66]
K01951 GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] | (GenBank) glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
K01951 GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] | (GenBank) guaA; GMP synthetase (glutamine-hydrolyzing) [KO:K01951] [EC:6.3.5.2]
K00942 guanylate kinase [EC:2.7.4.8] | (GenBank) gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
K00873 pyruvate kinase [EC:2.7.1.40] | (GenBank) pyk; pyruvate kinase [KO:K00873] [EC:2.7.1.40]
K00525 ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] | (GenBank) nrdA; ribonucleoside-diphosphate reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
K00526 ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] K03676 glutaredoxin 3 | (GenBank) bifunctional protein: glutaredoxin 3/ribonucleotide reductase beta subunit [KO:K00526 K03676] [EC:1.17.4.1]
K01129 dGTPase [EC:3.1.5.1] | (GenBank) dGTP triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
K03040 DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] | (GenBank) rpoA; DNA-directed RNA polymerase, alpha subunit [KO:K03040] [EC:2.7.7.6]
K03040 DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] | (GenBank) DNA-directed RNA polymerase [KO:K03040] [EC:2.7.7.6]
K03043 DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] | (GenBank) rpoB; DNA-directed RNA polymerase, beta subunit/140 kD subunit [KO:K03043] [EC:2.7.7.6]
K03046 DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] | (GenBank) rpoC; DNA-directed RNA polymerase, beta' subunit/160 kD subunit [KO:K03046] [EC:2.7.7.6]
K03060 DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] | (GenBank) rpoZ; DNA-directed RNA polymerase, subunit K/omega [KO:K03060] [EC:2.7.7.6]
K02335 DNA polymerase I [EC:2.7.7.7] | (GenBank) polA; DNA polymerase I [KO:K02335] [EC:2.7.7.7]
K02337 DNA polymerase III subunit alpha [EC:2.7.7.7] | (GenBank) dnaE; DNA polymerase III, alpha subunit [KO:K02337] [EC:2.7.7.7]
K02338 DNA polymerase III subunit beta [EC:2.7.7.7] | (GenBank) dnaN; DNA polymerase III, beta subunit [KO:K02338] [EC:2.7.7.7]
K02343 DNA polymerase III subunit gamma/tau [EC:2.7.7.7] | (GenBank) dnaX; DNA polymerase III, gamma/tau subunits [KO:K02343] [EC:2.7.7.7]
K02340 DNA polymerase III subunit delta [EC:2.7.7.7] | (GenBank) holA; DNA polymerase III, delta subunit [KO:K02340] [EC:2.7.7.7]
K02341 DNA polymerase III subunit delta' [EC:2.7.7.7] | (GenBank) holB; DNA polymerase III, delta prime subunit [KO:K02341] [EC:2.7.7.7]
K02342 DNA polymerase III subunit epsilon [EC:2.7.7.7] | (GenBank) dnaQ; DNA polymerase III, epsilon subunit [KO:K02342] [EC:2.7.7.7]
K02339 DNA polymerase III subunit chi [EC:2.7.7.7] | (GenBank) holC; DNA polymerase III, chi subunit [KO:K02339] [EC:2.7.7.7]
K01524 exopolyphosphatase / guanosine-5'-triphosphate; exopolyphosphatase [KO:K01524] [EC:3.6.1.40 3.6.1.11]
K00951 GTP pyrophosphokinase [EC:2.7.6.5] | (GenBank) relA; GDP pyrophosphokinase/GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
K01939 adenylosuccinate synthase [EC:6.3.4.4] | (GenBank) purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
K01488 adenosine deaminase [EC:3.5.4.4] | (GenBank) add; deoxyadenosine deaminase/adenosine deaminase [KO:K01488] [EC:3.5.4.4]
K00939 adenylate kinase [EC:2.7.4.3] | (GenBank) adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
K00962 polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] | (GenBank) pnp; polyribonucleotide nucleotidyltransferase [KO:K00962] [EC:2.7.7.8]
K01525 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [EC:3.6.1.41] | (GenBank) apaH; diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
K00860 adenylylsulfate kinase [EC:2.7.1.25] | (GenBank) cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
K00956 sulfate adenylyltransferase subunit 1 [EC:2.7.7.4] | (GenBank) cysN; sulfate adenylate transferase, subunit 1 [KO:K00956] [EC:2.7.7.4]
K00957 sulfate adenylyltransferase subunit 2 [EC:2.7.7.4] | (GenBank) cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
Compound
C00002  
ATP
C00008  
ADP
C00011  
CO2
C00014  
Ammonia
C00020  
AMP
C00035  
GDP
C00037  
Glycine
C00039  
DNA
C00044  
GTP
C00046  
RNA
C00048  
Glyoxylate
C00053  
3'-Phosphoadenylyl sulfate
C00054  
Adenosine 3',5'-bisphosphate
C00059  
Sulfate
C00064  
L-Glutamine
C00081  
ITP
C00086  
Urea
C00104  
IDP
C00117  
D-Ribose 5-phosphate
C00119  
5-Phospho-alpha-D-ribose 1-diphosphate
C00130  
IMP
C00131  
dATP
C00144  
GMP
C00147  
Adenine
C00169  
Carbamoyl phosphate
C00206  
dADP
C00212  
Adenosine
C00224  
Adenylyl sulfate
C00242  
Guanine
C00262  
Hypoxanthine
C00286  
dGTP
C00294  
Inosine
C00301  
ADP-ribose
C00330  
Deoxyguanosine
C00360  
dAMP
C00361  
dGDP
C00362  
dGMP
C00366  
Urate
C00385  
Xanthine
C00387  
Guanosine
C00499  
Allantoate
C00559  
Deoxyadenosine
C00575  
3',5'-Cyclic AMP
C00603  
(-)-Ureidoglycolate
C00620  
alpha-D-Ribose 1-phosphate
C00655  
Xanthosine 5'-phosphate
C00700  
XTP
C00802  
Oxalureate
C00942  
3',5'-Cyclic GMP
C01228  
Guanosine 3',5'-bis(diphosphate)
C01260  
P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  
P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  
dIDP
C01345  
dITP
C01367  
3'-AMP
C01762  
Xanthosine
C02091  
(S)-Ureidoglycine
C02348  
(R)(-)-Allantoin
C02350  
(S)-Allantoin
C02353  
2',3'-Cyclic AMP
C02718  
N-Formiminoglycine
C03090  
5-Phosphoribosylamine
C03373  
Aminoimidazole ribotide
C03483  
Adenosine tetraphosphate
C03614  
Inosine 5'-tetraphosphate
C03794  
N6-(1,2-Dicarboxyethyl)-AMP
C03838  
5'-Phosphoribosylglycinamide
C04051  
5-Amino-4-imidazolecarboxyamide
C04376  
5'-Phosphoribosyl-N-formylglycinamide
C04392  
P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  
Guanosine 3'-diphosphate 5'-triphosphate
C04640  
2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  
1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  
1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  
1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  
5-Aminoimidazole
C05512  
Deoxyinosine
C05513  
Urate-3-ribonucleoside
C05515  
5-Ureido-4-imidazole carboxylate
C05516  
5-Amino-4-imidazole carboxylate
C05993  
Acetyl adenylate
C06193  
Guanosine 3'-phosphate
C06194  
2',3'-Cyclic GMP
C06195  
Imidazolone
C06196  
2'-Deoxyinosine 5'-phosphate
C06197  
P1,P3-Bis(5'-adenosyl) triphosphate
C06433  
5'-Benzoylphosphoadenosine
C06435  
5'-Butyrylphosphoinosine
C11821  
5-Hydroxyisourate
C12248  
5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  
5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
Reference
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
Reference
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
KO pathway
 

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