KEGG   PATHWAY: hit00564Help
Entry
hit00564                    Pathway                                
Name
Glycerophospholipid metabolism - Haemophilus influenzae 86-028NP (nontypeable)
Class
Metabolism; Lipid metabolism
BRITE hierarchy
Pathway map
Glycerophospholipid metabolism
hit00564

All organismsOrtholog table
Module
Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:hit00564]
Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:hit00564]
Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:hit00564]
Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:hit00564]
Other DBs
Organism
Haemophilus influenzae 86-028NP (nontypeable) [GN:hit]
Gene
gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [KO:K00057] [EC:1.1.1.94]
glpA; sn-glycerol-3-phosphate dehydrogenase subunit A [KO:K00111] [EC:1.1.5.3]
glpB; anaerobic glycerol-3-phosphate dehydrogenase subunit B [KO:K00112] [EC:1.1.5.3]
glpC; sn-glycerol-3-phosphate dehydrogenase subunit C [KO:K00113] [EC:1.1.5.3]
plsB; glycerol-3-phosphate acyltransferase [KO:K00631] [EC:2.3.1.15]
glycerol-3-phosphate acyltransferase PlsY; K08591 glycerol-3-phosphate acyltransferase PlsY [EC:2.3.1.15] [KO:K08591] [EC:2.3.1.15]
plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [KO:K00655] [EC:2.3.1.51]
dgkA; diacylglycerol kinase [KO:K00901] [EC:2.7.1.107]
pldB; lysophospholipase L2 [KO:K01048] [EC:3.1.1.5]
glpQ; glycerophosphodiester phosphodiesterase [KO:K01126] [EC:3.1.4.46]
cdsA; phosphatidate cytidylyltransferase [KO:K00981] [EC:2.7.7.41]
pssA; phosphatidylserine synthase [KO:K00998] [EC:2.7.8.8]
psd; phosphatidylserine decarboxylase [KO:K01613] [EC:4.1.1.65]
pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [KO:K00995] [EC:2.7.8.5]
pgpA; phosphatidylglycerophosphatase A [KO:K01095] [EC:3.1.3.27]
pgpB; phosphatidylglycerophosphatase B [KO:K01096] [EC:3.1.3.27]
Compound
C00040  
Acyl-CoA
C00084  
Acetaldehyde
C00093  
sn-Glycerol 3-phosphate
C00111  
Glycerone phosphate
C00114  
Choline
C00157  
Phosphatidylcholine
C00189  
Ethanolamine
C00269  
CDP-diacylglycerol
C00307  
CDP-choline
C00344  
Phosphatidylglycerol
C00346  
Ethanolamine phosphate
C00350  
Phosphatidylethanolamine
C00416  
Phosphatidate
C00513  
CDP-glycerol
C00570  
CDP-ethanolamine
C00588  
Choline phosphate
C00641  
1,2-Diacyl-sn-glycerol
C00670  
sn-glycero-3-Phosphocholine
C00681  
1-Acyl-sn-glycerol 3-phosphate
C01194  
1-Phosphatidyl-D-myo-inositol
C01210  
N-Methylethanolamine phosphate
C01233  
sn-glycero-3-Phosphoethanolamine
C01241  
Phosphatidyl-N-methylethanolamine
C01996  
Acetylcholine
C02737  
Phosphatidylserine
C03372  
Acylglycerone phosphate
C03819  
1-Acylglycerophosphoinositol
C03872  
L-Serine-phosphoethanolamine
C03892  
Phosphatidylglycerophosphate
C03974  
2-Acyl-sn-glycerol 3-phosphate
C04230  
1-Acyl-sn-glycero-3-phosphocholine
C04233  
2-Acyl-sn-glycero-3-phosphocholine
C04308  
Phosphatidyl-N-dimethylethanolamine
C04438  
1-Acyl-sn-glycero-3-phosphoethanolamine
C05973  
2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  
2-Acyl-sn-glycero-3-phosphoserine
C05976  
Aminoacyl-phosphatidylglycerol
C05980  
Cardiolipin
C06771  
Triethanolamine
C06772  
Diethanolamine
C13482  
Phosphodimethylethanolamine
C18125  
1-Acyl-sn-glycero-3-phosphoserine
C18126  
1-Acyl-sn-glycero-3-phosphoglycerol
C18129  
Monolysocardiolipin
C18168  
Diacylglycerylhomoserine
C18169  
Diacylglyceryl-N,N,N-trimethylhomoserine
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
Reference
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
Reference
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
Reference
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
Reference
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
Reference
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO.
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
KO pathway
 
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