KEGG PATHWAY: gth00230

PATHWAY: gth00230

Entry

gth00230 Pathway

Name

Purine metabolism - Geobacillus thermoglucosidasius

Class

Metabolism; Nucleotide metabolism

Pathway map

gth00230

Purine metabolism

Module

gth_M00005	PRPP biosynthesis, ribose 5P => PRPP [PATH:gth00230]
gth_M00048	Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:gth00230]
gth_M00049	Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:gth00230]
gth_M00050	Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:gth00230]
gth_M00546	Purine degradation, xanthine => urea [PATH:gth00230]

Other DBs

BSID:

373379

GO:

0042278

Organism

Geobacillus thermoglucosidasius [GN:gth]

Gene

Geoth_1347	nucleoside diphosphate pyrophosphatase; K01515 ADP-ribose pyrophosphatase [EC:3.6.1.13] [KO:K01515] [EC:3.6.1.13]
Geoth_1353	phosphopentomutase; K01839 phosphopentomutase [EC:5.4.2.7] [KO:K01839] [EC:5.4.2.7]
Geoth_3288	phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; K01835 phosphoglucomutase [EC:5.4.2.2] [KO:K01835] [EC:5.4.2.2]
Geoth_2081	phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; K15778 phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] [KO:K15778] [EC:5.4.2.2 5.4.2.8]
Geoth_0067	ribose-phosphate pyrophosphokinase; K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1] [KO:K00948] [EC:2.7.6.1]
Geoth_3645	amidophosphoribosyltransferase; K00764 amidophosphoribosyltransferase [EC:2.4.2.14] [KO:K00764] [EC:2.4.2.14]
Geoth_3641	phosphoribosylamine--glycine ligase; K01945 phosphoribosylamine--glycine ligase [EC:6.3.4.13] [KO:K01945] [EC:6.3.4.13]
Geoth_3643	phosphoribosylglycinamide formyltransferase; K11175 phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] [KO:K11175] [EC:2.1.2.2]
Geoth_3646	phosphoribosylformylglycinamidine synthase 2; K01952 phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] [KO:K01952] [EC:6.3.5.3]
Geoth_3647	phosphoribosylformylglycinamidine synthase I; K01952 phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] [KO:K01952] [EC:6.3.5.3]
Geoth_3648	phosphoribosylformylglycinamidine synthase PurS; K01952 phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] [KO:K01952] [EC:6.3.5.3]
Geoth_3644	phosphoribosylformylglycinamidine cyclo-ligase; K01933 phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] [KO:K01933] [EC:6.3.3.1]
Geoth_3651	phosphoribosylaminoimidazole carboxylase ATPase subunit; K01589 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18] [KO:K01589] [EC:6.3.4.18]
Geoth_3652	phosphoribosylaminoimidazole carboxylase catalytic subunit; K01588 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] [KO:K01588] [EC:5.4.99.18]
Geoth_3649	phosphoribosylaminoimidazolesuccinocarboxamide synthase; K01923 phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] [KO:K01923] [EC:6.3.2.6]
Geoth_3650	adenylosuccinate lyase; K01756 adenylosuccinate lyase [EC:4.3.2.2] [KO:K01756] [EC:4.3.2.2]
Geoth_3642	phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; K00602 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] [KO:K00602] [EC:3.5.4.10 2.1.2.3]
Geoth_1059	adenine phosphoribosyltransferase; K00759 adenine phosphoribosyltransferase [EC:2.4.2.7] [KO:K00759] [EC:2.4.2.7]
Geoth_2116	5'-nucleotidase; K01081 5'-nucleotidase [EC:3.1.3.5] [KO:K01081] [EC:3.1.3.5]
Geoth_1354	purine nucleoside phosphorylase I; K03783 purine-nucleoside phosphorylase [EC:2.4.2.1] [KO:K03783] [EC:2.4.2.1]
Geoth_1759	purine nucleoside phosphorylase; K03784 purine-nucleoside phosphorylase [EC:2.4.2.1] [KO:K03784] [EC:2.4.2.1]
Geoth_0084	hypoxanthine phosphoribosyltransferase; K00760 hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] [KO:K00760] [EC:2.4.2.8]
Geoth_0030	inosine-5'-monophosphate dehydrogenase; K00088 IMP dehydrogenase [EC:1.1.1.205] [KO:K00088] [EC:1.1.1.205]
Geoth_1461	nucleoside diphosphate kinase; K00940 nucleoside-diphosphate kinase [EC:2.7.4.6] [KO:K00940] [EC:2.7.4.6]
Geoth_0976	nucleoside-triphosphatase rdgB; K02428 dITP/XTP pyrophosphatase [EC:3.6.1.19] [KO:K02428] [EC:3.6.1.19]
Geoth_1728	xanthine phosphoribosyltransferase; K03816 xanthine phosphoribosyltransferase [EC:2.4.2.22] [KO:K03816] [EC:2.4.2.22]
Geoth_3662	GMP synthase large subunit; K01951 GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] [KO:K01951] [EC:6.3.5.2]
Geoth_2753	guanylate kinase; K00942 guanylate kinase [EC:2.7.4.8] [KO:K00942] [EC:2.7.4.8]
Geoth_0898	pyruvate kinase; K00873 pyruvate kinase [EC:2.7.1.40] [KO:K00873] [EC:2.7.1.40]
Geoth_3220	ribonucleoside-diphosphate reductase subunit alpha; K00525 ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] [KO:K00525] [EC:1.17.4.1]
Geoth_3221	ribonucleotide reductase; K00526 ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] [KO:K00526] [EC:1.17.4.1]
Geoth_0036	Deoxyguanosine kinase; K15518 deoxyguanosine kinase [EC:2.7.1.113] [KO:K15518] [EC:2.7.1.113]
Geoth_0157	DNA-directed RNA polymerase subunit alpha; K03040 DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] [KO:K03040] [EC:2.7.7.6]
Geoth_0122	DNA-directed RNA polymerase subunit beta; K03043 DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] [KO:K03043] [EC:2.7.7.6]
Geoth_0123	DNA-directed RNA polymerase subunit beta'; K03046 DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] [KO:K03046] [EC:2.7.7.6]
Geoth_3838	DNA-directed RNA polymerase subunit delta; K03048 DNA-directed RNA polymerase subunit delta [KO:K03048]
Geoth_2752	DNA-directed RNA polymerase subunit omega; K03060 DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] [KO:K03060] [EC:2.7.7.6]
Geoth_0907	DNA polymerase I; K02335 DNA polymerase I [EC:2.7.7.7] [KO:K02335] [EC:2.7.7.7]
Geoth_0893	DNA polymerase III subunit alpha; K02337 DNA polymerase III subunit alpha [EC:2.7.7.7] [KO:K02337] [EC:2.7.7.7]
Geoth_2662	DNA polymerase III subunit alpha; K03763 DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] [KO:K03763] [EC:2.7.7.7]
Geoth_0023	DNA polymerase III subunit beta; K02338 DNA polymerase III subunit beta [EC:2.7.7.7] [KO:K02338] [EC:2.7.7.7]
Geoth_0039	DNA polymerase III subunits gamma and tau; K02343 DNA polymerase III subunit gamma/tau [EC:2.7.7.7] [KO:K02343] [EC:2.7.7.7]
Geoth_1163	DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta [EC:2.7.7.7] [KO:K02340] [EC:2.7.7.7]
Geoth_0047	DNA polymerase III subunit delta'; K02341 DNA polymerase III subunit delta' [EC:2.7.7.7] [KO:K02341] [EC:2.7.7.7]
Geoth_1617	Exonuclease RNase T and DNA polymerase III; K02342 DNA polymerase III subunit epsilon [EC:2.7.7.7] [KO:K02342] [EC:2.7.7.7]
Geoth_1060	(p)ppGpp synthetase I SpoT/RelA; K00951 GTP pyrophosphokinase [EC:2.7.6.5] [KO:K00951] [EC:2.7.6.5]
Geoth_3036	RelA/SpoT domain-containing protein; K07816 putative GTP pyrophosphokinase [EC:2.7.6.5] [KO:K07816] [EC:2.7.6.5]
Geoth_3926	adenylosuccinate synthetase; K01939 adenylosuccinate synthase [EC:6.3.4.4] [KO:K01939] [EC:6.3.4.4]
Geoth_0035	deoxyadenosine kinase; K15519 deoxyadenosine/deoxycytidine kinase [EC:2.7.1.76 2.7.1.74] [KO:K15519] [EC:2.7.1.74 2.7.1.76]
Geoth_3638	adenine deaminase; K01486 adenine deaminase [EC:3.5.4.2] [KO:K01486] [EC:3.5.4.2]
Geoth_0151	adenylate kinase; K00939 adenylate kinase [EC:2.7.4.3] [KO:K00939] [EC:2.7.4.3]
Geoth_2650	polyribonucleotide nucleotidyltransferase; K00962 polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] [KO:K00962] [EC:2.7.7.8]
Geoth_3458	adenylylsulfate kinase; K00860 adenylylsulfate kinase [EC:2.7.1.25] [KO:K00860] [EC:2.7.1.25]
Geoth_3457	sulfate adenylyltransferase; K00958 sulfate adenylyltransferase [EC:2.7.7.4] [KO:K00958] [EC:2.7.7.4]
Geoth_3976	hydantoin racemase; K16841 allantoin racemase [EC:5.1.99.3] [KO:K16841] [EC:5.1.99.3]
Geoth_0228	amidase; K02083 allantoate deiminase [EC:3.5.3.9] [KO:K02083] [EC:3.5.3.9]
Geoth_2305	urease subunit alpha; K01428 urease subunit alpha [EC:3.5.1.5] [KO:K01428] [EC:3.5.1.5]
Geoth_2306	urease subunit beta; K01429 urease subunit beta [EC:3.5.1.5] [KO:K01429] [EC:3.5.1.5]
Geoth_2307	urease subunit gamma; K01430 urease subunit gamma [EC:3.5.1.5] [KO:K01430] [EC:3.5.1.5]

Compound

C00002	ATP
C00008	ADP
C00011	CO2
C00014	NH3
C00020	AMP
C00035	GDP
C00037	Glycine
C00039	DNA
C00044	GTP
C00046	RNA
C00048	Glyoxylate
C00053	3'-Phosphoadenylyl sulfate
C00054	Adenosine 3',5'-bisphosphate
C00059	Sulfate
C00064	L-Glutamine
C00081	ITP
C00086	Urea
C00104	IDP
C00117	D-Ribose 5-phosphate
C00119	5-Phospho-alpha-D-ribose 1-diphosphate
C00130	IMP
C00131	dATP
C00144	GMP
C00147	Adenine
C00169	Carbamoyl phosphate
C00206	dADP
C00212	Adenosine
C00224	Adenylyl sulfate
C00242	Guanine
C00262	Hypoxanthine
C00286	dGTP
C00294	Inosine
C00301	ADP-ribose
C00330	Deoxyguanosine
C00360	dAMP
C00361	dGDP
C00362	dGMP
C00366	Urate
C00385	Xanthine
C00387	Guanosine
C00499	Allantoate
C00559	Deoxyadenosine
C00575	3',5'-Cyclic AMP
C00603	(-)-Ureidoglycolate
C00620	alpha-D-Ribose 1-phosphate
C00655	Xanthosine 5'-phosphate
C00700	XTP
C00802	Oxalureate
C00942	3',5'-Cyclic GMP
C01228	Guanosine 3',5'-bis(diphosphate)
C01260	P1,P4-Bis(5'-adenosyl) tetraphosphate
C01261	P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344	dIDP
C01345	dITP
C01367	3'-AMP
C01762	Xanthosine
C02091	(S)-Ureidoglycine
C02348	(R)(-)-Allantoin
C02350	(S)(+)-Allantoin
C02353	2',3'-Cyclic AMP
C02718	N-Formiminoglycine
C03090	5-Phosphoribosylamine
C03373	Aminoimidazole ribotide
C03483	Adenosine tetraphosphate
C03614	Inosine 5'-tetraphosphate
C03794	N6-(1,2-Dicarboxyethyl)-AMP
C03838	5'-Phosphoribosylglycinamide
C04051	5-Amino-4-imidazolecarboxyamide
C04376	5'-Phosphoribosyl-N-formylglycinamide
C04392	P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494	Guanosine 3'-diphosphate 5'-triphosphate
C04640	2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677	1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734	1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751	1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823	1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239	5-Aminoimidazole
C05512	Deoxyinosine
C05513	Urate-3-ribonucleoside
C05515	5-Ureido-4-imidazole carboxylate
C05516	5-Amino-4-imidazole carboxylate
C05993	Acetyl adenylate
C06193	Guanosine 3'-phosphate
C06194	2',3'-Cyclic GMP
C06195	Imidazolone
C06196	2'-Deoxyinosine 5'-phosphate
C06197	P1,P3-Bis(5'-adenosyl) triphosphate
C06433	5'-Benzoylphosphoadenosine
C06435	5'-Butyrylphosphoinosine
C11821	5-Hydroxyisourate
C12248	5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667	5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole

Reference

PMID:10601204

Authors

Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.

Title

Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.

Journal

J Bacteriol 181:7479-84 (1999)

Reference

PMID:10986234

Authors

Xi H, Schneider BL, Reitzer L.

Title

Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.

Journal

J Bacteriol 182:5332-41 (2000)

KO pathway

ko00230

All links

Pathway (5)   
   KEGG MODULE (4)   
   BioSystems (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (59)   
   KEGG GENES (59)   
All databases (65)   

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