KEGG   PATHWAY: hah00630
Entry
hah00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Halophilic archaeon DL31
Class
Metabolism; Carbohydrate metabolism
Pathway map
hah00630  Glyoxylate and dicarboxylate metabolism
hah00630

Module
hah_M00621  Glycine cleavage system [PATH:hah00630]
hah_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:hah00630]
hah_M00968  Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate [PATH:hah00630]
Other DBs
GO: 0046487 0043648
Organism
Halophilic archaeon DL31 [GN:hah]
Gene
Halar_0840  acetate/CoA ligase [KO:K01895] [EC:6.2.1.1]
Halar_2632  Acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
Halar_2281  L-lactate dehydrogenase [KO:K00024] [EC:1.1.1.37]
Halar_3296  2-methylcitrate synthase/citrate synthase II [KO:K01647] [EC:2.3.3.1]
Halar_1908  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
Halar_1165  Propanoyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
Halar_3556  Propanoyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
Halar_3616  Propanoyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
Halar_1372  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Halar_1727  Carbamoyl-phosphate synthase L chain ATP-binding protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
Halar_1885  Propionyl-CoA carboxylase [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
Halar_1886  hypothetical protein [KO:K22568] [EC:6.4.1.2 6.4.1.3]
Halar_3651  Methylmalonyl-CoA mutase domain-containing protein [KO:K01849] [EC:5.4.99.2]
Halar_1374  methylmalonyl-CoA mutase, large subunit [KO:K01848] [EC:5.4.99.2]
Halar_0842  methylmalonyl-CoA mutase, large subunit [KO:K01848] [EC:5.4.99.2]
Halar_2094  HAD-superfamily hydrolase, subfamily IA, variant 3 [KO:K01091] [EC:3.1.3.18]
Halar_1459  Phosphoglycolate phosphatase [KO:K22223] [EC:3.1.3.18]
Halar_1625  Serine--pyruvate transaminase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
Halar_3184  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
Halar_1721  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Halar_2083  Glycine dehydrogenase (decarboxylating) [KO:K00282] [EC:1.4.4.2]
Halar_2084  Glycine cleavage system P-protein [KO:K00283] [EC:1.4.4.2]
Halar_0895  folate-binding protein YgfZ [KO:K00605] [EC:2.1.2.10]
Halar_2081  Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
Halar_2852  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Halar_2082  Glycine cleavage system H protein [KO:K02437]
Halar_1483  Hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
Halar_0932  HAD-superfamily hydrolase, subfamily IA, variant 1 [KO:K26210] [EC:3.1.3.109]
Halar_0933  class II aldolase/adducin family protein [KO:K01636] [EC:4.1.2.-]
Halar_1242  Nitrate reductase [KO:K00123] [EC:1.17.1.9]
Halar_1646  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
Halar_1241  4Fe-4S ferredoxin iron-sulfur binding domain-containing protein [KO:K00124]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
hah00010  Glycolysis / Gluconeogenesis
hah00020  Citrate cycle (TCA cycle)
hah00030  Pentose phosphate pathway
hah00053  Ascorbate and aldarate metabolism
hah00071  Fatty acid degradation
hah00230  Purine metabolism
hah00250  Alanine, aspartate and glutamate metabolism
hah00260  Glycine, serine and threonine metabolism
hah00620  Pyruvate metabolism
hah00750  Vitamin B6 metabolism
hah00910  Nitrogen metabolism
KO pathway
ko00630   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (32)   
   KEGG GENES (32)   
All databases (33)   

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