KEGG PATHWAY: hsa00604

PATHWAY: hsa00604

Entry

hsa00604 Pathway

Name

Glycosphingolipid biosynthesis - ganglio series - Homo sapiens (human)

Class

Metabolism; Glycan biosynthesis and metabolism

Pathway map

hsa00604

Glycosphingolipid biosynthesis - ganglio series

Module

hsa_M00069

Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 [PATH:hsa00604]

Disease

H00124	GM2 gangliosidoses
H00281	GM1 gangliosidosis
H00426	Defects in the degradation of ganglioside
H00996	Amish infantile epilepsy syndrome

Organism

Homo sapiens (human) [GN:hsa]

Gene

2583	B4GALNT1; beta-1,4-N-acetyl-galactosaminyltransferase 1 [KO:K00725] [EC:2.4.1.92]
8705	B3GALT4; beta-1,3-galactosyltransferase 4 [KO:K00715] [EC:2.4.1.62]
6483	ST3GAL2; ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [KO:K03368] [EC:2.4.99.4]
6482	ST3GAL1; ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [KO:K00780] [EC:2.4.99.4]
29906	ST8SIA5; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 [KO:K03369] [EC:2.4.99.-]
8869	ST3GAL5; ST3 beta-galactoside alpha-2,3-sialyltransferase 5 [KO:K03370] [EC:2.4.99.9]
6489	ST8SIA1; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 [KO:K03371] [EC:2.4.99.8]
9197	SLC33A1; solute carrier family 33 member 1 [KO:K03372] [EC:2.3.1.-]
256435	ST6GALNAC3; ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 [KO:K03373] [EC:2.4.99.-]
27090	ST6GALNAC4; ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 [KO:K03374] [EC:2.4.99.7]
81849	ST6GALNAC5; ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 [KO:K03375] [EC:2.4.99.-]
30815	ST6GALNAC6; ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 [KO:K03376] [EC:2.4.99.-]
2720	GLB1; galactosidase beta 1 [KO:K12309] [EC:3.2.1.23]
3073	HEXA; hexosaminidase subunit alpha [KO:K12373] [EC:3.2.1.52]
3074	HEXB; hexosaminidase subunit beta [KO:K12373] [EC:3.2.1.52]

Compound

G00092	Lactosylceramide
G00108	GM3
G00109	GM2
G00110	GM1
G00111	GD1a
G00112	GT1a
G00113	GD3
G00114	GD2
G00115	GD1b
G00116	GT1b
G00117	GQ1b
G00118	GT3
G00119	GT2
G00120	GT1c
G00121	GQ1c
G00122	GP1c
G00123	GA2
G00124	GA1
G00125	GM1b
G00126	GD1c
G00127	GD1a
G00128	GT1aalpha
G00129	GQ1balpha
G00130	GM2alpha
G00131	GM1alpha
G00132	GD1beta
G00166	Fucosyl-GM1
G00167	N-Acetylgalactosaminyl GM1b
G00168	N-Acetylgalactosaminyl GD1a
G00169	9-O-Acetylated GD3
G00170	9-O-Acetylated GT3

KO pathway

ko00604

All links

Pathway (1)   
   BioSystems (1)   
Disease (4)   
   KEGG DISEASE (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG GENES (15)   
All databases (21)   

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